Chromium - Xywav (Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate) Interaction
Herbal: Chromium
Drug: Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate
Brand names:
Xywav
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 11, 2025
Interaction Details
There were no interactions found between Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate and Chromium. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Chromium Overview
Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control.
There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.
Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate Overview
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Calcium, magnesium, potassium, and sodium oxybate is used to treat attacks of cataplexy (episodes of muscle weakness that begin suddenly and last for a short time) and excessive daytime sleepiness in adults and children 7 years of age and older who have narcolepsy (a sleep disorder that may cause extreme sleepiness, sudden uncontrollable urge to sleep during daily activities, and cataplexy). Calcium, magnesium, potassium, and sodium oxybate is also used to treat adults who have idiopathic hypersomnia (IH; a sleep disorder that may cause excessive daytime sleepiness and uncontrollable urge to sleep during daily activities despite adequate or prolonged nighttime sleep). Calcium, magnesium, potassium, and sodium oxybate is in a class of medications called central nervous system depressants. Calcium, magnesium, potassium, and sodium oxybate works to treat narcolepsy, cataplexy, and idiopathic hypersomnia by reducing activity in the brain.
Chromium - More Interactions
Chromium interacts with 176 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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