Medication interaction hub

What Supplements Interact with Glofitamab-gxbm?

Glofitamab-gxbm brand name: Columvi. Every interaction below applies to the brands too.

76 Interactions 71 Moderate 5 Minor
Curated & coded by · Clinical Pharmacist · Updated September 15, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Glofitamab-gxbm? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Glofitamab-gxbm against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Glofitamab-gxbm (Columvi), an immunotherapy that treats aggressive B-cell lymphoma by steering your own T cells at the cancer, has a supplement list that calls for attentiveness rather than alarm. None of the 76 ingredients on file carries a major rating; 71 sit at moderate and 5 at minor. The dominant pattern, covering 53 of them, is immune stimulation: popular herbs like ashwagandha may rev up immune activity, which in theory could work against a therapy built to control immune cells with precision.

The remaining entries mostly involve liver enzymes. Glofitamab can slow the pathways that clear certain supplements, so the caffeine in black tea or the CBD in a gummy may linger longer and hit harder than expected. Nearly all of this evidence is theoretical, drawn from lab and animal studies, but with a lymphoma treatment this consequential, I would still run each bottle past the oncology pharmacist first.

— , Clinical Pharmacist · July 18, 2026

Moderate 71 Minor 5 No known interaction 1,376

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Glofitamab-gxbm: Top Interactions at a Glance

The most significant Glofitamab-gxbm supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 76 interacting ingredients — plus 1,376 more checked with no known interaction. See the complete ranked list.

Start here

The Moderate Interactions to Know About

The most clinically significant Glofitamab-gxbm + supplement combinations in our database, best-documented first. Open any card for the full report.

Moderate Likelihood Probable Yohimbe + Glofitamab-gxbmi

CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.

Read the full interaction Moderate Likelihood Possible Active Hexose Correlated Compound (ahcc) + Glofitamab-gxbmi

Theoretically, taking AHCC might decrease the effects of immunosuppressant drugs.

Read the full interaction Moderate Likelihood Possible Adrafinil + Glofitamab-gxbmi

Theoretically, drugs that inhibit CYP3A4 might increase the levels and clinical effects of adrafinil.

Read the full interaction Moderate Likelihood Possible Alfalfa + Glofitamab-gxbmi

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Read the full interaction Moderate Likelihood Possible American Ginseng + Glofitamab-gxbmi

Theoretically, American ginseng use might interfere with immunosuppressive therapy.

Read the full interaction Moderate Likelihood Possible Andrographis + Glofitamab-gxbmi

Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Glofitamab-gxbm

All 1,452 ingredients in our database, ranked by severity — 76 with a Glofitamab-gxbm interaction on file and 1,376 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Glofitamab-gxbm?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Andrographis with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.

Full Andrographis + Glofitamab-gxbm answer

Can you take Beta-glucans with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, beta-glucans might interfere with immunosuppressive therapy.

Full Beta-glucans + Glofitamab-gxbm answer

Can you take Black Hoof Mushroom with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black hoof mushroom might reduce the effects of immunosuppressant medications.

Full Black Hoof Mushroom + Glofitamab-gxbm answer

Can you take Black Seed with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black seed might interfere with immunosuppressive therapy.

Full Black Seed + Glofitamab-gxbm answer

Can you take Black Tea with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Black Tea + Glofitamab-gxbm answer

Can you take Blood Irradiation Therapy with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research suggests that blood irradiation therapy may stimulate immune function in some patients.

Full Blood Irradiation Therapy + Glofitamab-gxbm answer

Can you take Blue-green Algae with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.

Full Blue-green Algae + Glofitamab-gxbm answer

Can you take Boswellia Serrata with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.

Full Boswellia Serrata + Glofitamab-gxbm answer

Can you take Bupleurum with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, bupleurum might decrease the effects of immunosuppressants.

Full Bupleurum + Glofitamab-gxbm answer

Can you take Cannabidiol (cbd) with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase cannabidiol levels.

Full Cannabidiol (cbd) + Glofitamab-gxbm answer

Can you take Cannabinol (cbn) with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and clinical effects of cannabinol.

Full Cannabinol (cbn) + Glofitamab-gxbm answer

Can you take Cannabis with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of cannabis.

Full Cannabis + Glofitamab-gxbm answer

Can you take Cat's Claw with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cat's claw might interfere with immunosuppressive therapy.

Full Cat's Claw + Glofitamab-gxbm answer

Can you take Catechu with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, catechu might interfere with immunosuppressant therapy.

Full Catechu + Glofitamab-gxbm answer

Can you take Ceylon Leadwort with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Plumbagin, a constituent of Ceylon leadwort, has demonstrated immunosuppressant activity in animal research.

Full Ceylon Leadwort + Glofitamab-gxbm answer

Can you take Chaga with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chaga might interfere with immunosuppressive therapy.

Full Chaga + Glofitamab-gxbm answer

Can you take Cocoa with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Cocoa + Glofitamab-gxbm answer

Can you take Cola Nut with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP1A2 inhibitors might increase the levels and adverse effects of the caffeine in cola nut.

Full Cola Nut + Glofitamab-gxbm answer

Can you take Cordyceps with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.

Full Cordyceps + Glofitamab-gxbm answer

Can you take Delta-9-tetrahydrocannabinol (thc) with Glofitamab-gxbm?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and clinical effects of THC.

Full Delta-9-tetrahydrocannabinol (thc) + Glofitamab-gxbm answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Glofitamab-gxbm is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Glofitamab-gxbm, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Glofitamab-gxbm sits in 6 interaction categories. Open any one to see what the group means:

Immunosuppressants 53 ingredients

Medications that damp down the immune system. Supplements that stimulate immunity can work against them.

53 of the supplement ingredients on this page reach Glofitamab-gxbm through this category.

Cytochrome P450 3A4 (Cyp3A4) Inhibitors 13 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

13 of the supplement ingredients on this page reach Glofitamab-gxbm through this category.

Cytochrome P450 1A2 (Cyp1A2) Inhibitors 10 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

10 of the supplement ingredients on this page reach Glofitamab-gxbm through this category.

Cytochrome P450 2C9 (Cyp2C9) Inhibitors 4 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

4 of the supplement ingredients on this page reach Glofitamab-gxbm through this category.

Cytochrome P450 2D6 (Cyp2D6) Inhibitors 3 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

3 of the supplement ingredients on this page reach Glofitamab-gxbm through this category.

Cytochrome P450 2C19 (Cyp2C19) Inhibitors 2 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

2 of the supplement ingredients on this page reach Glofitamab-gxbm through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Glofitamab-gxbm

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Glofitamab-gxbm.

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Pharmacist Counseling Corner

Glofitamab-gxbm & Supplements: Common Questions

What supplements interact with Glofitamab-gxbm?
More than you might expect — 76 in total, though they are far from equal: 0 are rated major, 71 moderate, and 5 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Yohimbe, Active Hexose Correlated Compound (ahcc), Adrafinil.
Which Glofitamab-gxbm supplement interactions are the most serious?
None of the Glofitamab-gxbm supplement interactions on file are currently rated major. The most significant are the 71 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Glofitamab-gxbm?
Usually yes — most people on Glofitamab-gxbm can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Columvi have the same supplement interactions as Glofitamab-gxbm?
Yes — Columvi all contain Glofitamab-gxbm, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Glofitamab-gxbm and my other medications?
This page covers Glofitamab-gxbm against supplements and herbal ingredients. Checking Glofitamab-gxbm against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.