Medication interaction hub

What Supplements Interact with Fluvoxamine?

Fluvoxamine brand name: Luvox. Every interaction below applies to the brands too.

193 Interactions 2 Major 151 Moderate 40 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Fluvoxamine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Fluvoxamine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Fluvoxamine (Luvox), an SSRI used for OCD and depression, carries an interaction list that deserves genuinely careful reading. Two entries matter most: lithium, which alongside a serotonin-raising drug like fluvoxamine can tip toward serotonin syndrome, a dangerous excess of serotonin, and activated charcoal, which can soak up the medication and reduce how much you absorb. Much of the rest traces back to fluvoxamine's strong brake on the liver enzymes that clear other substances; caffeine is the clearest everyday example, since fluvoxamine slows its breakdown and a normal coffee habit can feel like a much bigger one.

Of the 193 ingredients here, only those two are rated major, with 151 moderate and 40 minor. About twenty add sun sensitivity, and a few bulking fibers can blunt absorption of anything swallowed, so keep those well apart from your dose. Start with the majors, then check the moderates against what you take.

— , Clinical Pharmacist · July 18, 2026

Major 2 Moderate 151 Minor 40 No known interaction 1,259

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Fluvoxamine: Top Interactions at a Glance

The Fluvoxamine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 193 interacting ingredients — plus 1,259 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Fluvoxamine Combinations Today

The Fluvoxamine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Possible Ashwagandha + Fluvoxaminei

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.

Read the full interaction Moderate Likelihood Possible Panax Notoginseng + Fluvoxaminei

Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.

Read the full interaction Moderate Likelihood Possible Zizyphus + Fluvoxaminei

Theoretically, zizyphus might decrease the levels and clinical effects of drugs metabolized by CYP1A2.

Read the full interaction Moderate Likelihood Possible L-tryptophan + Fluvoxaminei

Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.

Read the full interaction Major Likelihood Probable Activated Charcoal + Fluvoxaminei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Lithium + Fluvoxaminei

Theoretically, taking lithium supplements with serotonergic drugs might both mask and increase the risk of serotonin syndrome.

Read the full interaction
The complete list

Every Supplement Checked Against Fluvoxamine

All 1,452 ingredients in our database, ranked by severity — 193 with a Fluvoxamine interaction on file and 1,259 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Fluvoxamine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Ashwagandha with Fluvoxamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.

Full Ashwagandha + Fluvoxamine answer

Can you take Panax Notoginseng with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.

Full Panax Notoginseng + Fluvoxamine answer

Can you take Zizyphus with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, zizyphus might decrease the levels and clinical effects of drugs metabolized by CYP1A2.

Full Zizyphus + Fluvoxamine answer

Can you take L-tryptophan with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining L-tryptophan with serotonergic drugs might cause additive serotonergic effects.

Full L-tryptophan + Fluvoxamine answer

Can you take Fermented Wheat Germ Extract with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of fermented wheat germ extract with serotonergic medications may increase the risk of serotonergic adverse e...

Full Fermented Wheat Germ Extract + Fluvoxamine answer

Can you take Fever Bark with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fever bark might increase the levels and clinical effects of CYP2D6 substrates.

Full Fever Bark + Fluvoxamine answer

Can you take Feverfew with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.

Full Feverfew + Fluvoxamine answer

Can you take Fig with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fig might increase the risk of photosensitivity when used in combination with photosensitizing drugs.

Full Fig + Fluvoxamine answer

Can you take Fo-ti with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2D6.

Full Fo-ti + Fluvoxamine answer

Can you take Garcinia with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin sy...

Full Garcinia + Fluvoxamine answer

Can you take German Chamomile with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.

Full German Chamomile + Fluvoxamine answer

Can you take Ginkgo with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.

Full Ginkgo + Fluvoxamine answer

Can you take Goji with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.

Full Goji + Fluvoxamine answer

Can you take Grape with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.

Full Grape + Fluvoxamine answer

Can you take Grapefruit with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP1A2.

Full Grapefruit + Fluvoxamine answer

Can you take Greater Celandine with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Research in vitro shows that chelidonine, a constituent of greater celandine, inhibits cytochrome P450 2D6 (CYP2D6) enzyme activity.

Full Greater Celandine + Fluvoxamine answer

Can you take Griffonia Simplicifolia with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Griffonia simplicifolia seed extract with antidepressant drugs might increase the risk of serotonergic adverse effects...

Full Griffonia Simplicifolia + Fluvoxamine answer

Can you take Guar Gum with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.

Full Guar Gum + Fluvoxamine answer

Can you take Gum Arabic with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.

Full Gum Arabic + Fluvoxamine answer

Can you take Gymnema with Fluvoxamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.

Full Gymnema + Fluvoxamine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Fluvoxamine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Fluvoxamine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Fluvoxamine sits in 14 interaction categories. Open any one to see what the group means:

Cytochrome P450 1A2 (Cyp1A2) Substrates 79 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

79 of the supplement ingredients on this page reach Fluvoxamine through this category.

Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

60 of the supplement ingredients on this page reach Fluvoxamine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Fluvoxamine through this category.

Serotonergic Drugs 20 ingredients

Medications that raise serotonin activity. Combining them with serotonin-active supplements can, in rare cases, push serotonin too high.

20 of the supplement ingredients on this page reach Fluvoxamine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Fluvoxamine through this category.

Fluvoxamine (Luvox) 14 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

14 of the supplement ingredients on this page reach Fluvoxamine through this category.

Cytochrome P450 3A4 (Cyp3A4) Inhibitors 13 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

13 of the supplement ingredients on this page reach Fluvoxamine through this category.

Cytochrome P450 1A2 (Cyp1A2) Inhibitors 10 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

10 of the supplement ingredients on this page reach Fluvoxamine through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Fluvoxamine through this category.

Cytochrome P450 2C9 (Cyp2C9) Inhibitors 4 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

4 of the supplement ingredients on this page reach Fluvoxamine through this category.

Antidepressant Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Fluvoxamine through this category.

Cytochrome P450 2C19 (Cyp2C19) Inhibitors 2 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

2 of the supplement ingredients on this page reach Fluvoxamine through this category.

Cytochrome P450 1A2 (Cyp1A2) Substrates 1 ingredient

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

1 of the supplement ingredient on this page reaches Fluvoxamine through this category.

Serotonergic Drugs 1 ingredient

Medications that raise serotonin activity. Combining them with serotonin-active supplements can, in rare cases, push serotonin too high.

1 of the supplement ingredient on this page reaches Fluvoxamine through this category.

About Fluvoxamine

Fluvoxamine is an SSRI antidepressant used to treat obsessive-compulsive disorder and social anxiety disorder.

Generic name: Fluvoxamine  ·  Brand name: Luvox.

See the full Fluvoxamine drug information

Related: does Fluvoxamine deplete any nutrients?

Fluvoxamine has 1 reported nutrient association in the research literature — see the Fluvoxamine nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Fluvoxamine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Fluvoxamine.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Fluvoxamine & Supplements: Common Questions

What supplements interact with Fluvoxamine?
Our database currently documents 193 ingredients with a known Fluvoxamine interaction (2 major, 151 moderate, 40 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 193. The highest-ranked right now: Activated Charcoal, Lithium, Ayahuasca.
Which Fluvoxamine supplement interactions are the most serious?
The 2 major-rated combinations — led by Activated Charcoal and Lithium — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Fluvoxamine?
Plenty of supplements coexist fine with Fluvoxamine; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Luvox have the same supplement interactions as Fluvoxamine?
Yes — Luvox all contain Fluvoxamine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Fluvoxamine deplete any vitamins or nutrients?
It might — Fluvoxamine has 1 reported nutrient-depletion association in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Fluvoxamine nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Fluvoxamine and my other medications?
This page covers Fluvoxamine against supplements and herbal ingredients. Checking Fluvoxamine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Fluvoxamine drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.