Medication interaction hub

What Supplements Interact with Moclobemide?

Moclobemide brand names: Moclobemide, Manerix. Every interaction below applies to the brands too.

94 Interactions 13 Major 67 Moderate 14 Minor
Curated & coded by · Clinical Pharmacist · Updated September 24, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Moclobemide? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Moclobemide against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

94 supplements and herbal ingredients have interactions with Moclobemide on file in the HelloPharmacist interaction database — 13 rated major, 67 moderate, and 14 minor. The most serious involve Brewer's Yeast, Fever Bark, Soy, Tyramine and Yohimbe.

Our assessment: with 13 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Moclobemide.

Major 13 Moderate 67 Minor 14 No known interaction 1,358

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Moclobemide: Top Interactions at a Glance

The Moclobemide supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 94 interacting ingredients — plus 1,358 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Moclobemide Combinations Today

The Moclobemide + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Phenylalanine + Moclobemidei

Theoretically, concomitant use of L-phenylalanine and non-selective MAOIs might increase the risk of hypertensive crisis.

Read the full interaction Moderate Likelihood Possible Devil's Claw + Moclobemidei

Theoretically, devil's claw might increase levels of drugs metabolized by CYP2C19.

Read the full interaction Major Likelihood Probable Bitter Orange + Moclobemidei

Theoretically, taking MAOIs with synephrine-containing bitter orange preparations might increase the hypertensive effects of synephrine, potentially leading to...

Read the full interaction Moderate Likelihood Possible Coffee + Moclobemidei

Theoretically, concomitant use might increase the risk of a hypertensive crisis.

Read the full interaction Moderate Likelihood Possible Caffeine + Moclobemidei

Theoretically, concomitant use might increase the risk of a hypertensive crisis.

Read the full interaction Major Likelihood Likely Soy + Moclobemidei

Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.

Read the full interaction
The complete list

Every Supplement Checked Against Moclobemide

All 1,452 ingredients in our database, ranked by severity — 94 with a Moclobemide interaction on file and 1,358 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Moclobemide?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Phenylalanine with Moclobemide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of L-phenylalanine and non-selective MAOIs might increase the risk of hypertensive crisis.

Full Phenylalanine + Moclobemide answer

Can you take Devil's Claw with Moclobemide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, devil's claw might increase levels of drugs metabolized by CYP2C19.

Full Devil's Claw + Moclobemide answer

Can you take Bitter Orange with Moclobemide?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, taking MAOIs with synephrine-containing bitter orange preparations might increase the hypertensive effects of synephrine, pot...

Full Bitter Orange + Moclobemide answer

Can you take Coffee with Moclobemide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk of a hypertensive crisis.

Full Coffee + Moclobemide answer

Can you take Caffeine with Moclobemide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk of a hypertensive crisis.

Full Caffeine + Moclobemide answer

Can you take Yerba Mate with Moclobemide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, the caffeine in yerba mate might increase risk of a hypertensive crisis when used concomitantly with MAOIs.

Full Yerba Mate + Moclobemide answer

Can you take Thyroid Extract with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Food and medications can interfere with thyroid hormone absorption.

Full Thyroid Extract + Moclobemide answer

Can you take Agar with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.

Full Agar + Moclobemide answer

Can you take Algin with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, algin can alter the absorption of oral drugs.

Full Algin + Moclobemide answer

Can you take Black Psyllium with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Full Black Psyllium + Moclobemide answer

Can you take Blond Psyllium with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Full Blond Psyllium + Moclobemide answer

Can you take Carob with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, carob might also impair the absorption of oral drugs.

Full Carob + Moclobemide answer

Can you take Eurycoma Longifolia with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.

Full Eurycoma Longifolia + Moclobemide answer

Can you take Hibiscus Sabdariffa with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Hibiscus sabdariffa extract might reduce the metabolism of CYP2C19 substrates.

Full Hibiscus Sabdariffa + Moclobemide answer

Can you take Karaya Gum with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...

Full Karaya Gum + Moclobemide answer

Can you take Kratom with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, kratom might increase the levels of drugs metabolized by CYP2C19.

Full Kratom + Moclobemide answer

Can you take Marshmallow with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Full Marshmallow + Moclobemide answer

Can you take Rhodiola with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, rhodiola might increase the risk of adverse effects when taken with antidepressants.

Full Rhodiola + Moclobemide answer

Can you take Xanthan Gum with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.

Full Xanthan Gum + Moclobemide answer

Can you take Red Clover with Moclobemide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, red clover might increase the levels and clinical effects of drugs metabolized by CYP2C19.

Full Red Clover + Moclobemide answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Moclobemide is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Moclobemide, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Moclobemide sits in 5 interaction categories. Open any one to see what the group means:

Monoamine Oxidase Inhibitors (Maois) 42 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

42 of the supplement ingredients on this page reach Moclobemide through this category.

Cytochrome P450 2C19 (Cyp2C19) Substrates 33 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

33 of the supplement ingredients on this page reach Moclobemide through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Moclobemide through this category.

Antidepressant Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Moclobemide through this category.

Cytochrome P450 2D6 (Cyp2D6) Inhibitors 3 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

3 of the supplement ingredients on this page reach Moclobemide through this category.

Related: does Moclobemide deplete any nutrients?

Moclobemide has 2 reported nutrient associations in the research literature — see the Moclobemide nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Moclobemide

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Moclobemide.

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Pharmacist Counseling Corner

Moclobemide & Supplements: Common Questions

What supplements interact with Moclobemide?
In our interaction database, 94 supplement and herbal ingredients have an interaction with Moclobemide on file — 13 rated major, 67 moderate, and 14 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Brewer's Yeast, Fever Bark, Soy.
Which Moclobemide supplement interactions are the most serious?
The 13 major-rated combinations — led by Brewer's Yeast, Fever Bark, Soy, Tyramine and Yohimbe — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Moclobemide?
That depends entirely on which supplement. The honest answer for Moclobemide is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Moclobemide have the same supplement interactions as Moclobemide?
Yes — Moclobemide, Manerix all contain Moclobemide, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Moclobemide deplete any vitamins or nutrients?
It might — Moclobemide has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Moclobemide nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Moclobemide and my other medications?
This page covers Moclobemide against supplements and herbal ingredients. Checking Moclobemide against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 24, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.