What Supplements Interact with Nebivolol Hydrochloride, Valsartan?
Nebivolol Hydrochloride, Valsartan brand name: Byvalson. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Nebivolol Hydrochloride, Valsartan? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Nebivolol Hydrochloride, Valsartan against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
What is this?
The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.Nebivolol with valsartan (Byvalson) packs two blood pressure medicines into one pill, and I would treat this list with genuine care, especially its handful of serious entries. Most of the interactions tug on blood pressure itself, some deepening the drop until dizziness or fainting becomes a risk, others, tyramine among them, pushing pressure back up and undoing the medication's work. A few of the most serious act directly on heart rate, and activated charcoal can soak up the pill before your body absorbs it.
Potassium supplements matter here too, since valsartan makes it harder for the body to shed potassium, so levels can climb. Dozens of other herbs share the liver enzymes these drugs use, which could shift how much medication stays in your blood. Learn the five major-rated entries first; the rest of the 213 split into 173 moderate and 35 minor.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Nebivolol Hydrochloride, Valsartan: Top Interactions at a Glance
The most significant Nebivolol Hydrochloride, Valsartan supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 213 interacting ingredients — plus 1,239 more checked with no known interaction. See the complete ranked list.
The Major Interactions to Know About
The most clinically significant Nebivolol Hydrochloride, Valsartan + supplement combinations in our database, best-documented first. Open any card for the full report.
American hellebore can have potent cardiovascular effects due to the toxic steroid ester alkaloids it contains.
Read the full interaction Major Likelihood Likely Tyramine + Nebivolol Hydrochloride, ValsartaniTyramine may increase the risk of hypertension and reduce the effects of antihypertensive drugs.
Read the full interaction Major Likelihood Probable Activated Charcoal + Nebivolol Hydrochloride, ValsartaniActivated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full interaction Major Likelihood Probable American Mistletoe + Nebivolol Hydrochloride, ValsartaniAmerican mistletoe contains phoratoxin, a compound toxic to humans that induces smooth muscle contraction and vasoconstriction, potentially increasing blood pre...
Read the full interaction Major Likelihood Probable Indian Snakeroot + Nebivolol Hydrochloride, ValsartaniTheoretically, taking Indian snakeroot with beta-blockers might increase the risk of bradycardia and/or hypotension.
Read the full interactionEvery Supplement Checked Against Nebivolol Hydrochloride, Valsartan
All 1,452 ingredients in our database, ranked by severity — 213 with a Nebivolol Hydrochloride, Valsartan interaction on file and 1,239 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
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American HelleboreVeratrum Viride, american Veratrum, american White Hellebore, +11 more Likely
What it is: American Hellebore (Veratrum viride) is a highly poisonous plant whose root contains toxic alkaloids that can cause dangerous drops in heart...
American hellebore can have potent cardiovascular effects due to the toxic steroid ester alkaloids it contains.
Read the full American Hellebore + Nebivolol Hydrochloride, Valsartan interactionTyramine Likely
What it is: Tyramine is a natural compound formed when certain proteins break down, and it is found in aged cheeses, cured meats, fermented foods, and s...
Tyramine may increase the risk of hypertension and reduce the effects of antihypertensive drugs.
Read the full Tyramine + Nebivolol Hydrochloride, Valsartan interactionActivated CharcoalActivated Carbon, animal Charcoal, carbo Vegetabilis, +13 more Probable
What it is: Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some...
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Nebivolol Hydrochloride, Valsartan interactionAmerican MistletoePhoradendron Leucarpum, eastern Mistletoe Probable
What it is: American mistletoe is a parasitic plant that is best known as a holiday decoration, not a proven medicine.
American mistletoe contains phoratoxin, a compound toxic to humans that induces smooth muscle contraction and vasoconstriction, potentially increasing blood pressure and heart rate.
Read the full American Mistletoe + Nebivolol Hydrochloride, Valsartan interactionIndian SnakerootRauvolfia Serpentina, ajmaline, alseroxylon, +16 more Probable
What it is: Indian snakeroot is a traditional Ayurvedic plant that contains reserpine, a compound with real blood-pressure-lowering and sedative effects...
Theoretically, taking Indian snakeroot with beta-blockers might increase the risk of bradycardia and/or hypotension.
Read the full Indian Snakeroot + Nebivolol Hydrochloride, Valsartan interactionPotassium Likely
What it is: Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough fro...
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Nebivolol Hydrochloride, Valsartan interactionAppleMalus Domestica, abilde, almindelig Aeble, +25 more Probable
What it is: Apples are a nutritious whole food that provides fiber, vitamins, and antioxidant plant compounds, and eating them regularly fits well into...
Consuming apple juice with antihypertensive drugs might interfere with blood pressure control.
Read the full Apple + Nebivolol Hydrochloride, Valsartan interactionAyahuascaAppane, ayahoasca, caapi, +19 more Probable
What it is: Ayahuasca is a powerful psychoactive brew that combines a DMT-containing plant with a vine that allows the DMT to take effect, causing inten...
Theoretically, ayahuasca might increase plasma concentrations of CYP2D6 substrates.
Read the full Ayahuasca + Nebivolol Hydrochloride, Valsartan interactionBanabaLagerstroemia Speciosa, banaba Extract, banabalean, +8 more Probable
What it is: Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic...
Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Read the full Banaba + Nebivolol Hydrochloride, Valsartan interactionBeer Probable
What it is: Beer is an alcoholic beverage that contains some minerals, B vitamins, and plant compounds from hops and grain, but it is not a health suppl...
Theoretically, concomitant use may interfere with blood pressure control.
Read the full Beer + Nebivolol Hydrochloride, Valsartan interactionCannabidiol (cbd) Probable
What it is: CBD is a compound from the cannabis (hemp) plant that does not cause a 'high.' It has strong evidence only for certain rare seizure disorder...
Cannabidiol may increase levels of drugs metabolized by CYP2C9.
Read the full Cannabidiol (cbd) + Nebivolol Hydrochloride, Valsartan interactionCasein Peptides Probable
What it is: Casein peptides are small protein fragments made from milk casein, often studied for mild blood pressure support and relaxation.
Theoretically, combining these casein peptides with antihypertensive drugs might increase the risk of hypotension.
Read the full Casein Peptides + Nebivolol Hydrochloride, Valsartan interactionCat's ClawGriffe Du Chat, hawk's Claw, liane Du Pérou, +4 more Probable
What it is: Cat's claw is a South American vine traditionally used for inflammation, joint pain, and immune support.
Theoretically, taking cat's claw with antihypertensive drugs might increase the risk of hypotension.
Read the full Cat's Claw + Nebivolol Hydrochloride, Valsartan interactionCeleryApium Graveolens, ache Des Marais, ajamoda, +13 more Probable
What it is: Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint d...
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Nebivolol Hydrochloride, Valsartan interactionCocaErythroxylum Coca, bolivian Coca, coca De Java, +11 more Probable
What it is: Coca is a South American plant best known as the natural source of cocaine.
Theoretically, coca might reduce the effects of antihypertensive drugs.
Read the full Coca + Nebivolol Hydrochloride, Valsartan interactionCod Liver Oil Probable
What it is: Cod liver oil supplies omega-3 fatty acids (EPA and DHA) along with vitamins A and D, and is popular for heart, joint, and general health su...
Theoretically, taking cod liver oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Cod Liver Oil + Nebivolol Hydrochloride, Valsartan interactionCoffee CharcoalCafé Arabica, café Carbonisé, café Robusta, +5 more Probable
What it is: Coffee charcoal is made by roasting green coffee beans until they turn black, creating a charcoal-like material used traditionally for diarr...
Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two hours.
Read the full Coffee Charcoal + Nebivolol Hydrochloride, Valsartan interactionDocosahexaenoic Acid (dha)Adh, dha, fish Oil Fatty Acid, +7 more Probable
What it is: DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes.
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Docosahexaenoic Acid (dha) + Nebivolol Hydrochloride, Valsartan interactionEicosapentaenoic Acid (epa) Probable
What it is: EPA is an omega-3 fatty acid found mostly in fatty fish and fish oil, and it is best known for lowering high triglycerides.
Theoretically, taking EPA with antihypertensive drugs might increase the risk of hypotension.
Read the full Eicosapentaenoic Acid (epa) + Nebivolol Hydrochloride, Valsartan interactionEuropean MandrakeMandragora Officinarum, alraunwurzel, mandragora, +7 more Probable
What it is: European mandrake is a highly toxic plant from the nightshade family that was used in ancient and medieval times as a sedative and pain reli...
Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European mandrake.
Read the full European Mandrake + Nebivolol Hydrochloride, Valsartan interactionFever BarkAlstonia Constricta, alstonia Bark, australian Febrifuge, +10 more Probable
What it is: Fever bark is the bark of the Australian tree Alstonia constricta, used in traditional medicine for fever, diarrhea, and infections.
Theoretically, fever bark might alter the effects of antihypertensive drugs.
Read the full Fever Bark + Nebivolol Hydrochloride, Valsartan interactionFish Oil Probable
What it is: Fish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels.
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Nebivolol Hydrochloride, Valsartan interactionGlucomannanGlucomanano, glucomannane, konjac, +1 more Probable
What it is: Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipati...
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Nebivolol Hydrochloride, Valsartan interactionGoldensealHydrastis Canadensis, chinese Goldenseal, eye Balm, +14 more Probable
What it is: Goldenseal is a popular North American herb that contains berberine, a compound studied for antimicrobial effects.
Goldenseal might increase serum levels of drugs metabolized by CYP2D6.
Read the full Goldenseal + Nebivolol Hydrochloride, Valsartan interactionJapanese Persimmon Probable
What it is: Japanese persimmon is a nutritious fruit rich in fiber, vitamins, and antioxidant plant compounds, and its leaves and calyx are used in trad...
Japanese persimmon is thought to have hypotensive effects.
Read the full Japanese Persimmon + Nebivolol Hydrochloride, Valsartan interactionJava Tea Probable
What it is: Java Tea is a Southeast Asian herb traditionally used as a gentle diuretic and for urinary tract and kidney support.
Some preliminary clinical evidence suggests that Java tea has antihypertensive effects.
Read the full Java Tea + Nebivolol Hydrochloride, Valsartan interactionL-arginine2-amino-5-guanidinopentanoic Acid Probable
What it is: L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen.
Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
Read the full L-arginine + Nebivolol Hydrochloride, Valsartan interactionOctacosanol Probable
What it is: Octacosanol is a waxy long-chain alcohol from plant sources that is most often promoted for exercise endurance and cholesterol support, but...
Theoretically, concomitant use of octacosanol with beta-blockers might result in additive hypotensive effects.
Read the full Octacosanol + Nebivolol Hydrochloride, Valsartan interactionOlive Oil Probable
What it is: Olive oil, especially extra virgin olive oil, is a healthy fat that forms a cornerstone of the Mediterranean diet and is linked with better...
Theoretically, taking olive oil with antihypertensive drugs might have additive effects on blood pressure.
Read the full Olive Oil + Nebivolol Hydrochloride, Valsartan interactionPeriwinkle Probable
What it is: Periwinkle (Vinca minor) is a flowering plant whose alkaloids are the source of vinpocetine, a compound marketed for memory and brain circul...
Theoretically, taking periwinkle may increase the effects of antihypertensive drugs due to the hypotensive activity of vincamine, a constituent of periwinkle.
Read the full Periwinkle + Nebivolol Hydrochloride, Valsartan interactionPolicosanol32c, dotriacontanol, heptacosanol, +8 more Probable
What it is: Policosanol is a mix of waxy alcohols (mostly octacosanol) made from sugar cane or other plant waxes, and it is often marketed as a natural...
Concomitant use of policosanol with beta-blockers can cause additive blood pressure-lowering effects.
Read the full Policosanol + Nebivolol Hydrochloride, Valsartan interactionSesame Probable
What it is: Sesame is a nutritious seed and oil widely used in cooking and traditional medicine, and it provides healthy fats, fiber, and antioxidant co...
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame + Nebivolol Hydrochloride, Valsartan interactionSodium Probable
What it is: Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work.
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Nebivolol Hydrochloride, Valsartan interactionSyrian Rue Probable
What it is: Syrian Rue (Peganum harmala) is a traditional plant whose seeds contain potent compounds called harmala alkaloids, including MAO-inhibiting...
Theoretically, Syrian rue might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Syrian Rue + Nebivolol Hydrochloride, Valsartan interactionTaurine Probable
What it is: Taurine is an amino acid your body makes naturally and that you also get from animal foods.
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Taurine + Nebivolol Hydrochloride, Valsartan interactionWild CarrotDaucus Carota, beesnest Plant, bird's Nest Root, +10 more Probable
What it is: Wild carrot is a traditional herb (the wild ancestor of the garden carrot) used mostly for urinary, digestive, and menstrual complaints.
Theoretically, excessive doses of wild carrot seed oil might interfere with antihypertensive therapy due to cardiotonic effects.
Read the full Wild Carrot + Nebivolol Hydrochloride, Valsartan interactionWine Probable
What it is: Wine is an alcoholic beverage made from fermented grapes and is not a true dietary supplement or medicine.
Theoretically, concomitant use may interfere with blood pressure control.
Read the full Wine + Nebivolol Hydrochloride, Valsartan interactionYohimbePausinystalia Yohimbe, 11-hydroxy Yohimbine, coryanthe Yohimbe, +7 more Probable
What it is: Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac.
Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Read the full Yohimbe + Nebivolol Hydrochloride, Valsartan interaction1,3-dmaaDmaa, dimethylamylamine Possible
What it is: DMAA (1,3-dimethylamylamine) is a synthetic stimulant that was sold in pre-workout and weight-loss supplements but has been linked to seriou...
1,3-DMAA strongly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.
Read the full 1,3-dmaa + Nebivolol Hydrochloride, Valsartan interactionAcacia RigidulaVachellia Rigidula, acacia Rigidula, acaciopsis Rigidula, +3 more Possible
What it is: Acacia rigidula is a shrub from Texas and Mexico that is marketed in weight-loss and energy supplements.
Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP2D6 substrates.
Read the full Acacia Rigidula + Nebivolol Hydrochloride, Valsartan interactionActive Hexose Correlated Compound (ahcc) Possible
What it is: AHCC is a proprietary mushroom-derived supplement promoted mainly for immune support and to help people tolerate cancer treatment.
Theoretically, AHCC might increase levels of drugs metabolized by CYP2D6.
Read the full Active Hexose Correlated Compound (ahcc) + Nebivolol Hydrochloride, Valsartan interactionAdrafinilAdrafinilum, benzhydryl Sulfinyl Acetyl Hydroxamic Acid, crl-40028, +1 more Possible
What it is: Adrafinil is a synthetic compound that the body converts into modafinil, a prescription wakefulness-promoting drug.
Theoretically, adrafinil might reduce the effects of antihypertensive drugs.
Read the full Adrafinil + Nebivolol Hydrochloride, Valsartan interactionAfrican Wild Potato Possible
What it is: African Wild Potato (Hypoxis hemerocallidea) is a southern African plant traditionally used as a tonic and for immune, prostate, and inflamm...
In vitro research shows that African wild potato extract inhibits cytochrome P450 2C9 (CYP2C9).
Read the full African Wild Potato + Nebivolol Hydrochloride, Valsartan interactionAgmatineAgmatin, agmatine Sulfate, decarboxylated Arginine Possible
What it is: Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement.
Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Agmatine + Nebivolol Hydrochloride, Valsartan interactionAlgal OilDha-s Oil, dha-t Oil, dhasco Oil, +7 more Possible
What it is: Algal oil is a plant-based source of the omega-3 fats DHA and (in some products) EPA, making it a popular alternative to fish oil for vegeta...
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Nebivolol Hydrochloride, Valsartan interactionAndrographisAndrographis Paniculata, bhunimba, bidara, +19 more Possible
What it is: Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms an...
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis + Nebivolol Hydrochloride, Valsartan interactionArtichokeCynara Cardunculus, alcachofa, alcaucil, +17 more Possible
What it is: Artichoke leaf extract is a generally well-tolerated supplement that may have a mild cholesterol-lowering effect and is often used for indig...
Theoretically, artichoke leaf extract may increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Artichoke + Nebivolol Hydrochloride, Valsartan interactionAsafoetidaFerula Assa-foetida, a Wei, asafétida, +13 more Possible
What it is: Asafoetida is a strong-smelling plant resin used widely as a spice and in traditional medicine, mainly for digestive complaints.
Evidence from animal research suggests that asafoetida has hypotensive effects.
Read the full Asafoetida + Nebivolol Hydrochloride, Valsartan interactionAshFraxinus Americana, fraxinus Excelsior, bird's Tongue, +15 more Possible
What it is: Ash (Fraxinus excelsior and related species) is a tree whose leaves, bark, and seeds have a long history in folk medicine for arthritis, fev...
Theoretically, concomitant use of ash seed with antihypertensive drugs might have additive blood pressure lowering effects.
Read the full Ash + Nebivolol Hydrochloride, Valsartan interactionAshwagandhaWithania Somnifera, ajagandha, amangura, +17 more Possible
What it is: Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, thoug...
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha + Nebivolol Hydrochloride, Valsartan interactionBacopaBacopa Monnieri, andri, brahmi, +11 more Possible
What it is: Bacopa is an Ayurvedic herb most often used for memory and thinking.
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Bacopa + Nebivolol Hydrochloride, Valsartan interactionBaikal SkullcapScutellaria Baicalensis, baikal Scullcap, baikal Skullcap Root, +16 more Possible
What it is: Baikal skullcap is a traditional Chinese herb (Huang Qin) used for inflammation, allergies, and infections, with active compounds like baica...
Theoretically, concomitant use of Baikal skullcap with antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Baikal Skullcap + Nebivolol Hydrochloride, Valsartan interactionBasilOcimum Basilicum, albahaca, basilic, +15 more Possible
What it is: Basil is a popular cooking herb that is generally safe in the amounts used in food.
Theoretically, basil might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Basil + Nebivolol Hydrochloride, Valsartan interactionBerberineAlcaloïde De Berbérine, berberina, berbérine, +5 more Possible
What it is: Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of res...
Theoretically, berberine might have additive effects with antihypertensive drugs.
Read the full Berberine + Nebivolol Hydrochloride, Valsartan interactionBeta-glucans Possible
What it is: Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast.
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucans + Nebivolol Hydrochloride, Valsartan interactionBeta-methylphenethylamine (bmpea) Possible
What it is: Beta-methylphenethylamine (BMPEA) is a synthetic stimulant chemically similar to amphetamine that has been found in some weight-loss and spo...
Theoretically, BMPEA might increase the levels and clinical effects of CYP2D6 substrates.
Read the full Beta-methylphenethylamine (bmpea) + Nebivolol Hydrochloride, Valsartan interactionBetony Possible
What it is: Betony (Stachys officinalis) is a traditional European herb long used for headaches, nervous tension, and digestive complaints.
Theoretically, betony might have additive effects with blood pressure lowering drugs due to hypotensive activity of the glycosides found in betony.
Read the full Betony + Nebivolol Hydrochloride, Valsartan interactionBiofeedback Possible
What it is: Biofeedback is a mind-body technique, not an herb or supplement.
There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.
Read the full Biofeedback + Nebivolol Hydrochloride, Valsartan interactionBlack CohoshActaea Racemosa, baie D'actée, baneberry, +10 more Possible
What it is: Black cohosh is a North American plant most often used to ease menopause symptoms like hot flashes, but the research is mixed and far from s...
Some research suggests that black cohosh might inhibit CYP2D6, but there is conflicting evidence.
Read the full Black Cohosh + Nebivolol Hydrochloride, Valsartan interactionBlack PepperPiper Nigrum, black Peppercorn, extrait De Poivre, +23 more Possible
What it is: Black pepper is a common kitchen spice that is generally safe in the amounts used in food.
Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
Read the full Black Pepper + Nebivolol Hydrochloride, Valsartan interactionBlack SeedNigella Sativa, black Caraway, black Cumin, +18 more Possible
What it is: Black seed (Nigella sativa) is a traditional spice and remedy that has been studied for asthma, blood sugar, cholesterol, and blood pressure...
Theoretically, taking black seed with antihypertensive drugs might increase the risk of hypotension.
Read the full Black Seed + Nebivolol Hydrochloride, Valsartan interactionBlue Cohosh Possible
What it is: Blue cohosh is a traditional herb historically used by Native Americans and midwives to bring on labor or menstruation, but it carries serio...
Constituents in blue cohosh might increase blood pressure by causing coronary vasoconstriction.
Read the full Blue Cohosh + Nebivolol Hydrochloride, Valsartan interactionBoswellia SerrataBoswellia Serrata, arbre à Oliban Indien, boswella, +10 more Possible
What it is: Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation.
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Boswellia Serrata + Nebivolol Hydrochloride, Valsartan interactionBreadfruit Possible
What it is: Breadfruit is a starchy tropical fruit eaten as a staple food, and its leaves are used in traditional medicine for conditions like high bloo...
Theoretically, concomitant use with antihypertensive drugs might increase the risk of hypotension.
Read the full Breadfruit + Nebivolol Hydrochloride, Valsartan interactionBridelia Possible
What it is: Bridelia is a group of tropical plants, with Bridelia ferruginea widely used in traditional African medicine for diabetes, infections, and d...
Animal research suggests that Bridelia extracts decrease arterial pressure.
Read the full Bridelia + Nebivolol Hydrochloride, Valsartan interactionBulbine Natalensis Possible
What it is: Bulbine natalensis is a South African plant marketed mainly as a testosterone-boosting and libido supplement, but the human evidence is esse...
Theoretically, Bulbine natalensis stem might reduce the levels and clinical effects of CYP2C9 substrates.
Read the full Bulbine Natalensis + Nebivolol Hydrochloride, Valsartan interactionCajeput OilMelaleuca Leucadendra, aceite De Cajeput, cajeputi Aetheroleum, +10 more Possible
What it is: Cajeput oil is an aromatic essential oil traditionally used for aches, congestion, and minor skin complaints, but solid human evidence for t...
Evidence from in vitro research suggests that cajeput leaf extract can inhibit cytochrome P450 2D6 (CYP2D6) by approximately 30%.
Read the full Cajeput Oil + Nebivolol Hydrochloride, Valsartan interactionCalamusAcorus Calamus, acore Calame, acore Odorant, +20 more Possible
What it is: Calamus is a swamp plant with a long history in Ayurvedic and traditional Chinese medicine, mostly for digestive and nervous-system complain...
Theoretically, taking calamus with other antihypertensive medications might increase the risk of hypotension.
Read the full Calamus + Nebivolol Hydrochloride, Valsartan interactionCannabigerol (cbg) Possible
What it is: Cannabigerol (CBG) is a minor cannabinoid from the cannabis (hemp) plant that is marketed for anxiety, pain, and inflammation, but human res...
Theoretically, taking cannabigerol with antihypertensive drugs might increase the risk of hypotension.
Read the full Cannabigerol (cbg) + Nebivolol Hydrochloride, Valsartan interactionCannabinol (cbn) Possible
What it is: Cannabinol (CBN) is a minor cannabinoid found in the cannabis plant, often marketed as a 'sleep' aid, but solid human research is very limit...
Theoretically, cannabinol might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Cannabinol (cbn) + Nebivolol Hydrochloride, Valsartan interactionCannabisCannabis Sativa, anashca, banji, +25 more Possible
What it is: Cannabis contains many active compounds, mainly THC (which causes a 'high') and CBD (which does not).
Theoretically, cannabis might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cannabis + Nebivolol Hydrochloride, Valsartan interactionCaprylic AcidOctanoic Acid Possible
What it is: Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut heal...
Theoretically, caprylic acid might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Caprylic Acid + Nebivolol Hydrochloride, Valsartan interactionCatechuBlack Catechu, acacia Catechu: Acacia à Cachou, acacia Catechu Heartwood Extract, +17 more Possible
What it is: Catechu is an astringent extract made from the heartwood of the Acacia (Senegalia) catechu tree, used traditionally for mouth sores, sore th...
Theoretically, concomitant use with antihypertensive drugs might increase the risk of hypotension.
Read the full Catechu + Nebivolol Hydrochloride, Valsartan interactionCeylon CinnamonCinnamomum Verum, batavia Cassia, batavia Cinnamon, +13 more Possible
What it is: Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and diges...
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Nebivolol Hydrochloride, Valsartan interactionCeylon Leadwort Possible
What it is: Ceylon Leadwort (Plumbago zeylanica) is a plant long used in Ayurvedic and other traditional medicine systems, mainly for digestion, skin pr...
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro.
Read the full Ceylon Leadwort + Nebivolol Hydrochloride, Valsartan interactionCinchonaCinchona Calisaya, arbol De La Quina, bois Aux Fièvres, +14 more Possible
What it is: Cinchona bark is the natural source of quinine and has been used for centuries to treat malaria and fever, but the bark itself is not standa...
Theoretically, taking cinchona might inhibit cytochrome P450 2D6 (CYP2D6) and increase levels of drugs metabolized by this enzyme.
Read the full Cinchona + Nebivolol Hydrochloride, Valsartan interactionCloveSyzygium Aromaticum, bourgeon Floral De Clou De Girofle, bouton Floral De Clou De Girofle, +12 more Possible
What it is: Clove is a common cooking spice that is also used in traditional medicine, especially as a topical numbing agent for tooth pain thanks to it...
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Nebivolol Hydrochloride, Valsartan interactionCocoaTheobroma Cacao, chocolat, chocolat Noir, +14 more Possible
What it is: Cocoa is rich in plant compounds called flavanols that may modestly support blood vessel function and blood pressure, but most chocolate pro...
Theoretically, taking cocoa with antihypertensive drugs might increase the risk of hypotension.
Read the full Cocoa + Nebivolol Hydrochloride, Valsartan interactionCoconut WaterCocos Nucifera Possible
What it is: Coconut water is a natural drink rich in potassium and other electrolytes that many people use for hydration, especially around exercise.
Theoretically, taking coconut water with antihypertensive drugs might increase the risk of hypotension.
Read the full Coconut Water + Nebivolol Hydrochloride, Valsartan interactionColeus6beta, 17beta-acetoxy-8, 13-epoxy-1alpha, +15 more Possible
What it is: Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart he...
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Nebivolol Hydrochloride, Valsartan interactionColtsfootTussilago Farfara, ass's Foot, brandlattich, +17 more Possible
What it is: Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking.
Theoretically, excessive doses of coltsfoot may interfere with antihypertensive or cardiovascular therapy.
Read the full Coltsfoot + Nebivolol Hydrochloride, Valsartan interactionCombretum MicranthumAntidote à L'opium, antidote D'opium, antídoto De Opio, +8 more Possible
What it is: Combretum micranthum (kinkeliba) is a West African shrub whose leaves are brewed into a traditional tea for digestion, liver complaints, and...
Theoretically, taking Combretum micranthum leaf with antihypertensive drugs might increase the risk of hypotension.
Read the full Combretum Micranthum + Nebivolol Hydrochloride, Valsartan interactionConjugated Linoleic Acid (cla) Possible
What it is: CLA is a fatty acid found naturally in meat and dairy, and supplements are usually made from safflower oil.
Theoretically, taking CLA with antihypertensive drugs might increase the risk of hypotension.
Read the full Conjugated Linoleic Acid (cla) + Nebivolol Hydrochloride, Valsartan interactionCorianderCoriandrum Sativum, coriander Essential Oil, coriandre, +5 more Possible
What it is: Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints...
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Coriander + Nebivolol Hydrochloride, Valsartan interactionCorn SilkZea Mays, barbe De Maïs, blé D'inde, +13 more Possible
What it is: Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints.
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk + Nebivolol Hydrochloride, Valsartan interactionCorydalis Yanhusuo Possible
What it is: Corydalis yanhusuo is a traditional Chinese herb used mainly for pain.
Theoretically, Corydalis yanhusuo might have additive effects with antihypertensive drugs.
Read the full Corydalis Yanhusuo + Nebivolol Hydrochloride, Valsartan interactionDanshenSalvia Bowleyana, ch'ih Shen, chinese Red Sage, +15 more Possible
What it is: Danshen is a root used in traditional Chinese medicine, mainly for heart and circulation problems.
Theoretically, taking danshen with antihypertensive drugs might increase the risk of hypotension.
Read the full Danshen + Nebivolol Hydrochloride, Valsartan interactionDendrobium Possible
What it is: Dendrobium is a group of orchids long used in traditional Chinese medicine, often to moisten the body and as a general tonic.
The dendrobium constituent dendrobine is reported to have convulsant effects.
Read the full Dendrobium + Nebivolol Hydrochloride, Valsartan interactionDevil's ClawHarpagophytum Procumbens, devils Claw, devil's Claw Root, +9 more Possible
What it is: Devil's claw is a southern African plant used mainly for arthritis and back pain, and some studies suggest it may help ease these types of d...
Theoretically, devil's claw might increase levels of drugs metabolized by CYP2C9.
Read the full Devil's Claw + Nebivolol Hydrochloride, Valsartan interactionDiosmin Possible
What it is: Diosmin is a citrus-derived flavonoid most often used for vein-related problems such as chronic venous insufficiency and hemorrhoids, and it...
Theoretically, diosmin might inhibit the metabolism of CYP2C9 substrates.
Read the full Diosmin + Nebivolol Hydrochloride, Valsartan interactionEleutheroEleutherococcus Senticosus, acanthopanax Obovatus, ciwujia Root, +13 more Possible
What it is: Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress.
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
Read the full Eleuthero + Nebivolol Hydrochloride, Valsartan interactionEnglish IvyHedera Helix, common Ivy, gum Ivy, +9 more Possible
What it is: English ivy leaf extract is most commonly used in cough and cold syrups to help loosen mucus and ease coughing, and it is a popular ingredie...
Theoretically, English ivy might increase the levels of drugs metabolized by CYP2D6.
Read the full English Ivy + Nebivolol Hydrochloride, Valsartan interactionEucalyptusEucalyptus Globulus, blue Gum, blue Mallee, +13 more Possible
What it is: Eucalyptus is best known for its strong-smelling oil used in vapor rubs, inhalants, and lozenges to ease coughs and congestion.
Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
Read the full Eucalyptus + Nebivolol Hydrochloride, Valsartan interactionEuropean BarberryBerberis Vulgaris, agracejo, barberry, +15 more Possible
What it is: European barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolat...
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full European Barberry + Nebivolol Hydrochloride, Valsartan interactionEuropean MistletoeViscum Album, all-heal, banda, +23 more Possible
What it is: European mistletoe is a parasitic plant most studied as an injectable extract used alongside conventional cancer care in some European count...
Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full European Mistletoe + Nebivolol Hydrochloride, Valsartan interactionFalse UnicornChamaelirium Luteum, alétris, blazing Star, +9 more Possible
What it is: False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concern...
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Nebivolol Hydrochloride, Valsartan interactionFermented Milk Possible
What it is: Fermented milk is a food made by culturing milk with helpful bacteria or yeast, and it provides protein, calcium, and probiotics.
Theoretically, fermented milk might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Fermented Milk + Nebivolol Hydrochloride, Valsartan interactionFeverfewTanacetum Parthenium, altamisa, bachelor's Buttons, +13 more Possible
What it is: Feverfew is a daisy-family herb best known for migraine prevention, where some studies suggest it may modestly lower how often migraines occ...
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew + Nebivolol Hydrochloride, Valsartan interactionFlaxseedLinum Usitatissimum, alasi, aliviraaii, +20 more Possible
What it is: Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans.
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Nebivolol Hydrochloride, Valsartan interactionFlaxseed Oil Possible
What it is: Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil.
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Nebivolol Hydrochloride, Valsartan interactionFo-ti Possible
What it is: Fo-ti (He Shou Wu) is a root used in traditional Chinese medicine, often promoted for healthy aging and hair.
Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Fo-ti + Nebivolol Hydrochloride, Valsartan interactionGamma-aminobutyric Acid (gaba)Acide Bêta-phényl-gamma-amino-butyrique, acide Gamma-aminobutyrique, Ácido Gama-aminobutríco, +3 more Possible
What it is: GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety,...
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid (gaba) + Nebivolol Hydrochloride, Valsartan interactionGarden CressLepidium Sativum, berro Hortelano, cresson Alénois, +3 more Possible
What it is: Garden cress is a nutritious leafy herb and seed used widely in cooking and traditional medicine, providing vitamins, minerals, and fiber.
Theoretically, taking garden cress with antihypertensive drugs might increase the risk of hypotension.
Read the full Garden Cress + Nebivolol Hydrochloride, Valsartan interactionGarlicAllium Sativum, aged Black Garlic Extract, aged Garlic Extract, +16 more Possible
What it is: Garlic is a common food and supplement that may modestly help with blood pressure and cholesterol, though the evidence is mixed and effects...
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
Read the full Garlic + Nebivolol Hydrochloride, Valsartan interactionGentian Possible
What it is: Gentian is a very bitter root traditionally used to stimulate appetite and ease mild digestive complaints, often as part of "bitters" before...
Theoretically, taking gentian with antihypertensive drugs might increase the risk of hypotension.
Read the full Gentian + Nebivolol Hydrochloride, Valsartan interactionGerman ChamomileMatricaria Recutita, blue Chamomile, camomèle, +12 more Possible
What it is: German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints.
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile + Nebivolol Hydrochloride, Valsartan interactionGinkgoGinkgo Biloba, abricot Argenté Japonais, adiantifolia, +13 more Possible
What it is: Ginkgo is one of the world's most popular herbal supplements, mostly taken to support memory and circulation.
Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.
Read the full Ginkgo + Nebivolol Hydrochloride, Valsartan interactionGojiLycium Chinense, lycium Barbarum, barberry Matrimony Vine, +15 more Possible
What it is: Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food.
Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Read the full Goji + Nebivolol Hydrochloride, Valsartan interactionGrapeVitis Vinifera, activin, black Grape Raisins, +10 more Possible
What it is: Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support h...
Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
Read the full Grape + Nebivolol Hydrochloride, Valsartan interactionGrapefruitCitrus Paradisi Possible
What it is: Grapefruit is a nutritious citrus fruit rich in vitamin C and other nutrients, and it is generally safe to eat.
Theoretically, grapefruit juice might increase levels of drugs metabolized by CYP2C9.
Read the full Grapefruit + Nebivolol Hydrochloride, Valsartan interactionGreater CelandineChelidonium Majus, bai Qu Cai, celandine, +9 more Possible
What it is: Greater celandine is a traditional herb most often promoted for digestive and gallbladder complaints, but solid human evidence for any use i...
Research in vitro shows that chelidonine, a constituent of greater celandine, inhibits cytochrome P450 2D6 (CYP2D6) enzyme activity.
Read the full Greater Celandine + Nebivolol Hydrochloride, Valsartan interactionGuar GumDietary Fiber, farine De Guar, fibre Alimentaire, +10 more Possible
What it is: Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity.
Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Read the full Guar Gum + Nebivolol Hydrochloride, Valsartan interactionGuarumoCecropia Obtusifolia, chancarro, grayumbo, +9 more Possible
What it is: Guarumo (Cecropia obtusifolia) is a tropical tree used in Latin American traditional medicine, most often as a leaf tea for diabetes and hig...
Evidence from animal research suggests that aqueous and ethanolic extracts of guarumo leaf can lower blood pressure when administered intravenously to rats.
Read the full Guarumo + Nebivolol Hydrochloride, Valsartan interactionGum ArabicAcacia, acacia Gum, arabic Gum, +16 more Possible
What it is: Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplemen...
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Gum Arabic + Nebivolol Hydrochloride, Valsartan interactionGymnemaGymnema Sylvestre, gimnema, gur-mar, +14 more Possible
What it is: Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue.
Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Read the full Gymnema + Nebivolol Hydrochloride, Valsartan interactionHawthornAubepine, aubépine, aubépine Blanche, +15 more Possible
What it is: Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart fa...
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorn + Nebivolol Hydrochloride, Valsartan interactionHesperidinAlpha-glucosyl Hesperidin, alpha-glucosylhesperidin, bioflavonoid, +8 more Possible
What it is: Hesperidin is a flavonoid found in citrus fruits that is often combined with diosmin and used for vein and circulation problems like hemorrh...
Theoretically, taking hesperidin with antihypertensive drugs might increase the risk of hypotension.
Read the full Hesperidin + Nebivolol Hydrochloride, Valsartan interactionHibiscus SabdariffaHibiscus Sabdariffa, agua De Jamaica, ambashthaki, +16 more Possible
What it is: Hibiscus sabdariffa is a tart, cranberry-flavored plant most often consumed as a tea, and its best-studied use is for mildly lowering blood...
Theoretically, taking Hibiscus sabdariffa with antihypertensive drugs might increase the risk of hypotension.
Read the full Hibiscus Sabdariffa + Nebivolol Hydrochloride, Valsartan interactionHigenamine Possible
What it is: Higenamine is a plant-based stimulant compound added to many weight-loss and pre-workout supplements, but there is very little human evidenc...
Theoretically, higenamine might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Higenamine + Nebivolol Hydrochloride, Valsartan interactionHoodiaHoodia Gordonii, cactus, cactus Hoodia, +6 more Possible
What it is: Hoodia is a succulent plant from southern Africa that is marketed as an appetite suppressant for weight loss, but solid human evidence that...
Evidence from in vitro research shows that hoodia may stimulate beta-adrenergic receptors.
Read the full Hoodia + Nebivolol Hydrochloride, Valsartan interactionHorny Goat WeedEpimedium Grandiflorum, barrenwort, Épimède, +10 more Possible
What it is: Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence...
Theoretically, horny goat weed might increase the risk of hypotension.
Read the full Horny Goat Weed + Nebivolol Hydrochloride, Valsartan interactionIpriflavone7-isopropoxyisoflavone, ipriflavona Possible
What it is: Ipriflavone is a synthetic isoflavone studied mainly for bone health and osteoporosis, but high-quality research has not shown that it relia...
Ipriflavone is thought to competitively inhibit cytochrome P450 2C9 (CYP2C9).
Read the full Ipriflavone + Nebivolol Hydrochloride, Valsartan interactionIsopropylnorsynephrine Possible
What it is: Isopropylnorsynephrine is a synthetic stimulant chemically related to synephrine, marketed mainly in weight-loss and pre-workout supplements...
Theoretically, isopropylnorsynephrine might decrease the effects of antihypertensive drugs.
Read the full Isopropylnorsynephrine + Nebivolol Hydrochloride, Valsartan interactionJambolan Possible
What it is: Jambolan (Syzygium cumini), also called Java plum or black plum, is a tropical fruit tree traditionally used for blood sugar and digestive c...
There is some in vitro evidence that jambolan can inhibit CYP2C9.
Read the full Jambolan + Nebivolol Hydrochloride, Valsartan interactionKavaPiper Methysticum, ava Pepper, ava Root, +20 more Possible
What it is: Kava is a Pacific Island plant traditionally used to promote relaxation and ease anxiety, and some studies suggest it may help mild anxiety.
Theoretically, kava might increase levels of CYP2C9 substrates.
Read the full Kava + Nebivolol Hydrochloride, Valsartan interactionKhatCatha Edulis, abessinischer Tea, abyssinian Tea, +23 more Possible
What it is: Khat is a plant chewed for its amphetamine-like stimulant effects, but it carries serious risks including high blood pressure, heart problem...
Human research shows that khat and its constituent, cathinone, can increase blood pressure.
Read the full Khat + Nebivolol Hydrochloride, Valsartan interactionKiwi Possible
What it is: Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food.
Clinical research suggests that consuming kiwi reduces systolic and diastolic blood pressure in hypertensive individuals.
Read the full Kiwi + Nebivolol Hydrochloride, Valsartan interactionKorean Pine Possible
What it is: Korean Pine is best known as the source of edible pine nuts and pine nut oil, which are nutritious foods rich in healthy fats.
Animal research shows that Korean pine nut oil reduces blood pressure in spontaneously hypertensive rats.
Read the full Korean Pine + Nebivolol Hydrochloride, Valsartan interactionKratomMitragyna Speciosa, biak-biak, cratom, +16 more Possible
What it is: Kratom is a Southeast Asian plant whose leaves act on the brain's opioid receptors and can produce both stimulant-like and opioid-like effec...
Theoretically, kratom might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Kratom + Nebivolol Hydrochloride, Valsartan interactionL-citrulline Possible
What it is: L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blo...
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Nebivolol Hydrochloride, Valsartan interactionLentinanBeta-glucan Lentinan, lentinane, lentinus Edodes Polysaccharide, +4 more Possible
What it is: Lentinan is a beta-glucan polysaccharide from shiitake mushrooms that is studied mainly as an immune-modulating add-on to cancer chemotherap...
Laboratory research suggests that lentinan might increase the activity of cytochrome P450 2D6 (CYP2D6).
Read the full Lentinan + Nebivolol Hydrochloride, Valsartan interactionLicoriceGlycyrrhiza Echinate, alcacuz, bois Doux, +17 more Possible
What it is: Licorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most...
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Nebivolol Hydrochloride, Valsartan interactionLimonene Possible
What it is: Limonene is a natural compound found in the peel of citrus fruits like oranges and lemons, and it is used as a flavoring agent and dietary s...
There's preliminary evidence that limonene might be a substrate for cytochrome P450 2C9 (CYP2C9), as well causing its induction.
Read the full Limonene + Nebivolol Hydrochloride, Valsartan interactionMaitake MushroomGrifola Frondosa, champignon Dansant, champignon Des Fous Dansants, +13 more Possible
What it is: Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sug...
Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Maitake Mushroom + Nebivolol Hydrochloride, Valsartan interactionMalic Acid Possible
What it is: Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and mu...
Theoretically, malic acid might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Malic Acid + Nebivolol Hydrochloride, Valsartan interactionMelatoninN-acetyl-5-methoxytryptamine Possible
What it is: Melatonin is a hormone your body makes naturally to help control your sleep-wake cycle, and the supplement form is widely used to help with...
Theoretically, taking melatonin with antihypertensive drugs might increase the risk of hypotension or hypertension.
Read the full Melatonin + Nebivolol Hydrochloride, Valsartan interactionN,n-dmpea Possible
What it is: N,N-DMPEA (N,N-dimethylphenethylamine) is a synthetic relative of phenethylamine sometimes marketed in stimulant or pre-workout supplements.
In vitro research shows that N,N-DMPEA strongly inhibits cytochrome P450 2D6 (CYP2D6).
Read the full N,n-dmpea + Nebivolol Hydrochloride, Valsartan interactionN-acetyl Cysteine (nac)Acetyl Cysteine, mucomyst Possible
What it is: N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione.
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine (nac) + Nebivolol Hydrochloride, Valsartan interactionNattokinaseBsp, extrait De Natto, fermented Soybeans, +7 more Possible
What it is: Nattokinase is an enzyme from the fermented soybean food natto that may have mild blood-thinning and blood-flow effects.
Theoretically, nattokinase might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Nattokinase + Nebivolol Hydrochloride, Valsartan interactionNeemAzadirachta Indica, arishta, arishtha, +18 more Possible
What it is: Neem is a tree from India used for centuries in traditional medicine, especially for skin, dental, and antimicrobial purposes.
Theoretically, neem leaf extract might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Neem + Nebivolol Hydrochloride, Valsartan interactionNiacin3-pyridinecarboxylic Acid, vitamin B3 Possible
What it is: Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countri...
Theoretically, niacin may increase the risk of hypotension when used with antihypertensive drugs.
Read the full Niacin + Nebivolol Hydrochloride, Valsartan interactionNoniMorinda Citrifolia, ba Ji Tian, bois Douleur, +17 more Possible
What it is: Noni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claime...
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Nebivolol Hydrochloride, Valsartan interactionOctopamine Possible
What it is: Octopamine is a stimulant-like compound found in small amounts in some plants (such as bitter orange) and made naturally in the body.
In humans, octopamine 450-600 mg daily increases blood pressure in hypotensive patients.
Read the full Octopamine + Nebivolol Hydrochloride, Valsartan interactionOregon GrapeMahonia Aquifolium, barberry, berberis, +13 more Possible
What it is: Oregon grape is a shrub whose root contains berberine and related compounds.
Theoretically, Oregon grape might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Oregon Grape + Nebivolol Hydrochloride, Valsartan interactionPanax GinsengAsian Ginseng, asiatic Ginseng, chinese Ginseng, +12 more Possible
What it is: Panax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is m...
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Panax Ginseng + Nebivolol Hydrochloride, Valsartan interactionPeppermintMentha X Piperita, black Peppermint, brandy Mint, +12 more Possible
What it is: Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms.
Theoretically, peppermint might increase the levels of CYP2C9 substrates.
Read the full Peppermint + Nebivolol Hydrochloride, Valsartan interactionPhellodendronPhellodendron Amurense, amur Cork Bark, amur Cork Tree, +7 more Possible
What it is: Phellodendron is a traditional Chinese medicine bark (Huang Bai) that contains berberine and other plant compounds with antimicrobial and an...
Theoretically, phellodendron might have additive effects with antihypertensive drugs.
Read the full Phellodendron + Nebivolol Hydrochloride, Valsartan interactionPomegranatePunica Granatum, anardana, dadim, +14 more Possible
What it is: Pomegranate is a nutrient-rich fruit that is high in antioxidants and is widely enjoyed as food and juice.
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate + Nebivolol Hydrochloride, Valsartan interactionPropolisAcide De Cire D'abeille, baume De Propolis, bee Glue, +12 more Possible
What it is: Propolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies.
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
Read the full Propolis + Nebivolol Hydrochloride, Valsartan interactionPuravive Possible
What it is: Puravive is a branded, multi-ingredient capsule marketed mainly for weight loss by claiming to boost brown fat activity, but there is no pub...
Puravive contains quercetin, which has been shown in studies to mildly inhibit the CYP2C9 metabolizing enzyme.
Read the full Puravive + Nebivolol Hydrochloride, Valsartan interactionQuercetin7-pentahydroxyflavone, bioflavonoid, bioflavonoid Complex, +9 more Possible
What it is: Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties found in many common foods and sold as a supplement.
Theoretically, taking quercetin with antihypertensive drugs might increase the risk of hypotension.
Read the full Quercetin + Nebivolol Hydrochloride, Valsartan interactionRauvolfia Vomitoria Possible
What it is: Rauvolfia vomitoria is an African shrub whose root contains powerful alkaloids, including reserpine, that have historically been used for hi...
Theoretically, Rauvolfia vomitoria might increase the risk of hypotension.
Read the full Rauvolfia Vomitoria + Nebivolol Hydrochloride, Valsartan interactionRauwolscine Possible
What it is: Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout su...
Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.
Read the full Rauwolscine + Nebivolol Hydrochloride, Valsartan interactionRehmannia Possible
What it is: Rehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health.
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Rehmannia + Nebivolol Hydrochloride, Valsartan interactionReishi MushroomGanoderma Lucidum, basidiomycetes Mushroom, champignon Reishi, +15 more Possible
What it is: Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness.
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mushroom + Nebivolol Hydrochloride, Valsartan interactionRhodiolaRhodiola Rosea, arctic Root, golden Root, +12 more Possible
What it is: Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress.
Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
Read the full Rhodiola + Nebivolol Hydrochloride, Valsartan interactionRooibosAspalathus Linearis, green Red Bush, infusion Rooibos, +9 more Possible
What it is: Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage.
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Nebivolol Hydrochloride, Valsartan interactionRoyal JellyBee Saliva, bee Spit, gelée Royale, +4 more Possible
What it is: Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee.
Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Royal Jelly + Nebivolol Hydrochloride, Valsartan interactionSaffronCrocus Sativus, autumn Crocus, azafrán, +16 more Possible
What it is: Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most r...
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Read the full Saffron + Nebivolol Hydrochloride, Valsartan interactionSageSalvia Officinalis, broadleaf Sage, common Sage, +14 more Possible
What it is: Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and me...
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage + Nebivolol Hydrochloride, Valsartan interactionSchisandraSchisandra Chinensis, bac Ngu Vi Tu, baie De Schisandra, +10 more Possible
What it is: Schisandra is a traditional Chinese medicine berry used as an adaptogen for stress, fatigue, and liver support.
Theoretically, schisandra might decrease the levels and clinical effects of CYP2C9 substrates.
Read the full Schisandra + Nebivolol Hydrochloride, Valsartan interactionSchizonepeta Possible
What it is: Schizonepeta is a mint-family herb long used in traditional Chinese medicine, usually as part of combination formulas for colds, fevers, and...
Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2D6.
Read the full Schizonepeta + Nebivolol Hydrochloride, Valsartan interactionSea BuckthornAnanas De Sibérie, argasse, argousier, +17 more Possible
What it is: Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart he...
Theoretically, taking sea buckthorn with antihypertensive drugs might increase the risk of hypotension.
Read the full Sea Buckthorn + Nebivolol Hydrochloride, Valsartan interactionShiitake Mushroom Possible
What it is: Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people.
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Shiitake Mushroom + Nebivolol Hydrochloride, Valsartan interactionSlippery ElmIndian Elm, moose Elm, olmo Americano, +7 more Possible
What it is: Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and ir...
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Nebivolol Hydrochloride, Valsartan interactionSoy Possible
What it is: Soy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones.
Theoretically soy protein may have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Soy + Nebivolol Hydrochloride, Valsartan interactionSt. John's WortHypericum Perforatum, amber Touch-and-heal, barbe De Saint-jean, +13 more Possible
TerminaliaTerminalia Arjuna, abhaya, amandier Indien, +19 more Possible
What it is: Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness...
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia + Nebivolol Hydrochloride, Valsartan interactionTheanine Possible
What it is: Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without...
Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Read the full Theanine + Nebivolol Hydrochloride, Valsartan interactionThuja Possible
What it is: Thuja, also called northern white cedar or arborvitae, is a tree whose leaf and oil have a long history in folk and homeopathic medicine, es...
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Nebivolol Hydrochloride, Valsartan interactionTinospora Cordifolia Possible
What it is: Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat...
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Nebivolol Hydrochloride, Valsartan interactionTragacanthAdragante, astragale Adragant, astragale De Marseille, +14 more Possible
What it is: Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the thro...
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Tragacanth + Nebivolol Hydrochloride, Valsartan interactionTree Turmeric Possible
What it is: Tree turmeric (Berberis aristata) is a shrub used in traditional Indian (Ayurvedic) medicine, valued mainly for its berberine content.
Theoretically, taking tree turmeric along with antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Tree Turmeric + Nebivolol Hydrochloride, Valsartan interactionTribulusTribulus Terrestris, abrojo, abrojos, +17 more Possible
What it is: Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind th...
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Read the full Tribulus + Nebivolol Hydrochloride, Valsartan interactionVinpocetineEburnamenine-14-carboxylic Acid, ay-27255, cavinton, +11 more Possible
What it is: Vinpocetine is a lab-made compound based on a chemical from the periwinkle plant, and it is marketed mainly for memory and brain health.
Theoretically, vinpocetine might increase levels of drugs metabolized by CYP2C9.
Read the full Vinpocetine + Nebivolol Hydrochloride, Valsartan interactionVitamin B6 Possible
What it is: Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cell...
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Nebivolol Hydrochloride, Valsartan interactionWhite HorehoundMarrubium Vulgare, bonhomme, grand Bonhomme, +8 more Possible
What it is: White horehound is a traditional bitter herb used mainly for coughs, sore throats, and mild digestive complaints, and it is a common flavori...
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full White Horehound + Nebivolol Hydrochloride, Valsartan interactionWhite Pepper Possible
What it is: White pepper comes from the same plant as black pepper and is mostly used as a kitchen spice.
In vitro evidence suggests that some constituents of white pepper inhibit cytochrome P450 2D6 (CYP2D6).
Read the full White Pepper + Nebivolol Hydrochloride, Valsartan interactionThyroid Extract Likely
What it is: Thyroid extract supplements are made from dried animal thyroid gland and may contain real thyroid hormones (T3 and T4), but the amounts in o...
Food and medications can interfere with thyroid hormone absorption.
Read the full Thyroid Extract + Nebivolol Hydrochloride, Valsartan interaction1,3-dmba Possible
What it is: 1,3-DMBA is a synthetic stimulant chemically similar to the banned stimulant DMAA, and it is not a proven or safe dietary ingredient.
Theoretically, 1,3-DMBA might modestly increase the levels of CYP2D6 substrates.
Read the full 1,3-dmba + Nebivolol Hydrochloride, Valsartan interactionAgarAgar-agar, agarose, agarose Gel, +17 more Possible
What it is: Agar is a plant-based gel made from red seaweed that is widely used as a vegetarian alternative to gelatin and as a source of dietary fiber.
Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Read the full Agar + Nebivolol Hydrochloride, Valsartan interactionAlginAlginate, alginate De Calcium, alginate De Magnésium, +12 more Possible
What it is: Algin (alginate) is a fiber-like substance from brown seaweed that is widely used as a thickener, gel, and binder in foods and medicines.
Theoretically, algin can alter the absorption of oral drugs.
Read the full Algin + Nebivolol Hydrochloride, Valsartan interactionBeetBeta Vulgaris, beet Greens, beet Juice, +19 more Possible
What it is: Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in...
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Nebivolol Hydrochloride, Valsartan interactionBitter OrangeCitrus Aurantium, aurantii Fructus, aurantium, +17 more Possible
What it is: Bitter orange is a citrus fruit whose extracts contain synephrine, a mild stimulant often added to weight-loss and energy supplements.
Theoretically, bitter orange might increase levels of drug metabolized by CYP2D6.
Read the full Bitter Orange + Nebivolol Hydrochloride, Valsartan interactionBlack PsylliumAfrican Plantain, brown Psyllium, dietary Fiber, +16 more Possible
What it is: Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive...
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Black Psyllium + Nebivolol Hydrochloride, Valsartan interactionBlond PsylliumPlantago Ovata, balle De Psyllium, blond Plantago, +14 more Possible
What it is: Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements.
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Blond Psyllium + Nebivolol Hydrochloride, Valsartan interactionCarobCeratonia Siliqua, algarrobo, carob Flour, +16 more Possible
What it is: Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum...
Theoretically, carob might also impair the absorption of oral drugs.
Read the full Carob + Nebivolol Hydrochloride, Valsartan interactionCoenzyme Q10Coq10 Possible
What it is: CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant.
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Nebivolol Hydrochloride, Valsartan interactionDulsePalmaria Palmata, rhodymenia Palmata Possible
What it is: Dulse is a red seaweed eaten as a food in many coastal cultures and is a natural source of iodine, potassium, protein, and antioxidant compo...
Theoretically, dulse might increase the risk of hyperkalemia when taken with ARBs.
Read the full Dulse + Nebivolol Hydrochloride, Valsartan interactionEvening PrimroseOenothera Biennis, oenothera Muricata, oenothera Rubricaulis, +3 more Possible
What it is: Evening primrose oil is a seed oil rich in gamma-linolenic acid (GLA), an omega-6 fatty acid, that is popularly used for skin conditions, PM...
Theoretically, evening primrose may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Evening Primrose + Nebivolol Hydrochloride, Valsartan interactionFenugreekTrigonella Foenum-graecum, alholva, bird's Foot, +14 more Possible
What it is: Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk prod...
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek + Nebivolol Hydrochloride, Valsartan interactionFucus VesiculosusBlack Tang, bladder Fucus, bladder Wrack, +14 more Possible
What it is: Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin.
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Fucus Vesiculosus + Nebivolol Hydrochloride, Valsartan interactionGenistein Combined Polysaccharide Possible
What it is: Genistein Combined Polysaccharide (GCP) is a soy-and-mushroom supplement studied mostly for hormone-related cancers like prostate cancer, bu...
Some evidence suggests that genistein can alter the pharmacokinetics of CYP2C9 substrates and should be used cautiously with them.
Read the full Genistein Combined Polysaccharide + Nebivolol Hydrochloride, Valsartan interactionGingerZingiber Officinale, african Ginger, ardraka, +21 more Possible
What it is: Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nause...
Theoretically, ginger might increase the levels of CYP2C9 substrates.
Read the full Ginger + Nebivolol Hydrochloride, Valsartan interactionGreen CoffeeCoffea Arabica, coffea Canephora, coffea Bukobensis, +2 more Possible
What it is: Green coffee is the unroasted bean of the coffee plant, prized for its high chlorogenic acid content.
Theoretically, taking green coffee with antihypertensive drugs might increase the risk of hypotension.
Read the full Green Coffee + Nebivolol Hydrochloride, Valsartan interactionHordenineAnhalinine Possible
What it is: Hordenine is a natural alkaloid found in barley and some cacti that is marketed as a stimulant for energy, focus, and fat loss, but solid hu...
Hordenine weakly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.
Read the full Hordenine + Nebivolol Hydrochloride, Valsartan interactionHumann Superbeets Heart Chews Possible
What it is: SuperBeets Heart Chews are a beetroot- and grape-seed-based supplement marketed to support healthy blood flow, blood pressure, and nitric ox...
Each serving of HumanN SuperBeets includes 500mg of beetroot powder (2 chews).
Read the full Humann Superbeets Heart Chews + Nebivolol Hydrochloride, Valsartan interactionKaraya GumBassora Tragacanth, goma Karaya, gomme Karaya, +14 more Possible
What it is: Karaya gum is a natural plant gum from the Sterculia tree that is mostly used as a bulk-forming laxative and as a thickener or adhesive in f...
Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption of drugs.
Read the full Karaya Gum + Nebivolol Hydrochloride, Valsartan interactionMarshmallowAlthaea Officinalis, altea, alteia, +16 more Possible
What it is: Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sor...
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow + Nebivolol Hydrochloride, Valsartan interactionN-methyltyramine Possible
What it is: N-methyltyramine is a natural compound related to tyramine that is found in bitter orange, barley, and other plants, and it is often added t...
In animal research, N-methyltyramine increased blood pressure.
Read the full N-methyltyramine + Nebivolol Hydrochloride, Valsartan interactionNicotinamide Riboside Possible
What it is: Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into NAD+, a molecule involved in cellular energy and repair.
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Nebivolol Hydrochloride, Valsartan interactionRabdosia RubescensRabdosia Rubescens, bing Ling Cao, blushred Rabdosia, +5 more Possible
What it is: Rabdosia rubescens is a Chinese herb traditionally used for sore throats, inflammation, and infections, and its compound oridonin has drawn...
In vitro research shows that oridonin, a constituent of Rabdosia rubescens, induces cytochrome P450 2C9 (CYP2C9) enzyme.
Read the full Rabdosia Rubescens + Nebivolol Hydrochloride, Valsartan interactionStevia Possible
What it is: Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by...
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia + Nebivolol Hydrochloride, Valsartan interactionTurkey Tail MushroomCoriolus Versicolor, cloud Mushroom Possible
What it is: Turkey tail is a woodland mushroom rich in polysaccharides like beta-glucans, and it is mainly used to support the immune system.
Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might inhibit CYP2C9.
Read the full Turkey Tail Mushroom + Nebivolol Hydrochloride, Valsartan interactionXanthan GumBacterial Polysaccharide, corn Sugar Gum, goma Xantana, +7 more Possible
What it is: Xanthan gum is a fermentation-made fiber widely used to thicken and stabilize foods and to thicken liquids for people with swallowing diffic...
Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Read the full Xanthan Gum + Nebivolol Hydrochloride, Valsartan interactionChanca PiedraPhyllanthus Niruri, amli, arranca-pedras, +16 more Unlikely
What it is: Chanca piedra is a tropical herb traditionally used as a 'stone breaker' for kidney and gallstones, and for liver and urinary health.
Theoretically, concomitant use of chanca piedra with antihypertensive drugs might have additive blood pressure lowering effects.
Read the full Chanca Piedra + Nebivolol Hydrochloride, Valsartan interactionCranberryVaccinium Macrocarpon, agrio, american Cranberry, +16 more Unlikely
What it is: Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate bu...
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry + Nebivolol Hydrochloride, Valsartan interactionDelta-9-tetrahydrocannabinol (thc)Bho, black Glass, budder, +9 more Unlikely
What it is: THC is the main mind-altering compound in cannabis and is best known for causing a 'high.' A prescription form (dronabinol) is approved for...
Theoretically, THC might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Delta-9-tetrahydrocannabinol (thc) + Nebivolol Hydrochloride, Valsartan interactionHempCannabis Sativa, cheungsam, fiber Hemp, +14 more Unlikely
What it is: Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generall...
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Hemp + Nebivolol Hydrochloride, Valsartan interactionMilk ThistleSilybum Marianum, artichaut Sauvage, blessed Milk Thistle, +12 more Unlikely
What it is: Milk thistle is a popular herbal supplement most often used for liver health, and its main active component is a group of compounds called s...
It is unclear if milk thistle inhibits CYP2C9; research is conflicting.
Read the full Milk Thistle + Nebivolol Hydrochloride, Valsartan interactionOstarine Unlikely
What it is: Ostarine (also called MK-2866 or enobosarm) is an experimental, unapproved drug known as a SARM (selective androgen receptor modulator), not...
Theoretically, ostarine might increase levels of drugs metabolized by CYP2C9, although clinical research suggests this is not clinically relevant.
Read the full Ostarine + Nebivolol Hydrochloride, Valsartan interactionRed CloverTrifolium Pratense, beebread, clovone, +17 more Unlikely
What it is: Red clover is a plant rich in isoflavones (plant compounds with weak estrogen-like activity) that is most often used for menopause symptoms...
Theoretically, red clover might increase levels of drugs metabolized by CYP2C9; however, a small clinical study found no effect.
Read the full Red Clover + Nebivolol Hydrochloride, Valsartan interactionValerianValeriana Officinalis, all-heal, amantilla, +10 more Unlikely
What it is: Valerian is an herb whose root is widely used as a natural sleep aid and for calming nerves.
Valerian does not seem to have a clinically relevant effect on levels of drugs metabolized by CYP2D6.
Read the full Valerian + Nebivolol Hydrochloride, Valsartan interactionCan You Take It With Nebivolol Hydrochloride, Valsartan?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Tribulus with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Full Tribulus + Nebivolol Hydrochloride, Valsartan answerCan you take Octopamine with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In humans, octopamine 450-600 mg daily increases blood pressure in hypotensive patients.
Full Octopamine + Nebivolol Hydrochloride, Valsartan answerCan you take Taurine with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Full Taurine + Nebivolol Hydrochloride, Valsartan answerCan you take Coleus with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hy...
Full Coleus + Nebivolol Hydrochloride, Valsartan answerCan you take Coltsfoot with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, excessive doses of coltsfoot may interfere with antihypertensive or cardiovascular therapy.
Full Coltsfoot + Nebivolol Hydrochloride, Valsartan answerCan you take Combretum Micranthum with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Combretum micranthum leaf with antihypertensive drugs might increase the risk of hypotension.
Full Combretum Micranthum + Nebivolol Hydrochloride, Valsartan answerCan you take Conjugated Linoleic Acid (cla) with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking CLA with antihypertensive drugs might increase the risk of hypotension.
Full Conjugated Linoleic Acid (cla) + Nebivolol Hydrochloride, Valsartan answerCan you take Coriander with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Full Coriander + Nebivolol Hydrochloride, Valsartan answerCan you take Corn Silk with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Full Corn Silk + Nebivolol Hydrochloride, Valsartan answerCan you take Corydalis Yanhusuo with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Corydalis yanhusuo might have additive effects with antihypertensive drugs.
Full Corydalis Yanhusuo + Nebivolol Hydrochloride, Valsartan answerCan you take Danshen with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking danshen with antihypertensive drugs might increase the risk of hypotension.
Full Danshen + Nebivolol Hydrochloride, Valsartan answerCan you take Dendrobium with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The dendrobium constituent dendrobine is reported to have convulsant effects.
Full Dendrobium + Nebivolol Hydrochloride, Valsartan answerCan you take Devil's Claw with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, devil's claw might increase levels of drugs metabolized by CYP2C9.
Full Devil's Claw + Nebivolol Hydrochloride, Valsartan answerCan you take Diosmin with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, diosmin might inhibit the metabolism of CYP2C9 substrates.
Full Diosmin + Nebivolol Hydrochloride, Valsartan answerCan you take Eleuthero with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
Full Eleuthero + Nebivolol Hydrochloride, Valsartan answerCan you take English Ivy with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, English ivy might increase the levels of drugs metabolized by CYP2D6.
Full English Ivy + Nebivolol Hydrochloride, Valsartan answerCan you take Eucalyptus with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
Full Eucalyptus + Nebivolol Hydrochloride, Valsartan answerCan you take European Barberry with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Full European Barberry + Nebivolol Hydrochloride, Valsartan answerCan you take European Mistletoe with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Full European Mistletoe + Nebivolol Hydrochloride, Valsartan answerCan you take False Unicorn with Nebivolol Hydrochloride, Valsartan?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Full False Unicorn + Nebivolol Hydrochloride, Valsartan answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Nebivolol Hydrochloride, Valsartan is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Nebivolol Hydrochloride, Valsartan, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Nebivolol Hydrochloride, Valsartan sits in 7 interaction categories. Open any one to see what the group means:
Antihypertensive Drugs 119 ingredients
Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.
119 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Cytochrome P450 2C9 (Cyp2C9) Substrates 64 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
64 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
60 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Oral Drugs 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Seizure Threshold Lowering Drugs 6 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
6 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Beta-Blockers 5 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
5 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Angiotensin Receptor Blockers (Arbs) 4 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
4 of the supplement ingredients on this page reach Nebivolol Hydrochloride, Valsartan through this category.
Related: does Nebivolol Hydrochloride, Valsartan deplete any nutrients?
Nebivolol Hydrochloride, Valsartan has 2 reported nutrient associations in the research literature — see the Nebivolol Hydrochloride, Valsartan nutrient depletion report.
Take a Supplement Product? Check the Whole Bottle Against Nebivolol Hydrochloride, Valsartan
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Nebivolol Hydrochloride, Valsartan.
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Products that contain Nebivolol Hydrochloride, Valsartan-interacting ingredients
Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Nebivolol Hydrochloride, Valsartan.
Nebivolol Hydrochloride, Valsartan & Supplements: Common Questions
What supplements interact with Nebivolol Hydrochloride, Valsartan?
Which Nebivolol Hydrochloride, Valsartan supplement interactions are the most serious?
Can I take vitamins or supplements while on Nebivolol Hydrochloride, Valsartan?
Do brands like Byvalson have the same supplement interactions as Nebivolol Hydrochloride, Valsartan?
Where do these interaction ratings come from?
Does Nebivolol Hydrochloride, Valsartan deplete any vitamins or nutrients?
What about Nebivolol Hydrochloride, Valsartan and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.