Medication interaction hub

What Supplements Interact with Betaxolol?

Betaxolol brand names: Kerlone, Betoptic. Every interaction below applies to the brands too.

143 Interactions 5 Major 118 Moderate 20 Minor
Curated & coded by · Clinical Pharmacist · Updated October 1, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Betaxolol? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Betaxolol against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Five of the 143 supplement ingredients that interact with betaxolol (Kerlone tablets for blood pressure, Betoptic drops for glaucoma) carry a major rating, so approach this page with real caution. Since betaxolol is a beta-blocker, nearly everything here plays on blood pressure. Most entries can drop yours too far, fish oil being a common example, while others raise it and work against the drug. Indian snakeroot worries me most; it can slow the heart on top of a medicine that already does.

A smaller cluster changes absorption. Activated charcoal can soak up betaxolol in the gut and weaken the dose, so keep the two well apart. The remaining 118 moderate and 20 minor entries are mostly additive blood pressure effects. Watch for dizziness, a slow pulse, or feeling faint when standing after adding a supplement; those are signs the combination is pushing betaxolol too far.

— , Clinical Pharmacist · July 18, 2026

Major 5 Moderate 118 Minor 20 No known interaction 1,309

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Betaxolol: Top Interactions at a Glance

The Betaxolol supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 143 interacting ingredients — plus 1,309 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Betaxolol Combinations Today

The Betaxolol + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Possible Fenugreek + Betaxololi

Fenugreek may also have an additive effect on blood pressure-lowering medications.

Read the full interaction Moderate Likelihood Possible Gamma-aminobutyric Acid (gaba) + Betaxololi

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.

Read the full interaction Moderate Likelihood Probable Fish Oil + Betaxololi

Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.

Read the full interaction Minor Likelihood Possible Coenzyme Q10 + Betaxololi

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.

Read the full interaction Moderate Likelihood Possible Gentian + Betaxololi

Theoretically, taking gentian with antihypertensive drugs might increase the risk of hypotension.

Read the full interaction Moderate Likelihood Possible Betony + Betaxololi

Theoretically, betony might have additive effects with blood pressure lowering drugs due to hypotensive activity of the glycosides found in betony.

Read the full interaction
The complete list

Every Supplement Checked Against Betaxolol

All 1,452 ingredients in our database, ranked by severity — 143 with a Betaxolol interaction on file and 1,309 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Betaxolol?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Fenugreek with Betaxolol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Fenugreek may also have an additive effect on blood pressure-lowering medications.

Full Fenugreek + Betaxolol answer

Can you take Gamma-aminobutyric Acid (gaba) with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.

Full Gamma-aminobutyric Acid (gaba) + Betaxolol answer

Can you take Fish Oil with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.

Full Fish Oil + Betaxolol answer

Can you take Coenzyme Q10 with Betaxolol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.

Full Coenzyme Q10 + Betaxolol answer

Can you take Gentian with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking gentian with antihypertensive drugs might increase the risk of hypotension.

Full Gentian + Betaxolol answer

Can you take N-acetyl Cysteine (nac) with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.

Full N-acetyl Cysteine (nac) + Betaxolol answer

Can you take Nattokinase with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, nattokinase might increase the risk of hypotension when used with antihypertensive drugs.

Full Nattokinase + Betaxolol answer

Can you take Niacin with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, niacin may increase the risk of hypotension when used with antihypertensive drugs.

Full Niacin + Betaxolol answer

Can you take Noni with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.

Full Noni + Betaxolol answer

Can you take Octopamine with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In humans, octopamine 450-600 mg daily increases blood pressure in hypotensive patients.

Full Octopamine + Betaxolol answer

Can you take Oregon Grape with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Oregon grape might increase the risk of hypotension when taken with antihypertensive drugs.

Full Oregon Grape + Betaxolol answer

Can you take Phellodendron with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phellodendron might have additive effects with antihypertensive drugs.

Full Phellodendron + Betaxolol answer

Can you take Pomegranate with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.

Full Pomegranate + Betaxolol answer

Can you take Quercetin with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking quercetin with antihypertensive drugs might increase the risk of hypotension.

Full Quercetin + Betaxolol answer

Can you take Rauvolfia Vomitoria with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Rauvolfia vomitoria might increase the risk of hypotension.

Full Rauvolfia Vomitoria + Betaxolol answer

Can you take Rauwolscine with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Full Rauwolscine + Betaxolol answer

Can you take Rehmannia with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.

Full Rehmannia + Betaxolol answer

Can you take Reishi Mushroom with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.

Full Reishi Mushroom + Betaxolol answer

Can you take Rhodiola with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.

Full Rhodiola + Betaxolol answer

Can you take Royal Jelly with Betaxolol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.

Full Royal Jelly + Betaxolol answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Betaxolol is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Betaxolol, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Betaxolol sits in 4 interaction categories. Open any one to see what the group means:

Antihypertensive Drugs 119 ingredients

Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.

119 of the supplement ingredients on this page reach Betaxolol through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Betaxolol through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Betaxolol through this category.

Beta-Blockers 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Betaxolol through this category.

About Betaxolol

Betaxolol is a beta blocker used to control high blood pressure.

Generic name: Betaxolol  ·  Brand names: Kerlone, Betoptic.

See the full Betaxolol drug information

Related: does Betaxolol deplete any nutrients?

Betaxolol has 2 reported nutrient associations in the research literature — see the Betaxolol nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Betaxolol

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Betaxolol.

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Pharmacist Counseling Corner

Betaxolol & Supplements: Common Questions

What supplements interact with Betaxolol?
In our interaction database, 143 supplement and herbal ingredients have an interaction with Betaxolol on file — 5 rated major, 118 moderate, and 20 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: American Hellebore, Tyramine, Activated Charcoal.
Which Betaxolol supplement interactions are the most serious?
The 5 major-rated combinations — led by American Hellebore, Tyramine, Activated Charcoal, American Mistletoe and Indian Snakeroot — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Betaxolol?
That depends entirely on which supplement. The honest answer for Betaxolol is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Kerlone have the same supplement interactions as Betaxolol?
Yes — Kerlone, Betoptic all contain Betaxolol, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Betaxolol deplete any vitamins or nutrients?
It might — Betaxolol has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Betaxolol nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Betaxolol and my other medications?
This page covers Betaxolol against supplements and herbal ingredients. Checking Betaxolol against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Betaxolol drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of October 1, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.