Interactions on record — worth a quick check against your medications. Based on 8 of 12 ingredients. Check your meds →
Dietary supplement

FiberMax Ingredients & Drug Interactions

by Advanced Naturals

FiberMax label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FiberMax against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FiberMax is a dietary supplement by Advanced Naturals with 12 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,185 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, Dietary Fiber, Guar Gum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against FiberMax by Advanced Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with FiberMax by Advanced Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of FiberMax by Advanced Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 13 active ingredients.
  • “Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “FiberMax Blend” is a proprietary blend — the label gives one combined amount (7,500 mg) without saying how much of each component you get.

FiberMax contains 14 ingredients including both soluble and insoluble fiber, plus botanical and probiotic components. The active ingredients are L-glutamine (an amino acid), slippery elm inner bark, marshmallow root, Bifidobacterium bifidum and Lactobacillus acidophilus (beneficial gut bacteria), fennel seed, FOS (a prebiotic fiber), triphala (an herbal blend), stevia extract (a sweetener), B. infantis (another probiotic), organic flax, and guar gum.

There are no other inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Optimal digestion and healthy bowel function.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Flatulence, Inflammatory bowel disease (IBD), Crohn disease — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea, Irritable bowel syndrome (IBS).
  • Also on file: Guar Gum is rated "Possibly Effective" for Constipation, Irritable bowel syndrome (IBS).

Evidence for most ingredients in FiberMax is limited. L-glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

Both probiotics — B. bifidum and L. acidophilus — are possibly effective for irritable bowel syndrome (IBS) and respiratory tract infections. Guar gum is possibly effective for high cholesterol, high blood pressure, IBS, and constipation.

Fennel is possibly effective for period pain (dysmenorrhea). Slippery elm, marshmallow, FOS, triphala, stevia, and the flax have insufficient evidence to rate their effectiveness for any condition in our data.

The evidence, ingredient by ingredient Black Psyllium Glutamine Slippery Elm Marshmallow Fennel Stevia Lactobacillus Acidophilus Guar Gum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 8 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated. L-glutamine can cause belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting—especially at high doses—and should be used only under medical supervision in people with kidney or liver disease.

Slippery elm is generally well tolerated short-term but carries limited safety data; contact dermatitis and urticaria have been reported, and the pollen is an allergen. Marshmallow is well tolerated short-term with limited human data.

Guar gum commonly causes abdominal pain, bloating, diarrhea, flatulence, and gas; it must be taken with plenty of water to avoid esophageal or bowel blockage. Both probiotics are generally well tolerated in healthy people but require caution in those with weakened immune systems.

Fennel may cause gastrointestinal discomfort, photosensitivity, allergic reactions, or rarely seizures and bronchial asthma. Stevia is generally well tolerated, with minor side effects like headache, dizziness, nausea, and muscle pain that often resolve within a week.

Side effects, ingredient by ingredient Black Psyllium Glutamine Slippery Elm Marshmallow Fennel Stevia Lactobacillus Acidophilus Guar Gum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 9 of the 9 matched ingredients can interact with medications — Black Psyllium, Fennel, Stevia, Marshmallow, Lactobacillus Acidophilus, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,186 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take FiberMax, double-check Moderate-severity interactions with oral medications generally, penicillin antibiotics, metformin, ethinyl estradiol (birth control), lithium, anticonvulsants, blood thinners and antiplatelet drugs, contraceptives, estrogen replacement therapy, tamoxifen, and ciprofloxacin. Also check Minor interactions with antihypertensive and antidiabetes drugs, and digoxin.

If you take antibiotics, space them 2+ hours away from this product. Use the search tool below with your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

FiberMax is a multi-ingredient fiber and probiotic blend with numerous documented interactions—most notably with oral medications, blood thinners, birth control, lithium, and antibiotics. If you take any prescription or over-the-counter medications, check each one against the interaction tool on this page before you start.

Those with kidney or liver disease should talk to their doctor first. A pharmacist can help you time doses correctly to minimize absorption problems.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 13 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FiberMax, straight from the product label.

Brand Advanced Naturals
Barcode (UPC) 631257535665
Net contents 12 oz.; 340 Gram(s)
Market status Off market
Date entered into DSLD May 24, 2018
DSLD ID 176841
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FiberMax by Advanced Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.5 Gram(s)
Maximum serving Sizes:
7.5 Gram(s)
Servings per container
45
UPC/BARCODE
631257535665
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
L-Glutamine0 NP--
Calories from Fat5 Calorie(s)--
Dietary Fiber2.5 Gram(s)10%
Protein2 Gram(s)4%
Total Fat0.5 Gram(s)1%
Soluble Fiber1 Gram(s)--
Insoluble Fiber1.5 Gram(s)--
Slippery Elm0 NP--
Marshmallow0 NP--
B. bifidum0 NP--
Fennel0 NP--
L. acidophilus0 NP--
FOS0 NP--
Triphala0 NP--
Stevia extract0 NP--
B. infantis0 NP--
Probiotic Blend0 NP--
organic Flax0 NP--
Guar Gum0 NP--
FiberMax Blend7500 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

FiberMax is an advanced daily fiber supplement with added ingredients for optimal digestion and healthy bowel function.

Quality, purity, and potency guaranteed through expiration.

Manufactured in USA in a GMP facility.

Packed by weight, not volume. Contents may settle during storage and handling.

Natural digestive care

Promotes regularity Supports intestinal health

Formula

It contains: Organic Flax fiber, FOS, L-Glutamine, and probiotics.

Advanced fiber for sensitive colons

May contain mild traces of milk proteins from fermentation ingredients.

Formulation

Gluten free Soy free No artificial ingredients

Pleasant taste, gluten free & psyllium free

Storage

Store in a dry place at 59-86 degrees F (15-30 degrees C).

Precautions

Keep out of reach of children.

Consult your healthcare professional before using this or any product if you are pregnant, nursing, trying to conceive, taking medication, or have a medical condition.

Notice: Using this supplement without at least a full glass of liquid may cause choking. Do not use this supplement if you have difficulty in swallowing, acute cough, or obstructed bowel.

Tamper evident: Do not use if safety seal is broken or missing.

May contain mild traces of milk proteins from fermentation ingredients.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

#16904 030316 90543C

FDA Statement of Identity

Fiber Supplement

Suggested/Recommended/Usage/Directions

45-day supply

Directions: Take one scoop in 8 ounces of water or juice. Drink plenty of water while using this product.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FiberMax by Advanced Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FiberMax label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FiberMax by Advanced Naturals

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.5 Gram(s) Dosage formPowder Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
2.5 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions
  • › Soluble Fiber
  • › Insoluble Fiber

Protein

2 Gram(s) per serving

FiberMax Blend

7500 mg per serving

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

FiberMax by Advanced Naturals Drug Interactions

Want to check YOUR meds against FiberMax?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,185Drugs
2,153 Moderate 32 Minor

Ingredients driving the most interactions

Marshmallow 2,040
Dietary Fiber 2,025
Guar Gum 2,025
Slippery Elm 2,022
Fennel 740

Individual Drug Interactions

The ingredients in FiberMax interact with 2,185 drugs. Click any drug to see the details.

8 of the 12 ingredients in FiberMax interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Dietary Fiber Guar Gum Slippery Elm Fennel Stevia extract Probiotic Blend L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in FiberMax with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Guar Gum5 drug types · 2,025 drugs

Ethinyl Estradiol

Theoretically, guar gum might reduce the absorption of ethinyl estradiol, potentially decreasing its effectiveness.
Animal research shows that taking guar gum with ethinyl estradiol decreases ethinyl estradiol absorption. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Metformin (Glucophage)

Guar gum might reduce the absorption of metformin, potentially decreasing its effectiveness.
A small study in healthy volunteers shows that guar gum reduces the absorption rate of metformin.

Likelihood Probable Evidence B
Oral Drugs

Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Clinical research shows that guar gum reduces or slows absorption of medications such as penicillin and metformin. To avoid changes in absorption, take guar gum 30-60 minutes after oral medications.

Likelihood Possible Evidence B
Penicillin

Guar gum might reduce the absorption of penicillin, potentially decreasing its effectiveness.
A small clinical study in healthy volunteers shows that taking guar gum with penicillin results in decreased penicillin absorption and reduced penicillin levels.

Likelihood Probable Evidence B
Digoxin (Lanoxin)

Guar gum might slow digoxin absorption, but it does not seem to impact how much digoxin is absorbed overall.
Two small studies in healthy volunteers show no change in the overall extent of digoxin absorption, although early absorption was slowed, when taken with guar gum.

Likelihood Possible Evidence B
Guar Gum full monograph & interactions

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm full monograph & interactions

Fennel6 drug types · 740 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.

Likelihood Possible Evidence D
Ciprofloxacin (Cipro)

Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.

Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.

In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.

Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.

Likelihood Possible Evidence D
Fennel full monograph & interactions

Stevia extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia extract full monograph & interactions

Probiotic Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Blend full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FiberMax, from the product label.

Advanced Naturals

See all Advanced Naturals products
Name
Advanced Naturals
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-690-9988
Web Address
www.advancednaturals.com
Pharmacist Counseling Corner

FiberMax by Advanced Naturals: Common Questions

Does FiberMax by Advanced Naturals interact with any medications?
Yes. Based on its ingredients, FiberMax has a known interaction with 2,185 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FiberMax contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take FiberMax while I'm on antibiotics?
The probiotics in FiberMax (B. bifidum and L. acidophilus) contain live organisms that antibiotics can kill, reducing their benefit. Separate them by at least 2 hours—take your antibiotic, wait 2+ hours, then take FiberMax. Ask your pharmacist or doctor for the best timing based on your specific antibiotic.
Does FiberMax have any fillers or binders?
No other inactive ingredients are listed for FiberMax.
What are the probiotics in this product for?
B. bifidum and L. acidophilus are beneficial bacteria that support gut health. They're possibly effective for irritable bowel syndrome and respiratory tract infections, though evidence is still emerging for many other uses.
Can I take FiberMax with my blood pressure or diabetes medication?
Stevia extract (a Minor interaction) may lower blood pressure further or increase hypoglycemia (low blood sugar) risk when combined with those drugs. Talk to your pharmacist or doctor about whether it's safe for you.
What are the most common side effects of FiberMax?
The fiber ingredients commonly cause bloating, gas, diarrhea, flatulence, and abdominal discomfort—especially when you start. These usually improve if you begin with a small dose and increase gradually. Always take it with plenty of water.
Is FiberMax safe during pregnancy or breastfeeding?
L-glutamine is rated likely safe in pregnancy. Fennel is rated possibly unsafe in both pregnancy and breastfeeding. Marshmallow safety data are too limited to advise either way in pregnancy or breastfeeding. Stevia and guar gum lack clear safety ratings for these stages. Talk with your doctor or pharmacist about your individual situation before using FiberMax.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FiberMax label
Go deeper

The Full Monographs Behind FiberMax’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Fennel

Interacts with 740 drugs

Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...

Read the full Fennel monograph → Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Guar Gum

Interacts with 2,025 drugs

Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity. It is generally safe in food amounts, but concentrated...

Read the full Guar Gum monograph →
Sources

Sources & How We Checked

FiberMax's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 112 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
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Black Psyllium 18 references
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Slippery Elm 3 references
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Marshmallow 5 references
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Bifidobacterium Bifidum 7 references
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See these in context on the Bifidobacterium Bifidum monograph →

Fennel 17 references
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Lactobacillus Acidophilus 15 references
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  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
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Stevia 10 references
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  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
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Guar Gum 26 references
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  21. Cicero, A. F., Derosa, G., Manca, M., Bove, M., Borghi, C., and Gaddi, A. V. Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. Clin.Exp.Hyp PubMed
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  25. Brillantino A, Iacobellis F, Izzo G, et al. Maintenance therapy with partially hydrolyzed guar gum in the conservative treatment of chronic anal fissure: results of a prospective, randomized study. Biomed Res Int 2014;2014:964942. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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