Medication interaction hub

What Supplements Interact with dabigatran?

dabigatran brand names: Pradaxa, Pradax. Every interaction below applies to the brands too.

235 Interactions 4 Major 201 Moderate 30 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with dabigatran? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check dabigatran against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Dabigatran (Pradaxa) is a blood thinner prescribed to prevent strokes and dangerous clots, which makes the stakes for mixing in supplements higher than for most medicines, and I would go through this list with real care. Of the 235 ingredients on file, 202 could add to dabigatran's blood-thinning effect and increase bruising or bleeding, and danshen sits among the four rated major for exactly that reason.

The danger can also run the opposite way. St. John's wort, another of the major four, pushes dabigatran out of the body faster and can leave you underprotected against the very clots it exists to prevent. Activated charcoal and a handful of other products can block the pill from being absorbed at all, so keep those well separated from your dose. The remaining 201 moderate and 30 minor entries mostly repeat the bleeding theme at lower intensity.

— , Clinical Pharmacist · July 18, 2026

Major 4 Moderate 201 Minor 30 No known interaction 1,217

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

dabigatran: Top Interactions at a Glance

The dabigatran supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 235 interacting ingredients — plus 1,217 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked dabigatran Combinations Today

The dabigatran + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Melatonin + dabigatrani

Theoretically, melatonin may have anticoagulant effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Major Likelihood Probable Piracetam + dabigatrani

Theoretically, concomitant use of piracetam and anticoagulant/antiplatelet drugs might increase the risk of bleeding.

Read the full interaction Moderate Likelihood Unlikely Arnica + dabigatrani

Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.

Read the full interaction Minor Likelihood Unlikely Magnesium + dabigatrani

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.

Read the full interaction Moderate Likelihood Unlikely Fenugreek + dabigatrani

Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.

Read the full interaction Minor Likelihood Unlikely Fucus Vesiculosus + dabigatrani

Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.

Read the full interaction
The complete list

Every Supplement Checked Against dabigatran

All 1,452 ingredients in our database, ranked by severity — 235 with a dabigatran interaction on file and 1,217 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With dabigatran?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Melatonin with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, melatonin may have anticoagulant effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet dru...

Full Melatonin + dabigatran answer

Can you take Piracetam with dabigatran?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use of piracetam and anticoagulant/antiplatelet drugs might increase the risk of bleeding.

Full Piracetam + dabigatran answer

Can you take Arnica with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.

Full Arnica + dabigatran answer

Can you take Magnesium with dabigatran?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.

Full Magnesium + dabigatran answer

Can you take Fenugreek with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.

Full Fenugreek + dabigatran answer

Can you take Cilantro with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that extracts of cilantro can inhibit platelet aggregation.

Full Cilantro + dabigatran answer

Can you take Cinchona with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking cinchona might increase the drug effects and risk of bleeding with anticoagulant and antiplatelet drugs.

Full Cinchona + dabigatran answer

Can you take Cnidium with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Laboratory research shows that osthol, a constituent of cnidium, inhibits blood clotting and the activity of platelets.

Full Cnidium + dabigatran answer

Can you take Cocoa with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cocoa may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Cocoa + dabigatran answer

Can you take Cod Liver Oil with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cod liver oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Cod Liver Oil + dabigatran answer

Can you take Codonopsis with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, codonopsis liquor might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Full Codonopsis + dabigatran answer

Can you take Coleus with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.

Full Coleus + dabigatran answer

Can you take Coltsfoot with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use might increase the risk of bleeding due to decreased platelet aggregation.

Full Coltsfoot + dabigatran answer

Can you take Conjugated Linoleic Acid (cla) with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CLA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Conjugated Linoleic Acid (cla) + dabigatran answer

Can you take Cordyceps with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Full Cordyceps + dabigatran answer

Can you take Corydalis Yanhusuo with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Corydalis Yanhusuo + dabigatran answer

Can you take Cumin with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cumin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Full Cumin + dabigatran answer

Can you take Cypress with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro evidence shows that cypress cone extract inhibits blood coagulation in a concentration-dependent manner.

Full Cypress + dabigatran answer

Can you take Dandelion with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.

Full Dandelion + dabigatran answer

Can you take Delta-9-tetrahydrocannabinol (thc) with dabigatran?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, THC might alter levels of drugs that are substrates of P-glycoprotein (P-gp).

Full Delta-9-tetrahydrocannabinol (thc) + dabigatran answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) dabigatran is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by dabigatran, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

dabigatran sits in 3 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach dabigatran through this category.

P-Glycoprotein Substrates 37 ingredients

A drug-transport group: these medications are moved in and out of cells by the P-glycoprotein pump. Supplements that affect the pump can change how much of the drug is absorbed or kept in the body.

37 of the supplement ingredients on this page reach dabigatran through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach dabigatran through this category.

About dabigatran

Dabigatran is a direct thrombin inhibitor anticoagulant used to treat blood clots and prevent strokes in patients with irregular heartbeats.

Generic name: dabigatran  ·  Brand names: Pradaxa, Pradax.

See the full Dabigatran drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against dabigatran

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against dabigatran.

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Pharmacist Counseling Corner

dabigatran & Supplements: Common Questions

What supplements interact with dabigatran?
In our interaction database, 235 supplement and herbal ingredients have an interaction with dabigatran on file — 4 rated major, 201 moderate, and 30 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Activated Charcoal, Danshen, Piracetam.
Which dabigatran supplement interactions are the most serious?
The 4 major-rated combinations — led by Activated Charcoal, Danshen, Piracetam and St. John's Wort — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on dabigatran?
That depends entirely on which supplement. The honest answer for dabigatran is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Pradaxa have the same supplement interactions as dabigatran?
Yes — Pradaxa, Pradax all contain dabigatran, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about dabigatran and my other medications?
This page covers dabigatran against supplements and herbal ingredients. Checking dabigatran against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Dabigatran drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.