Medication interaction hub

What Supplements Interact with Diltiazem, Enalapril?

Diltiazem, Enalapril brand name: Teczem. Every interaction below applies to the brands too.

271 Interactions 9 Major 220 Moderate 42 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Diltiazem, Enalapril? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Diltiazem, Enalapril against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Anyone taking Teczem (diltiazem with enalapril) for blood pressure should know that most of the 271 supplements with an interaction on file hit the same targets as the drug itself. The bulk either add to its blood-pressure-lowering effect or change how the body handles diltiazem, which is processed by an enzyme called CYP3A4. Nine entries rate major, and this is a list that deserves genuine respect. Grapefruit can push diltiazem levels up, while St. John's wort can pull them down until the drug quietly stops working.

The enalapril half raises a different flag. A few herbs stress the kidneys directly, and potassium supplements, including the salt substitutes people buy for heart health, can drive potassium too high when paired with an ACE inhibitor like this one. Beyond the nine majors, 220 entries rate moderate and 42 minor, mostly additive pressure effects or shifts in how much of the drug actually reaches your blood.

— , Clinical Pharmacist · July 18, 2026

Major 9 Moderate 220 Minor 42 No known interaction 1,181

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Diltiazem, Enalapril: Top Interactions at a Glance

The Diltiazem, Enalapril supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 271 interacting ingredients — plus 1,181 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Diltiazem, Enalapril Combinations Today

The Diltiazem, Enalapril + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Probable Calcium + Diltiazem, Enalaprili

Theoretically, calcium may reduce the therapeutic effects of diltiazem.

Read the full interaction Moderate Likelihood Possible Hibiscus Sabdariffa + Diltiazem, Enalaprili

Theoretically, taking Hibiscus sabdariffa with antihypertensive drugs might increase the risk of hypotension.

Read the full interaction Major Likelihood Probable Coleus + Diltiazem, Enalaprili

Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.

Read the full interaction Minor Likelihood Unlikely Capsicum + Diltiazem, Enalaprili

Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.

Read the full interaction Moderate Likelihood Possible Black Tea + Diltiazem, Enalaprili

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Likely Potassium + Diltiazem, Enalaprili

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.

Read the full interaction
The complete list

Every Supplement Checked Against Diltiazem, Enalapril

All 1,452 ingredients in our database, ranked by severity — 271 with a Diltiazem, Enalapril interaction on file and 1,181 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Diltiazem, Enalapril?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Calcium with Diltiazem, Enalapril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, calcium may reduce the therapeutic effects of diltiazem.

Full Calcium + Diltiazem, Enalapril answer

Can you take Hibiscus Sabdariffa with Diltiazem, Enalapril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Hibiscus sabdariffa with antihypertensive drugs might increase the risk of hypotension.

Full Hibiscus Sabdariffa + Diltiazem, Enalapril answer

Can you take Coleus with Diltiazem, Enalapril?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.

Full Coleus + Diltiazem, Enalapril answer

Can you take Capsicum with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.

Full Capsicum + Diltiazem, Enalapril answer

Can you take Black Tea with Diltiazem, Enalapril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Black Tea + Diltiazem, Enalapril answer

Can you take Coenzyme Q10 with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.

Full Coenzyme Q10 + Diltiazem, Enalapril answer

Can you take Dendrobium with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. The dendrobium constituent dendrobine is reported to have hypotensive effects.

Full Dendrobium + Diltiazem, Enalapril answer

Can you take Dulse with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, dulse might increase the risk of hyperkalemia when taken with ACEIs.

Full Dulse + Diltiazem, Enalapril answer

Can you take Fenugreek with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Fenugreek may also have an additive effect on blood pressure-lowering medications.

Full Fenugreek + Diltiazem, Enalapril answer

Can you take Fucus Vesiculosus with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.

Full Fucus Vesiculosus + Diltiazem, Enalapril answer

Can you take Green Coffee with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking green coffee with antihypertensive drugs might increase the risk of hypotension.

Full Green Coffee + Diltiazem, Enalapril answer

Can you take Guarana with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Guarana + Diltiazem, Enalapril answer

Can you take Hemp with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.

Full Hemp + Diltiazem, Enalapril answer

Can you take Honey with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.

Full Honey + Diltiazem, Enalapril answer

Can you take Hops with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.

Full Hops + Diltiazem, Enalapril answer

Can you take Humann Superbeets Heart Chews with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Each serving of HumanN SuperBeets includes 500mg of beetroot powder (2 chews).

Full Humann Superbeets Heart Chews + Diltiazem, Enalapril answer

Can you take Karaya Gum with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...

Full Karaya Gum + Diltiazem, Enalapril answer

Can you take Marshmallow with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Full Marshmallow + Diltiazem, Enalapril answer

Can you take N-methyltyramine with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. In animal research, N-methyltyramine increased blood pressure.

Full N-methyltyramine + Diltiazem, Enalapril answer

Can you take Nicotinamide Riboside with Diltiazem, Enalapril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.

Full Nicotinamide Riboside + Diltiazem, Enalapril answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Diltiazem, Enalapril is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Diltiazem, Enalapril, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Diltiazem, Enalapril sits in 11 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Antihypertensive Drugs 119 ingredients

Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.

119 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

P-Glycoprotein Substrates 37 ingredients

A drug-transport group: these medications are moved in and out of cells by the P-glycoprotein pump. Supplements that affect the pump can change how much of the drug is absorbed or kept in the body.

37 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Cytochrome P450 3A4 (Cyp3A4) Inhibitors 13 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

13 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Ace Inhibitors (Aceis) 12 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

12 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Cytochrome P450 1A2 (Cyp1A2) Inhibitors 10 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

10 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Calcium Channel Blockers 9 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

9 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Diltiazem (Cardizem, Others) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Diltiazem, Enalapril through this category.

Related: does Diltiazem, Enalapril deplete any nutrients?

Diltiazem, Enalapril has 2 reported nutrient associations in the research literature — see the Diltiazem, Enalapril nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Diltiazem, Enalapril

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Diltiazem, Enalapril.

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Pharmacist Counseling Corner

Diltiazem, Enalapril & Supplements: Common Questions

What supplements interact with Diltiazem, Enalapril?
In our interaction database, 271 supplement and herbal ingredients have an interaction with Diltiazem, Enalapril on file — 9 rated major, 220 moderate, and 42 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: American Hellebore, Grapefruit, Siberian Cocklebur.
Which Diltiazem, Enalapril supplement interactions are the most serious?
The 9 major-rated combinations — led by American Hellebore, Grapefruit, Siberian Cocklebur, Tyramine and Activated Charcoal — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Diltiazem, Enalapril?
That depends entirely on which supplement. The honest answer for Diltiazem, Enalapril is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Teczem have the same supplement interactions as Diltiazem, Enalapril?
Yes — Teczem all contain Diltiazem, Enalapril, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Diltiazem, Enalapril deplete any vitamins or nutrients?
It might — Diltiazem, Enalapril has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Diltiazem, Enalapril nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Diltiazem, Enalapril and my other medications?
This page covers Diltiazem, Enalapril against supplements and herbal ingredients. Checking Diltiazem, Enalapril against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.