Medication interaction hub

What Supplements Interact with Ranitidine Bismuth Citrate?

Ranitidine Bismuth Citrate brand name: Tritec. Every interaction below applies to the brands too.

73 Interactions 2 Major 43 Moderate 28 Minor
Curated & coded by · Clinical Pharmacist · Updated September 24, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Ranitidine Bismuth Citrate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Ranitidine Bismuth Citrate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

73 supplements and herbal ingredients have interactions with Ranitidine Bismuth Citrate on file in the HelloPharmacist interaction database — 2 rated major, 43 moderate, and 28 minor. The most serious involve Activated Charcoal and St. John's Wort.

Our assessment: with 2 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Ranitidine Bismuth Citrate.

Major 2 Moderate 43 Minor 28 No known interaction 1,379

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Ranitidine Bismuth Citrate: Top Interactions at a Glance

The most significant Ranitidine Bismuth Citrate supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 73 interacting ingredients — plus 1,379 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Ranitidine Bismuth Citrate + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Activated Charcoal + Ranitidine Bismuth Citratei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable St. John's Wort + Ranitidine Bismuth Citratei

St.

Read the full interaction
The complete list

Every Supplement Checked Against Ranitidine Bismuth Citrate

All 1,452 ingredients in our database, ranked by severity — 73 with a Ranitidine Bismuth Citrate interaction on file and 1,379 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Ranitidine Bismuth Citrate?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take St. John's Wort with Ranitidine Bismuth Citrate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. St.

Full St. John's Wort + Ranitidine Bismuth Citrate answer

Can you take Devil's Claw with Ranitidine Bismuth Citrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, devil's claw might increase levels of P-glycoprotein substrates.

Full Devil's Claw + Ranitidine Bismuth Citrate answer

Can you take Neem with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, neem leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.

Full Neem + Ranitidine Bismuth Citrate answer

Can you take Oregon Grape with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Oregon grape might increase serum levels of drugs that are P-glycoprotein (P-gp) substrates.

Full Oregon Grape + Ranitidine Bismuth Citrate answer

Can you take Quercetin with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the effects and adverse effects of OAT3 substrates.

Full Quercetin + Ranitidine Bismuth Citrate answer

Can you take Rabdosia Rubescens with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Rabdosia rubescens might increase levels of p-glycoprotein substrates.

Full Rabdosia Rubescens + Ranitidine Bismuth Citrate answer

Can you take Rhodiola with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rhodiola might increase levels of P-glycoprotein substrates.

Full Rhodiola + Ranitidine Bismuth Citrate answer

Can you take Sage with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sage might increase levels of drugs transported by P-glycoprotein.

Full Sage + Ranitidine Bismuth Citrate answer

Can you take Schisandra with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Schisandra might increase the levels and clinical effects of P-glycoprotein substrates.

Full Schisandra + Ranitidine Bismuth Citrate answer

Can you take Slippery Elm with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Ranitidine Bismuth Citrate answer

Can you take Strawberry with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.

Full Strawberry + Ranitidine Bismuth Citrate answer

Can you take Sweet Orange with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Sweet orange juice seems to modulate P-glycoprotein (P-gp), which might affect the blood levels of P-gp substrates.

Full Sweet Orange + Ranitidine Bismuth Citrate answer

Can you take Tragacanth with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.

Full Tragacanth + Ranitidine Bismuth Citrate answer

Can you take White Pepper with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, white pepper might increase levels of p-glycoprotein substrates.

Full White Pepper + Ranitidine Bismuth Citrate answer

Can you take Wine with Ranitidine Bismuth Citrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use might increase blood alcohol levels and adverse effects.

Full Wine + Ranitidine Bismuth Citrate answer

Can you take Thyroid Extract with Ranitidine Bismuth Citrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Food and medications can interfere with thyroid hormone absorption.

Full Thyroid Extract + Ranitidine Bismuth Citrate answer

Can you take Agar with Ranitidine Bismuth Citrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.

Full Agar + Ranitidine Bismuth Citrate answer

Can you take Aletris with Ranitidine Bismuth Citrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of H2-blockers.

Full Aletris + Ranitidine Bismuth Citrate answer

Can you take Algin with Ranitidine Bismuth Citrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, algin can alter the absorption of oral drugs.

Full Algin + Ranitidine Bismuth Citrate answer

Can you take Alpinia with Ranitidine Bismuth Citrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, alpinia might decrease the effectiveness of H2-blockers.

Full Alpinia + Ranitidine Bismuth Citrate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Ranitidine Bismuth Citrate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Ranitidine Bismuth Citrate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Ranitidine Bismuth Citrate sits in 5 interaction categories. Open any one to see what the group means:

P-Glycoprotein Substrates 37 ingredients

A drug-transport group: these medications are moved in and out of cells by the P-glycoprotein pump. Supplements that affect the pump can change how much of the drug is absorbed or kept in the body.

37 of the supplement ingredients on this page reach Ranitidine Bismuth Citrate through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Ranitidine Bismuth Citrate through this category.

H2-Blockers 14 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

14 of the supplement ingredients on this page reach Ranitidine Bismuth Citrate through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Ranitidine Bismuth Citrate through this category.

Cytochrome P450 2D6 (Cyp2D6) Inhibitors 3 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

3 of the supplement ingredients on this page reach Ranitidine Bismuth Citrate through this category.

About Ranitidine Bismuth Citrate

Ranitidine is an H2 blocker used to treat ulcers, acid reflux, heartburn, and conditions where the stomach produces too much acid.

Generic name: Ranitidine Bismuth Citrate  ·  Brand name: Tritec.

See the full Ranitidine drug information

Related: does Ranitidine Bismuth Citrate deplete any nutrients?

Ranitidine Bismuth Citrate has 6 reported nutrient associations in the research literature — see the Ranitidine Bismuth Citrate nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Ranitidine Bismuth Citrate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Ranitidine Bismuth Citrate.

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Products that contain Ranitidine Bismuth Citrate-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Ranitidine Bismuth Citrate.

Standardized St. John's Wort 600 mg by Nature's Truth contains St. John's Wort St. John's Wort-IMT by SP Standard Process contains St. John's Wort St John's Wort Extract by SuperSmart contains St. John's Wort St John's Wort 400 mg by Signature Supplements contains St. John's Wort
Pharmacist Counseling Corner

Ranitidine Bismuth Citrate & Supplements: Common Questions

What supplements interact with Ranitidine Bismuth Citrate?
Our database currently documents 73 ingredients with a known Ranitidine Bismuth Citrate interaction (2 major, 43 moderate, 28 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 73. The highest-ranked right now: Activated Charcoal, St. John's Wort, Coffee Charcoal.
Which Ranitidine Bismuth Citrate supplement interactions are the most serious?
Focus on the major group: Activated Charcoal and St. John's Wort. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Ranitidine Bismuth Citrate?
Plenty of supplements coexist fine with Ranitidine Bismuth Citrate; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Tritec have the same supplement interactions as Ranitidine Bismuth Citrate?
Yes — Tritec all contain Ranitidine Bismuth Citrate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Ranitidine Bismuth Citrate deplete any vitamins or nutrients?
It might — Ranitidine Bismuth Citrate has 6 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Ranitidine Bismuth Citrate nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Ranitidine Bismuth Citrate and my other medications?
This page covers Ranitidine Bismuth Citrate against supplements and herbal ingredients. Checking Ranitidine Bismuth Citrate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Ranitidine drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 24, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.