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Dietary supplement

Glutamine Micronized Unflavored Ingredients & Drug Interactions

by Dymatize

Powder Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Glutamine Micronized Unflavored is a dietary supplement by Dymatize with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Glutamine Micronized Unflavored by Dymatize

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine, an amino acid your body naturally produces. There are no inactive ingredients listed for this powder.

L-glutamine plays a role in immune function, gut health, and muscle recovery, and your body's own supply is drawn from dietary protein and muscle tissue. This single-ingredient format lets you control the dose and mix it into beverages or food as you prefer.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle support and athletic performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, muscle strength, recovery.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Exercise-induced muscle damage.

The evidence we hold shows L-glutamine is effective for sickle cell disease. It's rated possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

That means there's some evidence it may help in those situations, but it's not as strong or consistent as the sickle cell data. If you're considering glutamine for a specific condition, talk it over with your doctor to see whether the evidence fits your situation.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, L-glutamine is generally well tolerated in healthy adults. The most common side effects are gastrointestinal ones — belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and abdominal pain.

Headache and musculoskeletal pain have also been reported. Dizziness and headache can occur, though one patient's dizziness resolved after the dose was cut in half.

If you have kidney or liver disease, use glutamine only under a doctor's supervision. There isn't enough safety data to recommend supplemental doses during pregnancy or breastfeeding unless your doctor advises it.

People with bipolar disorder should be aware that glutamine has been linked to mania or hypomania in rare cases.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use anticonvulsant medications (drugs to prevent or control seizures). Glutamine is theoretically thought to work against how these drugs function, though this hasn't been reported in actual patients yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine is a single-ingredient amino acid supplement backed by solid evidence for sickle cell disease and promising evidence for wasting related to HIV/AIDS and recovery from surgery or critical illness. It's generally well tolerated, though GI side effects are common.

If you take anticonvulsant medications or have kidney or liver disease, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Micronized Unflavored, straight from the product label.

Brand Dymatize
Barcode (UPC) 705016163007
Net contents 10.58 Ounce(s); 300 Gram(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218148
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Micronized Unflavored by Dymatize, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.75 tsp
Maximum serving Sizes:
1.75 tsp
Servings per container
65
UPC/BARCODE
705016163007
IngredientAmount% DV
Calories20 Calorie(s)--
L-Glutamine4.5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Informed-Choice.org Trusted by sport

Formulation

Informed Choice is a quality assurance program that certifies that all nutritional supplements and/or ingredients have been regularly tested for banned substances by the world class sports anti-doping lab, LGC.

Fast absorbing Muscle support

Real science & quality Dymatize products are formulated based on the latest science and are always manufactured in GMP Certified facilities. They are banned substance tested for athlete’s reassurance under the Informed-Sport program (www.informed-sport.org).

Gluten free No Dyes

Produced in the USA with domestic and international ingredients.

Formula

Dymatize Glutamine Micronized provides 4.5g of L-Glutamine per serving

L-Glutamine is one of the most abundant amino acids found in the body and provides daily muscle support.

Glutamine 4.5g

General Statements

Known for quality and proven performance, Dymatize Glutamine is the choice of serious athletes and trainers worldwide who need to perform at their best.

Get Dymatized

Sold by weight not volume

65 servings

Perfecting athletic nutrition Born in the USA

Suggested/Recommended/Usage/Directions

Dymatize Glutamine is unflavored and mixes easily so that it can be added to flavored beverages, shakes or other recipes.

Directions: Add 1 3/4 tsp. daily to cold water or your favorite beverage.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Precautions

Do not use if pregnant or lactating.

Consult a physician prior to use if you have any medical condition.

Use only as directed.

Keep out of the reach of children.

Storage

Storage Conditions: Store at room temperature in a dry place.

See for yourself

Glutamine Micronized Unflavored by Dymatize label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Glutamine Micronized Unflavored by Dymatize

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.75 tsp Dosage formPowder Servings per container65 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
4.5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Glutamine Micronized Unflavored by Dymatize Drug Interactions

Want to check YOUR meds against Glutamine Micronized Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Micronized Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Glutamine Micronized Unflavored, from the product label.

Dymatize

See all Dymatize products
Name
Dymatize Enterprises, LLC
City
Dallas
State
TX
ZipCode
75207
Phone Number
(888) 334-5326
Web Address
Dymatize.com
Pharmacist Counseling Corner

Glutamine Micronized Unflavored by Dymatize: Common Questions

Does Glutamine Micronized Unflavored by Dymatize interact with any medications?
Yes. Based on its ingredients, Glutamine Micronized Unflavored has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Micronized Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant or breastfeeding?
The data we hold shows L-glutamine is likely safe during pregnancy. However, there isn't enough reliable safety information for breastfeeding — talk with your doctor or pharmacist about whether it's right for you in that situation.
What are the most common side effects?
Gastrointestinal issues are most frequent: belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and abdominal pain. Headache and musculoskeletal pain have also been reported. Most people tolerate it well, but if your stomach is sensitive, start with a smaller dose.
Does glutamine actually work?
It's effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence suggests it may help, but it's not as definitive. Your doctor can tell you whether it's appropriate for your specific situation.
Can I take this if I have kidney or liver disease?
You should only use glutamine under medical supervision if you have kidney or liver disease. Talk with your doctor before starting.
What is L-glutamine and why is it in this product?
L-glutamine is an amino acid your body makes naturally from protein. It supports immune function, gut health, and muscle recovery. This product gives you an extra supply in a powder form you can mix into drinks or food.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Micronized Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Micronized Unflavored label
Go deeper

The Full Monographs Behind Glutamine Micronized Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Glutamine Micronized Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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