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Dietary supplement

L-Glutamine Chew Delicious Grape Ingredients & Drug Interactions

by GNC Pro Performance

L-Glutamine Chew Delicious Grape label
See full label image
Other (e.g. Tea Bag) Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking L-Glutamine Chew Delicious Grape against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

L-Glutamine Chew Delicious Grape is a dietary supplement by GNC Pro Performance with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine, Micronized. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against L-Glutamine Chew Delicious Grape by GNC Pro Performance

Ask about any prescription or over-the-counter medication and we check it for interactions with L-Glutamine Chew Delicious Grape by GNC Pro Performance — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of L-Glutamine Chew Delicious Grape by GNC Pro Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine, micronized (a finely powdered form that dissolves more easily). L-glutamine is an amino acid your body uses for muscle recovery, immune function, and gut health.

The rest is inactive ingredients — corn syrup, maltodextrin, palm oil, natural flavors, soy lecithin, citric acid, fruit juice, vegetable juice, glycerin, malic acid, and sucralose — which give the chew its flavor and texture.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle function and immune response support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Oral mucositis, Critical illness (trauma) — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Radiation-induced diarrhea.

L-glutamine is rated Effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence rates it as Possibly Effective — meaning there's some supporting data, but more research is needed to be certain.

The rating for each condition reflects what the research shows so far, not a guarantee of results in every person.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults. The most common side effects from oral doses are digestive — belching, bloating, constipation, flatulence, nausea, vomiting, diarrhea, and stomach pain — along with headache and musculoskeletal pain.

A few rare cases of dizziness, mania, or hypomania have been reported, and high doses (10–30 grams daily) used in clinical trials have caused GI upset. If you have kidney or liver disease, use this only under medical supervision.

During pregnancy, L-glutamine is rated Likely Safe. There isn't enough reliable safety data for breastfeeding, so talk with your doctor or pharmacist before using supplemental doses while nursing.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure drugs), double-check this product with your doctor or pharmacist first — glutamine may theoretically reduce how well they work. No other major medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement may help with sickle cell disease or support recovery after surgery or critical illness, though evidence for those last two is still developing. If you take seizure medications, check with your doctor or pharmacist before starting — the interaction is theoretical but worth discussing.

Generally well tolerated, though it can cause digestive upset, especially at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Glutamine Chew Delicious Grape, straight from the product label.

Brand GNC Pro Performance
Barcode (UPC) 048107169961
Net contents 60 Chew(s); 10.8 Oz(s); 306 Gram(s)
Market status On market
Date entered into DSLD Aug 22, 2017
DSLD ID 74824
Product type Amino Acid/protein
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Glutamine Chew Delicious Grape by GNC Pro Performance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chew(s)
Maximum serving Sizes:
1 Chew(s)
UPC/BARCODE
048107169961
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Added Sugars1 Gram(s)1%
Total Sugars1 Gram(s)--
L-Glutamine, Micronized2500 mg--

Other ingredients: L-Glutamine, Corn Syrup, Maltodextrin, Palm Oil, Natural Flavors, Soy Lecithin, Citric Acid, Fruit juice, Vegetable juice, Glycerin, Malic Acid, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Banned substance free

Gf Gluten free

Informed-Choice.org Trusted by sport

Formula

2500mg L-glutamine 10 calories <1g sugars

Contains: Soybeans.

General Statements

Delicious chew supports positie muscle function & immune response Superior micronized formula for maximum delivery potential

Natural flavors

Supplementation may help maintain glutamine levels that have been depleted as a result of intense exercise and may support muscle function. Glutamine is involved in protein synthesis and plays a pivotal role in the body's nitrogen balance. It serves as fuel for the immune system and maintenance of proper intestinal function.

Pro Performance quality Pro Performance L-Glutamine Chews feature our advanced micronized formula - now in a delicious and convenient chewable form.

This system micronizes large molecules into small particles into small particles, which are easier to absorb, maximizing the delivery of glutamine.

When used in conjunction with an exercise program.

Products bearing this logo have been tested for banned substances by LGC Science, Inc., a world-class anti-doping lab. Product was tested for over 145 banned substances on the 2017 World Anti-Doping Agency (WADA) Prohibited List via LGC skip lot testing protocol #ICP0307. See gnc.com for more information.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Pro Performance results

General

CODE 791307 JRG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, enjoy 1-2 chews daily.

Precautions

Contains: Soybeans.

Keep out of reach of children

Formulation

Gluten free.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

L-Glutamine Chew Delicious Grape by GNC Pro Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

L-Glutamine Chew Delicious Grape label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in L-Glutamine Chew Delicious Grape by GNC Pro Performance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Chew(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

L-Glutamine, Micronized

Interacts with
50 drugs
2500 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine, Micronized monograph & interactions

Other (inactive) ingredients: L-Glutamine, Corn Syrup, Maltodextrin, Palm Oil, Natural Flavors, Soy Lecithin, Citric Acid, Fruit juice, Vegetable juice, Glycerin, Malic Acid, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Glutamine Chew Delicious Grape by GNC Pro Performance Drug Interactions

Want to check YOUR meds against L-Glutamine Chew Delicious Grape?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine, Micronized 50

Individual Drug Interactions

The ingredients in L-Glutamine Chew Delicious Grape interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in L-Glutamine Chew Delicious Grape interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine, Micronized

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Glutamine Chew Delicious Grape with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine, Micronized1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine, Micronized full monograph & interactions
The maker

Brand information

Manufacturer and brand details for L-Glutamine Chew Delicious Grape, from the product label.

GNC Pro Performance

See all GNC Pro Performance products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

L-Glutamine Chew Delicious Grape by GNC Pro Performance: Common Questions

Does L-Glutamine Chew Delicious Grape by GNC Pro Performance interact with any medications?
Yes. Based on its ingredients, L-Glutamine Chew Delicious Grape has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Glutamine Chew Delicious Grape contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-glutamine and what does it do?
L-glutamine is an amino acid — a building block your body uses for muscle recovery, supporting your immune system, and keeping your gut lining healthy. It's one of the most abundant amino acids in your body, and supplemental doses are used to help with recovery after surgery, serious illness, or in certain medical conditions like sickle cell disease.
Will this help me recover faster after surgery?
L-glutamine is rated Possibly Effective for postoperative recovery, meaning there's some evidence it may help, but more research is needed to be sure it works for everyone. Talk with your doctor about whether it makes sense for your specific situation.
What side effects should I watch for?
Most people experience digestive symptoms — bloating, gas, constipation, diarrhea, nausea, or stomach pain — especially at higher doses. Headache and muscle pain have also been reported. These usually settle down if you lower the dose, and serious side effects are rare in healthy adults.
Is it safe to take while pregnant or breastfeeding?
L-glutamine is rated Likely Safe in pregnancy. For breastfeeding, there isn't enough safety data, so talk with your doctor or pharmacist before using this supplement while nursing.
Who should be careful with this product?
If you have kidney or liver disease, use this only under medical supervision. If you take seizure medications, check with your doctor or pharmacist first — glutamine may theoretically interfere with how well they work.
Does this chew have a lot of added sugar?
The product facts don't include a nutrition label breakdown, so we can't tell you the exact sugar content. It does contain corn syrup and sucralose as sweeteners — you can check the product label on the bottle or contact GNC directly for specific carbohydrate and sugar numbers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Glutamine Chew Delicious Grape is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Glutamine Chew Delicious Grape label
Go deeper

The Full Monographs Behind L-Glutamine Chew Delicious Grape’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

L-Glutamine Chew Delicious Grape's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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