Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Tulsi Red Mango Ingredients & Drug Interactions

by Organic India

Tulsi Red Mango label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tulsi Red Mango against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tulsi Red Mango is a dietary supplement by Organic India with 3 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep and relaxation, digestive upset.Based on those ingredients, 1,113 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chamomile, organic Rooibos, organic Tulsi (Holy Basil) Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Tulsi Red Mango by Organic India

Ask about any prescription or over-the-counter medication and we check it for interactions with Tulsi Red Mango by Organic India — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tulsi Red Mango by Organic India

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Organic Blend” is a proprietary blend — the label gives one combined amount (1.90 Gram(s)) without saying how much of each component you get.
  • “organic Tulsi (Holy Basil) Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This blend contains 5 ingredients. The active ones are organic rooibos (a caffeine-free herbal tea), Krishna tulsi, Vana tulsi, and Rama tulsi—three varieties of holy basil traditionally used in Ayurvedic practice.

Chamomile rounds out the blend. The only inactive ingredient listed is organic mango flavor.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Stress relief and immune system support.
  • We looked for evidence on: Stress, Anxiety, Generalized anxiety disorder (GAD), Respiratory tract infections, Adaptogenic support, Energy balance — and 1 related terms.
  • The closest evidence on file: Rooibos is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: German Chamomile is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Generalized anxiety disorder (GAD).
  • Also on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD), Respiratory tract infections, Stress.

The evidence we hold doesn't establish that either rooibos or any of the tulsi varieties work for their commonly promoted uses. For rooibos, the data rates age-related cognitive decline, hay fever, anxiety, cancer, heart disease, and diabetes as having insufficient reliable evidence.

The same applies to all three tulsi varieties for generalized anxiety, asthma, headache, respiratory infections, dental plaque, and diabetes. This doesn't mean they don't work—just that we don't have the data to confirm it.

The evidence, ingredient by ingredient German Chamomile Rooibos Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rooibos is generally well tolerated when used as a beverage, though concentrated extracts haven't been studied enough to call safe. Very large amounts consumed over a long time might, in rare cases, cause liver issues; one case report describes a man who drank 10 cups daily for over a year and developed liver problems and low platelet counts.

The tulsi varieties are generally well tolerated short-term, but long-term safety data are limited. A small number of trial participants experienced nausea or loose stools.

Pregnancy safety is a concern—animal data raise concerns for holy basil, and the safety data advise against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient German Chamomile Rooibos Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Rooibos, German Chamomile, Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,114 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any blood pressure medications (ACE inhibitors), cholesterol drugs like atorvastatin, blood thinners or antiplatelet medications, diabetes drugs, and any medication processed by your liver's CYP2C19, CYP1A2, CYP2D6, CYP2C9, or CYP3A4 pathways. If you take pentobarbital or other sedatives, flag those too.

Use the search tool on this page with your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a pleasant herbal tea blend, but it's not inert as far as medications go. If you take any prescription drugs, especially blood pressure meds, cholesterol drugs, blood thinners, diabetes medications, or sedatives, check them against the tool below before making this a regular habit.

Pregnant or breastfeeding? Skip it and talk to your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tulsi Red Mango, straight from the product label.

Brand Organic India
Barcode (UPC) 801541500147
Net contents 1.21 Oz(s); 34.2 Gram(s); 18 INFUSION BAGS
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50167
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic, Halal, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tulsi Red Mango by Organic India, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 infusion bag
Maximum serving Sizes:
1 infusion bag
UPC/BARCODE
801541500147
IngredientAmount% DV
Chamomile0 NP--
organic Rooibos0 NP--
Proprietary Organic Blend1.9 Gram(s)--
organic Tulsi (Holy Basil) Blend0 NP--
Krishna Tulsi0 NP--
Vana Tulsi0 NP--
Rama Tulsi0 NP--

Other ingredients: organic Mango flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Tulsi Red Mango The luscious blend of caffeine-free African Rooibos "red tea" and India's sacred Tulsi is infused with the tropical taste of India's succulent mango. Enjoy a delightfully refreshing cup and treat yourself to a moment of transformative energy.

Tulsi- A legacy of good health ~Reduces stress ~Supports the immune system ~Abundant in antioxidants ~Builds stamina ~Powerful adaptogen ~Aids digestion ~Anti aging ~Balances metabolism ~Balances energy levels ~Uplifts mood

The mind is a wonderful thing. It can take you anywhere in the universe and make you believe that whatever you see is real.-Papaji, Sri H.W.L. Poonja-

At the heart of Organic India is our commitment to be a living embodiment of love and consciousness in action. We work with thousands of small family farmers in India to cultivate tens of thousands of acres of sustainable, organic farmland. All Organic India products promote health and True Wellness and are made with loving care. The product you hold in your hands is one link in a chain of love, respect and connectedness between Mother Nature, our farmers, our company and you. By choosing Organic India you are actively participating in our mission to create a sustainable global environment, provide training and a life of dignity to our local farmers, and bring health and happiness to you.

Our Organic India family

Holy Basil

Stress-relieving & nurturing

Tulsi~Holy Basil is an herb with healing properties that relieve stress and protect the immune system.

Individually wrapped for freshness

The photo on this package is one of our farmers or a family member.

Product of India

ORGANIC INDIA is committed to responsible packaging. This carton is made from 100% recycled paperboard, with a minimum of 30% post-consumer content. Our infusion bags are made from unbleached, biodegradable fiber. Please support our environment by recycling this package.

About Tulsi Throughout India Tulsi is acclaimed as "The Queen of Herbs" and is revered as a sacred plant infused with healing powers. Traditionally grown in an earthen pot in every family home or garden, Tulsi (also known as Holy Basil) makes a delicious and nourishing herbal 'tea' abundant in a vast array of health benefits. Tulsi's life-enchancing qualities, repeatedly noted in ancient Indian scriptures dating back over 5,000 years, are now here for you to fully enjoy. Blessing and Namaste!

Formulation

Caffeine free

Certified organic

Gluten free

Certified Organic by: BIO CERT INDIA PVT LTD Bio Cert. No. ORG-COR-PC-IND-0006

Seals/Symbols

USDA ORGANIC

NON GMO Project VERIFIED nongmoproject.org

fssai Lic. No. 10012051000129

ORGANIC INDIA(TM)

USDA ORGANIC

HALAL MUMBAI INDIA HALAL COMMITTEE Registration No.:0854

OU

FDA Statement of Identity

Herbal Supplement

Formula

Kosher

Precautions

To enjoy while pregnant or nursing consult a physician before use.

General

USI1402A

Suggested/Recommended/Usage/Directions

Directions: Pour 8 oz of freshly boiled water over infusion bag in a cup. Cover and steep for 5-10 minutes or longer. Double the strength when serving iced.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tulsi Red Mango by Organic India label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tulsi Red Mango label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tulsi Red Mango by Organic India

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 infusion bag Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Organic Blend

1.9 Gram(s) per serving

Other (inactive) ingredients: Organic Mango flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tulsi Red Mango by Organic India Drug Interactions

Want to check YOUR meds against Tulsi Red Mango?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,113Drugs
1,113 Moderate

Ingredients driving the most interactions

Chamomile 960
organic Rooibos 879
organic Tulsi (Holy Basil) Blend 212

Individual Drug Interactions

The ingredients in Tulsi Red Mango interact with 1,113 drugs. Click any drug to see the details.

3 of the 3 ingredients in Tulsi Red Mango interact with drugs. Each result below shows which ingredient is responsible. Chamomile organic Rooibos organic Tulsi (Holy Basil) Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Tulsi Red Mango with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chamomile9 drug types · 960 drugs

Cns Depressants

Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.

Likelihood Possible Evidence D
Estrogens

Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.

Likelihood Possible Evidence D
Warfarin (Coumadin)

German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.

Likelihood Possible Evidence D
Chamomile full monograph & interactions

organic Rooibos7 drug types · 879 drugs

Ace Inhibitors (Aceis)

Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.

Likelihood Possible Evidence D
organic Rooibos full monograph & interactions

organic Tulsi (Holy Basil) Blend3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
organic Tulsi (Holy Basil) Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tulsi Red Mango, from the product label.

Organic India

See all Organic India products
Web Address
OrganicIndiaUSA.com
Pharmacist Counseling Corner

Tulsi Red Mango by Organic India: Common Questions

Does Tulsi Red Mango by Organic India interact with any medications?
Yes. Based on its ingredients, Tulsi Red Mango has a known interaction with 1,113 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tulsi Red Mango contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this tea safe to drink every day?
The tulsi and rooibos are generally well tolerated as a regular beverage, but long-term safety data are limited. If you drink very large amounts (like 10+ cups daily) over a long period, there's a theoretical risk of liver strain. A cup or two a day is more in line with how these teas have been used traditionally. If you have any liver concerns or take medications, ask your pharmacist first.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against it during pregnancy—animal research raises concerns about the holy basil in this blend, and human safety isn't established. For breastfeeding, there isn't enough reliable information either. Talk with your doctor or midwife before using this tea while pregnant or nursing.
What are the most common side effects?
Holy basil extract has caused nausea and loose stools in a small number of trial participants. Rooibos is generally well tolerated, though very high intakes over time could theoretically strain the liver. Most people drinking this as a tea have no issues.
Does this tea have caffeine?
The product facts we have don't list caffeine content. Rooibos is naturally caffeine-free, but we'd recommend checking the label or contacting the brand if caffeine sensitivity matters to you.
Will this help with anxiety?
The evidence we hold rates both rooibos and holy basil as having insufficient reliable evidence for anxiety. That doesn't mean they won't help—just that we don't have enough solid human research to confirm it. If you're managing anxiety, talk to your doctor about what's proven for you.
What's in the 'proprietary blend' and 'tulsi blend' on the label?
The product facts list the tulsi varieties separately as Krishna tulsi, Vana tulsi, and Rama tulsi. Those make up the tulsi blend. The proprietary blend's exact amounts aren't broken down in the data we hold, but all the active ingredients in the product are named here.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tulsi Red Mango label
Go deeper

The Full Monographs Behind Tulsi Red Mango’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

German Chamomile

Interacts with 960 drugs

German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible benefits for mild anxiety and some skin o...

Read the full German Chamomile monograph → Herb & supplement monograph

Rooibos

Interacts with 879 drugs

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early studies suggest possible benefits for he...

Read the full Rooibos monograph → Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Tulsi Red Mango's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

German Chamomile 15 references
  1. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  2. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  3. Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
  4. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
  5. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
  6. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  7. Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
  8. Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
  9. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
  10. Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
  11. Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
  12. Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
  13. Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
  14. Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
  15. Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T

See these in context on the German Chamomile monograph →

Rooibos 4 references
  1. Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
  2. Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
  3. Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
  4. Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed

See these in context on the Rooibos monograph →

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
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See these in context on the Holy Basil monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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