Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Beet Complete Black Cherry Ingredients & Drug Interactions

by ZHOU

Beet Complete Black Cherry label
See full label image
Powder Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beet Complete Black Cherry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Beet Complete Black Cherry is a dietary supplement by ZHOU with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,143 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dietary Fiber, Beet root powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Beet Complete Black Cherry by ZHOU

Ask about any prescription or over-the-counter medication and we check it for interactions with Beet Complete Black Cherry by ZHOU — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Beet Complete Black Cherry by ZHOU

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 6 active ingredients.
  • “Beet root Proprietary Blend” is a proprietary blend — the label gives one combined amount (1 Gram(s)) without saying how much of each component you get.

Beet Complete Black Cherry contains five active ingredients: grape seed extract, bilberry fruit extract, hawthorn (the flowering part of the plant), beet root powder, and tart cherry fruit concentrate. Grape seed and bilberry are antioxidant-rich plant extracts.

Hawthorn has a long history in heart health support. Beet root powder and tart cherry are added for their nutrient profiles — beet contains naturally occurring nitrates and betalains (plant pigments), while tart cherry brings anthocyanins and other polyphenols.

The powder also contains several inactive ingredients like maltodextrin (a carbohydrate), silica (an anti-caking agent), citric acid, malic acid, cherry flavoring, and stevia leaf extract for taste.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Performance, endurance, recovery, blood flow.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscle soreness, Cardiovascular disease (CVD), Coronary heart disease (CHD) — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Likely Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Beet is rated "Possibly Effective" for Athletic performance, Exercise-induced muscle soreness.
  • Also on file: Sour Cherry is rated "Possibly Effective" for Athletic performance.

The evidence for this product's ingredients is mixed. Grape seed extract is possibly effective for chronic venous insufficiency (a condition where blood pools in leg veins), but possibly ineffective for allergies, nausea from chemotherapy, and weight loss.

Bilberry's evidence is insufficient to rate it for night vision, age-related cognitive decline, eye health, heart disease, or cholesterol — there's not enough reliable data. Hawthorn likewise has insufficient evidence for angina, anxiety, heart rhythm issues, heart disease, or cognitive function.

Beet root powder is possibly effective for athletic performance and exercise-induced muscle soreness, but possibly ineffective for lung disease. Tart cherry is possibly effective for athletic performance, but we don't have enough evidence to rate it for ADHD, thinking, muscle soreness from exercise, infections, or fibromyalgia.

Overall, the strongest claims are for beet and tart cherry in athletic settings; the others lack robust proof.

The evidence, ingredient by ingredient Black Psyllium Beet Grape Bilberry Hawthorn Sour Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Grape seed extract and tart cherry are generally well tolerated in studies. Bilberry is well tolerated as a whole fruit and extracts, though concentrated supplements have limited long-term safety data.

Hawthorn is generally well tolerated when used appropriately, but rare serious reactions like organ hypersensitivity with kidney failure have been reported, and it requires medical supervision if you have a heart condition. Beet is widely eaten as food and well tolerated, though concentrated supplements lack safety data — common side effects include red or dark-colored stools, which aren't harmful.

All ingredients together, the most common minor adverse effects across the product are abdominal pain, diarrhea, nausea, headache, and joint pain — these occur in a small number of users. Rare serious effects include anaphylaxis (allergic shock) to grape skin and kidney damage from very large beet doses.

Side effects, ingredient by ingredient Black Psyllium Beet Grape Bilberry Hawthorn Sour Cherry

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Black Psyllium, Bilberry, Beet, Grape, Hawthorn.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,144 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product before you take it if you're on nitrates (for chest pain), phosphodiesterase-5 inhibitors like sildenafil, blood thinners such as warfarin or apixaban, beta-blockers, calcium channel blockers, digoxin, diabetes drugs, cyclosporine, midazolam, or any drug your liver processes through CYP1A2, CYP2D6, CYP2E1, or CYP3A4 pathways — all carry Moderate or Major severity concerns. Blood pressure drugs and antidiabetes medications warrant special attention.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product may appeal to you if you're interested in antioxidant support for athletic performance or exercise recovery, since beet and tart cherry show possibly effective evidence for those uses. If you take blood pressure medication, blood thinners, heart drugs, or drugs broken down by your liver, talk to your pharmacist before starting — hawthorn and other ingredients here can interact with those.

If you have a heart condition, get your doctor's clearance first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Complete Black Cherry, straight from the product label.

Brand ZHOU
Barcode (UPC) 669191608923
Net contents 9.24 Ounce(s); 261.9 Gram(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 249950
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Complete Black Cherry by ZHOU, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8.7 Gram(s)
Maximum serving Sizes:
8.7 Gram(s)
Servings per container
30
UPC/BARCODE
669191608923
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Sugar2 Gram(s)--
Dietary Fiber1 Gram(s)4%
Grape Seed Extract0 NP--
Bilberry fruit extract0 NP--
Hawthorne0 NP--
Beet root powder5.5 Gram(s)--
Beet root Proprietary Blend1 Gram(s)--
Tart Cherry fruit concentrate0 NP--

Other ingredients: Maltodextrin, Silica, Citric Acid, natural Cherry flavor, Malic Acid, Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Greatness by Nature

This product is packaged by weight, not by volume. Settling of contents occurs over time.

#howizhou Facebook Instagram

Formulation

All-in-one superfood blend for: Performance Endurance Recovery Blood flow

Nitric oxide superfood

Gluten free Made with Non-GMO ingredients

V Vegan

Suggested/Recommended/Usage/Directions

Suggested Use: Enjoy daily by stirring one scoop (8.7 g) into 8 oz. of water, juice, smoothie, or your favorite shake. Use only as directed.

Water Shakes

Storage

Store in a cool dry place.

Store in a cool, dry place.

Precautions

Caution: Do not exceed recommended dose.

Consult a physician before using this or any dietary supplement, especially prenant or nursing mothers, children under 18, and individuals with a known medical condition.

Consult a physician before using this or any dietary supplement, especially prenant or nursing mothers, children under 18, and individuals with a known medical condition.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Warning: Reproductive Harm - www.p65Warnings.ca.gov

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Black cherry natural flavor

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

V Vegan Lab Verified Made in the USA with Global Ingredients N03T Nitrate technology N03-T.com/patents

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beet Complete Black Cherry by ZHOU label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beet Complete Black Cherry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beet Complete Black Cherry by ZHOU

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size8.7 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

2 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Beet root powder

Interacts with
861 drugs
5.5 Gram(s) per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet root powder monograph & interactions

Beet root Proprietary Blend

Interacts with
861 drugs
1 Gram(s) per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet root Proprietary Blend monograph & interactions

Other (inactive) ingredients: Maltodextrin, Silica, Citric Acid, Natural Cherry flavor, Malic Acid, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Complete Black Cherry by ZHOU Drug Interactions

Want to check YOUR meds against Beet Complete Black Cherry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,143Drugs
14 Major 959 Moderate 1,170 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Beet root powder 861

Individual Drug Interactions

The ingredients in Beet Complete Black Cherry interact with 2,143 drugs. Click any drug to see the details.

2 of the 4 ingredients in Beet Complete Black Cherry interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Beet root powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Complete Black Cherry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Beet root powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet root powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beet Complete Black Cherry, from the product label.

ZHOU

See all ZHOU products
Name
ZHOU Nutrition Zhou, Inc.
City
Park City
State
UT
ZipCode
84098
Phone Number
1-855-700-9468
Web Address
zhounutrition.com
Pharmacist Counseling Corner

Beet Complete Black Cherry by ZHOU: Common Questions

Does Beet Complete Black Cherry by ZHOU interact with any medications?
Yes. Based on its ingredients, Beet Complete Black Cherry has a known interaction with 2,143 medications, including 14 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Complete Black Cherry contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
Grape seed extract and bilberry fruit are rated likely safe in pregnancy and lactation based on available data. Hawthorn has not enough safety information — the data advises against it during both pregnancy and breastfeeding. Beet root powder and tart cherry have no pregnancy or lactation data on file. Because this is a multi-ingredient product with mixed safety ratings, talk with your doctor or pharmacist for personalized advice before use.
What side effects should I watch for?
The most common are mild: abdominal pain, diarrhea, nausea, headache, and joint pain. Beet and bilberry may turn your stools dark colored or black, which is harmless. A small number of people report flatulence or digestive discomfort. Rare serious effects include allergic reactions and, with very high beet doses, kidney issues — but these are uncommon.
Does this actually improve athletic performance?
Beet root powder and tart cherry are both rated possibly effective for athletic performance and exercise-induced muscle soreness based on the evidence we hold. The other ingredients don't have established effectiveness for those uses.
Is this safe to take long-term?
Grape seed and beet as foods are widely eaten and well tolerated. However, concentrated supplements of most ingredients here — especially hawthorn, bilberry, and beet — have limited long-term safety data. If you plan to use this regularly, check with your pharmacist or doctor first, particularly if you have any heart or kidney conditions.
What's in this besides the active ingredients?
The powder contains maltodextrin (a carbohydrate filler), silica (to keep it dry), citric acid and malic acid (for taste), natural cherry flavoring, and stevia leaf extract (a sweetener). These are all inactive ingredients — they don't provide the main effects.
Can I take this if I'm on heart medication?
Possibly, but you must check with your pharmacist first. Hawthorn in this product can interact with blood pressure drugs, heart rate medications, and nitrates. Grape seed and other ingredients also affect how your liver processes some heart drugs. Your exact medication and dose matter — don't start without a quick conversation with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beet Complete Black Cherry is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Complete Black Cherry label
Go deeper

The Full Monographs Behind Beet Complete Black Cherry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph → Herb & supplement monograph

Grape

Interacts with 910 drugs

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...

Read the full Grape monograph → Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph → Herb & supplement monograph

Hawthorn

Interacts with 191 drugs

Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the ev...

Read the full Hawthorn monograph → Herb & supplement monograph

Sour Cherry

Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, joint and gout symptoms, and sleep. Early...

Read the full Sour Cherry monograph →
Sources

Sources & How We Checked

Beet Complete Black Cherry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 109 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Grape 34 references
  1. Kiesewetter H, Koscielny J, Kalus U, et al. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II). A randomized, double-blind, placebo-controlled trial. Arzneimittelforschung
  2. Xiao Dong S, Zhi Ping Z, Zhong Xiao W, et al. Possible enhancement of the first-pass metabolism of phenacetin by ingestion of grape juice in Chinese subjects. Br J Clin Pharmacol 1999;48:638-40. PubMed
  3. Vaswani SK, Hamilton RG, Carey RN, et al. Anaphylaxis recurrent urticaria and angioedema from grape hypersensitivity. J Allergy Clin Immunol 1998;101:S31.
  4. Chevallier A. The Encyclopedia of Medicinal Plants. London, UK: Dorling Kindersley, Ltd., 1996.
  5. Bernstein DI, Bernstein CK, Deng C, et al. Evaluation of the clinical efficacy and safety of grapeseed extract in the treatment of fall seasonal allergic rhinitis: a pilot study. Ann Allergy Asthma Immunol 2002;88:272-8.. PubMed
  6. Greenblatt DJ, von Moltke LL, Perloff ES, et al. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 2006;79:125-33. PubMed
  7. Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
  8. Ray, S. D., Parikh, H., Hickey, E., Bagchi, M., and Bagchi, D. Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation. Mol Cell B PubMed
  9. O'Byrne, D. J., Devaraj, S., Grundy, S. M., and Jialal, I. Comparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults. Am J Clin.Nutr. 2002;76(6):1367-1374.
  10. Schaefer, E., Peil, H., Ambrosetti, L., and Petrini, O. Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial. Arzneimittelforschun PubMed
  11. Nishikawa, M., Ariyoshi, N., Kotani, A., Ishii, I., Nakamura, H., Nakasa, H., Ida, M., Nakamura, H., Kimura, N., Kimura, M., Hasegawa, A., Kusu, F., Ohmori, S., Nakazawa, K., and Kitada, M. Effects of continuous ingestion of green tea or grape seed extra
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Bilberry 14 references
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Hawthorn 25 references
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Beet 14 references
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Sour Cherry 4 references
  1. Schumacher HR, Pullman-Mooar S, Gupta SR, et al. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage 2013;21(8):1035-41. PubMed
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See these in context on the Sour Cherry monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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