Chitrak Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Chitrak Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Chitrak Powder is a dietary supplement by Banyan Botanicals with 1 active ingredient. Its ingredients are commonly taken for digestive complaints and poor appetite, skin conditions and wounds (applied to the skin), joint pain and swelling.Based on those ingredients, 1,097 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ceylon Leadwort. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Chitrak Powder by Banyan Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Chitrak Powder by Banyan Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Chitrak Powder by Banyan Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Chitrak Powder is a single-ingredient product containing Ceylon leadwort. This is a traditional Ayurvedic herb that's been used for various purposes, though the only effectiveness rating in our data is for asthma, where the evidence is too limited to assess.
The product contains no inactive fillers or other ingredients—it's pure powder form.
Does it work?
Couldn't assess
Our data holds only one effectiveness rating for Ceylon leadwort: asthma. The evidence to assess its use for asthma is insufficient and unreliable, so we can't determine whether it works for that purpose.
If you're considering this product for other uses, the evidence isn't established in the data we hold.
How safe is it?
Some data gaps
Ceylon leadwort contains plumbagin, a compound that can irritate your skin and gut and may become toxic at higher doses. The safety data advises against using this product during pregnancy because it has traditionally been used to cause abortion.
There also isn't enough safety information to recommend it while breastfeeding, so it's best avoided then as well. No adverse effects from trials are documented in our data, though the safety concerns listed above are important to respect.
Meds to double-check
Moderate interaction found
Before taking Chitrak Powder, check with your doctor or pharmacist if you take any of these: blood thinners or antiplatelet drugs (bleeding risk), diabetes medications (unpredictable blood sugar effects), hormone therapy, antidepressants or other drugs that work through liver enzyme CYP2D6, muscle relaxants or other drugs metabolized by CYP1A2, pain relievers or blood pressure drugs using CYP2C9, or immunosuppressive medications. Although these interactions haven't been confirmed in people yet, the theoretical risks are significant.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.
This is a single-herb powder with documented interactions across multiple medication types. If you take any blood pressure drugs, antidepressants, blood thinners, diabetes medications, immunosuppressants, or hormone therapy, check with your doctor or pharmacist before starting.
Avoid it entirely during pregnancy and breastfeeding. Talk it over with your healthcare provider to see whether this product fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Chitrak Powder, straight from the product label.
| Brand | Banyan Botanicals |
|---|---|
| Barcode (UPC) | 618192076224 |
| Net contents | 227 Gram(s); 0.5 Pound(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2024 |
| DSLD ID | 305612 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Chitrak Powder by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Ceylon Leadwort | 0.5 Teaspoon(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
(Plumbago zeylanica) Organic Ayurvedic herbs
Chitrak (Plumbago zeylanica) is a powerful heating herb that is traditionally used to enkindle the digestive fire, support healthy metabolism, and remove natural toxins from the intestines. It is also commonly used as a primary ingredient in weight management formulas. Chitrak supports the proper function of the liver and the healthy digestion of fat and sugars. It helps energize the body naturally by promoting healthy digestion and the proper absorption and assimilation of nutrients.
Formulation
Supporting your Ayurvedic lifestyle
Non-GMO
Supports optimal weight management Supports proper function of the liver and healthy digestion of fat and sugars Strengthens the digestive fire Heating herb that supports healthy metabolism and removes natural toxins from the intestines
Certified Organic by: QAI
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
USDA Organic
Sustainably sourced Fairly traded
Suggested/Recommended/Usage/Directions
Suggested use: 1/4 to 1/2 teaspoon with warm water, once or twice daily, or as directed by your health practitioner.
Precautions
If you are pregnant, nursing, taking medications, or have a medical condition, please consult with your health care practitioner prior to the use of this product.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Banyan Botanicals was founded in 1996 with the mission to help people achieve and maintain optimal health and well-being. As an Ayurvedic lifestyle company, we specialize in products made from Ayurvedic herbs that are organically grown, sustainably sourced, fairly traded, and made in the USA. Banyan is committed to providing exceptional customer service, inspire educational content, and the highest quality Ayurvedic herbs that are safe, pure, and effective.
Illuminate your path to well-being Get your free Ayurvedic Profile at banyanbotanicals.com/illuminate
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Chitrak Powder by Banyan Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Chitrak Powder by Banyan Botanicals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container177 Amounts shown are per serving.
Ceylon Leadwort
Interacts with1,097 drugs
Ceylon Leadwort (Plumbago zeylanica) is a plant long used in Ayurvedic and other traditional medicine systems, mainly for digestion, skin problems, an...
Ceylon Leadwort monograph & interactionsChitrak Powder by Banyan Botanicals Drug Interactions
HelloPharmacist Interaction Report
Chitrak Powder by Banyan Botanicals contains Ceylon leadwort, which has documented interactions with multiple medication types.
The ingredient contains plumbagin, a compound that inhibits several liver enzymes (CYP2D6, CYP1A2, CYP2C9, and CYP3A4) in lab studies, though these interactions haven't yet been observed in people. Theoretically, Ceylon leadwort could raise the blood levels of drugs broken down by these pathways, potentially making them stronger than intended.
These enzyme interactions are all rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Additionally, Ceylon leadwort may interfere with hormone therapy (estrogens), blood thinners and antiplatelet drugs (with a theoretical risk of increased bleeding), and immunosuppressive medications used after organ transplant. It may also raise or lower blood sugar levels unpredictably if you take diabetes medications.
All of these are Moderate-severity concerns in the data.
Although these interactions come from lab research rather than confirmed human cases, they're significant enough that you'll want to check any prescription medications you take before starting this product. Altogether, these interactions span 1,098 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Chitrak Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Chitrak Powder interact with 1,097 drugs. Click any drug to see the details.
1 of the 1 ingredient in Chitrak Powder interact with drugs. Each result below shows which ingredient is responsible. Ceylon Leadwort
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortImmunosuppressants Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has demonstrated immunosuppressant activity in animal research.
Read the full Ceylon Leadwort + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
There is some concern that Ceylon leadwort might potentiate the effects of anticoagulant and antiplatelet drugs and possibly increase the risk of bleeding.
Read the full Ceylon Leadwort + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2C9 (CYP2C9) in vitro.
Read the full Ceylon Leadwort + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortAntidiabetes Drugs Moderate
Interaction Summary
Ceylon leadwort root extract has been shown to both increase and decrease blood glucose levels in animal research.
Read the full Ceylon Leadwort + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
There is some concern that Ceylon leadwort might potentiate the effects of anticoagulant and antiplatelet drugs and possibly increase the risk of bleeding.
Read the full Ceylon Leadwort + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 1A2 (CYP1A2) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
There is some concern that Ceylon leadwort might potentiate the effects of anticoagulant and antiplatelet drugs and possibly increase the risk of bleeding.
Read the full Ceylon Leadwort + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 1A2 (CYP1A2) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 1A2 (CYP1A2) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 1A2 (CYP1A2) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 1A2 (CYP1A2) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Chitrak Powder — through 1 ingredient. Tap an ingredient for the detail:
Ceylon LeadwortCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro.
Read the full Ceylon Leadwort + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Chitrak Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ceylon Leadwort
Anticoagulant/Antiplatelet Drugs
There is some concern that Ceylon leadwort might potentiate the effects of anticoagulant and antiplatelet drugs and possibly increase the risk of bleeding. Ceylon leadwort root extract has been shown to decrease platelet adhesion and prolong bleeding in animals. However, this effect has not yet been demonstrated in humans. Until more is known, use cautiously in patients taking anticoagulant or antiplatelet drugs. Some of these drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Antidiabetes Drugs
Ceylon leadwort root extract has been shown to both increase and decrease blood glucose levels in animal research. This effect has not yet been demonstrated in humans. Theoretically, Ceylon leadwort might reduce or potentiate the effects of antidiabetes drugs. Monitor blood glucose levels closely. Medication dose adjustments may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 1A2 (CYP1A2) in vitro. So far, this interaction has not been reported in humans. Theoretically, Ceylon leadwort might increase the levels of drugs metabolized by CYP1A2. Some substrates of CYP1A2 include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), and others.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2B6 (CYP2B6) in vitro. So far, this interaction has not been reported in humans. Theoretically, Ceylon leadwort might increase the levels of drugs metabolized by CYP2B6. Drugs that are metabolized by CYP2B6 include ketamine (Ketalar), phenobarbital, orphenadrine (Norflex), secobarbital (Seconal), and dexamethasone (Decadron).
Cytochrome P450 2C9 (Cyp2C9) Substrates
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2C9 (CYP2C9) in vitro. So far, this interaction has not been reported in humans. Theoretically, Ceylon leadwort might increase the levels of drugs metabolized by CYP2C9. Drugs that are metabolized by CYP2C9 include celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), and S-warfarin (Coumadin).
Cytochrome P450 2D6 (Cyp2D6) Substrates
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro. So far, this interaction has not been reported in humans. Theoretically, Ceylon leadwort might increase the levels of drugs metabolized by CYP2D6. Some drugs metabolized by CYP2D6 include amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), fluoxetine (Prozac), ondansetron (Zofran), tramadol (Ultram), and others.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2E1 (CYP2E1) in vitro. So far, this interaction has not been reported in humans. Theoretically, Ceylon leadwort might increase the levels of drugs metabolized by CYP2E1. Some drugs metabolized by CYP2E1 include acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, and anesthetics such as enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), methoxyflurane (Penthrane).
Cytochrome P450 3A4 (Cyp3A4) Substrates
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro. So far, this interaction has not been reported in humans. Theoretically, Ceylon leadwort might increase the levels of drugs metabolized by CYP3A4. Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and numerous others.
Estrogens
Laboratory research suggests that Ceylon leadwort root extract has anti-estrogenic activity. Theoretically, Ceylon leadwort may interfere with hormone therapy.
Immunosuppressants
Plumbagin, a constituent of Ceylon leadwort, has demonstrated immunosuppressant activity in animal research. Theoretically, Ceylon leadwort might interfere with immunosuppressive therapy. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
Brand information
Manufacturer and brand details for Chitrak Powder, from the product label.
Banyan Botanicals
See all Banyan Botanicals products- Name
- Banyan Botanicals
- City
- Albuquerque
- State
- NM
- ZipCode
- 87113
- Phone Number
- 1-800-953-6424
- Web Address
- banyanbotanicals.com
Chitrak Powder by Banyan Botanicals: Common Questions
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Sources & How We Checked
Chitrak Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
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The 10 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ceylon Leadwort 10 references
- Mandavkar, YD, Jalalpure, SS. A comprehensive review on Plumbago zeylanica Linn. African J. Pharmacy and Pharmacology. 2011;5(25):2738-2747. DOI
- Kumar SS, Shanmugasundaram KR. Amrita Bindu-an antioxidant inducer therapy in asthma children. J. Ethnopharmacol. 2004;90:105-114. PubMed
- Sandeep G, Dheeraj A, Sharma NK, Jhade D, Bharti A. Effect of plumbagin free alcohol extract of Plumbago zeylanica Linn. root on reproductive system of female Wistar rats. Asian Pac J Trop Med. 2011 Dec;4(12):978-84. PubMed
- Vijayakumar R, Senthilvelan M, Ravindran R, Devi RS. Plumbago zeylanica action on blood coagulation profile with and without blood volume reduction. Vascul Pharmacol. 2006 Aug;45(2):86-90. PubMed
- Olagunju JA, Jobi AA, Oyedapo OO. An investigation into the biochemical basis of the observed hyperglycaemia in rats treated with ethanol root extract of plumbago zeylanica. Phytother Res. 1999 Jun;13(4):346-8.
- Chen A, Zhou X, Tang S, Liu M, Wang X. Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach. Sci Rep. 2016 Jun 22;6:28482. PubMed
- Sunil C, Duraipandiyan V, Agastian P, Ignacimuthu S. Antidiabetic effect of plumbagin isolated from Plumbago zeylanica L. root and its effect on GLUT4 translocation in streptozotocin-induced diabetic rats. Food Chem Toxicol. 2012 Dec;50(12):4356-63. PubMed
- Checker R, Sharma D, Sandur SK, Khanam S, Poduval TB. Anti-inflammatory effects of plumbagin are mediated by inhibition of NF-kappaB activation in lymphocytes. Int Immunopharmacol. 2009 Jul;9(7-8):949-58. PubMed
- Jia Y, Jing J, Bai Y, Li Z, Liu L, Luo J, Liu M, Chen H. Amelioration of experimental autoimmune encephalomyelitis by plumbagin through down-regulation of JAK-STAT and NF-?B signaling pathways. PLoS One. 2011;6(10):e27006. PubMed
- Poosarla A, D N R, Athota RR, Sunkara VG. Modulation of T cell proliferation and cytokine response by Plumbagin, extracted from Plumbago zeylanica in collagen induced arthritis. BMC Complement Altern Med. 2011 Nov 16;11:114. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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