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Dietary supplement

Chlorophyll Ingredients & Drug Interactions

by Nature's Sunshine

Chlorophyll label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chlorophyll against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chlorophyll is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for body and breath odor control, wound and skin care, internal deodorant for ostomy or incontinence.Based on those ingredients, 335 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyllin Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chlorophyll by Nature's Sunshine

Ask about any prescription or over-the-counter medication and we check it for interactions with Chlorophyll by Nature's Sunshine — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Chlorophyll by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: chlorophyllin complex, a semi-synthetic form of chlorophyll (the pigment that makes plants green). The capsule also holds soybean oil, gelatin, glycerin, and water as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Chlorophyllin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: digestive tract detoxifier and intestinal support.
  • We looked for evidence on: Body odor, Fecal odor, Flatulence, Wound healing, digestive detoxification, phase II enzyme support.
  • The closest evidence on file: Chlorophyllin is rated "Insufficient Reliable Evidence To Rate" for Flatulence (Natural Medicines).
  • Also on file: Chlorophyllin is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Body odor, Fecal odor.

The evidence for chlorophyll's effectiveness is mixed. For urinary odor, it's rated possibly ineffective — meaning the data doesn't support that it works.

For acne, cancer, constipation, flatulence, and low white blood cell count (leukopenia), we don't have enough reliable evidence to rate it either way.

The evidence, ingredient by ingredient Chlorophyllin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorophyllin is generally well tolerated in the short term, but quality evidence and long-term safety data are limited. The main concern is photosensitization — oral chlorophyll has been reported to cause increased sun sensitivity and, in rare case reports, a condition similar to pseudoporphyria (painful blisters on sun-exposed skin, particularly the hands).

Topical chlorophyll cream has also caused dermatitis in some cases. During pregnancy, there isn't enough reliable safety data, so it's best to avoid use.

Safety while breastfeeding is also unknown, so avoidance is the safer choice. Talk with your doctor or pharmacist before taking this product if you're pregnant, breastfeeding, or planning either.

Side effects, ingredient by ingredient Chlorophyllin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorophyllin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 335 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, double-check with your doctor or pharmacist if you take any photosensitizing drugs — medications that make your skin more sensitive to sunlight. Altogether, these interactions span 335 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Chlorophyll may be worth considering if you're curious about traditional herbal uses, but the evidence for most claimed benefits isn't established. If you take any medication that increases sun sensitivity, check with your doctor or pharmacist before adding this product — the combination could raise your risk of sunburn or skin reaction.

Avoid it during pregnancy and breastfeeding unless your healthcare provider advises otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorophyll, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904016903
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 278057
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorophyll by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
099904016903
IngredientAmount% DV
Chlorophyllin Complex100 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

New look! Same great product

We source the world's purest ingredients, no matter where they are grown, to ensure the active nutrients are delivered just as nature intended.

Formulation

Supports detoxification Intestinal system support

Digestive tract detoxifier Upregulates Phase II enzymes

Guaranteed pure

Precautions

Do not use if inner seal is missing or damaged.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Natures Sunshine Herbal experts since 1972

Suggested/Recommended/Usage/Directions

Recommended Use: Take 2 softgels daily with a meal.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chlorophyll by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chlorophyll label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chlorophyll by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Chlorophyllin Complex

Interacts with
335 drugs
100 mg per serving

Chlorophyllin is a water-soluble, semi-synthetic form of chlorophyll most often used to help control body and fecal odor and to support wound healing....

Chlorophyllin Complex monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorophyll by Nature's Sunshine Drug Interactions

Want to check YOUR meds against Chlorophyll?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
335Drugs
335 Moderate

Ingredients driving the most interactions

Chlorophyllin Complex 335

Individual Drug Interactions

The ingredients in Chlorophyll interact with 335 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chlorophyll interact with drugs. Each result below shows which ingredient is responsible. Chlorophyllin Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorophyll with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorophyllin Complex1 drug type · 335 drugs

Photosensitizing Drugs

Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Chlorophyllin is a semi-synthetic derivative of chlorophyll. Chlorophyll has been reported to cause photosensitization. Orally, chlorophyll has also been associated with the development of pseudoporphyria in multiple case reports.

Likelihood Probable Evidence B
Chlorophyllin Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chlorophyll, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

Chlorophyll by Nature's Sunshine: Common Questions

Does Chlorophyll by Nature's Sunshine interact with any medications?
Yes. Based on its ingredients, Chlorophyll has a known interaction with 335 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorophyll contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's chlorophyllin, and how is it different from regular chlorophyll?
Chlorophyllin is a semi-synthetic version of chlorophyll, the green pigment in plants. It's been modified to make it easier for your body to use, but it may carry some of the same risks as natural chlorophyll — including increased sun sensitivity.
Can I take this if I'm on antibiotics or other sun-sensitizing medications?
Not without checking first. Chlorophyll may add to the sun-sensitivity effects of certain antibiotics and other photosensitizing drugs, raising your risk of severe sunburn or skin reaction. Talk with your doctor or pharmacist before combining them.
Is it safe to take long-term?
Short-term use appears generally well tolerated, but we don't have quality evidence or long-term safety data. If you're thinking of taking it regularly, discuss that with your doctor or pharmacist.
Does chlorophyll really help with body odor?
For urinary odor specifically, the evidence says it's possibly ineffective — meaning it doesn't appear to work for that purpose based on available data.
Can I take this while pregnant or breastfeeding?
No — there isn't enough reliable safety data during pregnancy, so avoidance is the safer choice. Safety while breastfeeding is also unknown. Talk with your doctor or pharmacist if you're pregnant, breastfeeding, or planning either before starting this product.
What side effects should I watch for?
The main concern is photosensitization — increased sun sensitivity that can lead to severe sunburn. In rare cases, oral chlorophyll has been linked to pseudoporphyria, a condition causing painful, easily traumatized blisters on sun-exposed skin, especially the hands. Stop and talk with your doctor if you develop these symptoms.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chlorophyll is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorophyll label
Go deeper

The Full Monographs Behind Chlorophyll’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorophyllin

Interacts with 335 drugs

Chlorophyllin is a water-soluble, semi-synthetic form of chlorophyll most often used to help control body and fecal odor and to support wound healing. The best evidence is for its use as a d...

Read the full Chlorophyllin monograph →
Sources

Sources & How We Checked

Chlorophyll's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorophyllin 6 references
  1. Nahata MC, Slencsak CA, Kamp J. Effect of chlorophyllin on urinary odor in incontinent geriatric patients. Drug Intell Clin Pharm 1983;17:732-4. PubMed
  2. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  3. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed
  6. Tomankova K, Kejlova K, Binder S, et al. In vitro cytotoxicity and phototoxicity study of cosmetics colorants. Toxicol In Vitro. 2011 Sep;25(6):1242-50. PubMed

See these in context on the Chlorophyllin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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