Thioridazine
117 interactions 6 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
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Thioridazine Acetaminophen And Codeine Capital® & Codeine Explained Reduced codeine and morphine exposure, increased risk of paralytic ileus and an increased risk of respiratory and CNS depression Details Thioridazine Buprenorphine Belbuca Explained Reduced buprenorphine exposure, reduced efficacy of buprenorphine, an increased risk of QT interval prolongation, an increased ris... Details Thioridazine Atogepant Qulipta Reduced atogepant exposure Details Thioridazine Avapritinib Ayvakit Reduced avapritinib exposure and reduced efficacy of avapritinib Details Thioridazine Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Thioridazine Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Thioridazine Abiraterone Abirtega Increased thioridazine exposure Details Thioridazine Aficamten Reduced aficamten exposure and reduced efficacy of aficamten Details Thioridazine Amlodipine Amvaz® Reduced amLODIPine exposure Details Thioridazine Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Thioridazine Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Thioridazine Cabozantinib Cabometyx Reduced cabozantinib exposure and reduced efficacy of cabozantinib Details Thioridazine Cabozantinib (Thyroid Cancer) Cabometyx Reduced cabozantinib exposure and reduced efficacy of cabozantinib Details Thioridazine Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Thioridazine Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Thioridazine Cyclosporine Injection Atopica Reduced cycloSPORINE exposure Details Thioridazine Cyclosporine Ophthalmic Cequa Reduced cycloSPORINE exposure Details Thioridazine Dacomitinib Vizimpro Increased exposure of the CYP2D6 substrate Details Thioridazine Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Thioridazine Diazepam Rectal Diastat Increased risk of CNS depression Details Thioridazine Doravirine Pifeltro Reduced doravirine exposure and reduced efficacy of doravirine Details Thioridazine Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Thioridazine Erdafitinib Balversa Reduced erdafitinib exposure Details Thioridazine Esketamine Nasal Spray Spravato Increased risk of sedation Details Thioridazine Fentanyl Transdermal Patch Duragesic® Reduced fentaNYL exposure, reduced efficacy of fentaNYL, an increased risk of urinary retention and/or severe constipation, which... Details Thioridazine Finerenone Kerendia Reduced finerenone exposure and reduced efficacy of finerenone Details Thioridazine Glucagon Injection Baqsimi Increased risk of gastrointestinal side effects Details Thioridazine Glucagon Injection / Solution Baqsimi Increased risk of gastrointestinal side effects Details Thioridazine Glucagon Nasal Powder Baqsimi Increased risk of gastrointestinal side effects Details Thioridazine Glycopyrronium Topical Cuvposa® An increased risk of anticholinergic side effects Details Thioridazine Hydromorphone Injection Dilaudid Increased risk of paralytic ileus and an increased risk of respiratory and CNS depression Details Thioridazine Hydromorphone Rectal available generically Increased risk of paralytic ileus and an increased risk of respiratory and CNS depression Details Thioridazine Lacosamide Injection Motpoly An increased risk of CNS depression Details Thioridazine Lenacapavir Injection Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir Details Thioridazine Lenacapavir Oral Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir Details Thioridazine Leniolisib Joenja Reduced leniolisib exposure and reduced efficacy of leniolisib Details Thioridazine Letermovir Injection Prevymis Reduced letermovir exposure and reduced efficacy of letermovir Details Thioridazine Levodopa Oral Inhalation Inbrija Reduce efficacy of levodopa (foslevodopa), an increased risk of exacerbating psychosis [or symptoms of Parkinson's disease: delusi... Details Thioridazine Levonorgestrel After banger Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Thioridazine Levonorgestrel Intrauterine System Kyleena Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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