Drug & supplement interaction

Moringa + Insulin Degludec

Insulin Degludec brand name: Tresiba.

Minor Interaction
Medically reviewed by · Updated September 2026
The bottom line Minor

Moringa has a minor interaction with Insulin Degludec. Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.

Read the full interaction report
SeverityMinor
LikelihoodPossible
EvidenceB
What do Severity, Likelihood & Evidence mean?
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Interaction report

Moringa and Insulin Degludec

Here is the interaction we found between these two, with the evidence behind it.

Minor

ANTIDIABETES DRUGS

Why this applies to Insulin Degludec

Insulin Degludec falls under ANTIDIABETES DRUGS — the group Moringa interacts with.

Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.
Severity Minor Likelihood Possible Evidence B

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist with moringa and your Tresiba (insulin degludec): moringa may have a mild blood sugar lowering effect of its own. When you stack that on top of a long-acting insulin that's already doing the heavy lifting, the two could add together and nudge your numbers a little lower than expected. In theory, that raises the chance of a low blood sugar episode (shakiness, sweating, dizziness, confusion).

That said, I want to keep this in perspective. The strong blood sugar drops were mostly seen in animal studies, and human results have been all over the map, so this is a fairly weak, theoretical concern. Food amounts of moringa leaf are unlikely to cause trouble. If you're using concentrated supplement doses, just check your sugars more closely at first and loop in your pharmacist or doctor before changing anything.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
  2. Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
  3. Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
  4. Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
  5. William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
  6. Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Moringa Also Interacts With Other Medications

Moringa has 717 moderate, 151 minor known drug interactions in our database — the Insulin Degludec one above is one of them. If you take anything else, check it against the full list below.

Moderate 717 Minor 151 No known interaction 1,962 (incl. Insulin Degludec)
Taking anything else?

Check Another of Your Medications Against Moringa

Covers the 2,830 medications we’ve checked against Moringa. Pick one to open its full report.

From our Q&A

Questions About Moringa or Insulin Degludec

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Moringa or Insulin Degludec, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Insulin Degludec

This page covers Moringa only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Insulin Degludec page lists 239 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).

By severity: 1 major · 208 moderate · 30 minor.

From our pharmacist’s overview on the Insulin Degludec page

“Insulin degludec (Tresiba) is a long-acting insulin meant to hold blood sugar steady around the clock, which means anything else that pushes glucose down can push it too far. That is the story for nearly all 239 ingredients on this page, and the list warrants genuine caution.”

Reviewed by 2 · Jul 18, 2026

Open the Insulin Degludec interaction page

One more smart check

Taking Moringa as Part of a Dietary Supplement Product? Check It for Interactions

We hold 738 real supplement products containing Moringa, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Moringa. Your product may carry other ingredients that interact with Insulin Degludec too, on top of Moringa — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Moringa and Insulin Degludec Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Moringa
Top 25%

#200 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Insulin Degludec
Top half

#1,158 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Moringa

What is Moringa?

  • Nutritional supplement
  • Blood sugar support
  • Cholesterol support
  • Inflammation
  • Skin conditions

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common. Early research hints at possible benefits for blood sugar, cholesterol, and inflammation, but the human evidence is limited and not strong enough to recommend it as a treatment. Talk with your pharmacist or doctor before using moringa, especially if you are pregnant, breastfeeding, or taking medications.

Read the full Moringa monograph & all interactions
Medication

About Insulin Degludec (rDNA Origin) Injection

What Is Insulin Degludec (rDNA Origin) Injection Used For?

Brand name: Tresiba

Insulin degludec (brand name Tresiba) is used to improve blood sugar (glucose) control in adults and children 1 year of age and older who have diabetes mellitus — including both type 1 and type 2 diabetes.

It is not recommended for treating diabetic ketoacidosis (a dangerous complication of diabetes that requires a different type of treatment). In people with type 1 diabetes, insulin degludec must always be used together with a short-acting insulin.

See full Insulin Degludec (rDNA Origin) Injection drug information
Keep checking

Other Drugs & Moringa

Browse every other medication we’ve checked against Moringa — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
717Moderate
151Minor
1,961No known interaction
717 Moderate 151 Minor 1,961 No interaction
Moderate

717 interactions

Showing 60 of 717 moderate interactions — see all 717 on the Moringa page.

Minor

151 interactions

Showing 60 of 151 minor interactions — see all 151 on the Moringa page.

No interaction 1,961 drugs checked — show the list

We also checked Moringa against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,961 medications checked with no known interaction — see the full Moringa list.

See the full Moringa interactions page
See every supplement checked against Insulin Degludec, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Moringa monograph › Uses, safety, and every drug interaction in one place Insulin Degludec supplement interactions › Every supplement checked against Insulin Degludec, ranked by severity Insulin Degludec (rDNA Origin) Injection drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Moringa and Insulin Degludec Together: Common Questions

Can you take Moringa with Insulin Degludec?
There is only a minor interaction, which is usually not serious. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Moringa and Insulin Degludec interaction?
We rate it Minor. This interaction is generally not clinically significant, but it remains worth noting and discussing with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Insulin Degludec and Moringa?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.