Medication interaction hub

What Supplements Interact with Ombitasvir, Paritaprevir Ritonavir?

Ombitasvir, Paritaprevir Ritonavir brand name: Technivie. Every interaction below applies to the brands too.

154 Interactions 3 Major 113 Moderate 38 Minor
Curated & coded by · Clinical Pharmacist · Updated September 19, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Ombitasvir, Paritaprevir Ritonavir? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Ombitasvir, Paritaprevir Ritonavir against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Technivie (ombitasvir, paritaprevir, and ritonavir) treats hepatitis C, and because a cure depends on holding steady drug levels for the whole course, this list warrants genuine care. Most of the 154 ingredients on file touch the CYP3A4 enzyme pathway, meaning they can push the drug's blood levels up or down. Three rate major: grapefruit drives levels up, St. John's wort strips them down, and activated charcoal can keep the pills from being absorbed at all.

Of the remaining 113 moderate and 38 minor entries, most nudge that same enzyme more gently or act on P-glycoprotein, a transporter that controls how much drug crosses the gut wall. A smaller cluster of bulky fibers and minerals can blunt absorption of the tablets themselves. A stretch of low drug levels mid-treatment can mean failure or resistance, so run supplements past your pharmacist before you swallow the first capsule.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 113 Minor 38 No known interaction 1,298

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Ombitasvir, Paritaprevir Ritonavir: Top Interactions at a Glance

The most significant Ombitasvir, Paritaprevir Ritonavir supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 154 interacting ingredients — plus 1,298 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Ombitasvir, Paritaprevir Ritonavir + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Grapefruit + Ombitasvir, Paritaprevir Ritonaviri

Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Read the full interaction Major Likelihood Probable Activated Charcoal + Ombitasvir, Paritaprevir Ritonaviri

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable St. John's Wort + Ombitasvir, Paritaprevir Ritonaviri

St.

Read the full interaction
The complete list

Every Supplement Checked Against Ombitasvir, Paritaprevir Ritonavir

All 1,452 ingredients in our database, ranked by severity — 154 with a Ombitasvir, Paritaprevir Ritonavir interaction on file and 1,298 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Ombitasvir, Paritaprevir Ritonavir?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Echinacea with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.

Full Echinacea + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Hibiscus Sabdariffa with Ombitasvir, Paritaprevir Ritonavir?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Hibiscus sabdariffa extract might reduce the metabolism of CYP3A4 substrates.

Full Hibiscus Sabdariffa + Ombitasvir, Paritaprevir Ritonavir answer

Can you take European Mandrake with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Gamma-hydroxybutyrate (ghb) with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use of ritonavir and GHB may increase the risk of serious adverse effects.

Full Gamma-hydroxybutyrate (ghb) + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Garlic with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.

Full Garlic + Ombitasvir, Paritaprevir Ritonavir answer

Can you take German Chamomile with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.

Full German Chamomile + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Ginger with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Ginger might increase or decrease the levels of CYP3A4 substrates.

Full Ginger + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Ginkgo with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, ginkgo might decrease levels of drugs metabolized by CYP3A4.

Full Ginkgo + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Goji with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.

Full Goji + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Goldthread with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme.

Full Goldthread + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Grape with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.

Full Grape + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Green Tea with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Green tea might increase the levels and adverse effects of P-glycoprotein (P-gp) substrates.

Full Green Tea + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Guar Gum with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.

Full Guar Gum + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Gum Arabic with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.

Full Gum Arabic + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Hesperidin with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hesperidin might inhibit P-glycoprotein-mediated drug efflux and potentially increase levels of drugs that are substrates of...

Full Hesperidin + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Higenamine with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, higenamine might increase the levels and clinical effects drugs metabolized by CYP3A4.

Full Higenamine + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Horny Goat Weed with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.

Full Horny Goat Weed + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Hu Zhang with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.

Full Hu Zhang + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Indian Long Pepper with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.

Full Indian Long Pepper + Ombitasvir, Paritaprevir Ritonavir answer

Can you take Kava with Ombitasvir, Paritaprevir Ritonavir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. It is unclear if kava inhibits P-glycoprotein (P-gp); research is conflicting.

Full Kava + Ombitasvir, Paritaprevir Ritonavir answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Ombitasvir, Paritaprevir Ritonavir is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Ombitasvir, Paritaprevir Ritonavir, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Ombitasvir, Paritaprevir Ritonavir sits in 7 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Ombitasvir, Paritaprevir Ritonavir through this category.

P-Glycoprotein Substrates 37 ingredients

A drug-transport group: these medications are moved in and out of cells by the P-glycoprotein pump. Supplements that affect the pump can change how much of the drug is absorbed or kept in the body.

37 of the supplement ingredients on this page reach Ombitasvir, Paritaprevir Ritonavir through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Ombitasvir, Paritaprevir Ritonavir through this category.

Cytochrome P450 3A4 (Cyp3A4) Inhibitors 13 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

13 of the supplement ingredients on this page reach Ombitasvir, Paritaprevir Ritonavir through this category.

Ritonavir (Norvir) 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Ombitasvir, Paritaprevir Ritonavir through this category.

Lopinavir/Ritonavir (Kaletra) 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Ombitasvir, Paritaprevir Ritonavir through this category.

Nirmatrelvir/Ritonavir (Paxlovid) 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Ombitasvir, Paritaprevir Ritonavir through this category.

About Ombitasvir, Paritaprevir Ritonavir

Ombitasvir, Paritaprevir Ritonavir is a prescription medication also sold under the brand name Technivie. Because supplements and herbal products can change how medications work — or how strongly — every ingredient on this page has been checked against it in our interaction database.

Generic name: Ombitasvir, Paritaprevir Ritonavir  ·  Brand name: Technivie.

See the full Ombitasvir, Paritaprevir, and Ritonavir drug information
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Take a Supplement Product? Check the Whole Bottle Against Ombitasvir, Paritaprevir Ritonavir

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Ombitasvir, Paritaprevir Ritonavir.

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Pharmacist Counseling Corner

Ombitasvir, Paritaprevir Ritonavir & Supplements: Common Questions

What supplements interact with Ombitasvir, Paritaprevir Ritonavir?
More than you might expect — 154 in total, though they are far from equal: 3 are rated major, 113 moderate, and 38 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Grapefruit, Activated Charcoal, St. John's Wort.
Which Ombitasvir, Paritaprevir Ritonavir supplement interactions are the most serious?
The 3 major-rated combinations — led by Grapefruit, Activated Charcoal and St. John's Wort — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Ombitasvir, Paritaprevir Ritonavir?
Usually yes — most people on Ombitasvir, Paritaprevir Ritonavir can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Technivie have the same supplement interactions as Ombitasvir, Paritaprevir Ritonavir?
Yes — Technivie all contain Ombitasvir, Paritaprevir Ritonavir, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Ombitasvir, Paritaprevir Ritonavir and my other medications?
This page covers Ombitasvir, Paritaprevir Ritonavir against supplements and herbal ingredients. Checking Ombitasvir, Paritaprevir Ritonavir against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Ombitasvir, Paritaprevir, and Ritonavir drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 19, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.