Medication interaction hub

What Supplements Interact with Retapamulin?

Retapamulin brand names: Altabax, Altargo. Every interaction below applies to the brands too.

81 Interactions 2 Major 71 Moderate 8 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Retapamulin? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Retapamulin against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

81 supplements and herbal ingredients have interactions with Retapamulin on file in the HelloPharmacist interaction database — 2 rated major, 71 moderate, and 8 minor. The most serious involve Para-aminobenzoic Acid (paba) and Oleander.

Our assessment: with 2 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Retapamulin.

Major 2 Moderate 71 Minor 8 No known interaction 1,371

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Retapamulin: Top Interactions at a Glance

The most significant Retapamulin supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 81 interacting ingredients — plus 1,371 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Retapamulin + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Para-aminobenzoic Acid (paba) + Retapamulini

Theoretically, concomitant use of PABA and sulfonamide antibiotics inhibits the antibacterial effects of sulfonamide.

Read the full interaction Major Likelihood Probable Oleander + Retapamulini

Theoretically, macrolide antibiotics may increase the risk of oleander toxicity.

Read the full interaction
The complete list

Every Supplement Checked Against Retapamulin

All 1,452 ingredients in our database, ranked by severity — 81 with a Retapamulin interaction on file and 1,371 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Retapamulin?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Bromelain with Retapamulin?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, bromelain might increase levels of tetracycline antibiotics.

Full Bromelain + Retapamulin answer

Can you take Guarana with Retapamulin?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Guarana + Retapamulin answer

Can you take Ilex Guayusa with Retapamulin?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Ilex Guayusa + Retapamulin answer

Can you take Oolong Tea with Retapamulin?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine in oolong tea.

Full Oolong Tea + Retapamulin answer

Can you take Pu-erh Tea with Retapamulin?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Pu-erh Tea + Retapamulin answer

Can you take Soy with Retapamulin?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, antibiotics may decrease the activity of soy isoflavones.

Full Soy + Retapamulin answer

Can you take Para-aminobenzoic Acid (paba) with Retapamulin?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use of PABA and sulfonamide antibiotics inhibits the antibacterial effects of sulfonamide.

Full Para-aminobenzoic Acid (paba) + Retapamulin answer

Can you take Oleander with Retapamulin?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, macrolide antibiotics may increase the risk of oleander toxicity.

Full Oleander + Retapamulin answer

Can you take Bacillus Coagulans with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.

Full Bacillus Coagulans + Retapamulin answer

Can you take Bacillus Subtilis with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.

Full Bacillus Subtilis + Retapamulin answer

Can you take Bifidobacterium Animalis Subsp. Lactis with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium lactis with antibiotic drugs might decrease the effectiveness of B.

Full Bifidobacterium Animalis Subsp. Lactis + Retapamulin answer

Can you take Bifidobacterium Bifidum with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium.

Full Bifidobacterium Bifidum + Retapamulin answer

Can you take Bifidobacterium Breve with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.

Full Bifidobacterium Breve + Retapamulin answer

Can you take Bifidobacterium Longum with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.

Full Bifidobacterium Longum + Retapamulin answer

Can you take Black Tea with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Black Tea + Retapamulin answer

Can you take Caffeine with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Caffeine + Retapamulin answer

Can you take Calcium with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Calcium seems to reduce the absorption of quinolone antibiotics.

Full Calcium + Retapamulin answer

Can you take Cocoa with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Cocoa + Retapamulin answer

Can you take Coconut Water with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Many quinolone antibiotics, such as ciprofloxacin and levofloxacin, may have reduced absorption when taken with calcium-containing products...

Full Coconut Water + Retapamulin answer

Can you take Coffee with Retapamulin?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.

Full Coffee + Retapamulin answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Retapamulin is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Retapamulin, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Retapamulin sits in 8 interaction categories. Open any one to see what the group means:

Antibiotic Drugs 27 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

27 of the supplement ingredients on this page reach Retapamulin through this category.

Quinolone Antibiotics 24 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

24 of the supplement ingredients on this page reach Retapamulin through this category.

Tetracycline Antibiotics 24 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

24 of the supplement ingredients on this page reach Retapamulin through this category.

Macrolide Antibiotics 11 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

11 of the supplement ingredients on this page reach Retapamulin through this category.

Antitumor Antibiotics 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Retapamulin through this category.

Sulfonamide Antibiotics 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Retapamulin through this category.

Topical Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Retapamulin through this category.

Aminoglycoside Antibiotics 2 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

2 of the supplement ingredients on this page reach Retapamulin through this category.

About Retapamulin

Retapamulin is a prescription medication also sold under the brand names Altabax, Altargo. Because supplements and herbal products can change how medications work — or how strongly — every ingredient on this page has been checked against it in our interaction database.

Generic name: Retapamulin  ·  Brand names: Altabax, Altargo.

See the full Retapamulin drug information

Related: does Retapamulin deplete any nutrients?

Retapamulin has 32 reported nutrient associations in the research literature — see the Retapamulin nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Retapamulin

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Retapamulin.

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Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

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Pharmacist Counseling Corner

Retapamulin & Supplements: Common Questions

What supplements interact with Retapamulin?
In our interaction database, 81 supplement and herbal ingredients have an interaction with Retapamulin on file — 2 rated major, 71 moderate, and 8 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Para-aminobenzoic Acid (paba), Oleander, Bacillus Coagulans.
Which Retapamulin supplement interactions are the most serious?
Focus on the major group: Para-aminobenzoic Acid (paba) and Oleander. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Retapamulin?
That depends entirely on which supplement. The honest answer for Retapamulin is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Altabax have the same supplement interactions as Retapamulin?
Yes — Altabax, Altargo all contain Retapamulin, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Retapamulin deplete any vitamins or nutrients?
It might — Retapamulin has 32 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Retapamulin nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Retapamulin and my other medications?
This page covers Retapamulin against supplements and herbal ingredients. Checking Retapamulin against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Retapamulin drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.