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Dietary supplement

DMAE 320 mg Ingredients & Drug Interactions

by Viva Vitamins

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DMAE 320 mg is a dietary supplement by Viva Vitamins with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Dimethylaminoethanol Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DMAE 320 mg by Viva Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Dimethylaminoethanol Bitartrate” is listed as a grouped ingredient — the label gives one combined amount (350 mg) without saying how much of each component you get.

This product contains one active ingredient: dimethylaminoethanol (DMAE), supplied at 320 mg per capsule. The capsule also holds rice flour and cellulose as inactive fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Deanol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: memory, learning, and brain health support.
  • We looked for evidence on: Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Alzheimer disease, age-related cognitive decline, mental clarity.
  • The closest evidence on file: Deanol is rated "Likely Ineffective" for Alzheimer disease (Natural Medicines).
  • Also on file: Deanol is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

The evidence for DMAE is limited. For Alzheimer disease and tardive dyskinesia (involuntary movement disorder), the data we hold rates it likely ineffective.

For aging skin, ADHD, and athletic performance, there isn't enough reliable evidence to say whether it works or doesn't. If you're considering this supplement for one of those uses, talk it over with your doctor to explore options with stronger evidence.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

DMAE is generally well tolerated by some adults, but side effects do occur. The most common are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting.

Other reported effects include headache, insomnia, confusion, and mood changes. At doses above 1000 mg daily, mood changes (depression and hypomania) have been reported, particularly in people with a psychiatric condition — and at 1500 mg daily, it has been reported to worsen schizophrenia symptoms.

There isn't enough safety data in pregnancy, and the data advises against use while breastfeeding.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take any anticholinergic drugs (allergy medicines, motion sickness treatments, urinary incontinence drugs, certain antidepressants) or cholinergic drugs (Alzheimer's medications like donepezil, or glaucoma drops). Although the interactions are rated Minor, DMAE may shift how these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

DMAE may appeal to people curious about cognitive or skin support, but the evidence it actually works is thin to absent. Side effects are real and range from mild (nausea, drowsiness) to serious (mood changes, worsened psychiatric symptoms) — especially at higher doses.

If you have a psychiatric condition or take medications that affect acetylcholine, check with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE 320 mg, straight from the product label.

Brand Viva Vitamins
Barcode (UPC) 726899842742
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316302
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE 320 mg by Viva Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
726899842742
IngredientAmount% DV
Dimethylaminoethanol130 mg--
Dimethylaminoethanol Bitartrate350 mg--

Other ingredients: Rice Flour, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one capsule daily, or as directed by your health care professional.

Formula

DMAE has shown promise when it comes boosting brain health, particularly in terms of memory and learning. Additionally, it has been shown to have anti-aging effects on the skin.

DMAE 350 mg Dimethyl-amino-Ethanol bitartrate

Storage

Store in a cool, dry place, away from direct light.

Precautions

Keep out of reach of children.

Do not use if safety seal under cap is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

We at viva are proud to use only the best food-based ingredients in our supplements. Our raw materials come from the USA, and we use only organic sources to ensure you're getting the best product possible, from the ground up! We always use the highest quality ingredients Premium formulas

In God We Trust

FDA Statement of Identity

Dietary Supplement

Formulation

Free of: Gluten, sugar, salt, starch, soy, yeast, wheat, lactose, milk, citrus, egg, fish, artificial coloring, flavoring, or preservatives. Non-GMO

Made in the USA Manufactured in an NSF-GMP Certified Facility

Brand IP Statement(s)

Copyright 2020

See for yourself

DMAE 320 mg by Viva Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DMAE 320 mg by Viva Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Dimethylaminoethanol Bitartrate

Interacts with
219 drugs
350 mg per serving

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

Dimethylaminoethanol Bitartrate monograph & interactions

Other (inactive) ingredients: Rice Flour, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE 320 mg by Viva Vitamins Drug Interactions

Want to check YOUR meds against DMAE 320 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE 320 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dimethylaminoethanol Bitartrate2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DMAE 320 mg, from the product label.

Viva Vitamins

Name
Viva Vitamins
City
Los Angeles
State
CA
Web Address
www.VivaVitamins.com
Pharmacist Counseling Corner

DMAE 320 mg by Viva Vitamins: Common Questions

Does DMAE 320 mg by Viva Vitamins interact with any medications?
Yes. Based on its ingredients, DMAE 320 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE 320 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is DMAE, and what is it supposed to do?
DMAE (dimethylaminoethanol) is a compound thought to raise acetylcholine, a brain chemical involved in memory and focus. It's been studied for Alzheimer disease, ADHD, athletic performance, and aging skin — but the data we hold shows it likely doesn't help Alzheimer disease or tardive dyskinesia, and we don't have enough evidence for the others.
What are the most common side effects?
The most frequent side effects are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting. Other people have reported headache, insomnia, confusion, and mood changes. If you have a history of depression, mood swings, or schizophrenia, be especially cautious — higher doses have been tied to worsening symptoms.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way in pregnancy. While breastfeeding, the data advises against it. Talk with your doctor or pharmacist about what's right for your situation before taking it.
Does DMAE interact with many medications?
The interactions are documented with two drug types — anticholinergic drugs and cholinergic drugs — across 219 individual medications. Both interactions are rated Minor, but they're based on theory, not confirmed human studies. Check your exact medications on this page's interaction tool.
Is DMAE well tolerated?
Some adults tolerate it okay, but side effects are common and evidence of safety is limited. The most common ones are mild (nausea, drowsiness, diarrhea), but mood changes and confusion are also reported — and at doses above 1000 mg daily, more serious mood effects have emerged.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE 320 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE 320 mg label
Sources

Sources & How We Checked

DMAE 320 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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