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Dietary supplement

Stimul8 Watermelon Ingredients & Drug Interactions

by FINAFLEX

Stimul8 Watermelon label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stimul8 Watermelon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Stimul8 Watermelon is a dietary supplement by FINAFLEX with 1 active ingredient.Based on those ingredients, 1,256 medications have a known interaction with it, the most serious rated major. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Stimul8 Watermelon by FINAFLEX

Ask about any prescription or over-the-counter medication and we check it for interactions with Stimul8 Watermelon by FINAFLEX — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Stimul8 Watermelon by FINAFLEX

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Stimul8 Thermogenic Ripping Matrix” is a proprietary blend — the label gives one combined amount (2.60 Gram(s)) without saying how much of each component you get.
  • “Xtreme Shredding Matrix” is a proprietary blend — the label doesn't break down how much of each component you get.

Stimul8 Watermelon contains 8 active ingredients. CarnoSyn (beta-alanine) supports athletic and physical performance.

The product also contains caffeine (as 1,3,7-Trimethylxanthine), hordenine HCl, cocoa seed extract, bitter orange (Advantra Z), and three other components: Beta-Phenethylamine HCl, Rauwolfia vomitoria, and IRISINXD. The inactive ingredients are malic acid, watermelon flavoring, citric acid, sucralose, acesulfame potassium, calcium silicate, silica, and FD&C Red #40.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Athletic performance and energy support.
  • We looked for evidence on: Athletic performance, Physical performance, Fatigue, Mental alertness, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 4 related terms.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Caffeine is rated "Likely Effective" for Mental alertness.
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.

Beta-alanine is possibly effective for athletic performance and physical performance, though the evidence is still emerging. For other uses listed — age-related cognitive decline, COPD, cognitive function, and menopausal symptoms — the data we hold shows insufficient evidence to rate it.

Caffeine is likely effective for mental alertness and athletic performance, and effective for neonatal apnea (a newborn breathing condition) and postoperative headache. Cocoa is possibly effective for cardiovascular health.

We don't have effectiveness ratings on file for hordenine, bitter orange for most claims, or the other active ingredients in this formula.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated in healthy adults but commonly causes a harmless tingling sensation (paresthesia) in the skin, usually starting on the scalp within 20 minutes and lasting about an hour. Caffeine in moderate amounts is generally safe for healthy adults, though high doses can cause serious side effects — common ones include anxiety, dependence, diarrhea, headache, insomnia, nausea, and tremors.

Hordenine safety data in humans is very limited; it acts as a stimulant and theoretically may cause increased heart rate (tachycardia) and high blood pressure, though this hasn't been confirmed in people. Bitter orange is not considered safe when taken in medicinal amounts — it can raise blood pressure and heart rate, especially combined with caffeine, and rare serious effects include heart attack, QT prolongation, seizures, and stroke.

Cocoa is generally well tolerated in food amounts but contains caffeine and may cause gastrointestinal upset, headache, and nausea.

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Cocoa, Bitter Orange, Caffeine, Hordenine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,257 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you're on monoamine oxidase inhibitors (used for depression), midazolam or other sedatives, ephedrine or other stimulant drugs, blood pressure medications, diabetes medications, anti-seizure drugs like phenobarbital or carbamazepine, clozapine (an antipsychotic), or any antibiotic from the quinolone family. The stimulant ingredients and caffeine content make this a product to verify carefully with your medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Stimul8 Watermelon is a stimulant-based pre-workout powder marketed for athletic performance. It's not appropriate if you take blood pressure medications, certain antidepressants (especially MAOIs), sedatives like midazolam, or diabetes drugs — and it carries real risks if you take ephedrine or other stimulants.

Even if your medications aren't on the interaction list, check them here before you buy. Talk to your pharmacist or doctor about whether this product fits your health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stimul8 Watermelon, straight from the product label.

Brand FINAFLEX
Barcode (UPC) 689466670219
Net contents 6.5 Oz(s); 184 Gram(s)
Market status On market
Date entered into DSLD Jun 25, 2018
DSLD ID 178379
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stimul8 Watermelon by FINAFLEX, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.6 Gram(s)
Maximum serving Sizes:
4.6 Gram(s)
Servings per container
40
UPC/BARCODE
689466670219
IngredientAmount% DV
CarnoSyn0 NP--
Hordenine HCl0 NP--
Beta-Phenethylamine HCl0 NP--
1,3,7-Trimethylxanthine0 NP--
Rauwolfia vomitoria0 NP--
IRISINXD0 NP--
Advantra Z0 NP--
Stimul8 Thermogenic Ripping Matrix2.6 Gram(s)--
Xtreme Shredding Matrix0 NP--
Theobroma cacao seed extract0 NP--

Other ingredients: Malic Acid, Natural and Artificial Watermelon flavor, Citric Acid, Sucralose, Acesulfame Potassium, Calcium Silicate, Silica, FD&C Red #40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Redefine yourself.

IRISINXD CarnoSyn Carnosine Synthesizer

CarnoSyn trademark and patents owned by Natural Alternatives International Inc., www.carnosyn.com IRISINXD is a registered trademark of FinaFlex, protected by Patent Pending, Serial No. US 14,053,172. Advantra Z is a registered trademark of Nutratech, Inc./Zhishin, LLC licensor of U.S., Canadian and E.U. Patents.

Stimul8 is built with ingredients designed to propel workouts to the next level.

FDA Statement of Identity

Dietary Supplement - 184 grams

Dietary Supplement

Precautions

Warning: Keep out of reach of children.

Do not use if pregnant or nursing.

Consult your physician prior to use if you have or are at risk for prostate disease, heart disease, or any other general medical condition, including but not limited to, heart, liver, kidney, or thyroid disease, psychiatric or epileptic disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate or glaucoma. Do not exceed recommended dosage. Exceeding recommended dosage may cause adverse health effects. All persons are advised to consult with their doctor or other medical authority before use of this or any other dietary supplement.

Discuss possible interactions and contradictions of this dietary supplement with other medicines currently prescribed by your doctor, including but not limited to, MAOI inhibitors, antidepressants, aspirin, nonsteroidal anti-inflammatory drugs or products containing phenylephrine, ephedrine, pseudoephedrine, or other stimulants.

Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product, including but not limited to, rapid heartbeat, dizziness, severe headache or shortness of breath.

Warning: This product contains Caffeine. Do not consume synephrine or caffeine from other sources, including but not limited to, coffee, tea, soda and other dietary supplements or medications containing phenylephrine or caffeine.

Do not use for more than 8 weeks consecutively. Do not use this product in extreme heat conditions. Discontinue use 2 weeks prior to surgery. Do not combine this product with alcohol. Do not use product if your health status is unknown. Do not use this product 5 hours prior to bedtime. Consumer assumes all liability if product is used in a manner inconsistent with label guidelines. Caution: Athletes or other persons who are subject to testing for performance enhancing drugs may test positive when using dietary supplements. All persons are advised to contact their drug testing organization prior to use of this or any other dietary supplement.

Not intended for use by persons under the age of 18 years old.

Do not exceed recommended dosage due to the extremely potent nature of the ingredients contained in Stimul8. Do not use for more than 60 days consecutively. Please see warning label for additional information.

Formula

Warning: This product contains Caffeine.

Powered by IRISINXD a Patent Pending blend of exotic stimulants, Stimul8 engages the body into a state of extreme thermogenesis, slicing through adipose tissue while preserving and increasing lean muscle mass.

Destroy workouts with unparalleled energy delivered by the Xtreme Shredding Matrix and experience ultimate endurance, strength, and power fueled by Beta Alanine.

Suggested/Recommended/Usage/Directions

Contents may settle during transit. Shake container prior to use to redistribute ingredients.

Shredding pre-workout

Suggested use: As a dietary supplement, mix 1 scoop with 8-16 ounces of cold water and consume 15-30 minutes prior to workout. Do not consume more than one scoop of Stimul8 daily. Do not exceed recommended dosage due to the extremely potent nature of the ingredients contained in Stimul8. Do not use for more than 60 days consecutively. Please see warning label for additional information.

Storage

Store in a cool dry place (heat and humidity can cause clumping). Do not discard desiccant pack after opening.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Xtreme effects Naturally & artificially flavored High performance Endurance + ripping matrix Unparalleled energy 40 servings

100% pure adrenaline

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stimul8 Watermelon by FINAFLEX label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stimul8 Watermelon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stimul8 Watermelon by FINAFLEX

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4.6 Gram(s) Dosage formPowder Servings per container40 Amounts shown are per serving.

Stimul8 Thermogenic Ripping Matrix

2.6 Gram(s) per serving
  • › Xtreme Shredding Matrix

Other (inactive) ingredients: Malic Acid, Natural and Artificial Watermelon flavor, Citric Acid, Sucralose, Acesulfame Potassium, Calcium Silicate, Silica, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stimul8 Watermelon by FINAFLEX Drug Interactions

Want to check YOUR meds against Stimul8 Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,256Drugs
18 Major 1,176 Moderate 62 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Stimul8 Watermelon interact with 1,256 drugs. Click any drug to see the details.

0 of the 1 ingredient in Stimul8 Watermelon interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Stimul8 Watermelon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Stimul8 Watermelon, from the product label.

FINAFLEX

See all FINAFLEX products
Name
FinaFlex
Street Address
1190 Tidwell Road, Ste 304
City
Alpharetta
State
GA
ZipCode
30004
Web Address
www.FinaFlex.com
Pharmacist Counseling Corner

Stimul8 Watermelon by FINAFLEX: Common Questions

Does Stimul8 Watermelon by FINAFLEX interact with any medications?
Yes. Based on its ingredients, Stimul8 Watermelon has a known interaction with 1,256 medications, including 18 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stimul8 Watermelon contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me that tingling sensation I've heard about pre-workouts causing?
Probably yes. Beta-alanine, which is in this formula, commonly causes a harmless skin tingling and flushing, usually starting on your scalp within 20 minutes and lasting about an hour. The intensity depends on the dose — at lower amounts, only a small number of people experience it, but at higher doses it's more noticeable. It's not dangerous, just a sensation you'll feel.
Is it safe to use while pregnant or breastfeeding?
No. The safety data for beta-alanine advises against it during pregnancy and while breastfeeding. Hordenine, caffeine, and bitter orange also lack enough safety data in pregnancy or breastfeeding — some carry avoid warnings. Talk with your doctor or pharmacist before using this product if you're pregnant, planning to become pregnant, or breastfeeding.
Does beta-alanine really improve athletic performance?
The evidence shows it's possibly effective for athletic and physical performance, so it may help, but the research is still emerging. It's not proven for other uses listed like cognitive function.
Will this product make my heart race or spike my blood pressure?
It contains multiple stimulants — caffeine, hordenine, and bitter orange — that can raise heart rate and blood pressure, especially when combined. Bitter orange with caffeine specifically has been shown to increase both. If you have heart, blood pressure, or any cardiovascular concerns, talk to your doctor before using it.
What are the common side effects?
The most common are caffeine-related: anxiety, jitteriness, insomnia, nausea, headache, and diarrhea. Beta-alanine causes tingling and flushing. Gastrointestinal discomfort and upset stomach are also possible from the cocoa and other ingredients. If side effects are bothersome, try taking it earlier in the day or with food.
Can I take this every day?
The product facts note that beta-alanine hasn't been studied for long-term high-dose use. Chronic high caffeine intake can lead to dependence. If you want to use it daily, start with the lowest effective dose and talk to your pharmacist about monitoring, especially since this is a multi-ingredient stimulant formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Stimul8 Watermelon is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stimul8 Watermelon label
Sources

Sources & How We Checked

Stimul8 Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 418 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Hordenine 3 references
  1. Barwell CJ, Basma AN, Lafi MA, Leake LD. Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. J Pharm Pharmacol 1989;41(6):421-3. PubMed
  2. Nelson BC, Putzbach K, Sharpless KE, Sander LC. Mass spectrometric determination of the predominant adrenergic protoalkaloids in bitter orange (Citrus aurantium). J Agric Food Chem 2007;55(24):9769-75. PubMed
  3. Liu Y, Santillo MF. Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements. Drug Test Anal. 2016;8(3-4):307-10. PubMed

See these in context on the Hordenine monograph →

Caffeine 236 references
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  2. Harder S, Fuhr U, Staib AH, Wolff T. Ciprofloxacin-caffeine: a drug interaction established using in vivo and in vitro investigations. Am J Med 1989;87:89S-91S. PubMed
  3. Carbo M, Segura J, De la Torre R, et al. Effect of quinolones on caffeine disposition. Clin Pharmacol Ther 1989;45:234-40. PubMed
  4. Healy DP, Polk RE, Kanawati L, et al. Interaction between oral ciprofloxacin and caffeine in normal volunteers. Antimicrob Agents Chemother 1989;33:474-8. PubMed
  5. Mester R, Toren P, Mizrachi I, et al. Caffeine withdrawal increases lithium blood levels. Biol Psychiatry 1995;37:348-50. PubMed
  6. Jefferson JW. Lithium tremor and caffeine intake: two cases of drinking less and shaking more. J Clin Psychiatry 1988;49:72-3.
  7. Joeres R, Klinker H, Heusler H, et al. Influence of mexiletine on caffeine elimination. Pharmacol Ther 1987;33:163-9. PubMed
  8. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  9. Wakabayashi K, Kono S, Shinchi K, et al. Habitual coffee consumption and blood pressure: A study of self-defense officials in Japan. Eur J Epidemiol 1998;14:669-73. PubMed
  10. Hodgson JM, Puddey IB, Burke V, et al. Effects on blood pressure of drinking green and black tea. J Hypertens 1999;17:457-63. PubMed
  11. Rapuri PB, Gallagher JC, Kinyamu HK, Ryschon KL. Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Am J Clin Nutr 2001;74:694-700. PubMed
  12. The National Toxicology Program (NTP). Caffeine. Center for the Evaluation of Risks to Human Reproduction (CERHR). Available at: http://cerhr.niehs.nih.gov/common/caffeine.html.
  13. Klebanoff MA, Levine RJ, DerSimonian R, et al. Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion. N Engl J Med 1999;341:1639-44. PubMed
  14. Eskenazi B. Caffeine—filtering the facts. N Engl J Med 1999;341:1688-9. PubMed
  15. Fernandes O, Sabharwal M, Smiley T, et al. Moderate to heavy caffeine consumption during pregnancy and relationship to spontaneous abortion and abnormal fetal growth: a meta-analysis. Reprod Toxicol 1998;12:435-44. PubMed
  16. Pollock BG, Wylie M, Stack JA, et al. Inhibition of caffeine metabolism by estrogen replacement therapy in postmenopausal women. J Clin Pharmacol 1999;39:936-40. PubMed
  17. Nurminen ML, Niittynen L, Korpela R, Vapaatalo H. Coffee, caffeine and blood pressure: a critical review. Eur J Clin Nutr 1999;53:831-9. PubMed
  18. Dews PB, Curtis GL, Hanford KJ, O'Brien CP. The frequency of caffeine withdrawal in a population-based survey and in a controlled, blinded pilot experiment. J Clin Pharmacol 1999;39:1221-32. PubMed
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  22. Tobias JD. Caffeine in the treatment of apnea associated with respiratory syncytial virus infection in neonates and infants. South Med J 2000;93:297-304. DOI
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  24. Lloyd T, Johnson-Rollings N, Eggli DF, et al. Bone status among postmenopausal women with different habitual caffeine intakes: a longitudinal investigation. J Am Coll Nutr 2000;19:256-61. PubMed
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  33. Horner NK, Lampe JW. Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. J Am Diet Assoc 2000;100:1368-80. PubMed
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  36. Massey LK. Is caffeine a risk factor for bone loss in the elderly? Am J Clin Nutr 2001;74:569-70. PubMed
  37. Dreher HM. The effect of caffeine reduction on sleep quality and well-being in persons with HIV. J Psychosom Res 2003;54:191-8.. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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