Glucose Health Ingredients & Drug Interactions
by Nutrilite
What is this page for?
First and foremost: checking Glucose Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Glucose Health is a dietary supplement by Nutrilite with 5 active ingredients. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 1,220 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gymnema, Garcinia, Nutrilite Parsley concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Glucose Health by Nutrilite
Ask about any prescription or over-the-counter medication and we check it for interactions with Glucose Health by Nutrilite — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Glucose Health by Nutrilite
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Glucose Health contains 5 active ingredients. Chromium is a mineral that supports insulin function and may help with blood sugar control, especially in type 2 diabetes.
Vanadium is another mineral believed to play a role in glucose metabolism. Garcinia is a tropical fruit extract that contains hydroxycitric acid (HCA), which has been studied for its potential effects on fat and carbohydrate metabolism.
Gymnema is an herbal extract traditionally used in Ayurvedic medicine and studied for blood sugar support. Nutrilite Parsley concentrate is a plant extract that contributes additional phytonutrients.
The product also contains inactive ingredients—microcrystalline cellulose, gelatin, water, maltodextrin, magnesium stearate, acacia, and silicon dioxide—which serve as fillers, binders, and capsule material.
Does it work?
Moderate evidence
The effectiveness data for this product is limited. Chromium is rated Likely Effective for chromium deficiency and Possibly Effective for diabetes, but Possibly Ineffective for prediabetes and high blood pressure.
For vanadium, garcinia, gymnema, and parsley, the evidence in our data is marked as insufficient to rate their effectiveness for the conditions this product targets—including athletic performance, fatty liver disease, high cholesterol, obesity, blood sugar control, and urinary tract infections. This means that while these ingredients have been studied, the quality or consistency of the research is not yet strong enough to draw firm conclusions.
How safe is it?
Well-documented data
Chromium is generally well tolerated at typical supplement doses, though long-term or high doses may pose risks. The most common side effects are gastrointestinal irritation, headaches, insomnia, and mood changes.
Rare serious effects include kidney and liver damage and blood disorders. Vanadium at doses above the safe upper limit (1.8 mg daily) may cause stomach upset, diarrhea, nausea, and at high long-term doses, kidney damage.
Garcinia is generally well tolerated short-term, but rare reports link it to liver injury, mania, heart inflammation, and pancreatitis. Gymnema may lower blood sugar and is generally well tolerated short-term; rare cases of liver damage have been reported.
Parsley as a food is safe, but concentrated extracts or large doses may cause hallucinations, blood disorders, low blood pressure, liver and kidney damage, and allergic reactions including anaphylaxis. For pregnancy, chromium is rated Likely Safe or Possibly Safe, but vanadium is Possibly Unsafe in pregnancy.
Garcinia and gymnema are not recommended in pregnancy due to insufficient safety data. Parsley is rated Likely Unsafe in pregnancy and should be avoided in medicinal amounts.
For breastfeeding, vanadium safety is unknown and should be avoided; garcinia and gymnema have insufficient data and should be avoided; parsley data is not on file.
Meds to double-check
Moderate interaction found
Before taking Glucose Health, double-check with your doctor or pharmacist if you take any serotonergic antidepressants (like escitalopram or sertraline)—there's a Moderate risk of serotonin syndrome. Also flag any antidiabetes drugs (including insulin), blood thinners (warfarin, aspirin, or prescription anticoagulants), thyroid medication (levothyroxine), diuretics, or drugs metabolized by your liver's CYP1A2, CYP2C9, or CYP3A4 enzymes.
No interactions are documented for the inactive ingredients we hold monographs for.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Glucose Health is designed for blood sugar support, but it contains multiple ingredients with significant medication interactions—especially with diabetes drugs, blood thinners, thyroid medication, and antidepressants. If you take any prescription medication or have conditions like diabetes, thyroid disease, or bleeding disorders, talk with your doctor or pharmacist before starting this product.
Even if your medications aren't on the list above, the liver-metabolizing interactions are broad enough that it's worth a personalized check.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Glucose Health, straight from the product label.
| Brand | Nutrilite |
|---|---|
| Barcode (UPC) | A8600 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2021 |
| DSLD ID | 246268 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Qualified Health, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Glucose Health by Nutrilite, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Chromium | 100 mcg | 286% |
| Vanadium | 6.7 mcg | -- |
| Garcinia | 300 mg | -- |
| Gymnema | 33.3 mg | -- |
| Nutrilite Parsley concentrate | 33.3 mg | -- |
Other ingredients: Microcrystalline Cellulose, Gelatin, Water, Maltodextrin, Magnesium Stearate, Acacia, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Use Nutrilite Glucose Health in combination with a nutrious low calorie diet and moderate exercise to help support already healthy blood glucose levels and potentially reduce the risk of type 2 diabetes.
1 capsule, 3x a day
Suggested Use: Take one capsule with a large glass of water three times daily, 30-45 minutes before meals.
Formula
Glucose Health is specially formulated with Chromium Picolinate, necessary for the body's utilization of fats, proteins, and carbohydrates - and important for maintaining already normal blood sugar levels. Also combines a blend of garcinia, gymnema, and vanadium for their beneficial effects on the metabolism of the foods we eat.
Crescent M Halal
Formulation
One small study suggests that chromium picolinate may reduce the risk of insulin resistance, and therefore possibly may reduce the risk of type 2 diabetes. FDA concludes, however, that the existence of such a relationship between chromium picolinate and either insulin resistance or type 2 diabetes is highly uncertain.
No artificial flavors, colors or preservatives added.
Support your metabolism with chromium picolinate
Precautions
Children under 12 years of age, pregnant women or nursing mothers, or anyone with a medical condition including diabetes and hypoglycemia should consult with a physician before using this product.
Children under 12 years of age, pregnant women or nursing mothers, or anyone with a medical condition including diabetes and hypoglycemia should consult with a physician before using this product.
Storage
Keep bottle tightly closed. Store in a cool, dry place.
General Statements
Quality you can trust since 1934
Exclusively from Amway
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
Crescent M Halal
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Glucose Health by Nutrilite label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Glucose Health by Nutrilite
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Chromium
Interacts with178 drugs
Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...
Chromium monograph & interactionsVanadium
Interacts with208 drugs
Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...
Vanadium monograph & interactionsGarcinia
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia monograph & interactionsGymnema
Interacts with851 drugs
Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human stu...
Gymnema monograph & interactionsNutrilite Parsley concentrate
Interacts with443 drugs
Parsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a...
Nutrilite Parsley concentrate monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Gelatin, Water, Maltodextrin, Magnesium Stearate, Acacia, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Glucose Health by Nutrilite Drug Interactions
HelloPharmacist Interaction Report
Glucose Health by Nutrilite contains five active ingredients—chromium, vanadium, garcinia, gymnema, and parsley—that together have documented interactions with medications.
The most serious concern is a Moderate-severity interaction between garcinia and serotonergic drugs (like certain antidepressants), which carries a risk of serotonin syndrome, a potentially dangerous condition marked by agitation, confusion, rapid heart rate, and high body temperature.
Read the full breakdown — every affected drug type, severity by severity
Chromium interacts with antidiabetes drugs and insulin, raising the risk of low blood sugar (hypoglycemia). It also affects levothyroxine (thyroid medication) absorption, reducing its levels in your bloodstream by about 17% in one study.
Vanadium and parsley both interact with blood thinners (anticoagulants and antiplatelet drugs), theoretically increasing bleeding risk. Garcinia, vanadium, and parsley all interact with antidiabetes drugs in the same way chromium does—they may increase hypoglycemia risk.
Parsley also interacts with warfarin, possibly reducing its effectiveness, and with diuretics, potentially affecting how they work.
Gymnema interacts with several drug-metabolizing enzymes in your liver (CYP1A2, CYP2C9, and CYP3A4), which means it could raise or lower levels of many medications that depend on those pathways. Parsley and gymnema both theoretically interact with anticoagulants.
Additionally, parsley may increase levels of certain pain relievers and other drugs processed through CYP1A2, and it may increase the duration of barbiturate sedatives like pentobarbital. Altogether, these interactions span 1,221 individual medications.
No interactions are documented in our data for the inactive ingredients in this product. Before taking Glucose Health, run your complete medication list—including any blood thinners, diabetes drugs, thyroid medication, antidepressants, diuretics, or pain relievers—through the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Glucose Health?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Glucose Health interact with 1,220 drugs. Click any drug to see the details.
5 of the 5 ingredients in Glucose Health interact with drugs. Each result below shows which ingredient is responsible. Gymnema Garcinia Nutrilite Parsley concentrate Vanadium Chromium
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Glucose Health — through 1 ingredient. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Glucose Health — through 1 ingredient. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Glucose Health — through 1 ingredient. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
Nutrilite Parsley ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Nutrilite Parsley Concentrate + Abciximab interactionGarciniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia + Abciximab interactionVanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Abciximab interactionAbiraterone
How Abiraterone interacts with Glucose Health — through 2 ingredients. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Abiraterone interactionGymnemaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Glucose Health — through 2 ingredients. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Abiraterone Acetate interactionGymnemaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Glucose Health — through 4 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Abrocitinib interactionGymnemaCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Read the full Gymnema + Abrocitinib interactionNutrilite Parsley ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Nutrilite Parsley Concentrate + Abrocitinib interactionGarciniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Glucose Health — through 5 ingredients. Tap an ingredient for the detail:
GymnemaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Gymnema + Acarbose interactionGarciniaAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia + Acarbose interactionVanadiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vanadium + Acarbose interactionNutrilite Parsley ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Nutrilite Parsley Concentrate + Acarbose interactionChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Glucose Health — through 1 ingredient. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acenocoumarol interactionNutrilite Parsley ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Nutrilite Parsley Concentrate + Acenocoumarol interactionGarciniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Glucose Health — through 5 ingredients. Tap an ingredient for the detail:
VanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acetaminophen, Aspirin interactionGarciniaHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Aspirin interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Aspirin interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Aspirin interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Glucose Health — through 5 ingredients. Tap an ingredient for the detail:
GarciniaAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia + Acetaminophen, Aspirin, Caffeine interactionVanadiumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Vanadium + Acetaminophen, Aspirin, Caffeine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Aspirin, Caffeine interactionGymnemaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Acetaminophen, Aspirin, Caffeine interactionChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
Nutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Butalbital interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Butalbital interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Butalbital, Caffeine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Butalbital, Caffeine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
Nutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Butalbital, Caffeine, Codeine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Butalbital, Caffeine, Codeine interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Butalbital, Codeine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Butalbital, Codeine interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Butalbital, Codeine Phosphate interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Butalbital, Codeine Phosphate interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
Nutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Caffeine, Codeine interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Caffeine, Codeine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Acetaminophen, Caffeine, Codeine, Salicylamide interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Caffeine, Dihydrocodeine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Caffeine, Dihydrocodeine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
Nutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Caffeine, Isometheptene interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Caffeine, Isometheptene interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Acetaminophen, Caffeine, Pyrilamine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Caffeine, Pyrilamine interactionGarciniaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionGarciniaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GymnemaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
Read the full Gymnema + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGarciniaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GarciniaHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GarciniaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Glucose Health — through 3 ingredients. Tap an ingredient for the detail:
GarciniaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionNutrilite Parsley ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Nutrilite Parsley Concentrate + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionGymnemaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Read the full Gymnema + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Glucose Health with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Gymnema
Antidiabetes Drugs
Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Gymnema reduces blood glucose levels in some human and animal research. In human studies, it has been shown to enhance the blood glucose lowering effects of hypoglycemic drugs. However, other research in adults with prediabetes or metabolic syndrome suggests that gymnema does not reduce fasting levels of blood glucose. Until more is known, monitor blood glucose levels closely.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Animal and in vitro research shows that gymnema can inhibit the CYP1A2 enzyme. In one animal study, oral administration of gymnema for 7 days increased the plasma concentrations of phenacetin, a CYP1A2 substrate, by about 1.4-fold and reduced the clearance of phenacetin by about 29%.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Animal research shows that gymnema can induce the CYP2C9 enzyme. In one animal study, gymnema caused a 2.4-fold increase in the clearance of tolbutamide, a CYP2C9 substrate, in rats. In vitro research also shows that gymnema can inhibit CYP2C9.
Phenacetin
Theoretically, taking gymnema with phenacetin might increase the levels of phenacetin.
Animal research shows that gymnema, administered orally for 7 days, decreases the clearance of phenacetin in a dose-dependent manner by about 21% to 29% and increases plasma levels about 1.3- to 1.4-fold when compared to control.
Tolbutamide (Orinase)
Theoretically, taking gymnema with tolbutamide might the decrease levels of tolbutamide.
Animal research shows that gymnema, administered orally for 7 days, increases the clearance of tolbutamide by 2.4-fold when compared to control.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
One in vitro study using rat liver microsomes shows that gymnema can modestly inhibit the CYP3A4 enzyme. However, other in vitro research using human liver microsomes shows that gymnema does not affect CYP3A4 activity. Animal research also shows that gymnema does not alter the function of CYP3A4. In one study in rats, oral administration of gymnema for 7 days did not alter the clearance of amlodipine, a CYP3A4 substrate.
Garcinia
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Nutrilite Parsley concentrate
Anticoagulant/Antiplatelet Drugs
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Animal research suggests that parsley has antiplatelet effects.
Antidiabetes Drugs
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that parsley might decrease blood glucose. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Laboratory research suggests that parsley can inhibit CYP1A2.
Diuretic Drugs
Theoretically, parsley might enhance or interfere with the effects of diuretic drugs.
Animal research suggests that parsley seed extract increases urine elimination. Parsley leaf and root might also interfere with diuretic therapy due their purported aquaretic effects.
Pentobarbital (Nembutal)
Theoretically, parsley might increase the duration of pentobarbital effects.
Animal research suggests that parsley juice prolongs the action of pentobarbital, perhaps by decreasing cytochrome P450 levels. It is not known if this occurs in humans or if this applies to other barbiturates or sedatives.
Sirolimus (Rapamune)
Theoretically, large quantities of parsley might increase sirolimus levels.
In one case report, an adult female with a history of kidney transplant presented with elevated blood sirolimus levels, approximately 4-7 times greater than previous measures, after daily consumption of a juice containing approximately 30 grams of parsley for 7 days. Sirolimus levels returned to normal a week after the parsley juice was discontinued.
Warfarin (Coumadin)
Theoretically, large amounts of parsley leaf and root might decrease the effects of warfarin.
Parlsey contains vitamin K.
Aspirin
Theoretically, aspirin might increase the severity of allergic reactions to parsley.
In one case, severe urticaria and swelling were reported after taking aspirin with parsley in an individual with a known mild parsley allergy.
Vanadium
Anticoagulant/Antiplatelet Drugs
Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.
Antidiabetes Drugs
Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.
Chromium
Antidiabetes Drugs
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.
Insulin
Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,
Levothyroxine (Synthroid, Others)
Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.
Aspirin
Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.
Brand information
Manufacturer and brand details for Glucose Health, from the product label.
Nutrilite
See all Nutrilite products- Name
- Amway Corp.
- City
- Ada
- State
- MI
- ZipCode
- 49355
- Phone Number
- 1-800-253-6500
- Web Address
- Amway.com/Nutrilite
Glucose Health by Nutrilite: Common Questions
Does Glucose Health by Nutrilite interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on diabetes medication?
What's chromium supposed to do in this product?
Is this safe during pregnancy?
What are the most common side effects I might notice?
Does this product actually help with weight or blood sugar?
I take a blood thinner—is this safe?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Glucose Health is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Glucose Health’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chromium
Interacts with 178 drugsChromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...
Read the full Chromium monograph → Herb & supplement monographVanadium
Interacts with 208 drugsVanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and...
Read the full Vanadium monograph → Herb & supplement monographGarcinia
Interacts with 704 drugsGarcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific evidence is weak and mixed, with most studies...
Read the full Garcinia monograph → Herb & supplement monographGymnema
Interacts with 851 drugsGymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human studies are encouraging for blood sugar sup...
Read the full Gymnema monograph → Herb & supplement monographParsley
Interacts with 443 drugsParsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a diuretic and for digestion, but solid hu...
Read the full Parsley monograph →Sources & How We Checked
Glucose Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 145 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chromium 53 references
- Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
- Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
- Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
- Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
- Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
- Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
- McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
- Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
- Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
- Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
- Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
- Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
- Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
- Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
- Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
- Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
- Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
- John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
- Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
- Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
- Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
- Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
- Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
- Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
- Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
- Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
- Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
- Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
- Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
- Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
- Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
- Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
- Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
- Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
- Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
- Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
- Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
- Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Pharmacotherapy 1998;18(4):860-862. DOI
- Proctor, D. M., Fredrick, M. M., Scott, P. K., Paustenbach, D. J., and Finley, B. L. The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study. Regul.Toxicol Pharmacol 1998;28(1 PubMed
- De Marchi S, Cecchin E, De Marchi SU. Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement. Contact Dermatitis 2014;70(2):123-5. PubMed
- Hedberg YS, Gumulka M, Lind ML, Matura M, Lidén C. Severe occupational chromium allergy despite cement legislation. Contact Dermatitis. 2014;70(5):321-3. PubMed
- Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis 2014;70(3):185-7. PubMed
- Liu Y, Cotillard A, Vatier C, et al. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial. PLoS One.
- Jamilian M, Asemi Z. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Nutr Metab. 2015;67(1):42-8. PubMed
- Guimarães MM, Carvalho AC, Silva MS. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry. J Trace Elem Med Bi PubMed
- Paiva AN, Lima JG, Medeiros AC, et al. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. J Trace Elem Med Biol. 2015;32:66-72. PubMed
- Yin RV, Phung OJ. Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutr J. 2015;14:14. PubMed
- Jamilian M, Zadeh Modarres S, Amiri Siavashani M, et al. The influences of chromium supplementation on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome women candidate for in vitro fertilizati
- Alinaghi F, Thyssen JP, Zachariae C, Johansen JD. No immediate effect of regulatory reduction of chromium in leather among adult patients with chromium allergy. Contact Dermatitis 2021;85(5):514-522. PubMed
Vanadium 15 references
- Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
- Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
- Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
- Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
- Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
- Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
- Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
- Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
- Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
- Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
- Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
- Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
- Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
- Leonhardt M, Balkan B, Langhans W. Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutrition 2004;20(10):911-915. PubMed
- Bunchorntavakul, C. and Reddy, K. R. Review article: herbal and dietary supplement hepatotoxicity. Aliment.Pharmacol.Ther 2013;37(1):3-17. PubMed
- Vasques CA, Schneider R, Klein-Júnior LC, et al. Hypolipemic effect of Garcinia Cambogia in obese women. Phytother Res 2014;28(6):887-91.
- Marquez F, Babio N, Bullo M, Salas-Salvado J. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. Crit Rev Food Sci Nutr 2012;52:585-94.
- Allen SF, Godley RW, Evron JM, et al. Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids. Can J Cardiol 2014;30(12):1732 e13-1732 e15. PubMed
- Dara L, Hewett J, Lim JK. Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol. 2008 Dec 7;14(45):6999-7004. PubMed
- Sharma T, Wong L, Tsai N, Wong RD. Hydroxycut(®) (herbal weight loss supplement) induced hepatotoxicity: a case report and review of literature. Hawaii Med J. 2010 Aug;69(8):188-90.
- Rashid NN, Grant J. Hydroxycut hepatotoxicity. Med J Aust. 2010 Feb 1;192(3):173-4. PubMed
- Actis GC, Bugianesi E, Ottobrelli A, Rizzetto M. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis. 2007 Oct;39(10):953-5. PubMed
- Corey R, Werner KT, Singer A, Moss A, Smith M, Noelting J, Rakela J. Acute liver failure associated with Garcinia cambogia use. Ann Hepatol. 2016 Jan-Feb;15(1):123-6. PubMed
- Melendez-Rosado J, Snipelisky D, Matcha G, Stancampiano F. Acute hepatitis induced by pure Garcinia cambogia. J Clin Gastroenterol. 2015 May-Jun;49(5):449-50. PubMed
- García-Cortés M, Robles-Díaz M, Ortega-Alonso A, Medina-Caliz I, Andrade RJ. Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics. Int J Mol Sci. 2016 Apr 9;17(4):537. PubMed
- Dehoney S, Wellein M. Rhabdomyolysis associated with the nutritional supplement Hydroxycut. Am J Health Syst Pharm. 2009;66(2):142-8. PubMed
- Fong TL, Klontz KC, Canas-Coto A, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010;105(7):1561-6. PubMed
- Hendrickson BP, Shaikh N, Occhiogrosso M, Penzner JB. Mania Induced by Garcinia cambogia: A Case Series. Prim Care Companion CNS Disord. 2016;18(2).
- Kaswala D, Shah S, Patel N, Raisoni S, Swaminathan S. Hydroxycut-induced Liver Toxicity. Ann Med Health Sci Res. 2014; 4(1):143-5. PubMed
- Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol. 2009;15(14):1786-7. PubMed
- Lunsford KE, Bodzin AS, Reino DC, Wang HL, Busuttil RW. Dangerous dietary supplements: Garcinia cambogia -associated hepatic failure requiring transplantation. World J Gastroenterol. 2016;22(45):10071-10076.
- Narasimha A, Shetty PH, Nanjundaswamy MH, Viswanath B, Bada Math S. Hydroxycut - Dietary supplements for weight loss: Can they induce mania? Aust N Z J Psychiatry. 2013;47(12):1205-6. PubMed
- Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci. 2009;54(2):406-8. PubMed
- Stohs SJ, Preuss HG, Ohia SE, et al. No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. World J Gastroenterol. 2009;15(32):4087-9. PubMed
- Gavril A, Ribnikar M, Smid L, Luzar B, Stabuc B. Fat burner-induced acute liver injury: case series of four patients. Nutrition. 2018;47:110-114. doi: 10.1016/j.nut.2017.10.002. PubMed
- Bystrak T, Cervera-Hernandez ME, Reddy N, King Z, Bratberg J. Garcinia cambogia, diabetic ketoacidosis, and pancreatitis. R I Med J (2013). 2017 Oct 2;100(10):48-50. NO DOI
- Smith RJ, Bertilone C, Robertson AG. Fulminant liver failure and transplantation after use of dietary supplements. Med J Aust. 2016;204(1):30-2. PubMed
- Nguyen DC, Timmer TK, Davison BC, McGrane IR. Possible Garcinia cambogia-induced mania with psychosis: a case report. J Pharm Pract 2019;32(1):99-102. doi: 10.1177/0897190017734728.
- Yousaf MN, Chaudhary FS, Hodanazari SM, Sittambalam CD. Hepatotoxicity associated with Garcinia cambogia: a case report. World J Hepatol 2019;11(11):735-42.
- Mas Ordeig A, Bordón García N. Hepatotoxicity caused by Garcinia cambogia. Gastroenterol Hepatol 2020;43(3):134-5. DOI
- Cho HK, Han YS, Park JM. Ocular complications of Garcinia cambogia extract diet pills: case report. Eur J Ophthalmol 2019:1120672119872364. PubMed
- Ferreira V, Mathieu A, Soucy G, Giard JM, Erard-Poinsot D. Acute severe liver injury related to long-term Garcinia cambogia intake. ACG Case Rep J. 2020;7(8):e00429. PubMed
- Iqbal U, Anwar H, Siddiqui HU, Mehmood A. Acute Pancreatitis Secondary to Use of Appetite Suppressant: Garcinia cambogia. Cureus. 2019;11(5):e4676. PubMed
- Grigos A, Benmoussa J, Sandhu J, Chaucer B, Clarke M, SH Patel. Acute pancreatitis secondary to Garcinia cambogia; the unknown cost of herbal supplements. JOP. J Pancreas (Online) 2016; 17(3):316-317.
- Sidhu RLS, Labana S, Khehra L. Garcinia cambogia: a link between the "miracle" weight loss pill and acute pancreatitis. Am J Gastroenterol. 2016. 111:S560-S561. DOI
- Vuppalanchi R, Bonkovsky HL, Ahmad J, et al. Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol 2021. PubMed
- Calaquian LL, Yau I. Garcinia cambogia-A Supplement-Related Liver Injury. Cureus 2022;14(2):e22225. PubMed
Gymnema 12 references
- Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. PubMed
- Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300.
- Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. PubMed
- Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.
- Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. PubMed
- Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. PubMed
- Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54.
- Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394.
- Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. PubMed
- Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. PubMed
- Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;
- Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed
Parsley 21 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. DOI
- Eberhard P, Gall HM, Muller I, Moller R. Dramatic augmentation of a food allergy by acetylsalicylic acid. J Allergy Clin Immunol 2000;105:844 PubMed
- Tunali T, Yarat A, Yanardag R, et al. Effect of parsley (Petroselinum crispum) on the skin of STZ induced diabetic rats. Phytother Res 1999;13:138-41.. DOI
- Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
- Kreydiyyeh, S. I. and Usta, J. Diuretic effect and mechanism of action of parsley. J Ethnopharmacol 2002;79(3):353-357. PubMed
- Yanardag, R., Bolkent, S., Tabakoglu-Oguz, A., and Ozsoy-Sacan, O. Effects of Petroselinum crispum extract on pancreatic B cells and blood glucose of streptozotocin-induced diabetic rats. Biol Pharm Bull. 2003;26(8):1206-1210. PubMed
- Bolkent, S., Yanardag, R., Ozsoy-Sacan, O., and Karabulut-Bulan, O. Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study. Phytother.Res 2004;18(12):996-999.
- Ozsoy-Sacan, O., Yanardag, R., Orak, H., Ozgey, Y., Yarat, A., and Tunali, T. Effects of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats. J Ethnopharmacol 3-8-2006;104(1-2):175-181. PubMed
- Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem.Toxicol. 2006;44(9):147 PubMed
- Gadi, D., Bnouham, M., Aziz, M., Ziyyat, A., Legssyer, A., Legrand, C., Lafeve, F. F., and Mekhfi, H. Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats. J Ethnopharmacol 8-17-2009;125(1):170-174. PubMed
- Arslan S, Ucar R, Caliskaner AZ. A Cases of Near-fatal Anaphylaxis: Parsley "Over-use" as an Herbal Remedy. Med Arch. 2014;68(6):426-7.
- Foti C, Cassano N, Mistrello G, Amato S, Romita P, Vena GA. Contact urticaria to raw arugula and parsley. Ann Allergy Asthma Immunol. 2011 May;106(5):447-8. PubMed
- Farzaei MH, Abbasabadi Z, Ardekani MR, Rahimi R, Farzaei F. Parsley: a review of ethnopharmacology, phytochemistry and biological activities. J Tradit Chin Med. 2013;33(6):815-26. PubMed
- Kurtaran M, Koc NS, Aksun MS, Yildirim T, Yilmaz SR, Erdem Y. Petroselinum crispum, a commonly consumed food, affects sirolimus level in a renal transplant recipient: a case report. Ther Adv Drug Saf 2021;12:20420986211009358.
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