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Dietary supplement

Rooibos Ingredients & Drug Interactions

by Herbal Terra

Rooibos label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rooibos against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rooibos is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for caffeine-free beverage, antioxidant support, heart health.Based on those ingredients, 879 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rooibos Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Rooibos by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Rooibos by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Rooibos by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Herbal Terra's Rooibos is a single-ingredient supplement: a dry extract from rooibos leaf. The liquid form also contains alcohol, water, and glycerin as inactive ingredients to keep it in solution.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rooibos product and its label doesn't state a use — see Rooibos's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence that rooibos works for any of the conditions it's commonly marketed for — including age-related cognitive decline, hay fever, anxiety, cancer prevention, cardiovascular disease, or diabetes. That doesn't mean it won't help; it means the research to prove it isn't there yet in our data.

The evidence, ingredient by ingredient Rooibos

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rooibos tea consumed in normal amounts is generally well tolerated. However, this product is a concentrated extract in liquid form, and concentrated extracts haven't been studied enough to call them as safe as the beverage.

One case report described a man who drank 10 cups of rooibos tea daily for over a year and developed liver damage and low blood platelets. While that's an extreme dose, it signals the need for caution with concentrated forms and regular long-term use.

Talk with your provider or pharmacist before making this a daily habit.

Side effects, ingredient by ingredient Rooibos

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rooibos.
  • The most serious interaction on file is rated Moderate.
  • For scale: 880 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you're on any of the following: medications broken down by CYP3A4, CYP2C19, CYP1A2, CYP2D6, or CYP2C9 enzymes (a very large category spanning hundreds of drugs); ACE inhibitors (blood pressure and heart medications); or atorvastatin (a cholesterol drug). All of these carry Moderate risk of increased effects.

Use our medication checker for your specific prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're thinking of rooibos as a casual tea-like supplement, the safety profile is reassuring. But as a concentrated liquid extract used regularly, and especially if you take any prescription medications, you need to check your exact drugs first — the enzyme interactions here are real and can affect how your body clears medications.

Run your prescriptions through our checker, and have a conversation with your pharmacist or doctor before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rooibos, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7238361191348
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 325344
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rooibos by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7238361191348
IngredientAmount% DV
Rooibos Leaf Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Aspalathus linearis

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rooibos by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rooibos label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rooibos by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Rooibos Leaf Extract, Dry

Interacts with
879 drugs
983 mg per serving

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early...

Rooibos Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rooibos by Herbal Terra Drug Interactions

Want to check YOUR meds against Rooibos?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
879Drugs
879 Moderate

Ingredients driving the most interactions

Rooibos Leaf Extract, Dry 879

Individual Drug Interactions

The ingredients in Rooibos interact with 879 drugs. Click any drug to see the details.

1 of the 1 ingredient in Rooibos interact with drugs. Each result below shows which ingredient is responsible. Rooibos Leaf Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Rooibos with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rooibos Leaf Extract, Dry7 drug types · 879 drugs

Ace Inhibitors (Aceis)

Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.

Likelihood Possible Evidence D
Rooibos Leaf Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rooibos, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Rooibos by Herbal Terra: Common Questions

Does Rooibos by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Rooibos has a known interaction with 879 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rooibos contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to drink rooibos tea every day?
Normal beverage amounts are generally well tolerated. But this is a concentrated extract, and we don't have safety data for daily long-term use of concentrated forms. Check with your provider before making it a daily routine, especially if you have liver concerns or take medications.
Will rooibos help with anxiety or brain health?
We don't have reliable evidence that rooibos works for anxiety, memory problems, or other cognitive issues. The research to prove it isn't there yet in our data.
What's in this liquid formula besides the rooibos?
The extract itself comes in alcohol, water, and glycerin — all inactive ingredients that keep it liquid. No fillers or binders beyond those.
Can I take this while pregnant or breastfeeding?
We don't have safety information on file for rooibos during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice — they can weigh the risks and benefits for your situation.
Why does this interact with so many medications?
Rooibos inhibits five major liver enzyme systems that your body uses to break down drugs. When those enzymes are slowed, many medications — ones that rely on those pathways — can linger longer and reach higher levels in your blood. That's why even a single-ingredient supplement can interact with hundreds of different drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rooibos is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rooibos label
Go deeper

The Full Monographs Behind Rooibos’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rooibos

Interacts with 879 drugs

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early studies suggest possible benefits for he...

Read the full Rooibos monograph →
Sources

Sources & How We Checked

Rooibos's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rooibos 4 references
  1. Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
  2. Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
  3. Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
  4. Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed

See these in context on the Rooibos monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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