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Dietary supplement

Green Rooibos Extract Ingredients & Drug Interactions

by Big Tree

Green Rooibos Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Green Rooibos Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Green Rooibos Extract is a dietary supplement by Big Tree with 1 active ingredient. Its ingredients are commonly taken for caffeine-free beverage, antioxidant support, heart health.Based on those ingredients, 879 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Aspalathus linearis extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Green Rooibos Extract by Big Tree

Ask about any prescription or over-the-counter medication and we check it for interactions with Green Rooibos Extract by Big Tree — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Green Rooibos Extract by Big Tree

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Big Tree Green Rooibos Extract contains a single active ingredient: an extract of Aspalathus linearis, the plant commonly known as rooibos. The capsules also contain inactive ingredients—vegetable cellulose capsule material, microcrystalline cellulose (a binder), silicon dioxide, and magnesium stearate—which serve as fillers and capsule structure but don't contribute to the supplement's effects.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rooibos product and its label doesn't state a use — see Rooibos's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that rooibos extract works for any of the conditions it's marketed for—age-related cognitive decline, hay fever, anxiety, cancer, heart disease, or diabetes. All of these are rated as having insufficient reliable evidence.

That doesn't mean rooibos is ineffective; it means the research to date isn't robust enough to draw firm conclusions. If you're considering this for a specific health goal, talk it over with your doctor or pharmacist to see what the current science supports.

The evidence, ingredient by ingredient Rooibos

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rooibos tea itself is generally well tolerated when consumed as a regular beverage in typical amounts. However, this product is a concentrated extract, which hasn't been well studied.

Safety data notes that extracts warrant caution and should be discussed with your provider before regular use. On the adverse-effects side, long-term, high-dose rooibos consumption has been linked to liver damage in rare cases—one documented case involved a man drinking 10 cups of rooibos tea daily for over a year, who developed hepatic dysfunction and low platelet counts.

Pregnancy and lactation safety data for rooibos is not on file in our data.

Side effects, ingredient by ingredient Rooibos

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rooibos.
  • The most serious interaction on file is rated Moderate.
  • For scale: 880 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take atorvastatin (Lipitor) or any ACE inhibitor blood pressure medication, you'll want to check before using this product. Additionally, check any medications processed through the liver enzymes CYP3A4, CYP2C19, CYP2D6, CYP1A2, or CYP2C9—a long list that includes many common drugs.

Use the medication search tool below with your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Big Tree Green Rooibos Extract is a single-ingredient product whose effectiveness for common health claims hasn't been reliably proven. More importantly, it interacts with a large number of medications by slowing how your liver clears them—most critically atorvastatin and blood pressure drugs.

Before starting this product, check all your current prescriptions with the tool on this page, and talk with your own doctor or pharmacist about whether it's appropriate for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Green Rooibos Extract, straight from the product label.

Brand Big Tree
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2013
DSLD ID 17042
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Green Rooibos Extract by Big Tree, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Aspalathus linearis extract350 mg--

Other ingredients: Vegetable Cellulose Capsule, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: 1 capsule twice daily or as directed by a healthcare practitioner.

Precautions

Do not use during pregnancy or while breastfeeding.

Keep out of reach of children.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

General Statements

Please recycle.

See underside for batch number and expiry date.

Formulation

*Organically grown without the use of synthetic pesticides, herbicides or chemical fertilizers.

Free of corn, yeast, wheat, soy, salt, sugar and dairy products and formulated without preservatives, artificial colours or flavours.

Suitable for vegans.

Pesticide residue free.

Formula

Aspalathus linearis

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Green Rooibos Extract by Big Tree label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Green Rooibos Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Green Rooibos Extract by Big Tree

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Aspalathus linearis extract

Interacts with
879 drugs
350 mg per serving

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early...

Aspalathus linearis extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Capsule, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Green Rooibos Extract by Big Tree Drug Interactions

Want to check YOUR meds against Green Rooibos Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
879Drugs
879 Moderate

Ingredients driving the most interactions

Aspalathus linearis extract 879

Individual Drug Interactions

The ingredients in Green Rooibos Extract interact with 879 drugs. Click any drug to see the details.

1 of the 1 ingredient in Green Rooibos Extract interact with drugs. Each result below shows which ingredient is responsible. Aspalathus linearis extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Green Rooibos Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Aspalathus linearis extract7 drug types · 879 drugs

Ace Inhibitors (Aceis)

Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.

Likelihood Possible Evidence D
Aspalathus linearis extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Green Rooibos Extract, from the product label.

Big Tree

See all Big Tree products
Name
Big Tree Nutraceutical
Street Address
PO Box 889
City
Wilderness
ZipCode
6560
Pharmacist Counseling Corner

Green Rooibos Extract by Big Tree: Common Questions

Does Green Rooibos Extract by Big Tree interact with any medications?
Yes. Based on its ingredients, Green Rooibos Extract has a known interaction with 879 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Green Rooibos Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a statin or blood pressure medication?
Not without checking with your doctor or pharmacist first. This product can significantly increase levels of atorvastatin (Lipitor) and may boost the effects of ACE inhibitor blood pressure drugs in ways that could be unsafe. Use the search tool on this page with your specific medications, then talk it over with your own healthcare provider.
Is rooibos extract safe to take long-term?
Rooibos tea consumed as a normal beverage is generally well tolerated, but concentrated extracts like this one haven't been well studied for long-term use. Safety data suggests caution with extracts and recommends checking with your provider before regular use. Very high intakes over months have been linked to rare liver damage.
Does this help with anxiety, heart disease, or diabetes?
We don't have reliable evidence that rooibos extract works for any of those conditions. The research to date isn't strong enough to draw solid conclusions, so we can't say whether it helps. Your doctor is the best source for what treatment options are actually proven for your situation.
What is rooibos, and why is it in the extract?
Rooibos (Aspalathus linearis) is a plant native to South Africa often brewed as a caffeine-free tea. This product concentrates that plant material into capsule form, but the concentrated extract hasn't been studied as thoroughly as the tea itself.
Are there any fillers in this product?
Yes. Besides the rooibos extract, the capsules contain vegetable cellulose (the capsule material itself), microcrystalline cellulose, silicon dioxide, and magnesium stearate—all inactive binders and flow agents.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Green Rooibos Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Green Rooibos Extract label
Go deeper

The Full Monographs Behind Green Rooibos Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rooibos

Interacts with 879 drugs

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early studies suggest possible benefits for he...

Read the full Rooibos monograph →
Sources

Sources & How We Checked

Green Rooibos Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rooibos 4 references
  1. Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
  2. Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
  3. Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
  4. Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed

See these in context on the Rooibos monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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