Green Propolis Extract Ingredients & Drug Interactions
by CATALO
What is this page for?
First and foremost: checking Green Propolis Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Green Propolis Extract is a dietary supplement by CATALO with 6 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 2,184 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, FLAV-G, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Green Propolis Extract by CATALO
Ask about any prescription or over-the-counter medication and we check it for interactions with Green Propolis Extract by CATALO — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Green Propolis Extract by CATALO
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Green Propolis Extract by CATALO contains 9 ingredients, of which sodium, quercetin, and chrysin are the active components. Sodium is an electrolyte essential in small amounts but can raise blood pressure and affect certain medications at higher intakes.
Quercetin is a plant flavonoid studied for antioxidant and anti-inflammatory properties. Chrysin is another flavonoid from propolis.
The product also contains several other ingredients we could not fully assess for interactions: pinocembrin, flavonoids, tecto-chrysin, galangin, artepillin-C, and kaempferol. The capsule also holds inactive ingredients (cellulose, polysaccharides, magnesium stearate, and silicon dioxide) that serve as binders and fillers.
Does it work?
Strong evidence
The evidence for this product's benefits is limited in the data we hold. Sodium is rated likely effective for cystic fibrosis and possibly effective for preventing amphotericin B kidney damage—but that's standard medical use, not the propolis extract itself.
For quercetin and chrysin, the effectiveness ratings we have are either insufficient evidence or possibly ineffective (quercetin for athletic performance). The propolis components as a whole lack established evidence for the conditions people typically use them for.
How safe is it?
Well-documented data
Sodium is well tolerated at normal dietary amounts but poses real risks at high intakes: it's linked to high blood pressure, kidney strain, and worsened cardiovascular disease in some people. The safety data cautions against sodium supplements or very high intake without medical guidance.
Quercetin may cause headache or tingling in the extremities, and long-term safety at supplement doses isn't well studied. Chrysin appears well tolerated in short-term use, but long-term safety is unclear.
For pregnancy and breastfeeding: sodium is rated likely safe during pregnancy but possibly unsafe during lactation. Quercetin and chrysin both lack enough safety information—avoid supplemental doses of either during pregnancy or while breastfeeding.
Talk with your doctor or pharmacist about your individual situation.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take blood pressure medications (sodium can reduce their effectiveness), lithium (sodium can raise toxicity risk), warfarin or other blood thinners (chrysin and quercetin may increase bleeding risk), birth control pills (chrysin may reduce efficacy), pravastatin or other statin-like cholesterol drugs (quercetin can raise their levels), or any drug metabolized by your liver's cytochrome P450 enzymes. High sodium in this supplement is a particular concern if you have heart disease, high blood pressure, or kidney disease.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood pressure medications, lithium, warfarin, or contraceptives, this product warrants a careful check with your own doctor or pharmacist before starting, because the sodium and flavonoids here carry documented interactions. Even if you don't take those specific drugs, the sodium content means you'll want to review your total sodium intake and any medications it could affect.
The effectiveness evidence for propolis extract itself is not established in our data.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Green Propolis Extract, straight from the product label.
| Brand | CATALO |
|---|---|
| Barcode (UPC) | 810399022077 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 303068 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Children 4 or More Years of Age, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Green Propolis Extract by CATALO, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 0.9 Gram(s) | -- |
| Sugar | 0 Gram(s) | -- |
| Sodium | 5 mg | -- |
| Energy | 2 Kcal(s) | -- |
| Total Fat | 0 Gram(s) | -- |
| Saturated Fat | 0 Gram(s) | -- |
| Trans Fat | 0 Gram(s) | -- |
| Dietary Fiber | 0.6 Gram(s) | -- |
| Protein | 0.03 Gram(s) | -- |
| Quercetin | 0 NP | -- |
| Pinocembrin | 0 NP | -- |
| Flavonoids | 10 mg | -- |
| Chrysin | 0 NP | -- |
| Tecto-Chrysin | 0 NP | -- |
| Galangin | 0 NP | -- |
| FLAV-G | 200 mg | -- |
| Artepillin-C | 0 NP | -- |
| Kaempferol | 0 NP | -- |
Other ingredients: Cellulose, Polysaccharides, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Active propolis standard flavonoids
Extra Green Propolis Extract
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Serving directions For adults, take 2 capsules 1-2 times daily. For age 12-18, take 2 capsules daily. For age 6-11, take 1 capsules daily. Take after meal
Storage
Storage Keep in a dry and cool place. Avoid direct sunlight
General Statements
Net weight 30.9 (515mg x 60 capsules)
Scan and discover more about this product!
Brand IP Statement(s)
Green Extraction is a trademark of NaturalNectar LLC. NaturaNectar Protect & activate wellness naturally FLAV-G is manufactured by PhenolicFactory LLC and used under license from NaturaNectar LLC. NaturaNectar. All rights reserved.
Formulation
Made in USA
Seals/Symbols
cGMP Current Good Manufacturing Practices
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Green Propolis Extract by CATALO label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Green Propolis Extract by CATALO
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsEnergy
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProtein
FLAV-G
Interacts with921 drugs
Propolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies. Early research sugges...
FLAV-G monograph & interactionsOther (inactive) ingredients: Cellulose, Polysaccharides, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Green Propolis Extract by CATALO Drug Interactions
HelloPharmacist Interaction Report
Green Propolis Extract by CATALO contains sodium, quercetin, and chrysin—three ingredients with documented interactions.
The most serious concern is sodium's moderate-severity effect on blood pressure control: high sodium intake can reduce the effectiveness of antihypertensive drugs, and in some patients may require higher medication doses to maintain blood pressure control.
Read the full breakdown — every affected drug type, severity by severity
Sodium also interacts moderately with corticosteroids (increasing the risk of high blood sodium levels), lithium (altering lithium levels and raising toxicity risk), didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs. Quercetin carries moderate interactions with losartan, OATP substrates (a broad enzyme system affecting drug transport), pravastatin, warfarin, quinolone antibiotics, cyclosporine, sulfasalazine, and mitoxantrone.
Chrysin has moderate interactions with estrogens, contraceptive drugs, blood thinners and antiplatelet drugs, diclofenac, aromatase inhibitors, and mephenytoin—plus minor interactions with certain cytochrome P450 1A2 substrates and glucuronidated drugs.
We could not check several other ingredients in this product: pinocembrin, flavonoids (the broader category), tecto-chrysin, galangin, the blend component FLAV-G, artepillin-C, and kaempferol. Altogether, these interactions span 1,289 individual medications.
Before you start this supplement, run your exact medications through the search tool on this page or talk with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Green Propolis Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Green Propolis Extract interact with 2,184 drugs. Click any drug to see the details.
3 of the 6 ingredients in Green Propolis Extract interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber FLAV-G Sodium
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Green Propolis Extract — through 2 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Ado-trastuzumab Emtansine interactionFlav-gCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
ChrysinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chrysin might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Chrysin + Abciximab interactionFlav-gAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, propolis might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
Read the full Flav-g + Abciximab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Abemaciclib interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Abemaciclib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Abiraterone interactionFlav-gCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Abiraterone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Abiraterone Acetate interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Abiraterone Acetate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Quercetin + Abrocitinib interactionChrysinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chrysin might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Chrysin + Abrocitinib interactionFlav-gAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Moderate
Interaction Summary
Theoretically, propolis might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
Read the full Flav-g + Abrocitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acalabrutinib interactionFlav-gCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Acalabrutinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Green Propolis Extract — through 2 ingredients. Tap an ingredient for the detail:
QuercetinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of quercetin and antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Quercetin + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionQuercetinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking quercetin with antihypertensive drugs might increase the risk of hypotension.
Read the full Quercetin + Acebutolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
ChrysinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chrysin might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Chrysin + Acenocoumarol interactionFlav-gAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, propolis might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
Read the full Flav-g + Acenocoumarol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
Read the full Flav-g + Acetaminophen interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
ChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Aspirin interactionFlav-gCytochrome P450 2e1 (cyp2e1) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Aspirin interactionQuercetinOrganic Anion Transporter 3 (oat3) Substrates, Organic Anion Transporter 1 (oat1) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the effects and adverse effects of OAT3 substrates.
Read the full Quercetin + Acetaminophen, Aspirin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
Read the full Flav-g + Acetaminophen, Aspirin, Caffeine interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs +1 Moderate
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Aspirin, Caffeine interactionQuercetinOrganic Anion Transporter 1 (oat1) Substrates, Organic Anion Transporter 3 (oat3) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use might increase the effects and adverse effects of OAT1 substrates.
Read the full Quercetin + Acetaminophen, Aspirin, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
Read the full Flav-g + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Green Propolis Extract — through 3 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Butalbital interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Butalbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
Read the full Flav-g + Acetaminophen, Butalbital, Caffeine interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Butalbital, Caffeine interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Butalbital, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Butalbital, Caffeine, Codeine interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Butalbital, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine, Codeine interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Acetaminophen, Butalbital, Codeine interactionFlav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Butalbital, Codeine interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Butalbital, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
Read the full Flav-g + Acetaminophen, Butalbital, Codeine Phosphate interactionQuercetinCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Acetaminophen, Butalbital, Codeine Phosphate interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Butalbital, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionQuercetinCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Caffeine, Codeine interactionFlav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Caffeine, Codeine interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
Read the full Flav-g + Acetaminophen, Caffeine, Codeine, Salicylamide interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Caffeine, Codeine, Salicylamide interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Caffeine, Codeine, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Caffeine, Dihydrocodeine interactionQuercetinCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Acetaminophen, Caffeine, Dihydrocodeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Dihydrocodeine interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Caffeine, Isometheptene interactionFlav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Caffeine, Isometheptene interactionChrysinCytochrome P450 1a2 (cyp1a2) Substrates, Glucuronidated Drugs Minor
Interaction Summary
Theoretically, chrysin might increase levels of drugs metabolized by CYP1A2.
Read the full Chrysin + Acetaminophen, Caffeine, Isometheptene interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Acetaminophen, Caffeine, Pyrilamine interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Caffeine, Pyrilamine interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Caffeine, Pyrilamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionFlav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
Read the full Flav-g + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
Flav-gCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Read the full Flav-g + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionQuercetinCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might alter the effects and adverse effects of CYP3A4 substrates.
Read the full Quercetin + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Green Propolis Extract — through 4 ingredients. Tap an ingredient for the detail:
QuercetinCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionFlav-gCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
Read the full Flav-g + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionChrysinGlucuronidated Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, chrysin might increase the clearance of drugs that are UGT1A1 substrates, thereby reducing their effectiveness.
Read the full Chrysin + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Green Propolis Extract with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
FLAV-G
Anticoagulant/Antiplatelet Drugs
Theoretically, propolis might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that propolis water extract and the propolis constituent, caffeic acid phenethyl ester, can inhibit platelet aggregation. Additionally, evidence from an animal model shows that taking propolis in addition to warfarin decreases INR, suggesting that propolis can decrease the effectiveness of warfarin.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
In vitro research shows that propolis extract can inhibit CYP1A2. However, animal research shows that propolis extract does not significantly affect CYP1A2 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP1A2 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2C19.
In vitro research shows that propolis extract can inhibit CYP2C19. However, animal research shows that propolis extract does not significantly affect CYP2C19 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP2C19 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2C9.
In vitro research shows that propolis extract can inhibit CYP2C9. However, animal research shows that propolis extract does not significantly affect CYP2C9 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP2C9 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
In vitro research shows that propolis extract can inhibit CYP2D6. However, animal research shows that propolis extract does not significantly affect CYP2D6 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP2D6 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
In vitro research shows that propolis can inhibit CYP2E1. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Some in vitro research shows that propolis extract can inhibit CYP3A4; however, other in vitro research shows that propolis has no effect on CYP3A4 activity. Furthermore, animal research shows that propolis extract does not significantly affect CYP3A4 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that might in inhibit CYP3A4 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.
Warfarin (Coumadin)
Theoretically, propolis might decrease the effectiveness of warfarin.
Animal research shows that taking propolis in addition to warfarin decreases the international normalized ratio (INR). This effect has not been reported in humans.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Green Propolis Extract, from the product label.
CATALO
See all CATALO products- Name
- CATALO Natural Health Foods
- Street Address
- 5/F, Suite C-D, 15 Cheung Shun St.
- City
- Hong Kong
- Phone Number
- (852) 3556 8686
- Web Address
- CATALO.com
Green Propolis Extract by CATALO: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Green Propolis Extract is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Green Propolis Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographBlack Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographPropolis
Interacts with 921 drugsPropolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies. Early research suggests it may help with cold sores, mouth so...
Read the full Propolis monograph → Herb & supplement monographQuercetin
Interacts with 1,169 drugsQuercetin is a plant flavonoid with antioxidant and anti-inflammatory properties found in many common foods and sold as a supplement. While early research is interesting for allergies, blood...
Read the full Quercetin monograph → Herb & supplement monographChrysin
Interacts with 358 drugsChrysin is a plant flavonoid sold mainly as a bodybuilding supplement claimed to raise testosterone or block estrogen, but human studies have not shown these benefits, largely because the bo...
Read the full Chrysin monograph →Sources & How We Checked
Green Propolis Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 126 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
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