Glucagon

24 interactions 3 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amitriptyline Trospium / Xanomeline Ipratropium Oral Inhalation Atropine Ophthalmic Cyclopentolate Ophthalmic Diphenhydramine Injection
10 Major 14 Moderate
All (24) Major (10) Moderate (14)

Moderate

Glucagon Atenolol Tenormin Explained A transient increase in pulse and blood pressure Details Glucagon Acebutolol Sectral® A transient increase in pulse and blood pressure Details Glucagon Betaxolol Betoptic S A transient increase in pulse and blood pressure Details Glucagon Betaxolol Ophthalmic Betoptic® A transient increase in pulse and blood pressure Details Glucagon Bisoprolol Zebeta® A transient increase in pulse and blood pressure Details Glucagon Esmolol Brevibloc A transient increase in pulse and blood pressure Details Glucagon Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Decreased blood glucose-lowering effects; interference with glucagon action Details Glucagon Insulin Detemir (Rdna Origin) Injection Levemir Decreased blood glucose-lowering effects; interference with glucagon action Details Glucagon Insulin Glulisine (Rdna Origin) Injection Apidra Decreased blood glucose-lowering effects; interference with glucagon action Details Glucagon Labetalol Normodyne® A transient increase in pulse and blood pressure Details Glucagon Levobunolol Ophthalmic AKBeta® A transient increase in pulse and blood pressure Details Glucagon Nadolol Corgard A transient increase in pulse and blood pressure Details Glucagon Nebivolol Bystolic A transient increase in pulse and blood pressure Details Glucagon Penbutolol Levatol® A transient increase in pulse and blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.