Tiratricol - Ofev (Nintedanib Esylate) Interaction

Interaction Details

Nintedanib Esylate is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs

Theoretically, tiratricol might increase the hypoprothrombinemic effects of oral anticoagulants.
Tiratricol is related to thyroid hormones such as levothyroxine. The hypoprothrombinemic effects of oral anticoagulants, including warfarin (Coumadin), are increased by levothyroxine due to increased catabolism of vitamin K-dependent clotting factors. It is not known if tiratricol has a similar effect.

Interaction Rating

Likelihood of Occurrence

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

• McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.

Nintedanib Esylate Overview

• Nintedanib is used to treat idiopathic pulmonary fibrosis (IPF; scarring of the lungs with an unknown cause). It is also used to treat certain types of chronic fibrosing interstitial lung diseases (ILD; an ongoing disease in which there is increased scarring of the lungs). Nintedanib is also used to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD; also known as scleroderma-associated ILD: a disease in which there is scarring of the lungs that is often fatal). Nintedanib is in a class of medications called kinase inhibitors. It works by blocking the action of enzymes involved in causing fibrosis.

Tiratricol - More Interactions

Tiratricol interacts with 222 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.