Drug Interactions Directory

2,618 drugs with documented interactions.

2,618Drugs
67,117Interactions
53,805Serious (major+)
PharmacistReviewed
1Look up a drugSearch by generic or brand name, or browse A-Z.
2Scan the severityInteractions are grouped and color-coded by how much they matter.
3Read the write-upPlain-English and clinical explanations, with cited evidence.
Popular: Buprenorphine 633 Hydroxychloroquine 631 Ketoconazole Topical 546 Cyclosporine Injection 545 Cyclosporine Ophthalmic 545 Sertraline 532 Amitriptyline 525 Fentanyl Transdermal Patch 493

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

C
Cefprozil 27 Ceftaroline Fosamil 1 Ceftaroline Injection 3 Ceftazidime 7 Ceftazidime Injection 18 Cefteram Pivoxil 1 Ceftibuten 9 Ceftobiprole Medocaril 4 Ceftriaxone 4 Ceftriaxone Injection 12 Cefuroxime 38 Cefuroxime Axetil 8 Cefuroxime Injection 19 Celecoxib 104 Celiprolol 58 Cemiplimab-Rwlc Injection 15 Cenobamate 54 Cephalexin 16 Cephaloridine 1 Cephradine 1 Ceritinib 174 Cerivastatin 11 Certolizumab Injection 26 Certolizumab Pegol 7 Certoparin 49 Cetirizine 21 Cetirizine Injection 180 Cetirizine Ophthalmic 180 Cetuximab Injection 15 Chamomile 5 Chan Su 1 Chaparral 16 Chenodiol 6 Chloral Hydrate 39 Chlorambucil 21 Chloramphenicol 21 Chloramphenicol Injection 30 Chlordiazepoxide 24 Chloroprocaine 25 Chloroquine 332 Chlorothiazide 71 Chlorotrianisene 4 Chlorpheniramine 23 Chlorphenoxamine 1 Chlorpromazine 89 Chlorpropamide 59 Chlorprothixene 6 Chlortetracycline 18 Chlorthalidone 73 Chlorzoxazone 35 Cholecalciferol 6 Cholera Vaccine 169 Cholera Vaccine, Live 95 Cholestyramine 40 Cholestyramine Resin 70 Cholic Acid 5 Choline Magnesium Trisalicylate 18 Choline Salicylate 87 Chondroitin 5 Chromium 1 Chromogranin A Measurement 1 Ciclesonide 7 Ciclesonide Nasal Spray 36 Ciclesonide Oral Inhalation 36 Cidofovir 7 Cidofovir Injection 13 Cilazapril 11 Cilnidipine 8 Cilostazol 78 Ciltacabtagene Autoleucel Injection 15 Cimetidine 83 Cimetropium 1 Cinacalcet 8 Cinchona 5 Cinnarizine 1 Cinoxacin 2 Ciprofibrate 14 Ciprofloxacin 162 Cisapride 79 Cisatracurium 22 Cisplatin 10 Cisplatin Injection 39 Citalopram 132 Cladribine 16 Cladribine Injection 16 Clarithromycin 197 Clemastine 11 Clemizole 1 Clevidipine 9 Clidinium 11 Clindamycin 84 Clindamycin Injection 78 Clindamycin Topical 78 Clindamycin Vaginal 78 Clobazam 48 Clobetasol 32 Clobetasol Topical 29 Clobetasone 5 Clocortolone 5 Clofarabine 4 Clofarabine Injection 20 Clofazimine 85 Clofibrate 15 Clomipramine 197 Clonazepam 31 Clonidine 52 Clonidine Transdermal Patch 250 Clonixin 87 Clopamide 48 Clopidogrel 359 Clorazepate 26 Clorazepate Dipotassium 2 Clorgyline 3 Clostebol 1 Clothiapine 59 Clotrimazole 38 Clotrimazole Lozenge 35 Clotrimazole Topical 35 Clotrimazole Vaginal 35 Clove Oil 16