Medication interaction hub

What Supplements Interact with Glucagon?

Glucagon brand names: Glucagon, Baqsimi. Every interaction below applies to the brands too.

256 Interactions 2 Major 215 Moderate 39 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Glucagon? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Glucagon against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

If you keep glucagon (Baqsimi) on hand to rescue a severe low blood sugar, read this list with genuine care. Of the 256 supplements and herbs on file, 239 affect blood sugar control, most by lowering glucose further, which can set up the very crash glucagon exists to reverse. Two carry a major rating: Siberian cocklebur has caused severe hypoglycemia in people who consumed it, and activated charcoal binds many medicines and cuts how much reaches the bloodstream.

The other 215 moderate and 39 minor entries mostly follow that same blood sugar theme, though a few, niacin among them, push glucose up instead, so readings can drift in either direction. A smaller cluster of 17 can slow or block the absorption of medicines swallowed by mouth; keep those spaced well apart from oral doses. Make sure neither major is in your cabinet first, then work through the rest against what you actually take.

— , Clinical Pharmacist · July 18, 2026

Major 2 Moderate 215 Minor 39 No known interaction 1,196

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Glucagon: Top Interactions at a Glance

The most significant Glucagon supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 256 interacting ingredients — plus 1,196 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Glucagon + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Siberian Cocklebur + Glucagoni

Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans.

Read the full interaction Major Likelihood Probable Activated Charcoal + Glucagoni

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction
The complete list

Every Supplement Checked Against Glucagon

All 1,452 ingredients in our database, ranked by severity — 256 with a Glucagon interaction on file and 1,196 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Glucagon?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Oats with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.

Full Oats + Glucagon answer

Can you take Octacosanol with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, octacosanol might have additive effects when used in combination with antidiabetes drugs.

Full Octacosanol + Glucagon answer

Can you take Oleic Acid with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oleic acid might increase the effects of antidiabetes drugs.

Full Oleic Acid + Glucagon answer

Can you take Onion with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use of antidiabetes drugs with onion may increase the risk of hypoglycemia.

Full Onion + Glucagon answer

Can you take Oregano with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.

Full Oregano + Glucagon answer

Can you take Oregon Grape with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Oregon grape might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full Oregon Grape + Glucagon answer

Can you take Padang Cassia with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Some clinical research shows that Padang cassia can reduce blood glucose levels in healthy patients and in patients with diabetes or impaire...

Full Padang Cassia + Glucagon answer

Can you take Parsley with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full Parsley + Glucagon answer

Can you take Pata De Vaca with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that pata de vaca may have hypoglycemic effects.

Full Pata De Vaca + Glucagon answer

Can you take Phaseolus Vulgaris with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Phaseolus vulgaris might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full Phaseolus Vulgaris + Glucagon answer

Can you take Phellodendron with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phellodendron may increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full Phellodendron + Glucagon answer

Can you take Phlorizin with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Phlorizin is a potent, nonselective inhibitor of SGLT1 and SGLT2.

Full Phlorizin + Glucagon answer

Can you take Picrorhiza with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from animal research suggests that an extract of picrorhiza can reduce fasting and non-fasting blood sugar levels.

Full Picrorhiza + Glucagon answer

Can you take Policosanol with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, policosanol might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.

Full Policosanol + Glucagon answer

Can you take Purple Nut Sedge with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from animal research suggests that purple nut sedge can reduce blood glucose levels.

Full Purple Nut Sedge + Glucagon answer

Can you take Quassia with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In animals, quassia extract reduced levels of fasting glucose.

Full Quassia + Glucagon answer

Can you take Quercetin with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of quercetin and antidiabetes drugs might increase the risk of hypoglycemia.

Full Quercetin + Glucagon answer

Can you take Radish with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, radish might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full Radish + Glucagon answer

Can you take Rauvolfia Vomitoria with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Rauvolfia vomitoria with antidiabetes drugs might increase the risk of hypoglycemia.

Full Rauvolfia Vomitoria + Glucagon answer

Can you take Red Sandalwood with Glucagon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research shows that an aqueous extra of red sandalwood bark reduces blood glucose levels.

Full Red Sandalwood + Glucagon answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Glucagon is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Glucagon, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Glucagon sits in 2 interaction categories. Open any one to see what the group means:

Antidiabetes Drugs 239 ingredients

Blood-sugar-lowering medications. Supplements that also lower glucose can push blood sugar too low when combined.

239 of the supplement ingredients on this page reach Glucagon through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Glucagon through this category.

About Glucagon

Glucagon nasal powder is an emergency treatment for severe low blood sugar (hypoglycemia) in people with diabetes.

Generic name: Glucagon  ·  Brand names: Glucagon, Baqsimi.

See the full Glucagon Nasal Powder drug information

Related: does Glucagon deplete any nutrients?

Glucagon has 2 reported nutrient associations in the research literature — see the Glucagon nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Glucagon

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Glucagon.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Glucagon & Supplements: Common Questions

What supplements interact with Glucagon?
In our interaction database, 256 supplement and herbal ingredients have an interaction with Glucagon on file — 2 rated major, 215 moderate, and 39 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Siberian Cocklebur, Activated Charcoal, American Ginseng.
Which Glucagon supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur and Activated Charcoal. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Glucagon?
That depends entirely on which supplement. The honest answer for Glucagon is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Glucagon have the same supplement interactions as Glucagon?
Yes — Glucagon, Baqsimi all contain Glucagon, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Glucagon deplete any vitamins or nutrients?
It might — Glucagon has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Glucagon nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Glucagon and my other medications?
This page covers Glucagon against supplements and herbal ingredients. Checking Glucagon against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Glucagon Nasal Powder drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.