Medication interaction hub

What Supplements Interact with Glucose?

Glucose brand name: IV Glucose. Every interaction below applies to the brands too.

256 Interactions 2 Major 215 Moderate 39 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Glucose? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Glucose against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Glucose given by IV raises a dangerously low blood sugar, and this list warrants real caution because most of its 256 ingredients pull the other way. Nearly all of them lower blood sugar on their own, working against the treatment and setting up another crash. Two rate major and come first: Siberian cocklebur has caused severe drops in blood sugar in humans, and activated charcoal can bind many medicines in the gut and cut how much reaches your body.

The other 215 moderate and 39 minor entries follow the same pattern, everyday herbs and foods with modest glucose-lowering effects. A few, niacin among them, raise blood sugar instead, complicating control from the other direction. If lows keep bringing you back for treatment, go through this page with your pharmacist. A smaller cluster can block absorption of pills you swallow, so keep those spaced well apart from any oral medicine.

— , Clinical Pharmacist · July 18, 2026

Major 2 Moderate 215 Minor 39 No known interaction 1,196

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Glucose: Top Interactions at a Glance

The Glucose supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 256 interacting ingredients — plus 1,196 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Glucose Combinations Today

The Glucose + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Lion's Mane Mushroom + Glucosei

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.

Read the full interaction Moderate Likelihood Possible Hibiscus Sabdariffa + Glucosei

Theoretically, taking Hibiscus sabdariffa with antidiabetes drugs might increase the risk of hypoglycemia.

Read the full interaction Moderate Likelihood Possible Eleuthero + Glucosei

Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.

Read the full interaction Moderate Likelihood Possible Hollyhock + Glucosei

Animal and in vitro research shows that hollyhock flower extracts might lower blood glucose levels.

Read the full interaction Moderate Likelihood Possible Agrimony + Glucosei

Theoretically, taking agrimony with antidiabetes drugs might increase the risk of hypoglycemia.

Read the full interaction Moderate Likelihood Possible Anise + Glucosei

Theoretically, anise seed might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Glucose

All 1,452 ingredients in our database, ranked by severity — 256 with a Glucose interaction on file and 1,196 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Glucose?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Lion's Mane Mushroom with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.

Full Lion's Mane Mushroom + Glucose answer

Can you take Hibiscus Sabdariffa with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Hibiscus sabdariffa with antidiabetes drugs might increase the risk of hypoglycemia.

Full Hibiscus Sabdariffa + Glucose answer

Can you take Eleuthero with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.

Full Eleuthero + Glucose answer

Can you take Hollyhock with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal and in vitro research shows that hollyhock flower extracts might lower blood glucose levels.

Full Hollyhock + Glucose answer

Can you take Agrimony with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking agrimony with antidiabetes drugs might increase the risk of hypoglycemia.

Full Agrimony + Glucose answer

Can you take Terminalia Chebula with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypog...

Full Terminalia Chebula + Glucose answer

Can you take Theaflavin with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In an animal diabetic model, giving theaflavin reduced fasting blood glucose, with an effect comparable to metformin.

Full Theaflavin + Glucose answer

Can you take Tinospora Cordifolia with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full Tinospora Cordifolia + Glucose answer

Can you take Tiratricol with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tiratricol might interfere with blood glucose control.

Full Tiratricol + Glucose answer

Can you take Tragacanth with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.

Full Tragacanth + Glucose answer

Can you take Tribulus with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.

Full Tribulus + Glucose answer

Can you take Tronadora with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of tronadora and antidiabetes drugs might increase the risk of hypoglycemia.

Full Tronadora + Glucose answer

Can you take Turkey Tail Mushroom with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking turkey tail mushroom with antidiabetes drugs might increase the risk of hypoglycemia.

Full Turkey Tail Mushroom + Glucose answer

Can you take Turmeric with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking turmeric with antidiabetes drugs might increase the risk of hypoglycemia.

Full Turmeric + Glucose answer

Can you take Weight Watchers Diet with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Following the Weight Watchers diet while taking antidiabetes drugs may increase the risk of hypoglycemia.

Full Weight Watchers Diet + Glucose answer

Can you take Wheatgrass with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking wheatgrass with antidiabetes drugs might lower blood glucose levels and increase the risk of hypoglycemia.

Full Wheatgrass + Glucose answer

Can you take White Horehound with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from animal research suggests that white horehound might lower blood glucose.

Full White Horehound + Glucose answer

Can you take White Mulberry with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Full White Mulberry + Glucose answer

Can you take White Pepper with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from animal research suggests that piperine, a constituent of white pepper, reduces blood glucose levels.

Full White Pepper + Glucose answer

Can you take Winter Cherry with Glucose?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In animal diabetic models, winter cherry extract decreases blood glucose.

Full Winter Cherry + Glucose answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Glucose is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Glucose, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Glucose sits in 3 interaction categories. Open any one to see what the group means:

Antidiabetes Drugs 239 ingredients

Blood-sugar-lowering medications. Supplements that also lower glucose can push blood sugar too low when combined.

239 of the supplement ingredients on this page reach Glucose through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Glucose through this category.

Sodium-Glucose Co-Transporter 2 (Sglt2) Inhibitors 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Glucose through this category.

Related: does Glucose deplete any nutrients?

Glucose has 1 reported nutrient association in the research literature — see the Glucose nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Glucose

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Glucose.

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Pharmacist Counseling Corner

Glucose & Supplements: Common Questions

What supplements interact with Glucose?
In our interaction database, 256 supplement and herbal ingredients have an interaction with Glucose on file — 2 rated major, 215 moderate, and 39 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Siberian Cocklebur, Activated Charcoal, American Ginseng.
Which Glucose supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur and Activated Charcoal. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Glucose?
That depends entirely on which supplement. The honest answer for Glucose is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like IV Glucose have the same supplement interactions as Glucose?
Yes — IV Glucose all contain Glucose, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Glucose deplete any vitamins or nutrients?
It might — Glucose has 1 reported nutrient-depletion association in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Glucose nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Glucose and my other medications?
This page covers Glucose against supplements and herbal ingredients. Checking Glucose against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.