What Supplements Interact with Zuclopenthizol?
Zuclopenthizol brand name: Clopixol. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Zuclopenthizol? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Zuclopenthizol against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
What is this?
The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.Zuclopenthizol (Clopixol) is a sedating antipsychotic, and most of the 205 supplement interactions on record push in that same direction. Seventy-eight ingredients, including everyday alcohol and kava, deepen drowsiness, and the worst of them can dangerously slow breathing. Fifteen entries carry a major rating, and I'd want anyone taking this medicine to know those fifteen before adding anything, particularly products sold for sleep or calm, since those are exactly what people on a sedating drug tend to reach for.
The remainder run milder, 178 moderate and 12 minor, and they follow a few patterns: roughly 60 ingredients can change how the body clears the drug, 20 add to sun sensitivity, and a cluster of 13, grapefruit among them, can stretch the heart's electrical rhythm, a risk antipsychotics can already carry. Notice that beer, wine, and grapefruit all appear here. Ordinary groceries matter on this list as much as herbs do.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Zuclopenthizol: Top Interactions at a Glance
The Zuclopenthizol supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 205 interacting ingredients — plus 1,247 more checked with no known interaction. See the complete ranked list.
The Most-Checked Zuclopenthizol Combinations Today
The Zuclopenthizol + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full interaction Moderate Likelihood Possible Cordyceps + ZuclopenthizoliTheoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full interaction Moderate Likelihood Possible Jiaogulan + ZuclopenthizoliTheoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Read the full interaction Moderate Likelihood Possible Cannabichromene (cbc) + ZuclopenthizoliUsing cannabichromene with drugs that have sedative properties may cause additive therapeutic and adverse effects.
Read the full interaction Moderate Likelihood Possible Fermented Wheat Germ Extract + ZuclopenthizoliTheoretically, concomitant use of fermented wheat germ extract with serotonergic medications may increase the risk of serotonergic adverse effects.
Read the full interaction Major Likelihood Probable Arsenic + ZuclopenthizoliArsenic trioxide can prolong the QT interval.
Read the full interactionEvery Supplement Checked Against Zuclopenthizol
All 1,452 ingredients in our database, ranked by severity — 205 with a Zuclopenthizol interaction on file and 1,247 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
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Beer Likely
What it is: Beer is an alcoholic beverage that contains some minerals, B vitamins, and plant compounds from hops and grain, but it is not a health suppl...
Concomitant use may increase sedative and other adverse effects.
Read the full Beer + Zuclopenthizol interactionWine Likely
What it is: Wine is an alcoholic beverage made from fermented grapes and is not a true dietary supplement or medicine.
Concomitant use may increase sedative and other adverse effects.
Read the full Wine + Zuclopenthizol interaction1,4-butanediolOne Comma Four, one Four Bdo, one Four Bee, +1 more Probable
What it is: 1,4-butanediol is a toxic industrial chemical, not a safe dietary supplement.
Theoretically, concomitant use of 1,4-butanediol with CNS depressants may potentiate respiratory and CNS depression.
Read the full 1,4-butanediol + Zuclopenthizol interactionArsenic Probable
What it is: Arsenic is a naturally occurring element that is toxic in its inorganic form, and it is not a supplement you should take to improve your hea...
Arsenic trioxide can prolong the QT interval.
Read the full Arsenic + Zuclopenthizol interactionCesium Probable
What it is: Cesium chloride is a mineral salt sold as an alternative cancer therapy ('high pH therapy'), but there is no reliable scientific evidence th...
Theoretically, taking cesium concomitantly with other drugs that prolong the QT interval may increase the risk of ventricular arrhythmias and death.
Read the full Cesium + Zuclopenthizol interactionEphedraEphedra Distachya, belcho, cao Mahuang, +13 more Probable
What it is: Ephedra (ma huang) contains powerful stimulants like ephedrine that affect the heart and nervous system.
Theoretically, ephedra might have an additive effect with drugs that prolong the QT interval.
Read the full Ephedra + Zuclopenthizol interactionGamma-hydroxybutyrate (ghb) Probable
What it is: GHB (gamma-hydroxybutyrate) is a powerful central nervous system depressant that is NOT a safe dietary supplement.
GHB may increase the risk of serious CNS and respiratory depression.
Read the full Gamma-hydroxybutyrate (ghb) + Zuclopenthizol interactionGrapefruitCitrus Paradisi Probable
What it is: Grapefruit is a nutritious citrus fruit rich in vitamin C and other nutrients, and it is generally safe to eat.
Grapefruit or grapefruit juice, especially if consumed in large amounts, can cause additive QT interval prolongation when taken with QT interval-prolonging drugs, potentially increasing the risk of ventricular arrhythmias.
Read the full Grapefruit + Zuclopenthizol interactionIndian SnakerootRauvolfia Serpentina, ajmaline, alseroxylon, +16 more Probable
What it is: Indian snakeroot is a traditional Ayurvedic plant that contains reserpine, a compound with real blood-pressure-lowering and sedative effects...
Theoretically, concomitant use might increase the risk of adverse effects.
Read the full Indian Snakeroot + Zuclopenthizol interactionKavaPiper Methysticum, ava Pepper, ava Root, +20 more Probable
What it is: Kava is a Pacific Island plant traditionally used to promote relaxation and ease anxiety, and some studies suggest it may help mild anxiety.
Combining kava with CNS depressants can have additive sedative effects.
Read the full Kava + Zuclopenthizol interactionL-tryptophanL-triptofano, l-trypt, l-tryptophane, +1 more Probable
What it is: L-tryptophan is an essential amino acid the body uses to make serotonin and melatonin, and people take it to support sleep and mood.
Theoretically, concomitant use of L-tryptophan with CNS depressants might cause additive sedative effects.
Read the full L-tryptophan + Zuclopenthizol interactionLithiumCarbonate De Lithium, citrate De Lithium, lithium Aspartate, +8 more Probable
What it is: Lithium is a naturally occurring metal that, in prescription form (lithium carbonate or citrate), is an FDA-approved, well-proven treatment...
Theoretically, taking lithium supplements with serotonergic drugs might both mask and increase the risk of serotonin syndrome.
Read the full Lithium + Zuclopenthizol interactionRauvolfia Vomitoria Probable
What it is: Rauvolfia vomitoria is an African shrub whose root contains powerful alkaloids, including reserpine, that have historically been used for hi...
Theoretically, concomitant use might increase the risk of adverse effects.
Read the full Rauvolfia Vomitoria + Zuclopenthizol interactionSida CordifoliaAbutilon En Épi, bala, bariar, +15 more Probable
What it is: Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant.
Theoretically, Sida cordifolia might increase the risk of additive QT interval prolongation when taken with QT interval-prolonging drugs.
Read the full Sida Cordifolia + Zuclopenthizol interactionAmerican HelleboreVeratrum Viride, american Veratrum, american White Hellebore, +11 more Possible
What it is: American Hellebore (Veratrum viride) is a highly poisonous plant whose root contains toxic alkaloids that can cause dangerous drops in heart...
American hellebore, also known as Veratrum viride, contains alkaloids that can potentially prolong the QT interval on an electrocardiogram (ECG).
Read the full American Hellebore + Zuclopenthizol interactionAyahuascaAppane, ayahoasca, caapi, +19 more Probable
What it is: Ayahuasca is a powerful psychoactive brew that combines a DMT-containing plant with a vine that allows the DMT to take effect, causing inten...
Theoretically, ayahuasca might increase plasma concentrations of CYP2D6 substrates.
Read the full Ayahuasca + Zuclopenthizol interactionBergamotCitrus Bergamia, aceite De Bergamota, bergamot, +8 more Probable
What it is: Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some...
Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Read the full Bergamot + Zuclopenthizol interactionChenopodium OilAceite De Paico, aceite De Quenopodio, american Wormseed, +15 more Probable
What it is: Chenopodium oil is a strong-smelling essential oil from the epazote plant that was historically used to treat intestinal worms.
Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.
Read the full Chenopodium Oil + Zuclopenthizol interactionChlorophyllChlorophylle, chlorophylle A, chlorophylle B, +3 more Probable
What it is: Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin.
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Zuclopenthizol interactionChlorophyllinChloresium, chlorophylline, chlorophylline De Cuivre Sodique, +6 more Probable
What it is: Chlorophyllin is a water-soluble, semi-synthetic form of chlorophyll most often used to help control body and fecal odor and to support woun...
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Chlorophyllin + Zuclopenthizol interactionGoldensealHydrastis Canadensis, chinese Goldenseal, eye Balm, +14 more Probable
What it is: Goldenseal is a popular North American herb that contains berberine, a compound studied for antimicrobial effects.
Goldenseal might increase serum levels of drugs metabolized by CYP2D6.
Read the full Goldenseal + Zuclopenthizol interactionMasterwortHeracleum Sphondylium, berce Commune, berce Laineuse, +9 more Probable
What it is: Masterwort (Heracleum sphondylium), a plant in the carrot family, has a long folk-medicine history for digestion, nerves, and skin.
The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effects.
Read the full Masterwort + Zuclopenthizol interactionSyrian Rue Probable
What it is: Syrian Rue (Peganum harmala) is a traditional plant whose seeds contain potent compounds called harmala alkaloids, including MAO-inhibiting...
Theoretically, Syrian rue might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Syrian Rue + Zuclopenthizol interactionWild CarrotDaucus Carota, beesnest Plant, bird's Nest Root, +10 more Probable
What it is: Wild carrot is a traditional herb (the wild ancestor of the garden carrot) used mostly for urinary, digestive, and menstrual complaints.
Theoretically, concomitant use might result in increased photosensitivity.
Read the full Wild Carrot + Zuclopenthizol interactionYerba MansaAnemopsis Californica, anemopsis De Californie, lizard's Tail, +3 more Probable
What it is: Yerba mansa is a traditional Southwestern and Mexican medicinal plant used for sore throats, skin problems, and infections.
Theoretically, concomitant use might cause additive or prolonged sedative effects.
Read the full Yerba Mansa + Zuclopenthizol interaction1,3-dmaaDmaa, dimethylamylamine Possible
What it is: DMAA (1,3-dimethylamylamine) is a synthetic stimulant that was sold in pre-workout and weight-loss supplements but has been linked to seriou...
1,3-DMAA strongly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.
Read the full 1,3-dmaa + Zuclopenthizol interaction5-htp5 Hydroxy-tryptophan, 5 Hydroxy-tryptophane, 5-hydroxytryptophan, +9 more Possible
What it is: 5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches.
Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
Read the full 5-htp + Zuclopenthizol interactionAcacia RigidulaVachellia Rigidula, acacia Rigidula, acaciopsis Rigidula, +3 more Possible
What it is: Acacia rigidula is a shrub from Texas and Mexico that is marketed in weight-loss and energy supplements.
Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP2D6 substrates.
Read the full Acacia Rigidula + Zuclopenthizol interactionAcetyl-l-carnitineAcetil-l-carnitina, acetyl Carnitine, acétyl Carnitine, +6 more Possible
What it is: Acetyl-L-carnitine is a form of the amino acid carnitine that the body uses to help produce energy in cells.
Theoretically, acetyl-L-carnitine might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders, when taken with serotonergic drugs.
Read the full Acetyl-l-carnitine + Zuclopenthizol interactionActive Hexose Correlated Compound (ahcc) Possible
What it is: AHCC is a proprietary mushroom-derived supplement promoted mainly for immune support and to help people tolerate cancer treatment.
Theoretically, AHCC might increase levels of drugs metabolized by CYP2D6.
Read the full Active Hexose Correlated Compound (ahcc) + Zuclopenthizol interactionAdrueCyperus Articulatus, chintul, cyperus, +5 more Possible
What it is: Adrue (Cyperus articulatus) is a sedge whose rhizome has long been used in traditional medicine for nausea and other stomach complaints, and...
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Adrue + Zuclopenthizol interactionAlbizia JulibrissinAlbizia Julibrissin, arbre De Sois, federbaum, +16 more Possible
What it is: Albizia julibrissin (Persian silk tree, He Huan) is a plant used in traditional Chinese medicine, mainly the flower and bark, for calming th...
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Albizia Julibrissin + Zuclopenthizol interactionAlfalfaMedicago Sativa, feuille De Luzerne, grand Trèfle, +9 more Possible
What it is: Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence f...
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa + Zuclopenthizol interactionAmerican GinsengPanax Quinquefolius, anchi Ginseng, baie Rouge, +14 more Possible
What it is: American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar.
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Zuclopenthizol interactionAndrographisAndrographis Paniculata, bhunimba, bidara, +19 more Possible
What it is: Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms an...
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis + Zuclopenthizol interactionAngelica ArchangelicaAmerican Angelica, angelicae Fructus, angelicae Herba, +12 more Possible
What it is: Angelica archangelica is a tall aromatic herb used traditionally for digestive complaints, poor appetite, and to flavor foods and liqueurs.
Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions.
Read the full Angelica Archangelica + Zuclopenthizol interactionArrachChenopodium Vulvaria, arroche Puante, chénopode Fétide, +11 more Possible
What it is: Arrach (Chenopodium vulvaria) is a strong-smelling European herb that has been used in traditional folk medicine, mainly for menstrual and n...
Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photosensitivity.
Read the full Arrach + Zuclopenthizol interactionAshwagandhaWithania Somnifera, ajagandha, amangura, +17 more Possible
What it is: Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, thoug...
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha + Zuclopenthizol interactionAstragalusAstragale, astragale à Feuilles De Réglisse, astragale Queue-de-renard, +15 more Possible
What it is: Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with str...
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Zuclopenthizol interactionBay LeafLaurus Nobilis, bay, bay Laurel, +17 more Possible
What it is: Bay leaf is a common culinary herb that is safe in the small amounts used in cooking.
Theoretically, taking bay leaf in large amounts may enhance the therapeutic and adverse effects of sedatives.
Read the full Bay Leaf + Zuclopenthizol interactionBee VenomApis Venenum Purum, apitoxin, apitoxine, +3 more Possible
What it is: Bee venom is a complex mixture of proteins and other compounds taken from honeybees and used in traditional medicine for pain and inflammati...
Bee venom might stimulate immune system activity.Theoretically, bee venom might interfere with immunosuppressant therapy.
Read the full Bee Venom + Zuclopenthizol interactionBerberineAlcaloïde De Berbérine, berberina, berbérine, +5 more Possible
What it is: Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of res...
Theoretically, berberine might increase the sedative effects of CNS depressants.
Read the full Berberine + Zuclopenthizol interactionBeta-glucans Possible
What it is: Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast.
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucans + Zuclopenthizol interactionBeta-methylphenethylamine (bmpea) Possible
What it is: Beta-methylphenethylamine (BMPEA) is a synthetic stimulant chemically similar to amphetamine that has been found in some weight-loss and spo...
Theoretically, BMPEA might increase the levels and clinical effects of CYP2D6 substrates.
Read the full Beta-methylphenethylamine (bmpea) + Zuclopenthizol interactionBiofeedback Possible
What it is: Biofeedback is a mind-body technique, not an herb or supplement.
There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.
Read the full Biofeedback + Zuclopenthizol interactionBishop's WeedAmmi Majus, Élevé, ammi Inodore, +12 more Possible
What it is: Bishop's Weed (Ammi majus) is a flowering plant whose seeds contain natural light-sensitizing compounds called psoralens, which have been st...
Bishop's weed constituents seem to cause photosensitivity.
Read the full Bishop's Weed + Zuclopenthizol interactionBitter AlmondPrunus Amygdalus, almendra Amarga, almendro Amargo, +13 more Possible
What it is: Bitter almond is a variety of almond that contains amygdalin, a compound the body converts into cyanide, making it potentially poisonous.
Theoretically, bitter almond oil may have additive effects with other CNS depressants.
Read the full Bitter Almond + Zuclopenthizol interactionBitter OrangeCitrus Aurantium, aurantii Fructus, aurantium, +17 more Possible
What it is: Bitter orange is a citrus fruit whose extracts contain synephrine, a mild stimulant often added to weight-loss and energy supplements.
Theoretically, bitter orange might have an additive effect when combined with drugs that prolong the QT interval, potentially increasing the risk of ventricular arrhythmias.
Read the full Bitter Orange + Zuclopenthizol interactionBlack CohoshActaea Racemosa, baie D'actée, baneberry, +10 more Possible
What it is: Black cohosh is a North American plant most often used to ease menopause symptoms like hot flashes, but the research is mixed and far from s...
Some research suggests that black cohosh might inhibit CYP2D6, but there is conflicting evidence.
Read the full Black Cohosh + Zuclopenthizol interactionBlack Hoof MushroomPhellinus Linteus, black Hoof Fungus, mesima, +5 more Possible
What it is: Black Hoof Mushroom (Phellinus linteus) is a medicinal mushroom long used in East Asian traditional medicine, mainly for immune support.
Theoretically, black hoof mushroom might reduce the effects of immunosuppressant medications.
Read the full Black Hoof Mushroom + Zuclopenthizol interactionBlack PepperPiper Nigrum, black Peppercorn, extrait De Poivre, +23 more Possible
What it is: Black pepper is a common kitchen spice that is generally safe in the amounts used in food.
Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
Read the full Black Pepper + Zuclopenthizol interactionBlack SeedNigella Sativa, black Caraway, black Cumin, +18 more Possible
What it is: Black seed (Nigella sativa) is a traditional spice and remedy that has been studied for asthma, blood sugar, cholesterol, and blood pressure...
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Black Seed + Zuclopenthizol interactionBlood Irradiation Therapy Possible
What it is: Blood Irradiation Therapy is a medical procedure—not a dietary supplement or herb—in which blood is exposed to ultraviolet or laser light, e...
Clinical research suggests that blood irradiation therapy may stimulate immune function in some patients.
Read the full Blood Irradiation Therapy + Zuclopenthizol interactionBlue-green AlgaeAfa, algae, algues Bleu-vert Du Lac Klamath, +16 more Possible
What it is: Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutri...
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Blue-green Algae + Zuclopenthizol interactionBoswellia SerrataBoswellia Serrata, arbre à Oliban Indien, boswella, +10 more Possible
What it is: Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation.
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Boswellia Serrata + Zuclopenthizol interactionBupleurumBei Chai Hu, bupleuri, bupleurum Chinese, +12 more Possible
What it is: Bupleurum (Chai Hu) is a root used in traditional Chinese medicine, usually as part of multi-herb formulas, for liver, digestive, and fever-...
Theoretically, bupleurum might decrease the effects of immunosuppressants.
Read the full Bupleurum + Zuclopenthizol interactionCajeput OilMelaleuca Leucadendra, aceite De Cajeput, cajeputi Aetheroleum, +10 more Possible
What it is: Cajeput oil is an aromatic essential oil traditionally used for aches, congestion, and minor skin complaints, but solid human evidence for t...
Evidence from in vitro research suggests that cajeput leaf extract can inhibit cytochrome P450 2D6 (CYP2D6) by approximately 30%.
Read the full Cajeput Oil + Zuclopenthizol interactionCalamusAcorus Calamus, acore Calame, acore Odorant, +20 more Possible
What it is: Calamus is a swamp plant with a long history in Ayurvedic and traditional Chinese medicine, mostly for digestive and nervous-system complain...
Theoretically, concurrent use of CNS depressants and calamus might have an additive effect and increase the risk of sedative effects.
Read the full Calamus + Zuclopenthizol interactionCalifornia PoppyEschscholzia Californica, amapola De California, pavot D'amérique, +4 more Possible
What it is: California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs.
Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Read the full California Poppy + Zuclopenthizol interactionCannabichromene (cbc)Cannabichrome, pentylcannabichromene, cannabinochromene Possible
What it is: Cannabichromene (CBC) is a non-intoxicating cannabinoid found in the cannabis plant that is being studied for possible pain, anti-inflammato...
Using cannabichromene with drugs that have sedative properties may cause additive therapeutic and adverse effects.
Read the full Cannabichromene (cbc) + Zuclopenthizol interactionCannabidiol (cbd) Possible
What it is: CBD is a compound from the cannabis (hemp) plant that does not cause a 'high.' It has strong evidence only for certain rare seizure disorder...
Theoretically, cannabidiol might have additive effects if used with other CNS depressants.
Read the full Cannabidiol (cbd) + Zuclopenthizol interactionCannabisCannabis Sativa, anashca, banji, +25 more Possible
What it is: Cannabis contains many active compounds, mainly THC (which causes a 'high') and CBD (which does not).
Theoretically, cannabis might have additive effects if used with other CNS depressants.
Read the full Cannabis + Zuclopenthizol interactionCarawayCarum Carvi, alcaravea, anis Canadien, +20 more Possible
What it is: Caraway is a common cooking spice that has long been used to ease gas, bloating, and indigestion.
Theoretically, caraway might increase the effects and adverse effects of CNS depressants.
Read the full Caraway + Zuclopenthizol interactionCat's ClawGriffe Du Chat, hawk's Claw, liane Du Pérou, +4 more Possible
What it is: Cat's claw is a South American vine traditionally used for inflammation, joint pain, and immune support.
Theoretically, cat's claw might interfere with immunosuppressive therapy.
Read the full Cat's Claw + Zuclopenthizol interactionCatechuBlack Catechu, acacia Catechu: Acacia à Cachou, acacia Catechu Heartwood Extract, +17 more Possible
What it is: Catechu is an astringent extract made from the heartwood of the Acacia (Senegalia) catechu tree, used traditionally for mouth sores, sore th...
Theoretically, catechu might interfere with immunosuppressant therapy.
Read the full Catechu + Zuclopenthizol interactionCatnipNepeta Cataria, cataire, catmint, +8 more Possible
What it is: Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research suppor...
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Zuclopenthizol interactionCeylon Leadwort Possible
What it is: Ceylon Leadwort (Plumbago zeylanica) is a plant long used in Ayurvedic and other traditional medicine systems, mainly for digestion, skin pr...
Plumbagin, a constituent of Ceylon leadwort, has been shown to inhibit cytochrome P450 2D6 (CYP2D6) in vitro.
Read the full Ceylon Leadwort + Zuclopenthizol interactionChaga Possible
What it is: Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support.
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Zuclopenthizol interactionChlorellaChlorella Pyrenoidosa, algue Verte D'eau Douce, bulgarian Chlorella, +12 more Possible
What it is: Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small stud...
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Zuclopenthizol interactionCilantro Possible
What it is: Cilantro is the leafy part of the Coriandrum sativum plant and is widely eaten as a food, where it is considered safe for most people.
Evidence from in vitro research suggests that coriandrin, a constituent of cilantro, has photosensitizing effects.
Read the full Cilantro + Zuclopenthizol interactionCinchonaCinchona Calisaya, arbol De La Quina, bois Aux Fièvres, +14 more Possible
What it is: Cinchona bark is the natural source of quinine and has been used for centuries to treat malaria and fever, but the bark itself is not standa...
Theoretically, taking cinchona might inhibit cytochrome P450 2D6 (CYP2D6) and increase levels of drugs metabolized by this enzyme.
Read the full Cinchona + Zuclopenthizol interactionCloveSyzygium Aromaticum, bourgeon Floral De Clou De Girofle, bouton Floral De Clou De Girofle, +12 more Possible
What it is: Clove is a common cooking spice that is also used in traditional medicine, especially as a topical numbing agent for tooth pain thanks to it...
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Clove + Zuclopenthizol interactionCnidiumCnidium Monnieri, cnidii Fructus, cnidii Monnieri Fructus, +10 more Possible
What it is: Cnidium is the dried fruit of an Asian plant long used in traditional Chinese medicine, mostly for skin problems and sexual health.
In laboratory research, cnidium has been shown to have sedative and hypnotic effects, possibly related to constituent coumarins.
Read the full Cnidium + Zuclopenthizol interactionCordycepsOphiocordyceps Sinensis, caterpillar Fungus, caterpillar Mushroom, +10 more Possible
What it is: Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support.
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Zuclopenthizol interactionCorianderCoriandrum Sativum, coriander Essential Oil, coriandre, +5 more Possible
What it is: Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints...
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Coriander + Zuclopenthizol interactionCorn PoppyPapaver Rhoeas, amapola, common Poppy, +18 more Possible
What it is: Corn poppy is a red-flowered plant traditionally used in teas and syrups for cough, sleep, and mild pain.
Theoretically, concomitant use of corn poppy with CNS depressants might increase the risk of sedation.
Read the full Corn Poppy + Zuclopenthizol interactionCorydalis Yanhusuo Possible
What it is: Corydalis yanhusuo is a traditional Chinese herb used mainly for pain.
Theoretically, Corydalis yanhusuo might increase the sedative effects of CNS depressants.
Read the full Corydalis Yanhusuo + Zuclopenthizol interactionCowhage Possible
What it is: Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine.
Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Read the full Cowhage + Zuclopenthizol interactionDelta-9-tetrahydrocannabinol (thc)Bho, black Glass, budder, +9 more Possible
What it is: THC is the main mind-altering compound in cannabis and is best known for causing a 'high.' A prescription form (dronabinol) is approved for...
Theoretically, THC might have additive effects if used with other CNS depressants.
Read the full Delta-9-tetrahydrocannabinol (thc) + Zuclopenthizol interactionDendrobium Possible
What it is: Dendrobium is a group of orchids long used in traditional Chinese medicine, often to moisten the body and as a general tonic.
The dendrobium constituent dendrobine is reported to have convulsant effects.
Read the full Dendrobium + Zuclopenthizol interactionEchinaceaAmerican Cone Flower, black Sampson, black Susans, +7 more Possible
What it is: Echinacea is a popular herb taken to help prevent or shorten the common cold, but study results are mixed and the overall benefit appears sm...
Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.
Read the full Echinacea + Zuclopenthizol interactionElderberrySambucus Nigra, arbre De Judas, baccae, +15 more Possible
What it is: Elderberry is a popular herbal supplement, mainly taken to help with colds and flu.
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Zuclopenthizol interactionElecampaneAlant, aunée, aunée Officinale, +17 more Possible
What it is: Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion.
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Elecampane + Zuclopenthizol interactionEleutheroEleutherococcus Senticosus, acanthopanax Obovatus, ciwujia Root, +13 more Possible
What it is: Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress.
Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Read the full Eleuthero + Zuclopenthizol interactionEnglish IvyHedera Helix, common Ivy, gum Ivy, +9 more Possible
What it is: English ivy leaf extract is most commonly used in cough and cold syrups to help loosen mucus and ease coughing, and it is a popular ingredie...
Theoretically, English ivy might increase the levels of drugs metabolized by CYP2D6.
Read the full English Ivy + Zuclopenthizol interactionErgotClaviceps Purpurea, cockspur Rye, cornezuelo, +7 more Possible
What it is: Ergot is a toxic fungus that grows on rye and contains powerful chemicals (ergot alkaloids) that strongly narrow blood vessels and squeeze t...
Certain ergot alkaloids, such as dihydroergotamine, act as serotonin agonists.
Read the full Ergot + Zuclopenthizol interactionEuropean BarberryBerberis Vulgaris, agracejo, barberry, +15 more Possible
What it is: European barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolat...
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full European Barberry + Zuclopenthizol interactionEuropean MistletoeViscum Album, all-heal, banda, +23 more Possible
What it is: European mistletoe is a parasitic plant most studied as an injectable extract used alongside conventional cancer care in some European count...
Theoretically, European mistletoe might decrease the effectiveness of immunosuppressants.
Read the full European Mistletoe + Zuclopenthizol interactionEvodia Possible
What it is: Evodia is a fruit used in traditional Chinese medicine, most often for digestive complaints, headaches, and menstrual pain.
Theoretically, evodia might have an additive effect with drugs that prolong the QT interval, potentially increasing the risk of ventricular arrhythmias.
Read the full Evodia + Zuclopenthizol interactionFalse UnicornChamaelirium Luteum, alétris, blazing Star, +9 more Possible
What it is: False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concern...
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Zuclopenthizol interactionFermented Milk Possible
What it is: Fermented milk is a food made by culturing milk with helpful bacteria or yeast, and it provides protein, calcium, and probiotics.
Theoretically, fermented milk might decrease the effects of immunosuppressants.
Read the full Fermented Milk + Zuclopenthizol interactionFermented Wheat Germ Extract Possible
What it is: Fermented wheat germ extract is a supplement made by fermenting wheat germ with yeast, and it is most often marketed for people going throug...
Theoretically, concomitant use of fermented wheat germ extract with serotonergic medications may increase the risk of serotonergic adverse effects.
Read the full Fermented Wheat Germ Extract + Zuclopenthizol interactionFever BarkAlstonia Constricta, alstonia Bark, australian Febrifuge, +10 more Possible
What it is: Fever bark is the bark of the Australian tree Alstonia constricta, used in traditional medicine for fever, diarrhea, and infections.
Theoretically, fever bark might increase the levels and clinical effects of CYP2D6 substrates.
Read the full Fever Bark + Zuclopenthizol interactionFeverfewTanacetum Parthenium, altamisa, bachelor's Buttons, +13 more Possible
What it is: Feverfew is a daisy-family herb best known for migraine prevention, where some studies suggest it may modestly lower how often migraines occ...
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew + Zuclopenthizol interactionFig Possible
What it is: Fig (Ficus carica) is a common fruit that has long been used as a gentle food remedy for constipation, and its leaves are used traditionally...
Theoretically, fig might increase the risk of photosensitivity when used in combination with photosensitizing drugs.
Read the full Fig + Zuclopenthizol interactionFo-ti Possible
What it is: Fo-ti (He Shou Wu) is a root used in traditional Chinese medicine, often promoted for healthy aging and hair.
Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Fo-ti + Zuclopenthizol interactionFulvic Acid Possible
What it is: Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and ov...
Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Read the full Fulvic Acid + Zuclopenthizol interactionGalacto-oligosaccharides (gos) Possible
What it is: Galacto-oligosaccharides (GOS) are a type of prebiotic fiber that feed the helpful bacteria in your gut.
Theoretically, GOS might reduce the effects of immunosuppressants.
Read the full Galacto-oligosaccharides (gos) + Zuclopenthizol interactionGalphimia GlaucaGalphimia Glauca, calderona Amarilla, flor Estrella, +2 more Possible
What it is: Galphimia glauca is a shrub from Mexico and Central America that has been studied mainly for anxiety, with some small clinical trials sugges...
Theoretically, taking Galphimia glauca with CNS depressants may increase the risk of sedation.
Read the full Galphimia Glauca + Zuclopenthizol interactionGamma Butyrolactone (gbl)2-3 Dihydro Furanone Possible
What it is: Gamma butyrolactone (GBL) is a toxic industrial solvent, not a dietary supplement, and the body converts it into GHB, a powerful and dangero...
Theoretically, concomitant use of GBL with CNS depressants may potentiate respiratory and CNS depression.
Read the full Gamma Butyrolactone (gbl) + Zuclopenthizol interactionGarciniaGarcinia Gummi-gutta, acide Hydroxycitrique, ahc, +11 more Possible
What it is: Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control.
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia + Zuclopenthizol interactionGerman ChamomileMatricaria Recutita, blue Chamomile, camomèle, +12 more Possible
What it is: German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints.
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full German Chamomile + Zuclopenthizol interactionGinkgoGinkgo Biloba, abricot Argenté Japonais, adiantifolia, +13 more Possible
What it is: Ginkgo is one of the world's most popular herbal supplements, mostly taken to support memory and circulation.
Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.
Read the full Ginkgo + Zuclopenthizol interactionGlyconutrients Possible
What it is: Glyconutrients are supplements containing certain sugar molecules (monosaccharides) that marketers claim are essential for cell communicatio...
Evidence from in vitro research suggests that glyconutrients stimulate certain immune responses.
Read the full Glyconutrients + Zuclopenthizol interactionGojiLycium Chinense, lycium Barbarum, barberry Matrimony Vine, +15 more Possible
What it is: Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food.
Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
Read the full Goji + Zuclopenthizol interactionGotu KolaCentella Asiatica, asiatic Pennywort, brahma-buti, +12 more Possible
What it is: Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memor...
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola + Zuclopenthizol interactionGrapeVitis Vinifera, activin, black Grape Raisins, +10 more Possible
What it is: Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support h...
Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
Read the full Grape + Zuclopenthizol interactionGreater CelandineChelidonium Majus, bai Qu Cai, celandine, +9 more Possible
What it is: Greater celandine is a traditional herb most often promoted for digestive and gallbladder complaints, but solid human evidence for any use i...
Research in vitro shows that chelidonine, a constituent of greater celandine, inhibits cytochrome P450 2D6 (CYP2D6) enzyme activity.
Read the full Greater Celandine + Zuclopenthizol interactionGriffonia SimplicifoliaBandeiraea Simplicifolia Possible
What it is: Griffonia simplicifolia is a West African shrub whose seeds are a natural source of 5-HTP, a building block of the brain chemical serotonin.
Theoretically, taking Griffonia simplicifolia seed extract with CNS depressants might increase the risk of additive CNS depression.
Read the full Griffonia Simplicifolia + Zuclopenthizol interactionGuarumoCecropia Obtusifolia, chancarro, grayumbo, +9 more Possible
What it is: Guarumo (Cecropia obtusifolia) is a tropical tree used in Latin American traditional medicine, most often as a leaf tea for diabetes and hig...
In an animal study, an aqueous extract of guarumo depressed the central nervous system, inducing significant motor incoordination and muscle relaxant activity.
Read the full Guarumo + Zuclopenthizol interactionHawaiian Baby WoodroseArgyreia Nervosa, baby Hawaiian Woodrose, baby Woodrose, +11 more Possible
What it is: Hawaiian Baby Woodrose seeds contain LSD-like compounds and are most often used recreationally to cause hallucinations, not as a safe or pro...
Theoretically, concomitant use may increase the risk for serotonergic adverse effects.
Read the full Hawaiian Baby Woodrose + Zuclopenthizol interactionHesperidinAlpha-glucosyl Hesperidin, alpha-glucosylhesperidin, bioflavonoid, +8 more Possible
What it is: Hesperidin is a flavonoid found in citrus fruits that is often combined with diosmin and used for vein and circulation problems like hemorrh...
Theoretically, concomitant use with CNS depressants may cause additive sedative effects.
Read the full Hesperidin + Zuclopenthizol interactionHigenamine Possible
What it is: Higenamine is a plant-based stimulant compound added to many weight-loss and pre-workout supplements, but there is very little human evidenc...
Theoretically, higenamine might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Higenamine + Zuclopenthizol interactionHopsHumulus Lupulus, asperge Sauvage, common Hops, +13 more Possible
What it is: Hops are most often used for sleep and mild anxiety, frequently combined with valerian, but the human evidence is limited and not very stron...
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Zuclopenthizol interactionIbogaTabernanthe Iboga, bois Sacré, eboka Possible
What it is: Iboga is a Central African shrub whose root bark contains ibogaine, a powerful hallucinogenic compound studied mainly for addiction.
Theoretically, taking iboga with serotonergic drugs might increase levels of serotonin, resulting in additive effects with serotonergic drugs.
Read the full Iboga + Zuclopenthizol interactionIpriflavone7-isopropoxyisoflavone, ipriflavona Possible
What it is: Ipriflavone is a synthetic isoflavone studied mainly for bone health and osteoporosis, but high-quality research has not shown that it relia...
Concurrent use of ipriflavone and immunosuppressant drugs might have additive effects on inhibiting immune function.
Read the full Ipriflavone + Zuclopenthizol interactionJackfruitArtocarpus Heterophyllus, arbol Del Pan, baramil, +21 more Possible
What it is: Jackfruit is a large tropical fruit that is nutritious and safe to eat as a food, offering fiber, vitamin C, potassium, and antioxidants.
Theoretically, jackfruit seeds might cause additive sedation when taken with CNS depressants.
Read the full Jackfruit + Zuclopenthizol interactionJamaican Dogwood Possible
What it is: Jamaican dogwood is a tree bark traditionally used to promote sleep and ease pain, but high-quality human studies are lacking.
Jamaican dogwood may potentiate sedative effects.
Read the full Jamaican Dogwood + Zuclopenthizol interactionJiaogulanGynostemma Pentaphyllum, adaptogen, adaptogène, +13 more Possible
What it is: Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support.
Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Read the full Jiaogulan + Zuclopenthizol interactionK2/spice Possible
What it is: K2/Spice is NOT a herbal supplement — it is plant material sprayed with man-made synthetic cannabinoid chemicals.
Theoretically, K2/spice might have an additive effect with drugs that prolong the QT interval and increase the risk of ventricular arrhythmias.
Read the full K2/spice + Zuclopenthizol interactionKefir Possible
What it is: Kefir is a fermented drink made by adding kefir grains to milk (or sugar water), creating a tangy beverage rich in probiotics.
Theoretically, kefir might increase the risk of bacterial and yeast infections in patients taking immunosuppressants.
Read the full Kefir + Zuclopenthizol interactionKhatCatha Edulis, abessinischer Tea, abyssinian Tea, +23 more Possible
What it is: Khat is a plant chewed for its amphetamine-like stimulant effects, but it carries serious risks including high blood pressure, heart problem...
Khat may affect response to antipsychotic treatment.
Read the full Khat + Zuclopenthizol interactionKhellaAmmi Visnaga, ammi Daucoides, daucus Visnaga, +13 more Possible
What it is: Khella is a Mediterranean herb whose seeds contain compounds like khellin that may relax smooth muscle in the airways and blood vessels.
Theoretically, concomitant use might result in increased photosensitivity.
Read the full Khella + Zuclopenthizol interactionKratomMitragyna Speciosa, biak-biak, cratom, +16 more Possible
What it is: Kratom is a Southeast Asian plant whose leaves act on the brain's opioid receptors and can produce both stimulant-like and opioid-like effec...
Theoretically, concomitant use might increase the risk for adverse CNS depressant effects.
Read the full Kratom + Zuclopenthizol interactionLarch ArabinogalactanLarix Decidua, larix Europaea Possible
What it is: Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support.
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactan + Zuclopenthizol interactionLemon BalmMelissa Officinalis, balm, balm Mint, +15 more Possible
What it is: Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically f...
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm + Zuclopenthizol interactionLentinanBeta-glucan Lentinan, lentinane, lentinus Edodes Polysaccharide, +4 more Possible
What it is: Lentinan is a beta-glucan polysaccharide from shiitake mushrooms that is studied mainly as an immune-modulating add-on to cancer chemotherap...
Laboratory research suggests that lentinan might increase the activity of cytochrome P450 2D6 (CYP2D6).
Read the full Lentinan + Zuclopenthizol interactionLight Therapy Possible
What it is: Light therapy uses controlled exposure to bright artificial light and is best supported for seasonal affective disorder, where it is a recog...
Light therapy may increase the risk for photosensitization.
Read the full Light Therapy + Zuclopenthizol interactionLimeCitrus Aurantifolia, adam's Apple, bara Nimbu, +11 more Possible
What it is: Lime is a common citrus fruit and a good natural source of vitamin C and plant antioxidants.
Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.
Read the full Lime + Zuclopenthizol interactionLion's Mane MushroomBearded Tooth, crinière De Lion, hedgehog Fungus, +9 more Possible
What it is: Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still li...
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Mushroom + Zuclopenthizol interactionMace Possible
What it is: Mace is the lacy red covering of the nutmeg seed and comes from the same tree as nutmeg.
Several volatile oils in mace, such as methyleugenol, isoeugenol, safrole, myristicin, 1,8-cineole, and geranyl acetate, seem to have sedative effects.
Read the full Mace + Zuclopenthizol interactionMagnoliaMagnolia Biondii, beaver Tree, bourgeon Floral De Magnolia, +13 more Possible
What it is: Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion.
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia + Zuclopenthizol interactionManganese Possible
What it is: Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most p...
Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Read the full Manganese + Zuclopenthizol interactionMaritime PinePinus Pinaster, condensed Tannins, french Marine Pine Bark Extract, +13 more Possible
What it is: Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health.
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Maritime Pine + Zuclopenthizol interactionMarsh Labrador TeaRhododendron Tomentosum, james' Tea, lède Des Marais, +13 more Possible
What it is: Marsh Labrador tea is a bog-growing shrub used in folk medicine for coughs, colds, and skin problems, but high-quality human evidence for an...
Marsh Labrador tea can potentiate effects of barbiturates and alcohol.
Read the full Marsh Labrador Tea + Zuclopenthizol interactionMelatoninN-acetyl-5-methoxytryptamine Possible
What it is: Melatonin is a hormone your body makes naturally to help control your sleep-wake cycle, and the supplement form is widely used to help with...
Theoretically, taking melatonin might increase the sedative effects of CNS depressants.
Read the full Melatonin + Zuclopenthizol interactionMethylene Blue3, 7-bis (dimethylamino)-phenazathionium Chloride, Azul De Metileno, +8 more Possible
What it is: Methylene blue is a synthetic dye that is an FDA-approved prescription medicine for a rare blood disorder called methemoglobinemia, and it i...
Combining serotonergic drugs with methylene blue can cause additive serotonergic effects, including serotonin syndrome.
Read the full Methylene Blue + Zuclopenthizol interactionMotherwortLeonurus Cardiac, agripalma, agripaume, +16 more Possible
What it is: Motherwort is a traditional herb in the mint family long used for anxiety, heart palpitations, and women's reproductive complaints, but soli...
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Zuclopenthizol interactionN,n-dmpea Possible
What it is: N,N-DMPEA (N,N-dimethylphenethylamine) is a synthetic relative of phenethylamine sometimes marketed in stimulant or pre-workout supplements.
In vitro research shows that N,N-DMPEA strongly inhibits cytochrome P450 2D6 (CYP2D6).
Read the full N,n-dmpea + Zuclopenthizol interactionNeemAzadirachta Indica, arishta, arishtha, +18 more Possible
What it is: Neem is a tree from India used for centuries in traditional medicine, especially for skin, dental, and antimicrobial purposes.
Theoretically, neem might decrease the effectiveness of immunosuppressants.
Read the full Neem + Zuclopenthizol interactionNutmegMyristica Fragrans, buah Pala, jaatipatree, +14 more Possible
What it is: Nutmeg is a popular cooking spice that has long been used in traditional medicine for digestion and other complaints, but there is little so...
Theoretically, nutmeg might increase the risk of additive sedation when taken with CNS depressants.
Read the full Nutmeg + Zuclopenthizol interactionOregon GrapeMahonia Aquifolium, barberry, berberis, +13 more Possible
What it is: Oregon grape is a shrub whose root contains berberine and related compounds.
Theoretically, Oregon grape might increase the sedative effects of CNS depressants.
Read the full Oregon Grape + Zuclopenthizol interactionPanax GinsengAsian Ginseng, asiatic Ginseng, chinese Ginseng, +12 more Possible
What it is: Panax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is m...
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Panax Ginseng + Zuclopenthizol interactionPassion FlowerPassiflora Incarnata, apricot Vine, burucuya, +18 more Possible
What it is: Passion flower is a traditional calming herb that many people use for anxiety and sleep.
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passion Flower + Zuclopenthizol interactionPhellodendronPhellodendron Amurense, amur Cork Bark, amur Cork Tree, +7 more Possible
What it is: Phellodendron is a traditional Chinese medicine bark (Huang Bai) that contains berberine and other plant compounds with antimicrobial and an...
Theoretically, phellodendron might increase the sedative effects of CNS depressants.
Read the full Phellodendron + Zuclopenthizol interactionPhenethylamine (pea)2-phenylethanamine, methylphenylethylamine, pea Possible
What it is: Phenethylamine (PEA) is a natural compound made in the body and found in foods like chocolate; supplements are marketed for mood, focus, and...
Theoretically, combining serotonergic drugs with phenethylamine might increase the risk of serotonergic adverse effects.
Read the full Phenethylamine (pea) + Zuclopenthizol interactionPhenibutBeta-phenyl-gamma-aminobutyric Acid, 4-amino-3-phenylbutyric Acid, b-(aminomethyl)-benzenepropanoic Acid, +7 more Possible
What it is: Phenibut is a synthetic, lab-made central nervous system depressant—not a natural herb—that some people use for anxiety and sleep, but it ca...
Theoretically, phenibut might increase the risk of sedation and respiratory depression when taken with CNS depressants.
Read the full Phenibut + Zuclopenthizol interactionPicrorhiza Possible
What it is: Picrorhiza (Picrorhiza kurroa) is a bitter Himalayan herb used in Ayurvedic medicine, mainly for liver and digestive complaints.
Picrorhiza seems to have immunostimulating activity.
Read the full Picrorhiza + Zuclopenthizol interactionPinellia Ternata Possible
What it is: Pinellia ternata is a tuber used in traditional Chinese medicine, most often for nausea, vomiting, and phlegmy coughs, and almost always as...
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata + Zuclopenthizol interactionPomegranatePunica Granatum, anardana, dadim, +14 more Possible
What it is: Pomegranate is a nutrient-rich fruit that is high in antioxidants and is widely enjoyed as food and juice.
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate + Zuclopenthizol interactionPoria Mushroom Possible
What it is: Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid.
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Mushroom + Zuclopenthizol interactionPropolisAcide De Cire D'abeille, baume De Propolis, bee Glue, +12 more Possible
What it is: Propolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies.
Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
Read the full Propolis + Zuclopenthizol interactionPsilocybin Possible
What it is: Psilocybin is a powerful psychedelic compound found in certain mushrooms and is being studied for hard-to-treat depression, anxiety, and add...
Theoretically, combining psilocybin with serotonergic drugs might cause additive serotonergic effects.
Read the full Psilocybin + Zuclopenthizol interactionPuravive Possible
What it is: Puravive is a branded, multi-ingredient capsule marketed mainly for weight loss by claiming to boost brown fat activity, but there is no pub...
Puravive contains Panax ginseng.
Read the full Puravive + Zuclopenthizol interactionQuercetin7-pentahydroxyflavone, bioflavonoid, bioflavonoid Complex, +9 more Possible
What it is: Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties found in many common foods and sold as a supplement.
Theoretically, concomitant use might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Quercetin + Zuclopenthizol interactionQuillaia Possible
What it is: Quillaia (soap bark tree) is a plant whose bark contains foaming compounds called saponins, and it is widely used as an emulsifier in foods...
Theoretically, concomitant use of quillaia with immunosuppressant drugs might decrease the effectiveness of these drugs.
Read the full Quillaia + Zuclopenthizol interactionRauwolscine Possible
What it is: Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout su...
Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.
Read the full Rauwolscine + Zuclopenthizol interactionRhodiolaRhodiola Rosea, arctic Root, golden Root, +12 more Possible
What it is: Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress.
Theoretically, rhodiola use might interfere with immunosuppressive therapy.
Read the full Rhodiola + Zuclopenthizol interactionRice Bran Arabinoxylan Compound Possible
What it is: Rice Bran Arabinoxylan Compound (often sold under brand names like MGN-3 or BioBran) is a processed fiber from rice bran treated with mushro...
Theoretically, rice bran arabinoxylan compound might interfere with immunosuppressants by stimulating the immune system.
Read the full Rice Bran Arabinoxylan Compound + Zuclopenthizol interactionRooibosAspalathus Linearis, green Red Bush, infusion Rooibos, +9 more Possible
What it is: Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage.
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Zuclopenthizol interactionRueRuta Graveolens, aruta, arvada, +17 more Possible
What it is: Rue is a strong-smelling herb from southern Europe with a long history in folk medicine, but there is very little reliable human research to...
Theoretically, rue might increase the risk for phototoxicity when used with photosensitizing drugs.
Read the full Rue + Zuclopenthizol interactionSaffronCrocus Sativus, autumn Crocus, azafrán, +16 more Possible
What it is: Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most r...
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron + Zuclopenthizol interactionSageSalvia Officinalis, broadleaf Sage, common Sage, +14 more Possible
What it is: Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and me...
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage + Zuclopenthizol interactionSameS-adenosyl-l-methionine, ademetionine, adomet, +8 more Possible
What it is: SAM-e is a compound your body makes naturally that is sold as a supplement, most often for depression and osteoarthritis.
Taking SAMe with serotonergic drugs might increase the risk of serotonin syndrome and other serotonergic side effects.
Read the full Same + Zuclopenthizol interactionSassafrasSassafras Albidum, ague Tree, bois De Cannelle, +7 more Possible
What it is: Sassafras is an aromatic North American tree whose root bark and oil were once popular in teas and as a flavoring, but it contains safrole,...
Theoretically, concomitant use of sassafras with drugs with sedative properties may cause additive sedative effects.
Read the full Sassafras + Zuclopenthizol interactionSceletium Possible
What it is: Sceletium (often sold as 'kanna') is a South African plant traditionally used to ease stress and lift mood.
Theoretically, concomitant use of sceletium and CNS depressants might result in additive sedative effects.
Read the full Sceletium + Zuclopenthizol interactionSchizonepeta Possible
What it is: Schizonepeta is a mint-family herb long used in traditional Chinese medicine, usually as part of combination formulas for colds, fevers, and...
Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2D6.
Read the full Schizonepeta + Zuclopenthizol interactionSelenium Possible
What it is: Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health.
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Zuclopenthizol interactionShark Cartilage Possible
What it is: Shark cartilage is a supplement made from the skeletal tissue of sharks that was heavily promoted for cancer and joint conditions, but good-...
Theoretically, shark cartilage might interfere with immunosuppressive therapy.
Read the full Shark Cartilage + Zuclopenthizol interactionShepherd's PurseCapsella Bursa-pastoris, blind Weed, bolsa Del Pastor, +14 more Possible
What it is: Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human resea...
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse + Zuclopenthizol interactionShiitake Mushroom Possible
What it is: Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people.
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Shiitake Mushroom + Zuclopenthizol interactionSkullcapScutellaria Lateriflora, american Skullcap, blue Pimpernel, +15 more Possible
What it is: American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited.
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Zuclopenthizol interactionSpearmintMentha Spicata, curled Mint, fish Mint, +16 more Possible
What it is: Spearmint is a common culinary mint that is generally safe in food and tea amounts.
Theoretically, spearmint might alter the sedative effects of CNS depressants.
Read the full Spearmint + Zuclopenthizol interactionSt. John's WortHypericum Perforatum, amber Touch-and-heal, barbe De Saint-jean, +13 more Possible
TarragonArtemisia Dracunculus, armoise Âcre, dragonne, +8 more Possible
What it is: Tarragon is a flavorful culinary herb that has been used in traditional medicine for digestion, sleep, and other complaints, but solid human...
Evidence from animal research suggests that tarragon essential oil can cause sedation and motor impairment when administered intraperitoneally at a dose of 1 mL/kg.
Read the full Tarragon + Zuclopenthizol interactionTerminaliaTerminalia Arjuna, abhaya, amandier Indien, +19 more Possible
What it is: Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness...
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia + Zuclopenthizol interactionTheacrine Possible
What it is: Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood.
Theoretically, theacrine might alter the effects of CNS depressants.
Read the full Theacrine + Zuclopenthizol interactionThuja Possible
What it is: Thuja, also called northern white cedar or arborvitae, is a tree whose leaf and oil have a long history in folk and homeopathic medicine, es...
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Zuclopenthizol interactionThunder God VineTripterygium Wilfordii, huang-t'eng Ken, lei Gong Teng, +8 more Possible
What it is: Thunder God Vine is a Chinese herb studied mainly for rheumatoid arthritis and other autoimmune conditions, with some promising but limited...
Theoretically, thunder god vine might enhance the effects of immunosuppressant drugs.
Read the full Thunder God Vine + Zuclopenthizol interactionThymus Extract Possible
What it is: Thymus extract is a glandular product made from the thymus tissue of animals, and it is promoted mainly for immune support.
Theoretically, patients taking immunosuppressants may be at an increased risk of infection from contaminated thymus extract.
Read the full Thymus Extract + Zuclopenthizol interactionTianeptine Possible
What it is: Tianeptine is a prescription antidepressant in some countries, but it is NOT approved by the FDA in the United States and is illegally sold...
Tianeptine has sedative effects; high doses may have additive effects with other CNS depressants.
Read the full Tianeptine + Zuclopenthizol interactionTinospora Cordifolia Possible
What it is: Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat...
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Zuclopenthizol interactionTree Turmeric Possible
What it is: Tree turmeric (Berberis aristata) is a shrub used in traditional Indian (Ayurvedic) medicine, valued mainly for its berberine content.
Theoretically, use of tree turmeric along with CNS depressants might increase the risk of additive therapeutic and adverse effects.
Read the full Tree Turmeric + Zuclopenthizol interactionTrichopus Zeylanicus Possible
What it is: Trichopus zeylanicus is a tropical herb traditionally used as a tonic to boost energy and resist stress, but human evidence is very limited...
Theoretically, Trichopus zeylanicus might reduce the effects of immunosuppressants.
Read the full Trichopus Zeylanicus + Zuclopenthizol interactionUmckaloaboAfrican Geranium Possible
What it is: Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respirat...
Theoretically, Pelargonium sidoides might decrease the effectiveness of immunosuppressant therapy.
Read the full Umckaloabo + Zuclopenthizol interactionValerianValeriana Officinalis, all-heal, amantilla, +10 more Possible
What it is: Valerian is an herb whose root is widely used as a natural sleep aid and for calming nerves.
Valerian can have additive sedative effects when used concomitantly with CNS depressant drugs.
Read the full Valerian + Zuclopenthizol interactionVitex Agnus-castusAgneau Du Moine, agneau-chaste, agni Casti, +16 more Possible
What it is: Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some...
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Read the full Vitex Agnus-castus + Zuclopenthizol interactionWhite Pepper Possible
What it is: White pepper comes from the same plant as black pepper and is mostly used as a kitchen spice.
In vitro evidence suggests that some constituents of white pepper inhibit cytochrome P450 2D6 (CYP2D6).
Read the full White Pepper + Zuclopenthizol interactionWild LettuceLactuca Virosa, acrid Lettuce, allubbyne, +13 more Possible
What it is: Wild lettuce is a traditional herb used mainly for sleep, anxiety, and pain, but solid human research supporting these uses is very limited.
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce + Zuclopenthizol interactionYin ChenArmoise à Balais, armoise Capillaire, artemisia Officinalis, +11 more Possible
What it is: Yin Chen is a traditional Chinese medicine herb used mainly for liver and gallbladder complaints and jaundice.
Theoretically, yin chen might enhance the therapeutic and adverse effects of other CNS depressants.
Read the full Yin Chen + Zuclopenthizol interactionYohimbePausinystalia Yohimbe, 11-hydroxy Yohimbine, coryanthe Yohimbe, +7 more Possible
What it is: Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac.
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Yohimbe + Zuclopenthizol interactionZizyphusZiziphus Jujuba, anèbe, annab, +20 more Possible
What it is: Zizyphus (jujube) is an edible fruit and traditional remedy used mainly for sleep, anxiety, and digestion.
Theoretically, zizyphus might cause additive sedative effects when taken with CNS depressants.
Read the full Zizyphus + Zuclopenthizol interactionLavenderLavandula Angustifolia, alhucema, common Lavender, +14 more Unlikely
What it is: Lavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for...
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Lavender + Zuclopenthizol interaction1,3-dmba Possible
What it is: 1,3-DMBA is a synthetic stimulant chemically similar to the banned stimulant DMAA, and it is not a proven or safe dietary ingredient.
Theoretically, 1,3-DMBA might modestly increase the levels of CYP2D6 substrates.
Read the full 1,3-dmba + Zuclopenthizol interactionCalea Zacatechichi Possible
What it is: Calea zacatechichi, often called 'dream herb,' is a Mexican plant traditionally used to encourage vivid dreams and to treat digestive compla...
Theoretically, Calea zacatechichi might increase the sedative effects of CNS depressants.
Read the full Calea Zacatechichi + Zuclopenthizol interactionCeleryApium Graveolens, ache Des Marais, ajamoda, +13 more Possible
What it is: Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint d...
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Zuclopenthizol interactionFucus VesiculosusBlack Tang, bladder Fucus, bladder Wrack, +14 more Possible
What it is: Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin.
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Fucus Vesiculosus + Zuclopenthizol interactionHibiscus SabdariffaHibiscus Sabdariffa, agua De Jamaica, ambashthaki, +16 more Possible
What it is: Hibiscus sabdariffa is a tart, cranberry-flavored plant most often consumed as a tea, and its best-studied use is for mildly lowering blood...
Theoretically, Hibiscus sabdariffa extract might reduce the metabolism of CYP2D6 substrates.
Read the full Hibiscus Sabdariffa + Zuclopenthizol interactionHordenineAnhalinine Possible
What it is: Hordenine is a natural alkaloid found in barley and some cacti that is marketed as a stimulant for energy, focus, and fat loss, but solid hu...
Hordenine weakly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.
Read the full Hordenine + Zuclopenthizol interactionLychee Possible
What it is: Lychee is a sweet tropical fruit that is nutritious and a source of vitamin C and antioxidant plant compounds.
Theoretically, lychee might reduce the effectiveness of immunosuppressant drugs.
Read the full Lychee + Zuclopenthizol interactionBaikal SkullcapScutellaria Baicalensis, baikal Scullcap, baikal Skullcap Root, +16 more Unlikely
What it is: Baikal skullcap is a traditional Chinese herb (Huang Qin) used for inflammation, allergies, and infections, with active compounds like baica...
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Baikal Skullcap + Zuclopenthizol interactionCalendulaCalendula Officinalis, caléndula, calendule, +13 more Unlikely
What it is: Calendula is a flowering plant whose petals are used mainly in skin creams, oils, and ointments to soothe minor irritation and support wound...
Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.
Read the full Calendula + Zuclopenthizol interactionGamma-aminobutyric Acid (gaba)Acide Bêta-phényl-gamma-amino-butyrique, acide Gamma-aminobutyrique, Ácido Gama-aminobutríco, +3 more Unlikely
What it is: GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety,...
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid (gaba) + Zuclopenthizol interactionHumann Superbeets Heart Chews Unlikely
What it is: SuperBeets Heart Chews are a beetroot- and grape-seed-based supplement marketed to support healthy blood flow, blood pressure, and nitric ox...
Each serving of HumanN SuperBeets includes 150mg of grape seed extract (2 chews).
Read the full Humann Superbeets Heart Chews + Zuclopenthizol interactionTheanine Unlikely
What it is: Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without...
Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Theanine + Zuclopenthizol interactionCan You Take It With Zuclopenthizol?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Terminalia with Zuclopenthizol?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Full Terminalia + Zuclopenthizol answerCan you take Cordyceps with Zuclopenthizol?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Full Cordyceps + Zuclopenthizol answerCan you take Jiaogulan with Zuclopenthizol?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Full Jiaogulan + Zuclopenthizol answerCan you take Cannabichromene (cbc) with Zuclopenthizol?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Using cannabichromene with drugs that have sedative properties may cause additive therapeutic and adverse effects.
Full Cannabichromene (cbc) + Zuclopenthizol answerCan you take Fermented Wheat Germ Extract with Zuclopenthizol?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of fermented wheat germ extract with serotonergic medications may increase the risk of serotonergic adverse e...
Full Fermented Wheat Germ Extract + Zuclopenthizol answerCan you take Celery with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Full Celery + Zuclopenthizol answerCan you take Fucus Vesiculosus with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Full Fucus Vesiculosus + Zuclopenthizol answerCan you take Hibiscus Sabdariffa with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Hibiscus sabdariffa extract might reduce the metabolism of CYP2D6 substrates.
Full Hibiscus Sabdariffa + Zuclopenthizol answerCan you take Hordenine with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Hordenine weakly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.
Full Hordenine + Zuclopenthizol answerCan you take Lychee with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, lychee might reduce the effectiveness of immunosuppressant drugs.
Full Lychee + Zuclopenthizol answerCan you take Baikal Skullcap with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative propert...
Full Baikal Skullcap + Zuclopenthizol answerCan you take Calendula with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.
Full Calendula + Zuclopenthizol answerCan you take Gamma-aminobutyric Acid (gaba) with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Full Gamma-aminobutyric Acid (gaba) + Zuclopenthizol answerCan you take Humann Superbeets Heart Chews with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Each serving of HumanN SuperBeets includes 150mg of grape seed extract (2 chews).
Full Humann Superbeets Heart Chews + Zuclopenthizol answerCan you take Theanine with Zuclopenthizol?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants.
Full Theanine + Zuclopenthizol answerCan you take Beer with Zuclopenthizol?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase sedative and other adverse effects.
Full Beer + Zuclopenthizol answerCan you take Wine with Zuclopenthizol?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase sedative and other adverse effects.
Full Wine + Zuclopenthizol answerCan you take 1,4-butanediol with Zuclopenthizol?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use of 1,4-butanediol with CNS depressants may potentiate respiratory and CNS depression.
Full 1,4-butanediol + Zuclopenthizol answerCan you take Arsenic with Zuclopenthizol?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Arsenic trioxide can prolong the QT interval.
Full Arsenic + Zuclopenthizol answerCan you take Cesium with Zuclopenthizol?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, taking cesium concomitantly with other drugs that prolong the QT interval may increase the risk of ventricular arrhythmias an...
Full Cesium + Zuclopenthizol answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Zuclopenthizol is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Zuclopenthizol, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Zuclopenthizol sits in 9 interaction categories. Open any one to see what the group means:
Cns Depressants 78 ingredients
Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.
78 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
60 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Immunosuppressants 53 ingredients
Medications that damp down the immune system. Supplements that stimulate immunity can work against them.
53 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Photosensitizing Drugs 20 ingredients
Medications that make skin more sun-sensitive. Supplements with the same property can compound it.
20 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Serotonergic Drugs 20 ingredients
Medications that raise serotonin activity. Combining them with serotonin-active supplements can, in rare cases, push serotonin too high.
20 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Qt Interval-Prolonging Drugs 13 ingredients
Medications that can affect the heart's electrical rhythm (the QT interval). Supplements with similar effects can add to that risk.
13 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Antipsychotic Drugs 8 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
8 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Seizure Threshold Lowering Drugs 6 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
6 of the supplement ingredients on this page reach Zuclopenthizol through this category.
Serotonergic Drugs 1 ingredient
Medications that raise serotonin activity. Combining them with serotonin-active supplements can, in rare cases, push serotonin too high.
1 of the supplement ingredient on this page reaches Zuclopenthizol through this category.
Take a Supplement Product? Check the Whole Bottle Against Zuclopenthizol
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Zuclopenthizol.
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Zuclopenthizol & Supplements: Common Questions
What supplements interact with Zuclopenthizol?
Which Zuclopenthizol supplement interactions are the most serious?
Can I take vitamins or supplements while on Zuclopenthizol?
Do brands like Clopixol have the same supplement interactions as Zuclopenthizol?
Where do these interaction ratings come from?
What about Zuclopenthizol and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 24, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.