Medication interaction hub

What Supplements Interact with Fosinopril?

Fosinopril brand name: Monopril. Every interaction below applies to the brands too.

166 Interactions 6 Major 136 Moderate 24 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Fosinopril? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Fosinopril against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

I would read the supplement list for fosinopril (Monopril), a blood pressure medicine, with genuine care, because a handful of these combinations can do real harm. Most of what interacts touches blood pressure itself, either adding to fosinopril's lowering effect or working against it, tyramine being a well-documented example of the latter. A smaller set can raise potassium, which fosinopril already tends to do, and American hellebore stands out for potent heart effects even at small doses.

Activated charcoal deserves a separate mention because it can soak up the medicine in the gut and blunt its absorption, so space the two well apart. A few others can strain the kidneys, which matters since ACE inhibitors like this one depend on healthy kidney function. Six of the 166 ingredients here carry a major rating, alongside 136 moderates and 24 minors, and those six are where I would start reading.

— , Clinical Pharmacist · July 18, 2026

Major 6 Moderate 136 Minor 24 No known interaction 1,286

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Fosinopril: Top Interactions at a Glance

The Fosinopril supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 166 interacting ingredients — plus 1,286 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Fosinopril Combinations Today

The Fosinopril + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Unlikely Capsicum + Fosinoprili

Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.

Read the full interaction Minor Likelihood Possible Humann Superbeets Heart Chews + Fosinoprili

Each serving of HumanN SuperBeets includes 500mg of beetroot powder (2 chews).

Read the full interaction Moderate Likelihood Probable L-arginine + Fosinoprili

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.

Read the full interaction Moderate Likelihood Possible Fermented Milk + Fosinoprili

Theoretically, fermented milk might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full interaction Moderate Likelihood Possible Tree Turmeric + Fosinoprili

Theoretically, taking tree turmeric along with antihypertensive drugs might have additive effects and increase the risk of hypotension.

Read the full interaction Major Likelihood Likely American Hellebore + Fosinoprili

American hellebore can have potent cardiovascular effects due to the toxic steroid ester alkaloids it contains.

Read the full interaction
The complete list

Every Supplement Checked Against Fosinopril

All 1,452 ingredients in our database, ranked by severity — 166 with a Fosinopril interaction on file and 1,286 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Fosinopril?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Capsicum with Fosinopril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.

Full Capsicum + Fosinopril answer

Can you take Humann Superbeets Heart Chews with Fosinopril?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Each serving of HumanN SuperBeets includes 500mg of beetroot powder (2 chews).

Full Humann Superbeets Heart Chews + Fosinopril answer

Can you take L-arginine with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.

Full L-arginine + Fosinopril answer

Can you take Fermented Milk with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fermented milk might increase the risk of hypotension when taken with antihypertensive drugs.

Full Fermented Milk + Fosinopril answer

Can you take Tree Turmeric with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking tree turmeric along with antihypertensive drugs might have additive effects and increase the risk of hypotension.

Full Tree Turmeric + Fosinopril answer

Can you take Khat with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Human research shows that khat and its constituent, cathinone, can increase blood pressure.

Full Khat + Fosinopril answer

Can you take Khella with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Khella + Fosinopril answer

Can you take Kiwi with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research suggests that consuming kiwi reduces systolic and diastolic blood pressure in hypertensive individuals.

Full Kiwi + Fosinopril answer

Can you take Korean Pine with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research shows that Korean pine nut oil reduces blood pressure in spontaneously hypertensive rats.

Full Korean Pine + Fosinopril answer

Can you take L-citrulline with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotensio...

Full L-citrulline + Fosinopril answer

Can you take Laminaria with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, laminaria might increase the risk of hyperkalemia when taken with ACEIs.

Full Laminaria + Fosinopril answer

Can you take Licorice with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, licorice might reduce the effects of antihypertensive drugs.

Full Licorice + Fosinopril answer

Can you take Light Therapy with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Light therapy may increase the risk for photosensitization.

Full Light Therapy + Fosinopril answer

Can you take Lime with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.

Full Lime + Fosinopril answer

Can you take Lithium with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lithium supplements with ACEIs might increase levels and adverse effects of lithium.

Full Lithium + Fosinopril answer

Can you take Maitake Mushroom with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.

Full Maitake Mushroom + Fosinopril answer

Can you take Malic Acid with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, malic acid might increase the risk of hypotension when taken with antihypertensive drugs.

Full Malic Acid + Fosinopril answer

Can you take Melatonin with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking melatonin with antihypertensive drugs might increase the risk of hypotension or hypertension.

Full Melatonin + Fosinopril answer

Can you take Mountain Ash with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent.

Full Mountain Ash + Fosinopril answer

Can you take N-acetyl Cysteine (nac) with Fosinopril?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.

Full N-acetyl Cysteine (nac) + Fosinopril answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Fosinopril is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Fosinopril, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Fosinopril sits in 5 interaction categories. Open any one to see what the group means:

Antihypertensive Drugs 119 ingredients

Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.

119 of the supplement ingredients on this page reach Fosinopril through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Fosinopril through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Fosinopril through this category.

Ace Inhibitors (Aceis) 12 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

12 of the supplement ingredients on this page reach Fosinopril through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Fosinopril through this category.

About Fosinopril

Fosinopril is an ACE inhibitor used to treat high blood pressure and heart failure.

Generic name: Fosinopril  ·  Brand name: Monopril.

See the full Fosinopril drug information

Related: does Fosinopril deplete any nutrients?

Fosinopril has 1 reported nutrient association in the research literature — see the Fosinopril nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Fosinopril

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Fosinopril.

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Pharmacist Counseling Corner

Fosinopril & Supplements: Common Questions

What supplements interact with Fosinopril?
Our database currently documents 166 ingredients with a known Fosinopril interaction (6 major, 136 moderate, 24 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 166. The highest-ranked right now: American Hellebore, Siberian Cocklebur, Tyramine.
Which Fosinopril supplement interactions are the most serious?
The 6 major-rated combinations — led by American Hellebore, Siberian Cocklebur, Tyramine, Activated Charcoal and American Mistletoe — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Fosinopril?
Plenty of supplements coexist fine with Fosinopril; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Monopril have the same supplement interactions as Fosinopril?
Yes — Monopril all contain Fosinopril, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Fosinopril deplete any vitamins or nutrients?
It might — Fosinopril has 1 reported nutrient-depletion association in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Fosinopril nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Fosinopril and my other medications?
This page covers Fosinopril against supplements and herbal ingredients. Checking Fosinopril against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Fosinopril drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.