Clopidogrel

Name: Clopidogrel Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

359 interactions 1 explained in plain English 501 cited references

Also sold as: Plavix Plavix®

About Clopidogrel

Clopidogrel is an antiplatelet medication used to prevent heart attacks and strokes in people with heart disease or poor circulation. Read the full Clopidogrel drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Injection Abrocitinib Defibrotide Darunavir Nalbuphine Injection Methotrexate Injection

3 Contraindicated 239 Major 115 Moderate 2 Minor

All (359) Contraindicated (3) Major (239) Moderate (115) Minor (2)

Contraindicated

Clopidogrel Abrocitinib Cibinqo Increased risk of bleeding Details Clopidogrel Defibrotide Increased risk of bleeding Details Clopidogrel Defibrotide Injection Defitelio Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.