Herb & supplement monograph

Burdock Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Burdock interacts with medications. The heart of this page is the interaction list — every drug Burdock is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Burdock is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Burdock Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Burdock drug interaction appears low for most people. None of the listed interactions are rated major, and the single concern behind them all rests on lab research rather than anything reported in people.

Interactions deserving the most attention

The one area worth attention is anticoagulant and antiplatelet medications, often called blood thinners. Lab studies suggest compounds in burdock might slow platelet activity, which in theory could add to the effect of these drugs and raise bleeding risk. Because bleeding is a serious outcome and these medicines work within a narrow margin, we think this combination deserves the most care, even though the effect has not been shown in humans.

What the rest of the list means

The long list of interacting medications can look worrying, but it reflects one theoretical concern applied across every blood-thinning drug rather than many separate problems. The evidence comes from laboratory research on platelets, and no bleeding interaction with burdock has actually been reported in people, so most of these predicted effects remain unproven.

Check your medications against Burdock

Based on HelloPharmacist’s Burdock interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Burdock

122 medications have a known interaction with Burdock, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AbciximabReoPro
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Abciximab interaction
AbrocitinibCibinqo
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Abrocitinib interaction Abrocitinib drug page: uses, dosage & side effects
AcenocoumarolSintrom
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Acenocoumarol interaction
Acetaminophen, AspirinGemnisyn
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Acetaminophen, Aspirin interaction
Acetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Acetaminophen, Aspirin, Caffeine interaction
Acetaminophen, IbuprofenCombogesic
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Acetaminophen, Ibuprofen interaction
Acetylsalicylic AcidEntrophen
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Acetylsalicylic Acid interaction Acetylsalicylic Acid drug page: uses, dosage & side effects
Alteplase, TpaActilyse, Activase
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Alteplase, Tpa interaction
Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interaction
Aluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction Aluminum Hydroxide, Aspirin, Magnesium Hydroxide drug page: uses, dosage & side effects
Anacaulase-bcdbNexoBrid
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Anacaulase-bcdb interaction
AnagrelideAgrylin
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Anagrelide interaction Anagrelide drug page: uses, dosage & side effects
AnisindioneMiradon
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Anisindione interaction
Antithrombin IiiThrombate III
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Antithrombin Iii interaction
ApixabanEliquis
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Apixaban interaction Apixaban drug page: uses, dosage & side effects
ArgatrobanArgatroban
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Argatroban interaction
AspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin interaction Aspirin drug page: uses, dosage & side effects
Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interaction
Aspirin, ButalbitalAxotal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Butalbital interaction
Aspirin, Butalbital, CaffeineFiorinal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Butalbital, Caffeine interaction Aspirin, Butalbital, Caffeine drug page: uses, dosage & side effects
Aspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Butalbital, Caffeine, Codeine Phosphate interaction
Aspirin, Butalbital, Caffeine, PhenacetinMarnal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Butalbital, Caffeine, Phenacetin interaction
Aspirin, CaffeineAnacin
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine interaction
Aspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Codeine Phosphate interaction
Aspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction
Aspirin, Caffeine, Dover's PwdAcedoval, Dovacet
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Dover's Pwd interaction
Aspirin, Caffeine, HydrocodoneDamason-P
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Hydrocodone interaction
Aspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interaction Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin drug page: uses, dosage & side effects
Aspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Orphenadrine interaction
Aspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full Burdock + Aspirin, Caffeine, Phenacetin, Propoxyphene interaction
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Burdock combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Burdock affects

Every type of medication (drug category) Burdock is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 1 drug category Burdock interacts with
Anticoagulant/antiplatelet Drugs
Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Monograph

Burdock: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is widely eaten as a vegetable and is generally considered low-risk for short-term use in healthy adults, but it should be avoided during pregnancy and breastfeeding and by people allergic to ragweed or daisy-family plants.

Burdock
Scientific name
Arctium lappa
Family
Asteraceae
Part used
Root, leaves, and seeds (fruit)
Common forms
Tea, dried root, capsules, tinctures, liquid extracts, and fresh root used as food
People commonly use it for
  • Skin conditions like acne and eczema
  • Digestive support
  • Diuretic ('detox') and blood purifier
  • Sore throat and cold symptoms
  • Antioxidant support

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Likely safe as a food and for short-term use in healthy adults, but human safety data are limited.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Burdock (Arctium lappa) is a plant in the daisy family that is native to Europe and Asia and now grows in many parts of the world. It has large leaves and long, slender roots, and is easy to spot by its round, prickly burrs that cling to clothing and animal fur.

The root is eaten as a vegetable in some cultures, especially in Japan, where it is known as gobo. In traditional medicine, the root, leaves, and seeds have all been used to make teas, tinctures, and capsules. People have long used burdock as a so-called 'blood purifier' and for skin and digestive complaints.

How it works

Burdock contains several plant compounds that may explain its traditional uses. These include inulin (a type of fiber), antioxidant compounds such as lignans (like arctigenin and arctiin), phenolic acids, and other plant chemicals.

In laboratory and animal studies, these compounds have shown antioxidant, anti-inflammatory, and antibacterial activity. The inulin fiber in the root may act as a prebiotic, feeding helpful gut bacteria.

It is important to know that most of this research has not been confirmed in large human studies. Effects seen in a test tube or in animals do not always happen in people.

Effectiveness

Does Burdock work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 14 uses evaluated
14 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Burdock, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 14 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Acne
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using topical burdock for acne, there is insufficient reliable information about the clinical effects of burdock for this purpose.

Insufficient Reliable Evidence To Rate Aging skin
Rating & evidence shown verbatim from Natural Medicines

It is unclear if topical burdock is beneficial for reducing wrinkles.

Insufficient Reliable Evidence To Rate Atopic dermatitis (eczema)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using topical burdock for eczema, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Breast cancer
Rating & evidence shown verbatim from Natural Medicines

Oral burdock root has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Common cold
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral burdock for symptoms of the common cold, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral burdock for diabetes, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Diverticulitis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral burdock is beneficial in patients with diverticulitis.

Insufficient Reliable Evidence To Rate Dry skin
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using topical burdock for dry skin, there is insufficient reliable information about the clinical effects of burdock for this purpose.

Insufficient Reliable Evidence To Rate Gout
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral burdock for gout, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Hepatitis
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral burdock for hepatitis, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Metabolic syndrome
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral burdock is beneficial in patients with metabolic syndrome.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral burdock for obesity, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Urinary tract infections (UTIs)
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral burdock for UTI, there is insufficient reliable information about the clinical effects of burdock for this condition.

Insufficient Reliable Evidence To Rate Vaginitis
Rating & evidence shown verbatim from Natural Medicines

Topical burdock has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Burdock root is widely eaten as food and is generally considered low-risk for short-term use in healthy adults. Still, human safety studies are limited.

People who are allergic to ragweed, chrysanthemums, marigolds, daisies, or other Asteraceae plants may also react to burdock and should be cautious. There have also been rare reports of poisoning from burdock teas that were contaminated with belladonna (a toxic plant), so buy from reputable sources.

Because burdock may act as a diuretic, people who are dehydrated or taking medications that affect fluid balance should use caution. Pregnant people should avoid medicinal amounts, since some sources suggest it could affect the uterus and safety data are lacking. Breastfeeding parents should also avoid it due to insufficient information. Always check with your pharmacist or doctor before starting any new supplement.

Side effects

When used in food amounts or for short periods, burdock is usually well tolerated. Possible side effects include allergic reactions (skin rash, itching, or, rarely, more serious reactions), especially in people sensitive to daisy-family plants.

Because it can increase urine output, it may contribute to dehydration if you don't drink enough fluids. Skin contact with the plant can cause irritation in some people. Serious problems are rare but have occurred when products were contaminated with toxic plants — another reason to choose trusted brands.

Burdock: Reported Adverse Effects

Documented safety reports on Burdock from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, burdock is well tolerated when consumed as a food. Although a thorough evaluation of safety outcomes is lacking, there has been long-standing historical use of burdock with few noted adverse effects.

Serious Adverse Effects (Rare):

All ROAs: Allergic reactions, including contact dermatitis and anaphylaxis.

Reports by condition
Cirrhosis Hepatic

A case of idiosyncratic drug-induced liver disease (DILI) is reported in a 36-year-old female who presented with abdominal pain after 1 month of taking an herbal liver detox tea containing burdock and other ingredients. Remarkable laboratory values included elevated liver enzymes, alkaline phosphatase, and total bilirubin. The patient received a loading dose of N-acetylcysteine and was hospitalized for 12 days. However, it is unclear if the adverse effect was due to burdock, other ingredients, or the combination.

  1. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617.
Dermatitis Dermatologic

Contact dermatitis has been reported secondary to burdock, especially after prolonged use of the root oil. There are cases of allergic dermatitis secondary to using burdock plasters. Two males and a 14 year-old female developed erythematous and vesicular, pruritic, and exudative reactions in areas corresponding to the application of burdock root plasters. Reactions occurred up to 7 days after initial use. Patch testing was positive for burdock sensitivity in all three patients and was nonreactive in matched controls.

  1. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254.
  2. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
Dry mouth Neurologic/CNS

Anticholinergic reactions including dry mouth, dizziness, blurred vision, weakness, dilated pupils, inability to urinate, and bradycardia have been reported following the consumption of burdock products. However, these anticholinergic reactions are believed result from contamination of burdock with belladonna alkaloids. Burdock itself does not contain atropine or other constituents that would be responsible for these reactions.

  1. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4.
  2. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288.
  3. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  4. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157.
  5. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p>
Fatigue Hematologic

In one case report, a 38-year-old female developed immune-mediated thrombocytopenia after consuming a "cleansing" tea containing unknown amounts of burdock and yellow dock. The patient presented with bruising, mild weakness, and fatigue, which started 2-3 days after consuming the tea, and was found to have a platelet count of 5,000 per mcL. Symptoms resolved after platelet transfusion and treatment with oral dexamethasone. It is unclear if these effects were caused by burdock, yellow dock, the combination, or other contributing factors.

  1. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247.
Hypotension Immunologic

There is one case of anaphylactic shock secondary to eating boiled burdock. One hour after eating boiled burdock the patient presented with redness over the entire body and dyspnea. He was found to have low blood pressure and was treated with subcutaneous epinephrine 1 mg and intravenous lactated ringer's solution containing hydrocortisone 100 mg and dexamethasone 8 mg. The cause of anaphylactic shock was attributed to allergenicity to burdock based on positive skin prick test results. Previously, the patient had experienced urticaria after eating boiled burdock.

  1. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no well-established standard dose of burdock for any medical condition. Amounts vary widely depending on whether you use the fresh root, dried root tea, a tincture, or a capsule.

The best approach is to follow the directions on the product label and start with the lowest suggested amount. Because product strength and quality can vary a lot, talk with your pharmacist or doctor before using burdock, especially if you take other medicines or have a health condition.

Pregnancy & Breastfeeding

Burdock & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Burdock & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 11 references that drive our Burdock monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Burdock

436 brands in our database make a supplement containing Burdock.

Product directory

Supplement products with Burdock

2,016 products in our database contain Burdock. Open any to see its full ingredient list and every drug interaction we check.

Bio Slim by BioLife Energy Systems Liquid 1 oz. View ingredients & interactions Bio-Detox Packs by Biotics Research Corporation Unknown 30 Pack(s) View ingredients & interactions Bio.Clear Endotox LV by Invivo Capsule 90 Capsule(s) View ingredients & interactions Biodynamic LiverLove Extract by Oregon's Wild Harvest Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Biodynamic LiverLove Extract by Oregon's Wild Harvest Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Biodynamic LiverLove Extract by Oregon's Wild Harvest Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Bitter Roots by Herbalist & Alchemist Liquid 2 fl. Oz. · 60 mL View ingredients & interactions Bitters Extra by Vitanica Capsule 30 Vegetarian Capsule(s) View ingredients & interactions Bitters Extra by Vitanica Capsule 90 Vegetarian Capsule(s) View ingredients & interactions Bladder & Estrogen by Remedys Nutrition Capsule 60 Vcap(s) View ingredients & interactions BLDB Tonic by Systemic Formulas Bio Challenge Capsule 60 Capsule(s) View ingredients & interactions Blood & Body Cleanse by Signature Supplements Capsule 100 Capsule(s) View ingredients & interactions Blood Cleanse by Health Plus Capsule 90 Capsule(s) View ingredients & interactions Blood Cleanse by Banyan Botanicals Tablet Or Pill 90 Tablet(s) View ingredients & interactions Blood Cleanse by Banyan Botanicals Tablet Or Pill 90 Tablet(s) View ingredients & interactions Blood Detox by Crystal Star Capsule 90 Vegetarian Capsule(s) View ingredients & interactions Blood Nourish-R by LifeSeasons Therapeutics Capsule 60 Veg Capsule(s) View ingredients & interactions Blood Stream Formula by Christopher's Original Formulas Capsule 100 Vegetarian Cap(s) View ingredients & interactions Blood Stream Formula by Christopher's Original Formulas Liquid 2 fl. Oz. · 59 mL View ingredients & interactions Blood Stream Formula Syrup by Christopher's Original Formulas Liquid 4 fl. Oz. · 118 mL View ingredients & interactions Blood Support Papaya Leaf Formula by Herbal Goodness Capsule 30 Capsule(s) View ingredients & interactions Blood Support Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Blood Support Tincture by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega Softgel Capsule 30 Pack(s) View ingredients & interactions
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Burdock: Common Questions

What is Burdock used for, and does it work?
People use Burdock for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Burdock interact with prescription medications?
Yes. We list 122 medications with a known interaction with Burdock. Use the checker above to see how Burdock interacts with a specific drug.
How are Burdock interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Burdock with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Burdock interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Burdock used for?
It is traditionally used for skin problems like acne and eczema, for digestion, as a diuretic or 'blood purifier,' and for sore throats and colds. However, strong human evidence is lacking for most of these uses.
Is Burdock safe to take?
Burdock root is commonly eaten as a vegetable and is generally low-risk for short-term use in healthy adults. People allergic to ragweed or daisy-family plants should be cautious, and you should buy from reputable sources to avoid contamination.
Can I take Burdock while pregnant or breastfeeding?
It is best to avoid medicinal amounts of Burdock during pregnancy and breastfeeding, because there isn't enough safety information and some sources suggest it could affect the uterus.
Is Burdock the same as the vegetable gobo?
Yes. The Burdock root is eaten as a vegetable in some cuisines, especially in Japan, where it is called gobo. Eating it as food is different from taking concentrated supplements or strong teas.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Products that contain Burdock

A rotating sample of real supplements in our database that list Burdock — open any to see its full ingredients and every drug interaction we check.

See all 2,016 products with Burdock →
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