Drug & supplement interaction

Yohimbe + Salbutamol Sulfate

Salbutamol Sulfate brand names: Ventolin, Salvent, Salmol, Airomir, Asmasal Clickhaler, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Yohimbe and Salbutamol Sulfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Yohimbe and Salbutamol Sulfate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Salbutamol Sulfate and Yohimbe in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yohimbe safety at a glance

Yohimbe overall Use caution Yohimbe can cause serious heart and blood pressure effects and supplement potency is unpredictable.
Pregnancy Possibly Unsafe When used orally. Yohimbe might have uterine relaxant effects and also cause fetal toxicity. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. Yohimbe might have uterine relaxant effects and also cause fetal toxicity. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Salbutamol Sulfate and Yohimbe? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Salbutamol Sulfate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Salbutamol Sulfate is filed under 2 classifications — beta-adrenergic agonists, oral drugs. Yohimbe has documented interactions with 13 drug classes — the most serious being monoamine oxidase inhibitors (maois) (major), antihypertensive drugs (moderate) and clonidine (catapres) (moderate) — and none of Salbutamol Sulfate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Yohimbe Does Interact With Other Medications

Yohimbe has 9 major, 680 moderate, 436 minor known drug interactions in our database — Salbutamol Sulfate isn’t one of them. If you take anything else, check it against the full list below.

Major 9 Moderate 680 Minor 436 No known interaction 1,705 (incl. Salbutamol Sulfate)
Taking anything else?

Check Another of Your Medications Against Yohimbe

Covers the 2,830 medications we’ve checked against Yohimbe. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Yohimbe and Salbutamol Sulfate May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on Additional detail

    Yohimbe

    “Orally, yohimbine, a constituent of yohimbe, may cause bronchospasm, tachypnea, cough, and rhinorrhea. A case of sinusitis characterized by pain and discomfort above both eyes has been reported for a 59-year-old male taking yohimbine 5.4 mg three times daily to treat erectile dysfunction. Symptoms resolved within 24 hours of discontinuing yohimbine.”

    Yohimbe · Natural Medicines adverse-effect record, reported in cough.

    5 sources cited
    1. 17465. Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
    2. 86825. Landis, E. and Shore, E. Yohimbine-induced bronchospasm. Chest 1989;96(6):1424. PubMed
    3. 86850. Charney, D. S., Heninger, G. R., and Sternberg, D. E. Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine. Life Sci 6-7-1982;30(23):2033-2041.
    4. 94112. Wylie KR. Yohimbine and sinusitis. Br J Psychiatry. 1996;169(3):384-5. PubMed
    5. 1118. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.

    Salbutamol Sulfate

    Listed in the ADVERSE REACTIONS section of the FDA label for Salbutamol Sulfate. Read the label on DailyMed ›

  • An allergic reaction Worth acting on Additional detail

    Yohimbe

    “There is one report of a hypersensitivity reaction including fever; chills; malaise; itchy, scaly skin; progressive renal failure; and lupus-like syndrome associated with ingestion of a one-day dose of yohimbine, a constituent of yohimbe.”

    Yohimbe · Natural Medicines adverse-effect record, reported in kidney failure.

    1 source cited
    1. 6169. Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed

    Salbutamol Sulfate

    Listed in the ADVERSE REACTIONS section of the FDA label for Salbutamol Sulfate. Read the label on DailyMed ›

  • Cough Additional detail

    Yohimbe

    Recorded for Yohimbe in the same Natural Medicines adverse-effect record shown under Wheezing above.

    Salbutamol Sulfate

    Listed in the ADVERSE REACTIONS section of the FDA label for Salbutamol Sulfate. Read the label on DailyMed ›

Reported for Yohimbe but not commonly for Salbutamol Sulfate: stomach upset, fainting, a heart attack and erection problems.

Effects for Salbutamol Sulfate come from the ADVERSE REACTIONS section of its FDA label; effects for Yohimbe come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Yohimbe in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. Yohimbe might have uterine relaxant effects and also cause fetal toxicity.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Yohimbe or Salbutamol Sulfate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Yohimbe or Salbutamol Sulfate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Salbutamol Sulfate

This page covers Yohimbe only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Salbutamol Sulfate page lists 32 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Black Tea (moderate), Caffeine (moderate), Cocoa (moderate) and Coffee (moderate).

By severity: 1 major · 22 moderate · 9 minor.

From our pharmacist’s overview on the Salbutamol Sulfate page

“People who rely on salbutamol (Ventolin) to open their airways during asthma or COPD flares should give this list real attention, starting with its one major-rated interaction, activated charcoal. Charcoal, sold in detox and gut-cleanse products, can soak up many medicines and blunt their effect.”

Reviewed by 2 · Jul 18, 2026

Open the Salbutamol Sulfate interaction page

One more smart check

Taking Yohimbe as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,054 real supplement products containing Yohimbe, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yohimbe. Even though Yohimbe itself has no known interaction with Salbutamol Sulfate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Yohimbe and Salbutamol Sulfate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yohimbe
Top 25%

#173 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Salbutamol Sulfate
Top 5%

#66 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yohimbe reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Yohimbe and Salbutamol Sulfate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Yohimbe

What is Yohimbe?

Yohimbe
  • Erectile dysfunction
  • Low sex drive
  • Sexual performance
  • Weight loss
  • Athletic performance

Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription form of yohimbine has some evidence for erectile dysfunction, but over-the-counter yohimbe supplements vary widely in content and can cause serious side effects like high blood pressure and fast heart rate. Because of these safety concerns, talk to your pharmacist or doctor before using it.

Pausinystalia johimbe · Rubiaceae · Bark · Capsules, tablets, extracts, teas

An interaction check asks whether these two react with each other — it does not ask whether Yohimbe is a good idea for someone in your situation. Here is what our Yohimbe record says about it on its own.

Yohimbe: dosing

There is no well-established safe and standardized dose for yohimbe bark supplements. Because the yohimbine content varies so much between products, the same labeled dose can produce very different effects.If you choose to use a product, follow the directions on the label and do not exceed them. Prescription yohimbine is a separate, dose-controlled medicine and should only be used as directed by a healthcare provider.

From our Yohimbe monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yohimbe monograph & all interactions
Medication

About Albuterol

What Is Albuterol Used For?

Brand names: Ventolin, Salvent, Salmol, Airomir, Asmasal Clickhaler, Salamol Easi-Breathe, Ventmax SR, Volmax, Ventolin Syrup, Ventolin Injection, Ventolin Evohaler, Ventolin Accuhaler, Ventolin Nebules, Ventolin Respirator Solution, Salapin, Salamol, Easyhaler Salbutamol, Pulvinal Salbutamol, Salbutamol Cyclocaps, Salamol Steri-Neb

Albuterol is used to treat or prevent bronchospasm — sudden tightening of the airways — in adults and children with reversible obstructive airway disease, such as asthma. Most inhaled formulations (HFA inhalers, dry-powder inhalers, and nebulizer solutions) are approved for patients 4 years and older, though some nebulizer solutions are approved for children as young as 2, and the oral syrup covers adults and children 2 and older. Albuterol tablets are approved for adults and children 6 and older.

Albuterol inhaled products are also used to prevent exercise-induced bronchospasm in patients 4 years and older. The inhaled aerosol solution (0.5%) is approved specifically for relief of bronchospasm and acute attacks in patients 12 and older. Not every formulation covers every use — follow the instructions for the specific product you have been prescribed.

See full Albuterol drug information
Keep checking

Other Drugs & Yohimbe

Browse every other medication we’ve checked against Yohimbe — both the ones with a known interaction and the ones without. Select any drug for the full detail.

9Major
680Moderate
436Minor
1,704No known interaction
9 Major 680 Moderate 436 Minor 1,704 No interaction
Major

9 interactions

Moderate

680 interactions

Showing 60 of 680 moderate interactions — see all 680 on the Yohimbe page.

Minor

436 interactions

Showing 60 of 436 minor interactions — see all 436 on the Yohimbe page.

No interaction 1,704 drugs checked — show the list

We also checked Yohimbe against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,704 medications checked with no known interaction — see the full Yohimbe list.

See the full Yohimbe interactions page
See every supplement checked against Salbutamol Sulfate, ranked by severity
Evidence & sources

Yohimbe References

The 66 references that drive our Yohimbe monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  6. Teloken C, Rhoden EL, Sogari P, et al. Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J Urol 1998;159:122-4. PubMed
  7. Jacobsen FM. Fluoxetine-induced sexual dysfunction and an open trial of yohimbine. J Clin Psychiatry 1992;53:119-22.
  8. Hollander E, McCarley A. Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. J Clin Psychiatry 1992;53:207-9.
  9. Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed
  10. Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
  11. VandenBrink, B. M., Foti, R. S., Rock, D. A., Wienkers, L. C., and Wahlstrom, J. L. Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition. Drug Metab Dispos. 2012;40(1):47-53. PubMed
  12. Abebe, W. An overview of herbal supplement utilization with particular emphasis on possible interactions with dental drugs and oral manifestations. J Dent.Hyg. 2003;77(1):37-46.
  13. Mustonen, P., Savola, J., and Lassila, R. Atipamezole, an imidazoline-type alpha(2)-adrenoceptor inhibitor, binds to human platelets and inhibits their adrenaline-induced aggregation more effectively than yohimbine. Thromb.Res 8-1-2000;99(3):231-237.
  14. Cameron, O. G., Zubieta, J. K., Grunhaus, L., and Minoshima, S. Effects of yohimbine on cerebral blood flow, symptoms, and physiological functions in humans. Psychosom.Med 2000;62(4):549-559. PubMed
  15. Bowes, M. P., Peters, R. H., Kernan, W. J., Jr., and Hopper, D. L. Effects of yohimbine and idazoxan on motor behaviors in male rats. Pharmacol.Biochem.Behav. 1992;41(4):707-713.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Yohimbe and Salbutamol Sulfate Together: Common Questions

Is it safe to take Yohimbe with Salbutamol Sulfate?
We do not list a known interaction between Yohimbe and Salbutamol Sulfate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Yohimbe and Salbutamol Sulfate have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Yohimbe and Salbutamol Sulfate combination checked?
Interactions in our licensed database are recorded against drug classes. Salbutamol Sulfate is filed under 2 classifications, and Yohimbe has documented interactions with 13 drug classes — none of Salbutamol Sulfate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Yohimbe interact with any other medications?
Yes. Yohimbe has 1,125 documented drug interactions in our database — Salbutamol Sulfate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Salbutamol Sulfate interact with any supplements?
Yes. Salbutamol Sulfate has documented interactions with 32 supplements in our database — Yohimbe is not one of them. The Salbutamol Sulfate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Yohimbe monograph Uses, safety profile, and every drug interaction in one place Albuterol drug information The full plain-English guide to this medication Salbutamol Sulfate supplement interactions Every supplement checked against Salbutamol Sulfate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 66 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Salbutamol Sulfate and Yohimbe?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.