Herb & supplement monograph

Kiwi Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Kiwi interacts with medications. The heart of this page is the interaction list — every drug Kiwi is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Kiwi is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Kiwi Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Kiwi drug interaction appears low for most people. None of the listed interactions are rated major or well documented in humans; all are moderate concerns supported mainly by limited or theoretical evidence.

Interactions deserving the most attention

The two areas worth watching both come from small studies of kiwi itself. Because kiwi may make blood platelets less sticky, it could in theory add to the bleeding risk of blood thinners such as warfarin, aspirin, or clopidogrel. Kiwi has also been shown to modestly lower blood pressure in people with hypertension, so eating a lot of it alongside blood pressure medications could, in theory, drop pressure further than intended. Neither effect has been confirmed as harmful in people taking these medicines.

What the rest of the list means

Although the list of interacting medications looks long, it reflects just these two broad drug groups, and the concerns are largely theoretical. Kiwi's effects on platelets and blood pressure were seen in research on the fruit alone, and no human studies have shown meaningful problems when it is combined with these medicines. Typical amounts of kiwi in the diet are unlikely to cause trouble for most people.

Check your medications against Kiwi

Based on HelloPharmacist’s Kiwi interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Kiwi

289 medications have a known interaction with Kiwi, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AbciximabReoPro› AbrocitinibCibinqo› AcebutololRhotral, Sectral› AcenocoumarolSintrom› Acetaminophen, AspirinGemnisyn› Acetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine› Acetaminophen, IbuprofenCombogesic› AcetazolamideAk-Zol, Diamox› Acetylsalicylic AcidEntrophen› AliskirenTekturna› Alteplase, TpaActilyse, Activase› Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2› Aluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin› AmbrisentanLetairis, Volibris› AmilorideAmilamont, Midamor› Amiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic› AmlodipineNorliqva› Amlodipine BenzoateKaterzia› Amlodipine BesilateIstin› Amlodipine BesylateNorvasc› Amlodipine Besylate, BenazeprilLotrel› Amlodipine, CelecoxibConsensi› Ammonium ChlorideAmmonium Chloride› Anacaulase-bcdbNexoBrid› AnagrelideAgrylin› AnisindioneMiradon› Antithrombin IiiThrombate III› ApixabanEliquis› AprocitentanTryvio› ArgatrobanArgatroban›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Kiwi combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Kiwi affects

Every type of medication (drug category) Kiwi is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 2 drug categories Kiwi interacts with
Anticoagulant/antiplatelet DrugsAntihypertensive Drugs
Anticoagulant/Antiplatelet Drugs

Clinical research suggests that kiwi inhibits platelet aggregation. Theoretically, kiwi might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Clinical research suggests that consuming kiwi reduces systolic and diastolic blood pressure in hypertensive individuals. Theoretically, concomitant use of kiwi and antihypertensive drugs may increase the risk of hypotension when used in combination with drugs that lower blood pressure. These include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Likelihood Possible Evidence D
Monograph

Kiwi: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is for helping with constipation and overall digestive regularity, while other uses like better sleep or immune support are far less proven. People with a known kiwi or latex allergy should avoid it.

Scientific name
Actinidia deliciosa
Family
Actinidiaceae
Part used
Fruit (and seeds)
Common forms
Fresh fruit, dried fruit, juice, extracts, capsules, powders
People commonly use it for
  • Constipation and digestive health
  • Vitamin C and antioxidant support
  • Sleep support
  • Immune support
  • Heart and cholesterol health

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

Kiwi is safe for most people when eaten as a normal food.

PregnancyLikely Safe

When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid...

Read the full pregnancy detail
BreastfeedingLikely Safe

When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Kiwi, sometimes called kiwifruit, is a small fruit with fuzzy brown skin and bright green or golden flesh dotted with tiny black seeds. It comes from a woody climbing vine in the genus Actinidia. The most common types are the green kiwi (Actinidia deliciosa) and the golden kiwi (Actinidia chinensis).

Although it is often linked with New Zealand, the plant originally came from China and is now grown in many warm parts of the world, including Italy, Chile, and the United States. Kiwi is mostly eaten as a fresh fruit, but it is also sold as juice, dried fruit, powders, and capsules marketed as supplements.

People enjoy kiwi both for its taste and for its nutrition. It is naturally high in vitamin C, fiber, vitamin K, potassium, and various plant antioxidants.

How it works

Kiwi contains a mix of nutrients that may explain its effects. Its fiber adds bulk and holds water in the stool, which can help keep bowel movements regular. Kiwi also contains an enzyme called actinidin that may help break down proteins and support digestion.

The fruit is rich in vitamin C and other antioxidants, which help protect cells from a type of damage called oxidative stress. It also provides potassium and vitamin K.

Many of the proposed benefits beyond digestion are based on laboratory studies, animal research, or small human studies. These findings help explain why kiwi might be healthy, but they do not prove that eating it treats any disease.

Effectiveness

Does Kiwi work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 4 uses evaluated
4 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Kiwi, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 4 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Asthma
Rating & evidence shown verbatim from Natural Medicines

There is some evidence that consumption of vitamin C-rich citrus fruits, including kiwi and others, might improve lung function in people with asthma. Intake of citrus fruits 1-2 times per week has produced this benefit in some studies. However, other studies have not found this benefit.

Sources Ref 6049 Ref 6055 Ref 6056 Ref 6057 Ref 6058
Insufficient Reliable Evidence To Rate Constipation
Rating & evidence shown verbatim from Natural Medicines

Preliminary clinical research shows that consuming two kiwi fruits daily for 4 weeks increases the number of complete spontaneous bowel movements from 2.2 to 4.4 per week, and improves bothersomeness and satisfaction, but not straining, when compared with baseline in adults with constipation. The validity of this finding is limited by the lack of a comparator group.

Sources Ref 57530
Insufficient Reliable Evidence To Rate Hypertension
Rating & evidence shown verbatim from Natural Medicines

Preliminary clinical research shows that consuming three kiwi fruits daily for 8 weeks reduces 24-hour ambulatory systolic blood pressure by 3.6 mmHg and diastolic blood pressure by 1.9 mm Hg in patients with mild hypertension when compared with those consuming one apple daily.

Sources Ref 57648
Insufficient Reliable Evidence To Rate Irritable bowel syndrome (IBS)
Rating & evidence shown verbatim from Natural Medicines

Preliminary clinical research shows that consuming two kiwi fruits daily for 4 weeks decreases bowel transit time by approximately 8 hours and increases defecation frequency in patients with constipation-predominant IBS when compared to baseline. However, fecal volume does not appear to change. Other preliminary clinical research in patients with constipation-predominant IBS shows that consuming three kiwi fruits daily for 4 weeks increases the number of complete spontaneous bowel movements per week by around 2.5 and improves symptoms of constipation and pain when compared to baseline. The validity of these findings is limited by the lack of control groups.

Sources Ref 57571 Ref 103293

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

For most people, kiwi is safe and healthy to eat as part of a normal diet. The main concern is allergy. Kiwi is a known food allergen, and some people react to it. Those with a latex allergy may also react to kiwi because of a condition called latex-fruit syndrome.

Allergic reactions can range from itching or tingling in the mouth to more serious, whole-body reactions. If you have ever had an allergic reaction to kiwi, avoid it.

Pregnancy: Eating kiwi as a normal food is generally considered fine during pregnancy. Concentrated kiwi supplements have not been well studied, so it is best to check with your doctor before using them.

Breastfeeding: Kiwi as a food is likely fine while breastfeeding. As with pregnancy, supplement-strength kiwi products have not been studied, so use caution and ask your healthcare provider.

Because kiwi contains vitamin K, people who are managing their diet for specific medical reasons should keep their intake fairly steady and talk with their pharmacist or doctor.

Side effects

When eaten as a food, kiwi is well tolerated by most people. Eating large amounts may cause mild digestive effects such as gas, loose stools, or stomach upset, partly because of its fiber content.

Some people notice a tingling or itchy feeling in the mouth after eating kiwi. This can be a sign of a mild allergy. Serious allergic reactions are possible and may include swelling of the lips, tongue, or throat, trouble breathing, hives, or fainting. If this happens, seek emergency medical care right away.

The tiny black seeds and the skin are edible, but some people find them irritating to the stomach or hard to digest.

Kiwi: Reported Adverse Effects

Documented safety reports on Kiwi from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, kiwi fruit is generally well tolerated. Eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including dysphagia, urticaria, dermatitis, angioedema, and vomiting immediately following ingestion in some patients. Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis. Anaphylactic reactions and kiwi allergy-induced asthma exacerbations have also been reported after eating kiwi fruit.

Topically, kiwi can cause contact urticaria. Topical application of kiwi may also cause hypersensitivity reactions, which are more common in patients who are allergic to latex.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
  3. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205.
  4. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121.
  5. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428.
  6. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
  7. Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
  8. Rademaker, M. Allergic contact dermatitis from kiwi fruit vine (actinidia chinensis). Contact Dermatitis 1996;34(3):221-222.
  9. Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30.
  10. Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97.
  11. Veraldi, S. and Schianchi-Veraldi, R. Contact urticaria from kiwi fruit. Contact Dermatitis 1990;22(4):244.
  12. Garcia, B. E., de la Cuesta, C. G., Santos, F., Feliu, X., and Cordoba, H. A rare case of food allergy: monosensitivity to kiwi (Actinidia chinensis). Allergol.Immunopathol.(Madr.) 1989;17(4):217-218.
  13. Gastaminza, G., Bernaola, G., and Camino, M. E. Acute pancreatitis caused by allergy to kiwi fruit. Allergy 1998;53(11):1104-1105.
  14. Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44.
  15. Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
  16. Falliers, C. J. Anaphylaxis to Kiwi fruit and related "exoti"" items. J.Asthma 1983;20(3):193-196.
  17. Shimizu, T. and Morikawa, A. Anaphylaxis to kiwi fruit in a 12-year-old boy. J.Asthma 1995;32(2):159-160.
  18. Novembre, E., Bernardini, R., Bertini, G., Massai, G., and Vierucci, A. Skin-prick-test-induced anaphylaxis. Allergy 1995;50(6):511-513.
  19. Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91.
  20. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13.
  21. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7.
Reports by condition
Allergic rhinitis (hay fever) Immunologic

Eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including dysphagia, urticaria, dermatitis, angioedema, and vomiting immediately following ingestion in some patients. Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis. Anaphylactic reactions and kiwi allergy-induced asthma exacerbations have also been reported after eating kiwi fruit. Some observational research suggests that anaphylaxis after consuming kiwi fruit is more common when compared with other fruits, especially in children. Of 250 patients reporting to the emergency department for fruit-induced anaphylaxis, around 16% reported kiwi fruit as the culprit, followed by banana (11%) and mango (9%). Rarely, exercise may trigger an anaphylactic reaction to kiwi fruit in individuals with no history of kiwi fruit allergy.

Topically, kiwi can cause contact urticaria. Topical application of kiwi may also cause hypersensitivity reactions, which are more common in patients who are allergic to latex.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
  3. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205.
  4. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121.
  5. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428.
  6. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
  7. Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
  8. Rademaker, M. Allergic contact dermatitis from kiwi fruit vine (actinidia chinensis). Contact Dermatitis 1996;34(3):221-222.
  9. Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30.
  10. Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91.
  11. Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97.
  12. Veraldi, S. and Schianchi-Veraldi, R. Contact urticaria from kiwi fruit. Contact Dermatitis 1990;22(4):244.
  13. Garcia, B. E., de la Cuesta, C. G., Santos, F., Feliu, X., and Cordoba, H. A rare case of food allergy: monosensitivity to kiwi (Actinidia chinensis). Allergol.Immunopathol.(Madr.) 1989;17(4):217-218.
  14. Gastaminza, G., Bernaola, G., and Camino, M. E. Acute pancreatitis caused by allergy to kiwi fruit. Allergy 1998;53(11):1104-1105.
  15. Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44.
  16. Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
  17. Falliers, C. J. Anaphylaxis to Kiwi fruit and related "exoti"" items. J.Asthma 1983;20(3):193-196.
  18. Shimizu, T. and Morikawa, A. Anaphylaxis to kiwi fruit in a 12-year-old boy. J.Asthma 1995;32(2):159-160.
  19. Novembre, E., Bernardini, R., Bertini, G., Massai, G., and Vierucci, A. Skin-prick-test-induced anaphylaxis. Allergy 1995;50(6):511-513.
  20. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13.
  21. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7.
Allergic rhinitis (hay fever) Pulmonary/Respiratory

Orally, anaphylactic reactions and kiwi allergy-induced asthma exacerbations have been reported after eating kiwi fruit.

  1. Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44.
  2. Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97.
  3. Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
  4. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
  5. Falliers, C. J. Anaphylaxis to Kiwi fruit and related "exoti"" items. J.Asthma 1983;20(3):193-196.
  6. Shimizu, T. and Morikawa, A. Anaphylaxis to kiwi fruit in a 12-year-old boy. J.Asthma 1995;32(2):159-160.
  7. Novembre, E., Bernardini, R., Bertini, G., Massai, G., and Vierucci, A. Skin-prick-test-induced anaphylaxis. Allergy 1995;50(6):511-513.
  8. Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
  9. Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30.
  10. Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91.
Allergic rhinitis (hay fever) Gastrointestinal

Orally, eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, throat, and tongue, including dysphagia and vomiting immediately following ingestion in some patients. Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97.
  3. Veraldi, S. and Schianchi-Veraldi, R. Contact urticaria from kiwi fruit. Contact Dermatitis 1990;22(4):244.
  4. Garcia, B. E., de la Cuesta, C. G., Santos, F., Feliu, X., and Cordoba, H. A rare case of food allergy: monosensitivity to kiwi (Actinidia chinensis). Allergol.Immunopathol.(Madr.) 1989;17(4):217-218.
  5. Gastaminza, G., Bernaola, G., and Camino, M. E. Acute pancreatitis caused by allergy to kiwi fruit. Allergy 1998;53(11):1104-1105.
Dermatitis Dermatologic

Orally, eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including urticaria, dermatitis, and angioedema in some patients.

Topically, kiwi can cause contact urticaria. Topical application of kiwi may also cause hypersensitivity reactions, which are more common in patients who are allergic to latex.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
  3. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205.
  4. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121.
  5. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428.
  6. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
  7. Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
  8. Rademaker, M. Allergic contact dermatitis from kiwi fruit vine (actinidia chinensis). Contact Dermatitis 1996;34(3):221-222.
  9. Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30.
  10. Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91.
  11. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13.
  12. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no official or standardized dose of kiwi for any health condition. In studies on digestion and sleep, people often ate about one to two kiwifruit per day, but this is not a formal medical recommendation.

For kiwi supplements, juices, or powders, follow the directions on the product label, since the amount of active ingredients varies widely between products. Supplements are not closely regulated, so quality can differ between brands.

If you are thinking about using kiwi supplements for a specific health reason, talk with your pharmacist or doctor first. Simply enjoying kiwi as a fruit is a safe and easy way to get its nutrients.

Pregnancy & Breastfeeding

Kiwi & Pregnancy

Likely Safe

When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid use.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

Kiwi & Breastfeeding

Likely Safe

When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid use.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 32 references that drive our Kiwi monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
  3. Forastiere F, Pistelli R, Sestini P, et al. Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children. Thorax 2000;55:283-8. DOI
  4. Carey IM, Strachan DP, Cook DG. Effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med 1998;158:728-33. PubMed
  5. Schwartz J, Weiss ST. Relationship between dietary vitamin C intake and pulmonary function in the First National Health and Nutrition Examination Survey (NHANES I). Am J Clin Nutr 1994;59:110-4. PubMed
  6. Butland BK, Fehily AM, Elwood PC. Diet, lung function, and lung function decline in a cohort of 2512 middle aged men. Thorax 2000;55:102-8. PubMed
  7. Troisi RJ, Willett WC, Weiss ST, et al. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 1995;151:1401-8. PubMed
  8. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
  9. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
  10. Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44. PubMed
  11. Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97. PubMed
  12. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205. PubMed
  13. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428. PubMed
  14. Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
  15. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Kiwi

130 brands in our database make a supplement containing Kiwi.

Product directory

Supplement products with Kiwi

374 products in our database contain Kiwi. Open any to see its full ingredient list and every drug interaction we check.

Tropical Superfoods by Terra Origin Powder 9.52 Ounce(s) · 270 Gram(s) View ingredients & interactions TrueLife PB by NatureCity Capsule 30 Vegetarian Capsule(s) View ingredients & interactions TrueLife PB by NatureCity Capsule 30 Vegetarian Capsule(s) View ingredients & interactions Ultimate Man by The Vitamin Shoppe Tablet Or Pill 180 Tablet(s) View ingredients & interactions Ultimate Man by The Vitamin Shoppe Tablet Or Pill 90 Tablet(s) View ingredients & interactions Ultimate Man by The Vitamin Shoppe Tablet Or Pill 180 Tablet(s) View ingredients & interactions Ultimate Man by The Vitamin Shoppe Tablet Or Pill 108 Tablet(s) View ingredients & interactions Ultimate Woman by The Vitamin Shoppe Tablet Or Pill 108 Tablet(s) View ingredients & interactions Ultimate Woman by The Vitamin Shoppe Tablet Or Pill 90 Tablet(s) View ingredients & interactions Ultimate Woman by The Vitamin Shoppe Tablet Or Pill 180 Tablet(s) View ingredients & interactions Ultimate Woman No Iron by The Vitamin Shoppe Tablet Or Pill 180 Tablet(s) View ingredients & interactions Ultimate Woman No Iron by The Vitamin Shoppe Tablet Or Pill 90 Tablet(s) View ingredients & interactions Ultra Mega Without Iron & Iodine by GNC Women's Other (e.g. Tea Bag) 90 Caplet(s) View ingredients & interactions Ultra Mega Without Iron & Iodine by GNC Women's Other (e.g. Tea Bag) 180 Caplet(s) View ingredients & interactions Vegan K2 + D3 by NATURELO Premium Supplements Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Vegan K2 + D3 by NATURELO Capsule 60 Vegetarian Capsule(s) View ingredients & interactions VitaComplete by Vitabase Liquid 32 fl. Oz. View ingredients & interactions Vitamin C Complex by Gematria Capsule 180 Capsule(s) View ingredients & interactions Vitamin D3 2000IU and K2 80 mcg by FREZZOR Capsule 60 Capsule(s) View ingredients & interactions Vitamin E 180 mg by NATURELO Premium Supplements Capsule 90 Vegetarian Capsule(s) View ingredients & interactions Vitamin E 180 mg by NATURELO Premium Supplements Capsule 90 Vegetarian Capsule(s) View ingredients & interactions VitaMode by Evlution Nutrition Tablet Or Pill 120 Tablet(s) View ingredients & interactions VitaMode by Evlution Nutrition Tablet Or Pill 120 Tablet(s) View ingredients & interactions Whey Protein 100% Grass-Fed Creamy Vanilla by FREZZOR Powder 600 Gram(s) View ingredients & interactions
Pharmacist Counseling Corner

Kiwi: Common Questions

What is Kiwi used for, and does it work?
People use Kiwi for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Kiwi interact with prescription medications?
Yes. We list 289 medications with a known interaction with Kiwi. Use the checker above to see how Kiwi interacts with a specific drug.
How are Kiwi interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Kiwi with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Kiwi interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Kiwi good for constipation?
Kiwi is one of the better-studied foods for mild constipation, and eating it regularly may help keep bowel movements regular thanks to its fiber and natural compounds. Results vary, so talk to your doctor if constipation is ongoing.
Can I eat the Kiwi skin and seeds?
Yes, the skin and seeds are edible and add extra fiber, though some people prefer to peel Kiwi because they don't like the fuzzy texture. If the skin or seeds upset your stomach, it's fine to skip them.
Can Kiwi cause an allergic reaction?
Yes. Kiwi is a known food allergen and can cause anything from mild mouth itching to serious reactions. People with a latex allergy may be more likely to react to Kiwi and should be cautious.
Does eating Kiwi before bed help you sleep?
A few small studies have looked at this, with some positive results, but the evidence is limited and not strong enough to recommend Kiwi as a sleep aid. It may be worth trying as a healthy bedtime snack, but don't rely on it to fix sleep problems.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Keep exploring

Products that contain Kiwi

A rotating sample of real supplements in our database that list Kiwi — open any to see its full ingredients and every drug interaction we check.

See all 374 products with Kiwi →
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