Drug Interactions Directory

2,618 drugs with documented interactions.

2,618Drugs
67,117Interactions
53,805Serious (major+)
PharmacistReviewed
1Look up a drugSearch by generic or brand name, or browse A-Z.
2Scan the severityInteractions are grouped and color-coded by how much they matter.
3Read the write-upPlain-English and clinical explanations, with cited evidence.
Popular: Buprenorphine 633 Hydroxychloroquine 631 Ketoconazole Topical 546 Cyclosporine Injection 545 Cyclosporine Ophthalmic 545 Sertraline 532 Amitriptyline 525 Fentanyl Transdermal Patch 493

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

E
Etonogestrel 25 Etoposide 4 Etoricoxib 93 Etozolin 44 Etrasimod 81 Etravirine 81 Etretinate 7 Etuvetidigene Autotemcel 14 Eucalyptus 7 Evening Primrose 23 Everolimus 185 Exagamglogene Autotemcel 4 Exemestane 32 Exenatide 80 Exenatide Injection 133 Ezetimibe 29 Ezogabine 5
F
Fam-Trastuzumab Deruxtecan-Nxki Injection 15 Famotidine 217 Famotidine Injection 192 Fazadinium 8 Febuxostat 17 Fedratinib 106 Felbamate 199 Felbinac 91 Felodipine 125 Femoxetine 2 Fenbufen 3 Fenfluramine 19 Fenofibrate 16 Fenofibric Acid 16 Fenoldopam 15 Fenoprofen 290 Fenoterol 1 Fenquizone 2 Fentanyl 64 Fentanyl Transdermal Patch 493 Fenugreek 13 Fepradinol 91 Feprazone 91 Ferric Ammonium Citrate 1 Ferric Carboxymaltose 1 Ferric Citrate 1 Ferric Pyrophosphate Citrate 1 Ferrous Fumarate 1 Ferrous Gluconate 1 Ferrous Sulfate 2 Fesoterodine 13 Feverfew 37 Fexinidazole 157 Fexofenadine 39 Fezolinetant 19 Finerenone 218 Fingolimod 74 Flavoxate 12 Flecainide 300 Fleroxacin 9 Flesinoxan 1 Flibanserin 54 Floctafenine 91 Floxuridine 15 Flucloronide 5 Flucloxacillin 12 Fluconazole 166 Flucytosine 6 Fludarabine 1 Fludarabine Injection 17 Fludrocortisone 17 Fludrocortisone Acetate 86 Flufenamic Acid 91 Fluindione 5 Flumazenil 4 Flumequine 13 Flumethasone 6 Flunarizine 1 Flunisolide 6 Flunisolide Nasal Spray 30 Flunisolide Oral Inhalation 30 Flunitrazepam 14 Fluocinolone 30 Fluocinolone Topical 27 Fluocinonide 30 Fluocinonide Topical 27 Fluocortin 4 Fluocortolone 16 Fluoroestradiol F 18 3 Fluorometholone 6 Fluorouracil 90 Fluorouracil Injection 77 Fluorouracil Topical 77 Fluoxetine 142 Fluoxymesterone 8 Flupenthixol 2 Fluphenazine 32 Flurandrenolide 5 Flurandrenolide Topical 22 Flurazepam 22 Flurbiprofen 299 Flurbiprofen Ophthalmic 263 Fluspirilene 20 Flutamide 24 Fluticasone 14 Fluticasone Propionate 1 Fluvastatin 76 Fluvoxamine 113 Folic Acid 94 Fondaparinux 204 Fondaparinux Injection 180 Formoterol 79 Formoterol Fumarate 1 Fosamprenavir 75 Fosaprepitant 55 Foscarbidopa 20 Foscarnet 80 Foscarnet Injection 259 Fosfomycin 63 Fosinopril 193 Foslevodopa 21 Fosnetupitant 78 Fosphenytoin 267