Medication interaction hub

What Supplements Interact with Aspirin, Methocarbamol?

Aspirin, Methocarbamol brand name: Robaxisal. Every interaction below applies to the brands too.

243 Interactions 8 Major 207 Moderate 28 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Aspirin, Methocarbamol? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Aspirin, Methocarbamol against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Robaxisal combines aspirin with methocarbamol, a muscle relaxant, and the aspirin half is why this list warrants real attention rather than a shrug. Of the 243 supplement ingredients on file, the overwhelming majority (more than 200) can add to aspirin's blood-thinning effect and raise the risk of bleeding. Eight are rated major, and they include something as ordinary as the alcohol in beer or wine, which raises the chance of stomach bleeding when taken alongside aspirin.

The rest of the list splits into smaller themes. Some ingredients, like activated charcoal and bulking fibers such as glucomannan, can blunt absorption of oral doses and should be spaced well apart. A handful stress the kidneys, and a few add to methocarbamol's muscle-relaxing effect. With 207 moderate and 28 minor entries, most pairings are manageable, but the eight majors, especially alcohol, are where the real danger sits.

— , Clinical Pharmacist · July 18, 2026

Major 8 Moderate 207 Minor 28 No known interaction 1,209

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Aspirin, Methocarbamol: Top Interactions at a Glance

The Aspirin, Methocarbamol supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 243 interacting ingredients — plus 1,209 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Aspirin, Methocarbamol Combinations Today

The Aspirin, Methocarbamol + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Unlikely Blue-green Algae + Aspirin, Methocarbamoli

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Terminalia + Aspirin, Methocarbamoli

Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.

Read the full interaction Moderate Likelihood Possible Kudzu + Aspirin, Methocarbamoli

Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.

Read the full interaction Moderate Likelihood Possible Plum + Aspirin, Methocarbamoli

Theoretically, plum juice might have antiplatelet effects.

Read the full interaction Moderate Likelihood Possible Cod Liver Oil + Aspirin, Methocarbamoli

Theoretically, cod liver oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Indole-3-carbinol + Aspirin, Methocarbamoli

Theoretically, indole-3-carbinol might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Aspirin, Methocarbamol

All 1,452 ingredients in our database, ranked by severity — 243 with a Aspirin, Methocarbamol interaction on file and 1,209 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Aspirin, Methocarbamol?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Blue-green Algae with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.

Full Blue-green Algae + Aspirin, Methocarbamol answer

Can you take Terminalia with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patie...

Full Terminalia + Aspirin, Methocarbamol answer

Can you take Kudzu with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.

Full Kudzu + Aspirin, Methocarbamol answer

Can you take Plum with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, plum juice might have antiplatelet effects.

Full Plum + Aspirin, Methocarbamol answer

Can you take Cod Liver Oil with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cod liver oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Cod Liver Oil + Aspirin, Methocarbamol answer

Can you take Parsley with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Parsley + Aspirin, Methocarbamol answer

Can you take Pau D'arco with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Pau D'arco + Aspirin, Methocarbamol answer

Can you take Peony with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Full Peony + Aspirin, Methocarbamol answer

Can you take Phellodendron with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Phellodendron + Aspirin, Methocarbamol answer

Can you take Policosanol with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking policosanol with other antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.

Full Policosanol + Aspirin, Methocarbamol answer

Can you take Propolis with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, propolis might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.

Full Propolis + Aspirin, Methocarbamol answer

Can you take Pu-erh Tea with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, pu-erh tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Pu-erh Tea + Aspirin, Methocarbamol answer

Can you take Puravive with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Puravive, a dietary supplement, contains several ingredients that may interact with anticoagulant drugs due to their potential mild anticoag...

Full Puravive + Aspirin, Methocarbamol answer

Can you take Purple Nut Sedge with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge inhibits platelet aggregation.

Full Purple Nut Sedge + Aspirin, Methocarbamol answer

Can you take Quercetin with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the effects and adverse effects of OAT3 substrates.

Full Quercetin + Aspirin, Methocarbamol answer

Can you take Rauwolscine with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rauwolscine may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet dr...

Full Rauwolscine + Aspirin, Methocarbamol answer

Can you take Red Raspberry with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.

Full Red Raspberry + Aspirin, Methocarbamol answer

Can you take Reishi Mushroom with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of reishi mushroom might increase the risk of bleeding.

Full Reishi Mushroom + Aspirin, Methocarbamol answer

Can you take Resveratrol with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Resveratrol + Aspirin, Methocarbamol answer

Can you take Rhubarb with Aspirin, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.

Full Rhubarb + Aspirin, Methocarbamol answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aspirin, Methocarbamol is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aspirin, Methocarbamol, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aspirin, Methocarbamol sits in 8 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Aspirin 22 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

22 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Skeletal Muscle Relaxants 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Aspirin, Methocarbamol through this category.

Related: does Aspirin, Methocarbamol deplete any nutrients?

Aspirin, Methocarbamol has 4 reported nutrient associations in the research literature — see the Aspirin, Methocarbamol nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aspirin, Methocarbamol

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aspirin, Methocarbamol.

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Pharmacist Counseling Corner

Aspirin, Methocarbamol & Supplements: Common Questions

What supplements interact with Aspirin, Methocarbamol?
More than you might expect — 243 in total, though they are far from equal: 8 are rated major, 207 moderate, and 28 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Siberian Cocklebur, Activated Charcoal, Beer.
Which Aspirin, Methocarbamol supplement interactions are the most serious?
The 8 major-rated combinations — led by Siberian Cocklebur, Activated Charcoal, Beer, Danshen and Piracetam — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Aspirin, Methocarbamol?
Usually yes — most people on Aspirin, Methocarbamol can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Robaxisal have the same supplement interactions as Aspirin, Methocarbamol?
Yes — Robaxisal all contain Aspirin, Methocarbamol, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Aspirin, Methocarbamol deplete any vitamins or nutrients?
It might — Aspirin, Methocarbamol has 4 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Aspirin, Methocarbamol nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Aspirin, Methocarbamol and my other medications?
This page covers Aspirin, Methocarbamol against supplements and herbal ingredients. Checking Aspirin, Methocarbamol against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.