Drug Interactions Directory

2,618 drugs with documented interactions.

2,618Drugs
67,117Interactions
53,805Serious (major+)
PharmacistReviewed
1Look up a drugSearch by generic or brand name, or browse A-Z.
2Scan the severityInteractions are grouped and color-coded by how much they matter.
3Read the write-upPlain-English and clinical explanations, with cited evidence.
Popular: Buprenorphine 633 Hydroxychloroquine 631 Ketoconazole Topical 546 Cyclosporine Injection 545 Cyclosporine Ophthalmic 545 Sertraline 532 Amitriptyline 525 Fentanyl Transdermal Patch 493

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

M
Modafinil 59 Moexipril 194 Mogamulizumab-Kpkc Injection 15 Molindone 21 Momelotinib 13 Mometasone 45 Mometasone Nasal Spray 41 Mometasone Oral Inhalation 41 Mometasone Topical 41 Montelukast 18 Moricizine 59 Morniflumate 91 Morphine 73 Morphine Injection 437 Morphine Sulfate Liposome 72 Mosunetuzumab-Axgb Injection 15 Motherwort 16 Moxalactam 2 Moxetumomab Pasudotox-Tdfk Injection 15 Moxifloxacin 322 Moxifloxacin Injection 282 Moxifloxacin Ophthalmic 282 Moxisylyte 16 Moxonidine 10 Mumps Virus Vaccine, Live 204 Mycophenolate Mofetil 29 Mycophenolic Acid 19
N
Nabumetone 289 Nadifloxacin 12 Nadolol 195 Nadroparin 89 Nafarelin 18 Nafarelin Nasal Spray 85 Nafcillin 66 Nafcillin Injection 197 Nalbuphine 36 Nalbuphine Injection 257 Naldemedine 50 Nalidixic Acid 8 Nalorphine 3 Naloxegol 105 Naloxone 8 Naloxone Injection 6 Naloxone Nasal Spray 6 Naltrexone 11 Nandrolone 1 Naphazoline 1 Naproxen 309 Naratriptan 21 Natalizumab 4 Natalizumab Injection 5 Nateglinide 209 Naxitamab-Gqgk Injection 15 Nebivolol 220 Necitumumab Injection 15 Nefazodone 147 Nefopam 2 Nelarabine 1 Nelarabine Injection 16 Nelfinavir 171 Nemolizumab-Ilto 2 Neomycin 19 Neostigmine 3 Neostigmine Methylsulfate 11 Nepafenac 91 Nerandomilast 4 Neratinib 157 Nesiritide 7 Netilmicin 15 Netupitant 79 Nevirapine 163 Niacin 24 Nialamide 12 Niaprazine 1 Nicardipine 57 Nicergoline 8 Nicomorphine 29 Nicorandil 2 Nicotine 5 Nicotine Nasal Spray 5 Nicotine Transdermal Patch 5 Nifedipine 325 Niflumic Acid 91 Nilotinib 116 Nilutamide 24 Nilvadipine 1 Nimesulide 91 Nimesulide Beta Cyclodextrin 91 Nimodipine 77 Nimorazole 5 Nintedanib 67 Niraparib 15 Nirmatrelvir 72 Nirogacestat 55 Nisoldipine 86 Nitisinone 22 Nitrazepam 22 Nitrendipine 8 Nitric Oxide 5 Nitrofurantoin 13 Nitroglycerin 20 Nitroglycerin Spray 15 Nitroglycerin Sublingual 15 Nitroglycerin Topical 15 Nitroglycerin Transdermal Patch 15 Nitrous Oxide 22 Nivolumab 5 Nivolumab Injection 21 Nizatidine 48 Nomegestrol 45 Nordazepam 7 Norelgestromin 18 Norepinephrine 10 Norepinephrine Bitartrate 1 Norethandrolone 1 Norethindrone 53 Norfloxacin 114 Norgestimate 52 Norgestrel 46 Nortriptyline 82