Dapagliflozin

98 interactions 207 cited references

Also sold as: Farxiga Farxiga®

About Dapagliflozin

An SGLT2 inhibitor used to lower blood sugar in type 2 diabetes and reduce heart failure and kidney disease complications. Read the full Dapagliflozin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Furosemide Injection Gatifloxacin Ophthalmic Abiraterone Acetate Abiraterone Acetate, Micronized Cannabidiol Chlorothiazide

60 Major 38 Moderate

All (98) Major (60) Moderate (38)

Moderate

Dapagliflozin Lisinopril Prinivil An increased risk of hypoglycemia Details Dapagliflozin Atenolol Tenormin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Benazepril Lotensin An increased risk of hypoglycemia Details Dapagliflozin Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Betaxolol Ophthalmic Betoptic® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Captopril Capoten® An increased risk of hypoglycemia Details Dapagliflozin Carteolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Carvedilol Coreg Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Celiprolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Enalapril Epaned An increased risk of hypoglycemia Details Dapagliflozin Enalaprilat An increased risk of hypoglycemia Details Dapagliflozin Esmolol Brevibloc Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Fosinopril Monopril® An increased risk of hypoglycemia Details Dapagliflozin Glecaprevir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Dapagliflozin Labetalol Normodyne® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Levobunolol Betagan Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Levothyroxine Ermeza Worsening of glycemic control Details Dapagliflozin Metipranolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Metoprolol Kapspargo Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Moexipril Univasc® An increased risk of hypoglycemia Details Dapagliflozin Nadolol Corgard Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Nebivolol Bystolic Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Oxprenolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Penbutolol Levatol® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Perindopril Aceon An increased risk of hypoglycemia Details Dapagliflozin Pibrentasvir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Dapagliflozin Pindolol Visken® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Practolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Propranolol Hemangeol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Quinapril Accupril An increased risk of hypoglycemia Details Dapagliflozin Ramipril Altace An increased risk of hypoglycemia Details Dapagliflozin Sotalol Betapace Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Timolol Betimol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Dapagliflozin Trandolapril Mavik® An increased risk of hypoglycemia Details Dapagliflozin Tranylcypromine Parnate An increased risk of hypoglycemia Details Dapagliflozin Levobunolol Ophthalmic AKBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.