Medication interaction hub

What Supplements Interact with Aspirin, Dipyridamole?

Aspirin, Dipyridamole brand names: Aggrenox, Asasantin Retard. Every interaction below applies to the brands too.

243 Interactions 8 Major 206 Moderate 29 Minor

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Aspirin with dipyridamole (Aggrenox) keeps platelets from clumping to prevent a second stroke, so it should be no surprise that the great bulk of this page is about bleeding. Most listed supplements can thin the blood further, and the risk reaches into ordinary life: beer and wine both carry major ratings because alcohol alongside aspirin makes stomach bleeding more likely. This list calls for real care, beginning with the handful of major-rated entries.

A smaller cluster pulls the other way. Caffeine from coffee, tea, and guarana can blunt dipyridamole's blood vessel effects and should be stopped before a cardiac stress test. A few ingredients, activated charcoal among them, block absorption of oral drugs, and a few strain the kidneys. Of the 243 on file, 206 rate moderate and 29 minor, leaving eight majors, most tied to bleeding, kidneys, or the stress test drug adenosine, which dipyridamole makes markedly stronger.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Aspirin, Dipyridamole: Top Interactions at a Glance

The Aspirin, Dipyridamole supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 243 interacting ingredients — plus 1,209 more checked with no known interaction. See the complete ranked list.

The complete list

Every Supplement Checked Against Aspirin, Dipyridamole

All 1,452 ingredients in our database, ranked by severity — 243 with a Aspirin, Dipyridamole interaction on file and 1,209 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Straight answers

Can You Take It With Aspirin, Dipyridamole?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Yohimbe with Aspirin, Dipyridamole?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been repor...

Full Yohimbe + Aspirin, Dipyridamole answer

Can you take Kiwi with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research suggests that kiwi inhibits platelet aggregation.

Full Kiwi + Aspirin, Dipyridamole answer

Can you take Docosahexaenoic Acid (dha) with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Docosahexaenoic Acid (dha) + Aspirin, Dipyridamole answer

Can you take Terminalia with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patie...

Full Terminalia + Aspirin, Dipyridamole answer

Can you take Saw Palmetto with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.

Full Saw Palmetto + Aspirin, Dipyridamole answer

Can you take Sea Buckthorn with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Sea Buckthorn + Aspirin, Dipyridamole answer

Can you take Selenium with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Selenium + Aspirin, Dipyridamole answer

Can you take Serrapeptase with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking serrapeptase with drugs that have antiplatelet or anticoagulant effects might increase the risk of bruising and bleedi...

Full Serrapeptase + Aspirin, Dipyridamole answer

Can you take Slippery Elm with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Aspirin, Dipyridamole answer

Can you take Sorrel with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Full Sorrel + Aspirin, Dipyridamole answer

Can you take Strawberry with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro and animal research suggests that strawberry extract can inhibit platelet aggregation due to its phenolic content.

Full Strawberry + Aspirin, Dipyridamole answer

Can you take Summer Savory with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that summer savory extract inhibits platelet aggregation and adhesion.

Full Summer Savory + Aspirin, Dipyridamole answer

Can you take Swallowroot with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, swallowroot might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Swallowroot + Aspirin, Dipyridamole answer

Can you take Sweet Clover with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Sweet Clover + Aspirin, Dipyridamole answer

Can you take Sweet Vernal Grass with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hay prepared from dried sweet vernal grass contains an anticoagulant, dicoumarol, which has been associated with fatal hemorrhages in animal...

Full Sweet Vernal Grass + Aspirin, Dipyridamole answer

Can you take Tamarind with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tamarind fruit extract might increase the effects and side effects of aspirin.

Full Tamarind + Aspirin, Dipyridamole answer

Can you take Tarragon with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.

Full Tarragon + Aspirin, Dipyridamole answer

Can you take Thyme with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, thyme leaf extract might have additive effects with anticoagulant or antiplatelet drugs.

Full Thyme + Aspirin, Dipyridamole answer

Can you take Tianeptine with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Chronic use of aspirin might increase the levels and clinical effects of tianeptine.

Full Tianeptine + Aspirin, Dipyridamole answer

Can you take Tiratricol with Aspirin, Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tiratricol might increase the hypoprothrombinemic effects of oral anticoagulants.

Full Tiratricol + Aspirin, Dipyridamole answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aspirin, Dipyridamole is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aspirin, Dipyridamole, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aspirin, Dipyridamole sits in 8 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Aspirin 22 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

22 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Dipyridamole (Persantine) 13 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

13 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Dipyridamole through this category.

Related: does Aspirin, Dipyridamole deplete any nutrients?

Aspirin, Dipyridamole has 8 reported nutrient associations in the research literature — see the Aspirin, Dipyridamole nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aspirin, Dipyridamole

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aspirin, Dipyridamole.

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Pharmacist Counseling Corner

Aspirin, Dipyridamole & Supplements: Common Questions

What supplements interact with Aspirin, Dipyridamole?
In our interaction database, 243 supplement and herbal ingredients have an interaction with Aspirin, Dipyridamole on file — 8 rated major, 206 moderate, and 29 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Adenosine, Siberian Cocklebur, Activated Charcoal.
Which Aspirin, Dipyridamole supplement interactions are the most serious?
Focus on the major group: Adenosine, Siberian Cocklebur, Activated Charcoal, Beer and Danshen, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Aspirin, Dipyridamole?
That depends entirely on which supplement. The honest answer for Aspirin, Dipyridamole is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Aggrenox have the same supplement interactions as Aspirin, Dipyridamole?
Yes — Aggrenox, Asasantin Retard all contain Aspirin, Dipyridamole, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Aspirin, Dipyridamole deplete any vitamins or nutrients?
It might — Aspirin, Dipyridamole has 8 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Aspirin, Dipyridamole nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Aspirin, Dipyridamole and my other medications?
This page covers Aspirin, Dipyridamole against supplements and herbal ingredients. Checking Aspirin, Dipyridamole against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.