Herb & supplement monograph

Sorrel Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Sorrel

169 medications have a known interaction with Sorrel, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AbciximabReoPro
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Abciximab interaction
AbrocitinibCibinqo
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Abrocitinib interaction Abrocitinib drug page: uses, dosage & side effects
AcenocoumarolSintrom
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Acenocoumarol interaction
Acetaminophen, AspirinGemnisyn
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Acetaminophen, Aspirin interaction
Acetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Acetaminophen, Aspirin, Caffeine interaction
Acetaminophen, IbuprofenCombogesic
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Acetaminophen, Ibuprofen interaction
Acetylsalicylic AcidEntrophen
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Acetylsalicylic Acid interaction Acetylsalicylic Acid drug page: uses, dosage & side effects
Alteplase, TpaActilyse, Activase
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Alteplase, Tpa interaction
Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interaction
Aluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction Aluminum Hydroxide, Aspirin, Magnesium Hydroxide drug page: uses, dosage & side effects
Anacaulase-bcdbNexoBrid
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Anacaulase-bcdb interaction
AnagrelideAgrylin
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Anagrelide interaction Anagrelide drug page: uses, dosage & side effects
AnisindioneMiradon
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Anisindione interaction
Antithrombin IiiThrombate III
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Antithrombin Iii interaction
ApixabanEliquis
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Apixaban interaction Apixaban drug page: uses, dosage & side effects
ArgatrobanArgatroban
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Argatroban interaction
AspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin interaction Aspirin drug page: uses, dosage & side effects
Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interaction
Aspirin, ButalbitalAxotal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Butalbital interaction
Aspirin, Butalbital, CaffeineFiorinal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Butalbital, Caffeine interaction Aspirin, Butalbital, Caffeine drug page: uses, dosage & side effects
Aspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Butalbital, Caffeine, Codeine Phosphate interaction
Aspirin, Butalbital, Caffeine, PhenacetinMarnal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Butalbital, Caffeine, Phenacetin interaction
Aspirin, CaffeineAnacin
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine interaction
Aspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Codeine Phosphate interaction
Aspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Dihydrocodeine Bitartrate interaction
Aspirin, Caffeine, Dover's PwdAcedoval, Dovacet
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Dover's Pwd interaction
Aspirin, Caffeine, HydrocodoneDamason-P
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Hydrocodone interaction
Aspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interaction Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin drug page: uses, dosage & side effects
Aspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Orphenadrine interaction
Aspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
Moderate Anticoagulant/antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Read the full Sorrel + Aspirin, Caffeine, Phenacetin, Propoxyphene interaction
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Sorrel combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Sorrel affects

Every type of medication (drug category) Sorrel is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 3 drug categories Sorrel interacts with
Anticoagulant/antiplatelet DrugsFexofenadine (allegra)Organic Anion-transporting Polypeptide Substrates (oatp)
Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
Monograph

Sorrel: Uses, Safety & Side Effects

The bottom line

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for any health benefit is limited, and its high oxalate content means it should be used in moderation, especially by people prone to kidney stones.

Sorrel
Scientific name
Rumex acetosa
Family
Polygonaceae
Part used
Leaves (and sometimes whole aerial parts)
Common forms
Fresh leaves in cooking, tea, dried herb, tincture, and as an ingredient in some herbal combination products
People commonly use it for
  • Sinus and respiratory congestion
  • Digestive upset
  • Fever
  • Skin conditions and inflammation
  • Antioxidant support

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally safe as a food in normal amounts, but high oxalate content can be a concern with large or concentrated doses.

PregnancyPossibly Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of sorrel used in medicinal...

Read the full pregnancy detail
BreastfeedingPossibly Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of sorrel used in medicinal...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Sorrel (Rumex acetosa) is a leafy perennial herb known for its sharp, lemony, sour taste. It grows in temperate regions around the world and is a common garden and wild plant.

People most often use sorrel as a food, adding its tangy leaves to soups, sauces, and salads. It has also been used in traditional medicine, and sorrel is one of several herbs found in some popular herbal combination products marketed for sinus and respiratory health.

The sour flavor comes from oxalic acid (oxalate), the same compound that gives the herb its tartness and also raises some safety considerations.

How it works

Sorrel contains plant compounds such as flavonoids, anthraquinones, polyphenols, vitamin C, and oxalic acid. In test-tube and animal studies, some of these compounds show antioxidant and anti-inflammatory activity, and a few have shown effects against certain bacteria.

Researchers think the antioxidant compounds may help reduce cell stress, while certain components may help thin mucus, which is one reason sorrel appears in some sinus formulas. These mechanisms are largely based on laboratory research and do not prove the herb will help people.

Effectiveness

Does Sorrel work?

Evidence overview · 3 uses evaluated
3 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Sorrel, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 3 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Breast cancer
Rating & evidence shown verbatim from Natural Medicines

Oral sorrel has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Bronchitis
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral sorrel for bronchitis, there is insufficient reliable information about the clinical effects of sorrel for this condition.

Insufficient Reliable Evidence To Rate Rhinosinusitis
Rating & evidence shown verbatim from Natural Medicines

Oral sorrel has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Eaten as a food in normal amounts, sorrel is generally considered safe for most healthy people. The main concern is its high oxalate content. Large amounts or concentrated extracts can raise the risk of kidney stones and may, in rare cases, cause more serious problems.

People who should be especially careful include those with a history of kidney stones, kidney disease, gout, or rheumatoid arthritis, since oxalates may worsen these conditions. Children have become seriously ill from eating very large amounts of raw sorrel.

Pregnancy and breastfeeding: Using sorrel as a normal food ingredient is likely fine, but medicinal or concentrated amounts have not been shown to be safe. To be cautious, pregnant and breastfeeding women should avoid sorrel supplements and large medicinal doses.

Always talk with your pharmacist or doctor before using sorrel as a supplement, especially if you take other medicines or have a health condition.

Side effects

In food amounts, sorrel is usually well tolerated. Some people may have mild stomach upset, nausea, or diarrhea.

Because of its oxalate content, large or frequent doses may contribute to kidney stones or, rarely, more serious kidney problems. Very large amounts can cause more severe oxalate poisoning, which is rare but potentially dangerous. Stop use and seek medical care if you have severe stomach pain, vomiting, or symptoms of a kidney problem.

Sorrel: Reported Adverse Effects

Documented safety reports on Sorrel from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Reports by condition
Allergic rhinitis (hay fever) Pulmonary/Respiratory

Environmental exposure to sorrel pollen may trigger allergic rhinitis or bronchial asthma in hypersensitive individuals, and allergic cross-sensitivity may occur in up to 19% of people who are allergic to weed pollen.

  1. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
Hypophosphatemia Renal

Sorrel contains oxalates; irolithiasis and nephrosis may be caused by the systemic absorption of oxalates and may result in kidney damage. A case of acute tubulointerstitial nephritis (TIN) has been reported in a 12-year-old who consumed an unknown amount of wild sorrel. The patient presented with polyuria, hypophosphatemia, proteinuria, glucosuria, and hyperoxaluria. Recovery occurred after oral rehydration and electrolyte replacement. The TIN was likely due to formation of calcium oxalate crystals in the kidneys.

  1. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345.
  2. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497.
Nausea and vomiting Gastrointestinal

Orally, sorrel, when used in combination with other herbs, has been reported to cause gastrointestinal side effects including nausea and an unpleasant aftertaste.

  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no well-established standardized medicinal dose for sorrel. As a food, it is used in normal culinary amounts.

When sorrel appears in herbal supplement products, the amount varies by brand. Follow the directions on the product label and do not exceed the recommended dose. Because of the oxalate concern, it is wise to avoid taking large amounts over long periods. Check with your pharmacist or doctor before starting any sorrel supplement.

Pregnancy & Breastfeeding

Sorrel & Pregnancy

Possibly Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of sorrel used in medicinal amounts during pregnancy and lactation; avoid using.

Sorrel & Breastfeeding

Possibly Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of sorrel used in medicinal amounts during pregnancy and lactation; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 8 references that drive our Sorrel monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
  5. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
  6. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
  7. Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
  8. Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Sorrel

236 products in our database contain Sorrel. Open any to see its full ingredient list and every drug interaction we check.

Mucous Membranes Support by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Mucous Membranes Support by Herbal Terra Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions Mucous Membranes Support Alcohol Free by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Mucous Membranes Support Alcohol Free by Herbal Terra Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions MycoSoothe by PhytAge Labs Capsule 60 Capsule(s) View ingredients & interactions Ojibwa Herbal Extract 450 mg by NOW Capsule 90 Veg Capsule(s) View ingredients & interactions Ojibwa Herbal Extract 450 mg by NOW Capsule 180 Veg Capsule(s) View ingredients & interactions Ojibwa Tea by NOW Liquid 16 fl. Oz. · 473 mL View ingredients & interactions Ojibwa Tea by Baar Nature's Blessing Liquid 16 Fluid Ounce(s) · 473 mL View ingredients & interactions Ojibwa Tea by NOW Liquid 16 Fluid Ounce(s) · 473 Milliliter(s) View ingredients & interactions Ojibwa Tea Capsules by Zazzee Naturals Capsule 180 Veggie Cap(s) View ingredients & interactions Ojibwa Tea Concentrate by BIOVEA Liquid 437 mL · 16 fl. Oz. View ingredients & interactions Ojibwa-Essiac Tea Elixir by California Academy of Health Liquid 8 fl. Oz. · 237 mL View ingredients & interactions Organic Essential Detox by Renew Life Liquid 16.2 fl. Oz. · 480 mL View ingredients & interactions Organic Essiac Tea by Swanson Powder 4 Ounce(s) · 113 Gram(s) View ingredients & interactions PC-C by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions PC-C by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Rene's Tea by Oregon's Wild Harvest Powder 4 Ounce(s) · 113 Gram(s) View ingredients & interactions Rene's Tea by Oregon's Wild Harvest Other (e.g. Tea Bag) 4 Ounce(s) · 113 Gram(s) View ingredients & interactions Sheep Sorrel by Herb Pharm Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Sheep Sorrel by Herbal Terra Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Sheep Sorrel by Herbal Terra Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Sheep Sorrel by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Sheep Sorrel by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions
Pharmacist Counseling Corner

Sorrel: Common Questions

What is Sorrel used for, and does it work?
People use Sorrel for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Sorrel interact with prescription medications?
Yes. We list 169 medications with a known interaction with Sorrel. Use the checker above to see how Sorrel interacts with a specific drug.
How are Sorrel interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Sorrel with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Sorrel interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Sorrel used for?
People use Sorrel mainly as a tangy culinary herb, and in traditional medicine for fever, congestion, digestion, inflammation, and skin issues. It is also an ingredient in some herbal sinus products, though strong human proof for most uses is lacking.
Is Sorrel safe to eat?
For most healthy people, Sorrel is safe in normal food amounts. Its high oxalate content means large or concentrated amounts should be avoided, especially if you are prone to kidney stones.
Can Sorrel cause kidney stones?
Sorrel is high in oxalate, which can contribute to kidney stones in some people, particularly with large or frequent intake. If you have a history of kidney stones or kidney disease, talk to your doctor before using it regularly.
Can I take Sorrel while pregnant or breastfeeding?
Using Sorrel as an ordinary food ingredient is likely fine, but concentrated or medicinal amounts have not been proven safe. To be cautious, avoid Sorrel supplements during pregnancy and breastfeeding unless your doctor approves.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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