Medication interaction hub

What Supplements Interact with Mometasone, formoterol?

Mometasone, formoterol brand name: Zenhale. Every interaction below applies to the brands too.

155 Interactions 2 Major 120 Moderate 33 Minor

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Mometasone and formoterol (Zenhale) is an inhaled asthma controller, a steroid paired with a long-acting airway opener, and its supplement list calls for real vigilance rather than a shrug. Nearly everything on it acts on the liver enzymes that break these medicines down, chiefly one called CYP3A4. Both major-rated entries sit right there, and both are everyday items: grapefruit can push drug levels up, and steroid side effects with them, while St. John's wort speeds the breakdown until the inhaler may quietly lose ground against your asthma.

Of the 155 ingredients on file, only those two rate major; 120 are moderate and 33 minor, most working through related liver enzymes on evidence that is often lab research rather than human studies. A shift in either direction matters, since extra steroid exposure and weaker asthma control are each real problems. Grapefruit juice at breakfast is the habit worth rethinking first.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Mometasone, formoterol: Top Interactions at a Glance

The most significant Mometasone, formoterol supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 155 interacting ingredients — plus 1,297 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Mometasone, formoterol + supplement combinations in our database, best-documented first. Open any card for the full report.

The complete list

Every Supplement Checked Against Mometasone, formoterol

All 1,452 ingredients in our database, ranked by severity — 155 with a Mometasone, formoterol interaction on file and 1,297 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Straight answers

Can You Take It With Mometasone, formoterol?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Ostarine with Mometasone, formoterol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, ostarine might increase levels of drugs metabolized by CYP2C9, although clinical research suggests this is not clinically rel...

Full Ostarine + Mometasone, formoterol answer

Can you take Polypodium Leucotomos with Mometasone, formoterol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Polypodium leucotomos might increase levels of drugs metabolized by CYP3A4.

Full Polypodium Leucotomos + Mometasone, formoterol answer

Can you take Red Clover with Mometasone, formoterol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, red clover might increase the levels and clinical effects of drugs metabolized by CYP2C19.

Full Red Clover + Mometasone, formoterol answer

Can you take Soy with Mometasone, formoterol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Soy might modestly induce CYP2C9 enzymes.

Full Soy + Mometasone, formoterol answer

Can you take Tangerine with Mometasone, formoterol?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).

Full Tangerine + Mometasone, formoterol answer

Can you take Grapefruit with Mometasone, formoterol?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Full Grapefruit + Mometasone, formoterol answer

Can you take St. John's Wort with Mometasone, formoterol?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. St.

Full St. John's Wort + Mometasone, formoterol answer

Can you take Ayahuasca with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, ayahuasca might increase plasma concentrations of CYP2D6 substrates.

Full Ayahuasca + Mometasone, formoterol answer

Can you take Cannabidiol (cbd) with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Cannabidiol may increase levels of drugs metabolized by CYP2C19.

Full Cannabidiol (cbd) + Mometasone, formoterol answer

Can you take Ginkgo with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, ginkgo might decrease levels of drugs metabolized by CYP2C19.

Full Ginkgo + Mometasone, formoterol answer

Can you take Goldenseal with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Goldenseal might increase serum levels of drugs metabolized by CYP2D6.

Full Goldenseal + Mometasone, formoterol answer

Can you take Guggul with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guggul might reduce the effects of CYP3A4 substrates.

Full Guggul + Mometasone, formoterol answer

Can you take Melatonin with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, melatonin might increase levels of drugs metabolized by CYP2C19.

Full Melatonin + Mometasone, formoterol answer

Can you take Schisandra with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, schisandra might increase the levels and clinical effects of CYP2C19 substrates.

Full Schisandra + Mometasone, formoterol answer

Can you take Syrian Rue with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might increase the levels and clinical effects of drugs metabolized by CYP2D6.

Full Syrian Rue + Mometasone, formoterol answer

Can you take Tree Turmeric with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tree turmeric might increase the levels and clinical effects of drugs that are substrates of CYP3A4.

Full Tree Turmeric + Mometasone, formoterol answer

Can you take 1,3-dmaa with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. 1,3-DMAA strongly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.

Full 1,3-dmaa + Mometasone, formoterol answer

Can you take Acacia Rigidula with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP2D6 su...

Full Acacia Rigidula + Mometasone, formoterol answer

Can you take Active Hexose Correlated Compound (ahcc) with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, AHCC might increase levels of drugs metabolized by CYP2D6.

Full Active Hexose Correlated Compound (ahcc) + Mometasone, formoterol answer

Can you take Adrafinil with Mometasone, formoterol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, adrafinil might increase the levels and clinical effects of CYP2C19 substrates.

Full Adrafinil + Mometasone, formoterol answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Mometasone, formoterol is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Mometasone, formoterol, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Mometasone, formoterol sits in 5 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Mometasone, formoterol through this category.

Cytochrome P450 2C9 (Cyp2C9) Substrates 64 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

64 of the supplement ingredients on this page reach Mometasone, formoterol through this category.

Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

60 of the supplement ingredients on this page reach Mometasone, formoterol through this category.

Cytochrome P450 2C19 (Cyp2C19) Substrates 33 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

33 of the supplement ingredients on this page reach Mometasone, formoterol through this category.

Topical Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Mometasone, formoterol through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Mometasone, formoterol

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Mometasone, formoterol.

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Pharmacist Counseling Corner

Mometasone, formoterol & Supplements: Common Questions

What supplements interact with Mometasone, formoterol?
Our database currently documents 155 ingredients with a known Mometasone, formoterol interaction (2 major, 120 moderate, 33 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 155. The highest-ranked right now: Grapefruit, St. John's Wort, Ayahuasca.
Which Mometasone, formoterol supplement interactions are the most serious?
The 2 major-rated combinations — led by Grapefruit and St. John's Wort — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Mometasone, formoterol?
Plenty of supplements coexist fine with Mometasone, formoterol; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Zenhale have the same supplement interactions as Mometasone, formoterol?
Yes — Zenhale all contain Mometasone, formoterol, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Mometasone, formoterol and my other medications?
This page covers Mometasone, formoterol against supplements and herbal ingredients. Checking Mometasone, formoterol against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 29, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.