Drug Interactions Directory
2,618 drugs with documented interactions.
2,618Drugs
67,117Interactions
53,805Serious (major+)
PharmacistReviewed
1Look up a drugSearch by generic or brand name, or browse A-Z.
2Scan the severityInteractions are grouped and color-coded by how much they matter.
3Read the write-upPlain-English and clinical explanations, with cited evidence.
Popular:
Buprenorphine
633
Hydroxychloroquine
631
Ketoconazole Topical
546
Cyclosporine Injection
545
Cyclosporine Ophthalmic
545
Sertraline
532
Amitriptyline
525
Fentanyl Transdermal Patch
493
Your recent:
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
L
Levomilnacipran
63
Levonorgestrel
234
Levonorgestrel Intrauterine System
211
Levorphanol
37
Levothyroxine
214
Licorice
38
Lidocaine
33
Lidoflazine
26
Lily Of The Valley
1
Linagliptin
165
Lincomycin
1
Lindane
6
Linerixibat
3
Linezolid
47
Linezolid Injection
212
Linoleic Acid
1
Liothyronine
31
Liraglutide
44
Liraglutide Injection
89
Lisdexamfetamine
55
Lisdexamfetamine Dimesylate
1
Lisinopril
196
Lisocabtagene Maraleucel Injection
15
Lisuride
7
Lithium
71
Lithium Carbonate
317
Lithospermum
5
Lixisenatide
80
Lixisenatide Injection
174
Lobelia
3
Lofepramine
51
Lofexidine
78
Lomefloxacin
32
Lomitapide
83
Lomustine
15
Lonafarnib
146
Lonapegsomatropin-Tcgd
3
Lonapegsomatropin-Tcgd Injection
7
Loncastuximab Tesirine-Lpyl Injection
15
Loperamide
429
Lopinavir
94
Loprazolam
7
Loratadine
29
Lorazepam
31
Lorcainide
13
Lorcaserin
21
Lorlatinib
69
Lormetazepam
7
Lornoxicam
91
Losartan
146
Loteprednol
6
Loteprednol Etabonate
29
Loteprednol Ophthalmic
29
Lovastatin
127
Lovotibeglogene Autotemcel
4
Loxapine
33
Loxoprofen
91
Lumacaftor
97
Lumateperone
188
Lumefantrine
113
Lumiracoxib
91
Lupus Anticoagulant Assay
1
Lurasidone
135
Lurbinectedin
7
Lurbinectedin Injection
92
Lutetium Lu 177 Dotatate
36
Lutetium Lu 177 Vipivotide Tetraxetan Injection
15
Lymecycline
18
Lysine
5
M
Ma Huang
69
Macimorelin
108
Macitentan
58
Mafenide
2
Magaldrate
55
Magnesium
22
Magnesium Carbonate
53
Magnesium Hydroxide
53
Magnesium Oxide
51
Magnesium Oxybate
25
Magnesium Peroxide
16
Magnesium Salicylate
18
Magnesium Sulfate
25
Magnesium Trisilicate
52
Magnolia
4
Manidipine
8
Mannitol
4
Maprotiline
22
Maralixibat
4
Maraviroc
94
Margetuximab
4
Margetuximab-Cmkb Injection
24
Maribavir
28
Mate
2
Mavacamten
146
Mavorixafor
115
Mazindol
2
Meadowsweet
37
Measles Virus Vaccine, Live
204
Mebendazole
4
Mebeverine
1
Mebhydrolin
1
Mecamylamine
1
Mechlorethamine Topical
16
Meclizine
29
Meclocycline
17
Meclofenamate
290
Medazepam
7
Medroxyprogesterone
108
Medroxyprogesterone Injection
103
Medrysone
5
Mefenamic Acid
309
Mefloquine
256
Megestrol
2
Melatonin
23
Melitracen
47
Meloxicam
347
Meloxicam Injection
306
Melperone
21
Melphalan
156
Melphalan Flufenamide Injection
15