Medication interaction hub

What Supplements Interact with Benazepril, Hydrochlorothiazide?

Benazepril, Hydrochlorothiazide brand name: Lotensin HCT. Every interaction below applies to the brands too.

238 Interactions 11 Major 200 Moderate 27 Minor
Curated & coded by · Clinical Pharmacist · Updated September 15, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Benazepril, Hydrochlorothiazide? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Benazepril, Hydrochlorothiazide against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Lotensin HCT (benazepril with hydrochlorothiazide) lowers blood pressure two ways at once, and that is exactly why this list deserves a careful read rather than a skim. Most of the interacting supplements either stack on that effect and drop pressure too far, or push against it and undo the control the drug provides. A smaller cluster strains the kidneys or shifts electrolytes in the wrong direction, and even ordinary calcium belongs on the watch list because the thiazide half makes the body hold onto it.

Activated charcoal earns a specific mention too, since it can soak up medication in the gut and blunt the dose you actually absorb. About twenty ingredients also add sun sensitivity on top of what hydrochlorothiazide already causes. Read the eleven major entries first; the remaining 227 split into 200 moderates and 27 minors, most of them the additive blood pressure kind.

— , Clinical Pharmacist · July 18, 2026

Major 11 Moderate 200 Minor 27 No known interaction 1,214

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Benazepril, Hydrochlorothiazide: Top Interactions at a Glance

The Benazepril, Hydrochlorothiazide supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 238 interacting ingredients — plus 1,214 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Benazepril, Hydrochlorothiazide Combinations Today

The Benazepril, Hydrochlorothiazide + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Green Tea + Benazepril, Hydrochlorothiazidei

Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.

Read the full interaction Moderate Likelihood Possible Black Hellebore + Benazepril, Hydrochlorothiazidei

Theoretically, concomitant use of potassium depleting diuretics and black hellebore can increase the risk of cardiac glycoside toxicity due to potassium depleti...

Read the full interaction Moderate Likelihood Likely Potassium + Benazepril, Hydrochlorothiazidei

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.

Read the full interaction Moderate Likelihood Probable Calcium + Benazepril, Hydrochlorothiazidei

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Read the full interaction Major Likelihood Likely American Hellebore + Benazepril, Hydrochlorothiazidei

American hellebore can have potent cardiovascular effects due to the toxic steroid ester alkaloids it contains.

Read the full interaction Major Likelihood Likely Para-aminobenzoic Acid (paba) + Benazepril, Hydrochlorothiazidei

Theoretically, concomitant use of PABA and sulfonamide antibiotics inhibits the antibacterial effects of sulfonamide.

Read the full interaction
The complete list

Every Supplement Checked Against Benazepril, Hydrochlorothiazide

All 1,452 ingredients in our database, ranked by severity — 238 with a Benazepril, Hydrochlorothiazide interaction on file and 1,214 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Benazepril, Hydrochlorothiazide?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Green Tea with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.

Full Green Tea + Benazepril, Hydrochlorothiazide answer

Can you take Black Hellebore with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of potassium depleting diuretics and black hellebore can increase the risk of cardiac glycoside toxicity due...

Full Black Hellebore + Benazepril, Hydrochlorothiazide answer

Can you take Potassium with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Using ACEIs with high doses of potassium increases the risk of hyperkalemia.

Full Potassium + Benazepril, Hydrochlorothiazide answer

Can you take Calcium with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Full Calcium + Benazepril, Hydrochlorothiazide answer

Can you take Hesperidin with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking hesperidin with antihypertensive drugs might increase the risk of hypotension.

Full Hesperidin + Benazepril, Hydrochlorothiazide answer

Can you take Hibiscus Sabdariffa with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Hibiscus sabdariffa with antihypertensive drugs might increase the risk of hypotension.

Full Hibiscus Sabdariffa + Benazepril, Hydrochlorothiazide answer

Can you take Hoodia with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research shows that hoodia can increase blood pressure.

Full Hoodia + Benazepril, Hydrochlorothiazide answer

Can you take Horny Goat Weed with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, horny goat weed might increase the risk of hypotension.

Full Horny Goat Weed + Benazepril, Hydrochlorothiazide answer

Can you take Horsetail with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.

Full Horsetail + Benazepril, Hydrochlorothiazide answer

Can you take Ilex Guayusa with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk of hypokalemia.

Full Ilex Guayusa + Benazepril, Hydrochlorothiazide answer

Can you take Indian Cassia with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Indian cassia might increase the risk of potassium depletion in patients taking diuretic drugs.

Full Indian Cassia + Benazepril, Hydrochlorothiazide answer

Can you take Indian Snakeroot with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of Indian snakeroot and antihypertensive drugs might increase the risk of hypotension.

Full Indian Snakeroot + Benazepril, Hydrochlorothiazide answer

Can you take Isopropylnorsynephrine with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, isopropylnorsynephrine might decrease the effects of antihypertensive drugs.

Full Isopropylnorsynephrine + Benazepril, Hydrochlorothiazide answer

Can you take Jalap with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Jalap has diuretic effects.

Full Jalap + Benazepril, Hydrochlorothiazide answer

Can you take Khat with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Human research shows that khat and its constituent, cathinone, can increase blood pressure.

Full Khat + Benazepril, Hydrochlorothiazide answer

Can you take Khella with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Khella + Benazepril, Hydrochlorothiazide answer

Can you take Kiwi with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research suggests that consuming kiwi reduces systolic and diastolic blood pressure in hypertensive individuals.

Full Kiwi + Benazepril, Hydrochlorothiazide answer

Can you take Korean Pine with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research shows that Korean pine nut oil reduces blood pressure in spontaneously hypertensive rats.

Full Korean Pine + Benazepril, Hydrochlorothiazide answer

Can you take L-citrulline with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotensio...

Full L-citrulline + Benazepril, Hydrochlorothiazide answer

Can you take Laminaria with Benazepril, Hydrochlorothiazide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, laminaria might increase the risk of hyperkalemia when taken with ACEIs.

Full Laminaria + Benazepril, Hydrochlorothiazide answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Benazepril, Hydrochlorothiazide is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Benazepril, Hydrochlorothiazide, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Benazepril, Hydrochlorothiazide sits in 10 interaction categories. Open any one to see what the group means:

Antihypertensive Drugs 119 ingredients

Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.

119 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Diuretic Drugs 73 ingredients

Medications that increase fluid loss. Supplements affecting fluid or electrolytes (like potassium) can interact with them.

73 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Ace Inhibitors (Aceis) 12 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

12 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Thiazide Diuretics 5 ingredients

Medications that increase fluid loss. Supplements affecting fluid or electrolytes (like potassium) can interact with them.

5 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Sulfonamide Antibiotics 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Benazepril, Hydrochlorothiazide through this category.

Related: does Benazepril, Hydrochlorothiazide deplete any nutrients?

Benazepril, Hydrochlorothiazide has 7 reported nutrient associations in the research literature — see the Benazepril, Hydrochlorothiazide nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Benazepril, Hydrochlorothiazide

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Benazepril, Hydrochlorothiazide.

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Pharmacist Counseling Corner

Benazepril, Hydrochlorothiazide & Supplements: Common Questions

What supplements interact with Benazepril, Hydrochlorothiazide?
In our interaction database, 238 supplement and herbal ingredients have an interaction with Benazepril, Hydrochlorothiazide on file — 11 rated major, 200 moderate, and 27 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: American Hellebore, Para-aminobenzoic Acid (paba), Siberian Cocklebur.
Which Benazepril, Hydrochlorothiazide supplement interactions are the most serious?
Focus on the major group: American Hellebore, Para-aminobenzoic Acid (paba), Siberian Cocklebur, Tyramine and Activated Charcoal, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Benazepril, Hydrochlorothiazide?
That depends entirely on which supplement. The honest answer for Benazepril, Hydrochlorothiazide is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Lotensin HCT have the same supplement interactions as Benazepril, Hydrochlorothiazide?
Yes — Lotensin HCT all contain Benazepril, Hydrochlorothiazide, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Benazepril, Hydrochlorothiazide deplete any vitamins or nutrients?
It might — Benazepril, Hydrochlorothiazide has 7 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Benazepril, Hydrochlorothiazide nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Benazepril, Hydrochlorothiazide and my other medications?
This page covers Benazepril, Hydrochlorothiazide against supplements and herbal ingredients. Checking Benazepril, Hydrochlorothiazide against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.