Medication interaction hub

What Supplements Interact with Aspirin, Caffeine, Dover's Pwd?

Aspirin, Caffeine, Dover's Pwd brand names: Acedoval, Dovacet. Every interaction below applies to the brands too.

347 Interactions 13 Major 285 Moderate 49 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Aspirin, Caffeine, Dover's Pwd? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Aspirin, Caffeine, Dover's Pwd against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

347 supplements and herbal ingredients have interactions with Aspirin, Caffeine, Dover's Pwd on file in the HelloPharmacist interaction database — 13 rated major, 285 moderate, and 49 minor. The most serious involve Grapefruit, Siberian Cocklebur, Activated Charcoal, Beer and Danshen.

Our assessment: with 13 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Aspirin, Caffeine, Dover's Pwd.

Major 13 Moderate 285 Minor 49 No known interaction 1,105

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Aspirin, Caffeine, Dover's Pwd: Top Interactions at a Glance

The Aspirin, Caffeine, Dover's Pwd supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 347 interacting ingredients — plus 1,105 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Aspirin, Caffeine, Dover's Pwd Combinations Today

The Aspirin, Caffeine, Dover's Pwd + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Niacin + Aspirin, Caffeine, Dover's Pwdi

Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Reishi Mushroom + Aspirin, Caffeine, Dover's Pwdi

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.

Read the full interaction Moderate Likelihood Possible Meadowsweet + Aspirin, Caffeine, Dover's Pwdi

Theoretically, meadowsweet might have an additive effect with other salicylate-containing drugs, such as aspirin.

Read the full interaction Moderate Likelihood Possible Capsicum + Aspirin, Caffeine, Dover's Pwdi

Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Minor Likelihood Possible Chromium + Aspirin, Caffeine, Dover's Pwdi

NSAIDs might increase chromium levels in the body.

Read the full interaction Moderate Likelihood Possible Rose Hip + Aspirin, Caffeine, Dover's Pwdi

Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Aspirin, Caffeine, Dover's Pwd

All 1,452 ingredients in our database, ranked by severity — 347 with a Aspirin, Caffeine, Dover's Pwd interaction on file and 1,105 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Aspirin, Caffeine, Dover's Pwd?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Niacin with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.

Full Niacin + Aspirin, Caffeine, Dover's Pwd answer

Can you take Reishi Mushroom with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of reishi mushroom might increase the risk of bleeding.

Full Reishi Mushroom + Aspirin, Caffeine, Dover's Pwd answer

Can you take Meadowsweet with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, meadowsweet might have an additive effect with other salicylate-containing drugs, such as aspirin.

Full Meadowsweet + Aspirin, Caffeine, Dover's Pwd answer

Can you take Capsicum with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Capsicum + Aspirin, Caffeine, Dover's Pwd answer

Can you take Chromium with Aspirin, Caffeine, Dover's Pwd?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. NSAIDs might increase chromium levels in the body.

Full Chromium + Aspirin, Caffeine, Dover's Pwd answer

Can you take Lycopene with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Full Lycopene + Aspirin, Caffeine, Dover's Pwd answer

Can you take Mace with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzym...

Full Mace + Aspirin, Caffeine, Dover's Pwd answer

Can you take Magnolia with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Magnolia + Aspirin, Caffeine, Dover's Pwd answer

Can you take Mangosteen with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.

Full Mangosteen + Aspirin, Caffeine, Dover's Pwd answer

Can you take Maral Root with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research shows that maral root tincture can reduce platelet aggregation.

Full Maral Root + Aspirin, Caffeine, Dover's Pwd answer

Can you take Maritime Pine with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Full Maritime Pine + Aspirin, Caffeine, Dover's Pwd answer

Can you take Marjoram with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that marjoram extract inhibits platelet aggregation and adhesion.

Full Marjoram + Aspirin, Caffeine, Dover's Pwd answer

Can you take Mesoglycan with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combined use might increase bleeding risk.

Full Mesoglycan + Aspirin, Caffeine, Dover's Pwd answer

Can you take Methoxylated Flavones with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Some in vitro evidence suggests that methoxylated flavones might induce CYP1A2, possibly by increasing gene transcription.

Full Methoxylated Flavones + Aspirin, Caffeine, Dover's Pwd answer

Can you take Methylsynephrine with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Methylsynephrine has cardiac stimulant effects.

Full Methylsynephrine + Aspirin, Caffeine, Dover's Pwd answer

Can you take Moringa with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.

Full Moringa + Aspirin, Caffeine, Dover's Pwd answer

Can you take Mountain Ash with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent.

Full Mountain Ash + Aspirin, Caffeine, Dover's Pwd answer

Can you take N-acetyl Cysteine (nac) with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full N-acetyl Cysteine (nac) + Aspirin, Caffeine, Dover's Pwd answer

Can you take Nattokinase with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Full Nattokinase + Aspirin, Caffeine, Dover's Pwd answer

Can you take Neem with Aspirin, Caffeine, Dover's Pwd?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, neem leaf extract might increase the levels and clinical effects of CYP1A2 substrates.

Full Neem + Aspirin, Caffeine, Dover's Pwd answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aspirin, Caffeine, Dover's Pwd is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aspirin, Caffeine, Dover's Pwd, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aspirin, Caffeine, Dover's Pwd sits in 13 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Cytochrome P450 1A2 (Cyp1A2) Substrates 79 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

79 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Stimulant Drugs 44 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

44 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Aspirin 22 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

22 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Caffeine 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Methylxanthines 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Caffeine, Dover's Pwd through this category.

Cytochrome P450 1A2 (Cyp1A2) Substrates 1 ingredient

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

1 of the supplement ingredient on this page reaches Aspirin, Caffeine, Dover's Pwd through this category.

Related: does Aspirin, Caffeine, Dover's Pwd deplete any nutrients?

Aspirin, Caffeine, Dover's Pwd has 10 reported nutrient associations in the research literature — see the Aspirin, Caffeine, Dover's Pwd nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aspirin, Caffeine, Dover's Pwd

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aspirin, Caffeine, Dover's Pwd.

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Pharmacist Counseling Corner

Aspirin, Caffeine, Dover's Pwd & Supplements: Common Questions

What supplements interact with Aspirin, Caffeine, Dover's Pwd?
Our database currently documents 347 ingredients with a known Aspirin, Caffeine, Dover's Pwd interaction (13 major, 285 moderate, 49 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 347. The highest-ranked right now: Grapefruit, Siberian Cocklebur, Activated Charcoal.
Which Aspirin, Caffeine, Dover's Pwd supplement interactions are the most serious?
The 13 major-rated combinations — led by Grapefruit, Siberian Cocklebur, Activated Charcoal, Beer and Danshen — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Aspirin, Caffeine, Dover's Pwd?
Plenty of supplements coexist fine with Aspirin, Caffeine, Dover's Pwd; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Acedoval have the same supplement interactions as Aspirin, Caffeine, Dover's Pwd?
Yes — Acedoval, Dovacet all contain Aspirin, Caffeine, Dover's Pwd, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Aspirin, Caffeine, Dover's Pwd deplete any vitamins or nutrients?
It might — Aspirin, Caffeine, Dover's Pwd has 10 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Aspirin, Caffeine, Dover's Pwd nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Aspirin, Caffeine, Dover's Pwd and my other medications?
This page covers Aspirin, Caffeine, Dover's Pwd against supplements and herbal ingredients. Checking Aspirin, Caffeine, Dover's Pwd against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.