Medication interaction hub

What Supplements Interact with Bromfenac Sodium?

Bromfenac Sodium brand names: Prolensa, Bromsite. Every interaction below applies to the brands too.

209 Interactions 4 Major 186 Moderate 19 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Bromfenac Sodium? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Bromfenac Sodium against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

The typical person using bromfenac sodium drops (Prolensa, Bromsite) has just had cataract surgery, often older and often a daily supplement taker, a combination that deserves genuine care. Bromfenac is an NSAID, and 202 of the 209 ingredients here have blood-thinning or antiplatelet activity that can stack with it and make bleeding easier. Four interactions are rated major, and two are as ordinary as beer and wine, because alcohol with an NSAID raises the risk of stomach bleeding; danshen, a traditional heart herb, is another of the four.

The remaining 186 moderate and 19 minor entries mostly rest on lab or animal evidence rather than confirmed human harm, which tempers the alarm without erasing it. Bruising more easily, or bleeding that takes longer to stop, is the signal to watch. Compare your own supplement shelf against the full list below rather than assuming eye drops are too small to matter.

— , Clinical Pharmacist · July 18, 2026

Major 4 Moderate 186 Minor 19 No known interaction 1,243

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Bromfenac Sodium: Top Interactions at a Glance

The Bromfenac Sodium supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 209 interacting ingredients — plus 1,243 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Bromfenac Sodium Combinations Today

The Bromfenac Sodium + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Possible Fever Bark + Bromfenac Sodiumi

Theoretically, combining fever bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical resear...

Read the full interaction Moderate Likelihood Possible Dandelion + Bromfenac Sodiumi

Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.

Read the full interaction Moderate Likelihood Possible Tree Of Heaven + Bromfenac Sodiumi

Theoretically, tree of heaven extract might reduce platelet aggregation and increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.

Read the full interaction Minor Likelihood Unlikely Clove + Bromfenac Sodiumi

Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Minor Likelihood Possible Rauvolfia Vomitoria + Bromfenac Sodiumi

Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.

Read the full interaction Moderate Likelihood Possible Indole-3-carbinol + Bromfenac Sodiumi

Theoretically, indole-3-carbinol might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Bromfenac Sodium

All 1,452 ingredients in our database, ranked by severity — 209 with a Bromfenac Sodium interaction on file and 1,243 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Bromfenac Sodium?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Fever Bark with Bromfenac Sodium?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, combining fever bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reporte...

Full Fever Bark + Bromfenac Sodium answer

Can you take Dandelion with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.

Full Dandelion + Bromfenac Sodium answer

Can you take Tree Of Heaven with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tree of heaven extract might reduce platelet aggregation and increase the risk of bleeding if used with antiplatelet or antic...

Full Tree Of Heaven + Bromfenac Sodium answer

Can you take Clove with Bromfenac Sodium?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Clove + Bromfenac Sodium answer

Can you take Rauvolfia Vomitoria with Bromfenac Sodium?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.

Full Rauvolfia Vomitoria + Bromfenac Sodium answer

Can you take Goat's Rue with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Laboratory research suggests that goat's rue extract can inhibit platelet aggregation.

Full Goat's Rue + Bromfenac Sodium answer

Can you take Goldenseal with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goldenseal might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Goldenseal + Bromfenac Sodium answer

Can you take Grape with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet...

Full Grape + Bromfenac Sodium answer

Can you take Guarana with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guarana may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Guarana + Bromfenac Sodium answer

Can you take Guggul with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guggul might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.

Full Guggul + Bromfenac Sodium answer

Can you take Hawthorn with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Hawthorn + Bromfenac Sodium answer

Can you take Hesperidin with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hesperidin may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Hesperidin + Bromfenac Sodium answer

Can you take Higenamine with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, higenamine might increase the risk of bleeding or bruising when taken with anticoagulant/antiplatelet drugs.

Full Higenamine + Bromfenac Sodium answer

Can you take Holy Basil with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Holy Basil + Bromfenac Sodium answer

Can you take Honeysuckle with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Honeysuckle + Bromfenac Sodium answer

Can you take Horny Goat Weed with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, horny goat weed might increase the risk of bleeding.

Full Horny Goat Weed + Bromfenac Sodium answer

Can you take Horse Chestnut with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Horse chestnut may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Horse Chestnut + Bromfenac Sodium answer

Can you take Hu Zhang with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Hu Zhang + Bromfenac Sodium answer

Can you take Indian Gooseberry with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is co...

Full Indian Gooseberry + Bromfenac Sodium answer

Can you take Indian Long Pepper with Bromfenac Sodium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.

Full Indian Long Pepper + Bromfenac Sodium answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Bromfenac Sodium is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Bromfenac Sodium, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Bromfenac Sodium sits in 3 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Bromfenac Sodium through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Bromfenac Sodium through this category.

Topical Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Bromfenac Sodium through this category.

About Bromfenac Sodium

Bromfenac ophthalmic is a nonsteroidal anti-inflammatory (NSAID) eye drop used to treat inflammation and reduce eye pain after cataract surgery.

Generic name: Bromfenac Sodium  ·  Brand names: Prolensa, Bromsite.

See the full Bromfenac Ophthalmic drug information

Related: does Bromfenac Sodium deplete any nutrients?

Bromfenac Sodium has 2 reported nutrient associations in the research literature — see the Bromfenac Sodium nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Bromfenac Sodium

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Bromfenac Sodium.

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Pharmacist Counseling Corner

Bromfenac Sodium & Supplements: Common Questions

What supplements interact with Bromfenac Sodium?
Our database currently documents 209 ingredients with a known Bromfenac Sodium interaction (4 major, 186 moderate, 19 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 209. The highest-ranked right now: Beer, Danshen, Piracetam.
Which Bromfenac Sodium supplement interactions are the most serious?
The 4 major-rated combinations — led by Beer, Danshen, Piracetam and Wine — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Bromfenac Sodium?
Plenty of supplements coexist fine with Bromfenac Sodium; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Prolensa have the same supplement interactions as Bromfenac Sodium?
Yes — Prolensa, Bromsite all contain Bromfenac Sodium, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Bromfenac Sodium deplete any vitamins or nutrients?
It might — Bromfenac Sodium has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Bromfenac Sodium nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Bromfenac Sodium and my other medications?
This page covers Bromfenac Sodium against supplements and herbal ingredients. Checking Bromfenac Sodium against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Bromfenac Ophthalmic drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.