Medication interaction hub

What Supplements Interact with Treprostinil (Inh)?

Treprostinil (Inh) brand name: Tyvaso. Every interaction below applies to the brands too.

275 Interactions 5 Major 251 Moderate 19 Minor
Curated & coded by · Clinical Pharmacist · Updated September 15, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Treprostinil (Inh)? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Treprostinil (Inh) against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Inhaled treprostinil (Tyvaso) relaxes blood vessels in the lungs to treat pulmonary hypertension, and it also blunts platelet clotting, which is why this list of 275 ingredients warrants real vigilance rather than a shrug. Two themes cover almost everything. Roughly 200 entries, including danshen and piracetam among the five rated major, may add to bleeding risk. Well over a hundred more can pull blood pressure down further or, like tyramine, push it back up and work against the drug.

Everyday items count here too. Fish oil and its components appear for modestly lowering blood pressure, a moderate concern, and moderate describes 251 of the entries, with just 19 rated minor. A small cluster of eleven may change how the body clears treprostinil through a liver enzyme called CYP2C8. Understand the five majors first, then check the rest against what you already take.

— , Clinical Pharmacist · July 18, 2026

Major 5 Moderate 251 Minor 19 No known interaction 1,177

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Treprostinil (Inh): Top Interactions at a Glance

The Treprostinil (Inh) supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 275 interacting ingredients — plus 1,177 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Treprostinil (Inh) Combinations Today

The Treprostinil (Inh) + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Blue Cohosh + Treprostinil (Inh)i

Constituents in blue cohosh might increase blood pressure by causing coronary vasoconstriction.

Read the full interaction Moderate Likelihood Unlikely Coffee + Treprostinil (Inh)i

Theoretically, coffee may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Rose Hip + Treprostinil (Inh)i

Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Cocoa + Treprostinil (Inh)i

Theoretically, taking cocoa with antihypertensive drugs might increase the risk of hypotension.

Read the full interaction Moderate Likelihood Possible Vanadium + Treprostinil (Inh)i

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Khat + Treprostinil (Inh)i

Human research shows that khat and its constituent, cathinone, can increase blood pressure.

Read the full interaction
The complete list

Every Supplement Checked Against Treprostinil (Inh)

All 1,452 ingredients in our database, ranked by severity — 275 with a Treprostinil (Inh) interaction on file and 1,177 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Treprostinil (Inh)?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Blue Cohosh with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Constituents in blue cohosh might increase blood pressure by causing coronary vasoconstriction.

Full Blue Cohosh + Treprostinil (Inh) answer

Can you take Coffee with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, coffee may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Coffee + Treprostinil (Inh) answer

Can you take Rose Hip with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.

Full Rose Hip + Treprostinil (Inh) answer

Can you take Cocoa with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking cocoa with antihypertensive drugs might increase the risk of hypotension.

Full Cocoa + Treprostinil (Inh) answer

Can you take Vanadium with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.

Full Vanadium + Treprostinil (Inh) answer

Can you take Carrageenan with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, carrageenan may increase the risk of bleeding in patients taking anticoagulant or antiplatelet drugs.

Full Carrageenan + Treprostinil (Inh) answer

Can you take Catechu with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use with antihypertensive drugs might increase the risk of hypotension.

Full Catechu + Treprostinil (Inh) answer

Can you take Ceylon Cinnamon with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.

Full Ceylon Cinnamon + Treprostinil (Inh) answer

Can you take Ceylon Leadwort with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that Ceylon leadwort might potentiate the effects of anticoagulant and antiplatelet drugs and possibly increase the ri...

Full Ceylon Leadwort + Treprostinil (Inh) answer

Can you take Chaga with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Chaga + Treprostinil (Inh) answer

Can you take Chanca Piedra with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.

Full Chanca Piedra + Treprostinil (Inh) answer

Can you take Chokeberry with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Chokeberry + Treprostinil (Inh) answer

Can you take Chrysin with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chrysin might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Chrysin + Treprostinil (Inh) answer

Can you take Cilantro with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that extracts of cilantro can inhibit platelet aggregation.

Full Cilantro + Treprostinil (Inh) answer

Can you take Cinchona with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking cinchona might increase the drug effects and risk of bleeding with anticoagulant and antiplatelet drugs.

Full Cinchona + Treprostinil (Inh) answer

Can you take Cnidium with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Laboratory research shows that osthol, a constituent of cnidium, inhibits blood clotting and the activity of platelets.

Full Cnidium + Treprostinil (Inh) answer

Can you take Coconut Water with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking coconut water with antihypertensive drugs might increase the risk of hypotension.

Full Coconut Water + Treprostinil (Inh) answer

Can you take Codonopsis with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, codonopsis liquor might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Full Codonopsis + Treprostinil (Inh) answer

Can you take Coleus with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hy...

Full Coleus + Treprostinil (Inh) answer

Can you take Coltsfoot with Treprostinil (Inh)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, excessive doses of coltsfoot may interfere with antihypertensive or cardiovascular therapy.

Full Coltsfoot + Treprostinil (Inh) answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Treprostinil (Inh) is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Treprostinil (Inh), and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Treprostinil (Inh) sits in 4 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Treprostinil (Inh) through this category.

Antihypertensive Drugs 119 ingredients

Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.

119 of the supplement ingredients on this page reach Treprostinil (Inh) through this category.

Cytochrome P450 2C8 (Cyp2C8) Substrates 11 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

11 of the supplement ingredients on this page reach Treprostinil (Inh) through this category.

Vasodilators 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Treprostinil (Inh) through this category.

About Treprostinil (Inh)

Treprostinil oral inhalation is an inhaled medicine used to improve exercise ability in adults with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD).

Generic name: Treprostinil (Inh)  ·  Brand name: Tyvaso.

See the full Treprostinil Oral Inhalation drug information

Related: does Treprostinil (Inh) deplete any nutrients?

Treprostinil (Inh) has 1 reported nutrient association in the research literature — see the Treprostinil (Inh) nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Treprostinil (Inh)

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Treprostinil (Inh).

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Pharmacist Counseling Corner

Treprostinil (Inh) & Supplements: Common Questions

What supplements interact with Treprostinil (Inh)?
More than you might expect — 275 in total, though they are far from equal: 5 are rated major, 251 moderate, and 19 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: American Hellebore, Tyramine, American Mistletoe.
Which Treprostinil (Inh) supplement interactions are the most serious?
Focus on the major group: American Hellebore, Tyramine, American Mistletoe, Danshen and Piracetam. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Treprostinil (Inh)?
Usually yes — most people on Treprostinil (Inh) can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Tyvaso have the same supplement interactions as Treprostinil (Inh)?
Yes — Tyvaso all contain Treprostinil (Inh), so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Treprostinil (Inh) deplete any vitamins or nutrients?
It might — Treprostinil (Inh) has 1 reported nutrient-depletion association in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Treprostinil (Inh) nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Treprostinil (Inh) and my other medications?
This page covers Treprostinil (Inh) against supplements and herbal ingredients. Checking Treprostinil (Inh) against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Treprostinil Oral Inhalation drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.